Abstract：
:More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common, might foment the transition from mild to critical clinical manifestations of the disease. Epidemiological, clinical, and fundamental research is needed to clarify the potential role of Mg deficiency in COVID-19.
journal_name
Magnes Resjournal_title
Magnesium researchauthors
Iotti S,Wolf F,Mazur A,Maier JAdoi
10.1684/mrh.2020.0465subject
Has Abstractpub_date
2020-05-01 00:00:00pages
21-27issue
2eissn
0953-1424issn
1952-4021pii
mrh.2020.0465journal_volume
33pub_type
杂志文章abstract：:Intracellular total Mg2+ and free Mg2+ are compartmentalized between cell organelles and within the cytosol. Different values of [Mg2+]i in the cytosol of the same cell type were measured by various investigators. A main reason for the differences is the uncertainty of the dissociation constants used for the Mg furapt...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：2006-12-01 00:00:00
abstract：:Increased white blood cell counts or leukocytosis have been observed primarily in young rats fed diets extremely low in Mg (< 60 ppm) and high in phosphorus (0.5 % P). We investigated the influence that acute and moderate Mg deficiencies have on blood leukocytes at high and low dietary phosphorus levels. For four week...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：:Lipid and protein peroxidations were investigated in female patients with magnesium deficit (MD), fibromyalgia (FM) and age matched controls: malondialdehyde and protein carbonyls (PC), as well as serum, leucocyte and erythrocyte magnesium (EMg) were assessed in 20 controls, 25 FM and 16 MD patients. MDA are unchanged...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Epidemiological studies of populations living in areas of low magnesium (Mg) intake have consistently shown a higher cardiovascular morbidity. Several hypotheses have been advanced to explain the cardioprotective properties of magnesium. Few studies, however, have analysed the relation of magnesium to haemostasis. The...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:Lactating rats fed a 0.055% Mg diet transferred 5.5 +/- SEM 0.3 mg per day of Mg into milk but remained in a slightly positive Mg balance by increasing both food consumption and fractional intestinal Mg absorption. Urinary Mg excretion increased continually during the course of lactation to values double those of non-...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1989-12-01 00:00:00
abstract：:Complex fermentable carbohydrates, such as inulin-type fructans have been shown to improve Mg2+ absorption in the hindgut and body stores. The mechanisms for this are not well understood. The newly identified transient receptor potential melastatin 6 and 7 (TRPM6 and TRPM7) channels have been shown to function in acti...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：:46 children, aged 2-6 years, with decreased magnesium concentrations in hair, were studied. Magnesium supplementation consisted of Asmag preparation for 3 months and multivitamin Multi-tabs preparation (containing magnesium, but without calcium) for the following 4 months. Control studies were performed again after 7 ...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：:Experimental studies of anxiety in animal models, and evidence of efficacious outcomes of magnesium (Mg) supplementation in the treatment of acute clinical affective disorders, has increased interest in Mg as a potential novel treatment for symptoms of mild/moderate subjective anxiety. This short review examines the e...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：10.1684/mrh.2016.0411
更新日期：2016-03-01 00:00:00
abstract：:Dependency on extracellular calcium influx in contractile response to noradrenaline has been investigated in the thoracic aorta isolated from dietary magnesium (Mg) deficient rats. Adult male Wistar rats were fed with a Mg deficient diet (0.001% Mg) for 30 days, together with control groups (0.07% Mg). The contractile...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:We have recently demonstrated in the guinea pig that preventive dietary magnesium supplement can significantly reduce impulse noise induced hearing loss by on average 18 dB. The purpose of the present study was to examine whether magnesium might also have a therapeutic effect on noise trauma. Anesthetized guinea pigs ...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：:Sodium bicarbonate is used to treat metabolic acidosis, or to induce metabolic alkalosis in sick neonates. The aim of this study was to quantify the decrease in serum concentration of ionized magnesium ([Mg2+]) when sodium bicarbonate is added to neonatal serum in vitro. Sodium bicarbonate was added to 30 cord serum s...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：:The consequences of broad-scale alterations in magnesium (Mg2+) levels on learning and memory are poorly understood. We have recently demonstrated that adult male mice maintained on an Mg2+-deficient diet exhibit reduced conditional freezing behavior. The purpose of the present study was to determine if the detrimenta...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:In therapy it is known that the combination of vitamin B6 and magnesium is beneficial in the treatment of several forms of primary magnesium deficiency. The purpose of the present study was to investigate the effect of complex magnesium supplementation containing mineral bishofit solution (MgCl2 x 6H2O) and pyridoxine...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：:The purpose of the research work was to study the influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Pregnant female rats received alpha-zearalenol at the doses of: 0.05, 0.5 or 1 mg x kg(-1) b.w. After delivery, brain, liver and kidne...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2003-06-01 00:00:00
abstract：:A protein of approximately 70-kDa was identified as a candidate Na+/Mg2+ exchanger in rumen epithelial cells (REC). Melastatin-related Transient Receptor Potential 7 (TRPM7) and Magnesium Transporter 1 (MagT1) transcripts and, from them, encoded proteins were also detected. The regulation of these Mg transport pathway...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
abstract：:Photosynthetic capacity of chloroplasts is regulated by stromal pH. The pH of the stroma must be maintained higher than external pH during illumination in order to optimize photosynthetic carbon reduction cycle activity. Stromal pH is affected by K+/H+ counterexchange across the chloroplast envelope. Magnesium ion ext...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1993-09-01 00:00:00
abstract：:The relation between histamine metabolism and an appearance of pinnal hyperaemia during magnesium (Mg) deficiency, and the effects of some factors on these were studied in 3-week-old Wistar rats. On a Mg-deficient diet (Mg 0.001%), the histamine concentrations in plasma and urine increased after 4-5 d, and reached a m...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1988-12-01 00:00:00
abstract：PURPOSE:Critically evaluate the experimental evidence and clinical trial outcomes as the basis for use of magnesium (Mg) supplements as therapy for calcium oxalate nephrolithiasis. MATERIALS AND METHODS:Literature search of MedLine and Web of Science through January 2005; articles cited in papers found by searches. R...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：2005-06-01 00:00:00
abstract：:The use of fluorescent indicators to quantify intracellular magnesium ([Mg(2+)]i) requires accurate determination of the dissociation constant (K(D)). Ideally, the K(D) should be determined intracellularly; however, in practice this is difficult to achieve. An alternative method is to measure the K(D) in solutions whi...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：:The objective of this study was to examine the influence of the endothelium on the extracellular magnesium induced relaxation of basal tension in isolated aortas from both mineralocorticoid-salt (DOCA-salt) hypertensive and control normotensive Sprague Dawley male rats. After incubation in magnesium-free physiological...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:Mg2+ is known to influence conductance and gating properties of a multitude of ion channels and is thus able to modulate synaptic transmission. Therefore, a tight regulation of the intracellular free Mg2+ concentration ([Mg2+]i) in neurones and glial cells is crucial for maintaining the functions of central nervous sy...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：2000-06-01 00:00:00
abstract：:Electrolyte abnormalities are a frequent and potentially hazardous complication in the treatment of patients with congestive heart failure. Medical treatment with diuretics and/or digitalis, as well as neurohumoral activation most likely initiated by the compromised cardiac function, contributes to this alteration. Th...
journal_title：Magnesium research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1992-03-01 00:00:00
abstract：:We evaluated the effects of oral magnesium supplementation on plasma lipid concentrations in patients with non-insulin-dependent diabetes mellitus. Twenty-six persons with non-insulin-dependent diabetes mellitus received 4.5 g magnesium pidolate/d for one month, and 17 persons received placebo. Before and at the end o...
journal_title：Magnesium research
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:A common use for high doses of oral magnesium salts is to produce a laxative effect to treat constipation. In the intestinal lumen the poorly absorbable magnesium ions (and other ions such as sulphate) exert an osmotic effect and cause water to be retained in the intestinal lumen. This increases the fluidity of the in...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1996-06-01 00:00:00
abstract：:Ninety-five patients with acute myocardial infarction were followed up for 6 months to 3 years (mean 25.4 months) in a preliminary study to compare the effects of intravenous magnesium (49 patients) with that of intravenous propranolol (44 patients) given immediately after admission to the intensive care unit. There w...
journal_title：Magnesium research
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-12-01 00:00:00
abstract：:Ageing constitutes a risk factor for magnesium deficit. Primary magnesium deficit originates from two aetiological mechanisms: deficiency and depletion. Primary magnesium deficiency is due to insufficient magnesium intake. Dietary amounts of magnesium are marginal in the whole population whatever the age. Nutritional ...
journal_title：Magnesium research
pub_type： 杂志文章,评审
doi：
更新日期：1993-12-01 00:00:00
abstract：:The complex pressure wave (blast) generated by some explosions causes pulmonary pathological changes which resemble the histological findings of the adult respiratory distress syndrome (ARDS). The development of indirect neurotrauma following experimental pulmonary blast injury has been shown previously. The purpose o...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：UNLABELLED:Magnesium (Mg) plays an important role in lymphocyte function. Low blood concentration of Mg may result in intralymphocyte imbalance and in turn may be associated with intensified apoptosis of peripheral blood lymphocytes. Due to its multistage character; extracorporeal circulation (ECC) may augment Mg disor...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：:In clinical practice diabetes mellitus is the most significant cause of hypomagnesemia and Mg depletion. The obese Zucker rat approaches non-insulin-dependent type II diabetes; lean Zucker rats being suitable controls. Using this disease model the influence of dietary Mg deficiency was studied: animals received a diet...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：:Some previous studies have reported the involvement of magnesium (Mg) deficiency in children with ADHD syndrome. In this work, 40 children with clinical symptoms of ADHD were followed clinically and biologically during a magnesium-vitamin B6 (Mg-B6) regimen (6 mg/kg/d Mg, 0.6 mg/kg/d vit-B6) which was set up for at le...
journal_title：Magnesium research
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
