Effects of oral magnesium supplementation on plasma lipid concentrations in patients with non-insulin-dependent diabetes mellitus.

Abstract:

:We evaluated the effects of oral magnesium supplementation on plasma lipid concentrations in patients with non-insulin-dependent diabetes mellitus. Twenty-six persons with non-insulin-dependent diabetes mellitus received 4.5 g magnesium pidolate/d for one month, and 17 persons received placebo. Before and at the end of the treatment period cholesterol concentration, triglycerides, LDL cholesterol, HDL cholesterol, and plasma and erythrocyte magnesium were evaluated. Chronic magnesium supplementation produced a significant reduction of plasma cholesterol and LDL cholesterol, and an increase of HDL cholesterol. These results suggest that oral supplementation of magnesium may be useful in the treatment of hyperlipidaemia in patients with non-insulin-dependent diabetes mellitus.

journal_name

Magnes Res

journal_title

Magnesium research

authors

Corica F,Allegra A,Di Benedetto A,Giacobbe MS,Romano G,Cucinotta D,Buemi M,Ceruso D

subject

Has Abstract

pub_date

1994-03-01 00:00:00

pages

43-7

issue

1

eissn

0953-1424

issn

1952-4021

journal_volume

7

pub_type

临床试验,杂志文章
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    abstract::46 children, aged 2-6 years, with decreased magnesium concentrations in hair, were studied. Magnesium supplementation consisted of Asmag preparation for 3 months and multivitamin Multi-tabs preparation (containing magnesium, but without calcium) for the following 4 months. Control studies were performed again after 7 ...

    journal_title:Magnesium research

    pub_type: 杂志文章

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    authors: Kozielec T,Sałacka A,Radomska K,Strecker D,Durska G

    更新日期:2001-03-01 00:00:00

  • Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. I. Attention deficit hyperactivity disorders.

    abstract::Some previous studies have reported the involvement of magnesium (Mg) deficiency in children with ADHD syndrome. In this work, 40 children with clinical symptoms of ADHD were followed clinically and biologically during a magnesium-vitamin B6 (Mg-B6) regimen (6 mg/kg/d Mg, 0.6 mg/kg/d vit-B6) which was set up for at le...

    journal_title:Magnesium research

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    authors: Mousain-Bosc M,Roche M,Polge A,Pradal-Prat D,Rapin J,Bali JP

    更新日期:2006-03-01 00:00:00

  • Magnesium supplements may enhance the effect of antihypertensive medications in stage 1 hypertensive subjects.

    abstract:UNLABELLED:Comprehensive analytical review of 44 human studies in 43 publications of oral Magnesium (Mg) therapy for hypertension (HT) shows Mg supplements may enhance the blood-pressure (BP) lowering effect of anti-hypertensive medications (medications) in Stage 1 HT subjects. 9 studies conducted on subjects treated w...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2010.0198

    authors: Rosanoff A

    更新日期:2010-03-01 00:00:00

  • Intravenous magnesium sulphate effect on maternal serum and amniotic fluid cytokines levels in preterm labour patients.

    abstract::Our objective was to evaluate the effect of intravenous magnesium sulphate administration to patients with preterm labour on maternal serum and amniotic fluid IL-1beta, IL-6, IL-10 and TNFalpha concentrations. Thirty-six patients at 24-34 weeks of singleton gestation, who presented with contractions (> or = 8 in 60 mi...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Mezad D,Hallak M,Huleihel M,Gortzak-Uzan L,Smolin A,Mazor M

    更新日期:2002-12-01 00:00:00

  • Mechanisms of Mg2+ influx, efflux and intracellular 'muffling' in leech neurones and glial cells.

    abstract::Mg2+ is known to influence conductance and gating properties of a multitude of ion channels and is thus able to modulate synaptic transmission. Therefore, a tight regulation of the intracellular free Mg2+ concentration ([Mg2+]i) in neurones and glial cells is crucial for maintaining the functions of central nervous sy...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Günzel D,Schlue WR

    更新日期:2000-06-01 00:00:00

  • Are the transient receptor potential melastatin (TRPM) channels important in magnesium homeostasis following traumatic brain injury?

    abstract::Traumatic brain injury (TBI) confers a major burden to Western society and effective treatments are urgently required to improve the long-term deficits that inflict TBI survivors. Depletion of intracellular Mg(2+) is a well-known phenomenon occurring after TBI and is associated with poor neurological outcome. However,...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:10.1684/mrh.2009.0189

    authors: Cook NL,Van Den Heuvel C,Vink R

    更新日期:2009-12-01 00:00:00

  • Effect of magnesium supplementation containing mineral bishofit (MgCl2 x 6H2O) solution and pyridoxine hydrochloride on erythrocyte magnesium depletion and behaviour of rats after three-month alcoholization.

    abstract::In therapy it is known that the combination of vitamin B6 and magnesium is beneficial in the treatment of several forms of primary magnesium deficiency. The purpose of the present study was to investigate the effect of complex magnesium supplementation containing mineral bishofit solution (MgCl2 x 6H2O) and pyridoxine...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Iezhitsa IN,Onishchenko NV,Churbakova NV,Parshev VV,Petrov VI,Spasov AA

    更新日期:2002-12-01 00:00:00

  • Recent data on mitral valve prolapse and magnesium deficit.

    abstract::Idiopathic mitral valve prolapse (IMVP) is a widespread disease. IMVP may be latent, but most patients describe a great variety of symptoms. The clinical pictures of IMVP and of latent tetany are superimposed with regard to Mg deficit. IMVP appears as a late complication of latent tetany due to magnesium deficit (LTMD...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Zeana CD

    更新日期:1988-12-01 00:00:00

  • Association between low serum magnesium concentration and hyperuricemia.

    abstract:OBJECTIVES:To examine the cross-sectional associations between serum magnesium (Mg) and hyperuricemia (HU). METHODS:2904 subjects were included in this study. HU was defined as uric acid ≥416 μmol/L for the male population and ≥360 μmol/L for the female population. A multivariable logistic analysis model was applied t...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0384

    authors: Zeng C,Wang YL,Wei J,Yang T,Li H,Xie DX,Li YS,Lei GH

    更新日期:2015-06-01 00:00:00

  • Experimental magnesium depletion in adult rabbits caused by blast overpressure.

    abstract::The complex pressure wave (blast) generated by some explosions causes pulmonary pathological changes which resemble the histological findings of the adult respiratory distress syndrome (ARDS). The development of indirect neurotrauma following experimental pulmonary blast injury has been shown previously. The purpose o...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Cernak I,Radosevic P,Malicevic Z,Savic J

    更新日期:1995-09-01 00:00:00

  • Magnesium fluxes during lactation in the rat.

    abstract::Lactating rats fed a 0.055% Mg diet transferred 5.5 +/- SEM 0.3 mg per day of Mg into milk but remained in a slightly positive Mg balance by increasing both food consumption and fractional intestinal Mg absorption. Urinary Mg excretion increased continually during the course of lactation to values double those of non-...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Brommage R

    更新日期:1989-12-01 00:00:00

  • Magnesium deficiency reduces fear-induced conditional lick suppression in mice.

    abstract::The consequences of broad-scale alterations in magnesium (Mg2+) levels on learning and memory are poorly understood. We have recently demonstrated that adult male mice maintained on an Mg2+-deficient diet exhibit reduced conditional freezing behavior. The purpose of the present study was to determine if the detrimenta...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Bardgett ME,Schultheis PJ,Muzny A,Riddle MD,Wagge JR

    更新日期:2007-03-01 00:00:00

  • Effects of Mg2+, pH and PCr on cardiac excitation-metabolic coupling.

    abstract::A tight coupling between ionic currents, intracellular Ca2+ homeostasis, cytosolic [ADP] and deltaG of ATP hydrolysis underlies the regulation of cardiac cell function. As more experimental detail on the biochemistry and biophysics of these complex processes and their interactions accumulates, the intuitive interpreta...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Michailova A,McCulloch AD

    更新日期:2008-03-01 00:00:00

  • FAST-Mag protocol with or without mild hypothermia (35°C) does not improve outcome after permanent MCAO in rats.

    abstract::The current study assessed the neuroprotective efficacy of magnesium using a FAST-Mag trial treatment protocol alone, and in combination with mild hypothermia, in Sprague Dawley rats subjected to permanent, middle cerebral artery occlusion (MCAO). Treatment with magnesium (MgSO4.7H2O) consisted of an intravenous loadi...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2013.0340

    authors: Meloni BP,Cross JL,Brookes LM,Clark VW,Campbell K,Knuckey NW

    更新日期:2013-04-01 00:00:00

  • Magnesium-based implants: a mini-review.

    abstract::The goal of this review is to bring to the attention of the readership of Magnesium Research another facet of the importance of magnesium, i.e. magnesium-based biomaterials. A concise history of biomaterials and magnesium are thus presented. In addition, historical and current, clinical magnesium-based applications ar...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:10.1684/mrh.2015.0375

    authors: Luthringer BJ,Feyerabend F,Willumeit-Römer R

    更新日期:2014-10-01 00:00:00

  • Influence of graded magnesium deficiencies on white blood cell counts and lymphocyte subpopulations in rats.

    abstract::Increased white blood cell counts or leukocytosis have been observed primarily in young rats fed diets extremely low in Mg (< 60 ppm) and high in phosphorus (0.5 % P). We investigated the influence that acute and moderate Mg deficiencies have on blood leukocytes at high and low dietary phosphorus levels. For four week...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Van Orden R,Eggett DL,Franz KB

    更新日期:2006-06-01 00:00:00

  • Histamine metabolism and pinnal hyperaemia during magnesium deficiency in rats.

    abstract::The relation between histamine metabolism and an appearance of pinnal hyperaemia during magnesium (Mg) deficiency, and the effects of some factors on these were studied in 3-week-old Wistar rats. On a Mg-deficient diet (Mg 0.001%), the histamine concentrations in plasma and urine increased after 4-5 d, and reached a m...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Nishio A,Ishiguro S,Ikegaki I,Matsumoto S,Yoshimitsu F,Miyazaki A

    更新日期:1988-12-01 00:00:00

  • The influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny.

    abstract::The purpose of the research work was to study the influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Pregnant female rats received alpha-zearalenol at the doses of: 0.05, 0.5 or 1 mg x kg(-1) b.w. After delivery, brain, liver and kidne...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pasternak K,Kiełczykowska M,Sztanke M,Borzecki A

    更新日期:2003-06-01 00:00:00

  • Long-term follow-up after acute myocardial infarction in patients randomized to treatment with intravenous magnesium or intravenous propranolol in the acute phase.

    abstract::Ninety-five patients with acute myocardial infarction were followed up for 6 months to 3 years (mean 25.4 months) in a preliminary study to compare the effects of intravenous magnesium (49 patients) with that of intravenous propranolol (44 patients) given immediately after admission to the intensive care unit. There w...

    journal_title:Magnesium research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Abraham AS,Balkin J,Rosenmann D,Ilan M,Klutstein M,Zion MM

    更新日期:1994-12-01 00:00:00

  • No positive effect of oral magnesium supplementation in the decreases of inflammation in subjects with prediabetes: a pilot study.

    abstract::To determine whether oral magnesium supplementation modifies serum levels of high-sensitivity C-reactive protein (hsCRP), TNF-alpha, IL-6, and IL-10 in subjects with prediabetes, inflammation, and hypomagnesemia, a total of 26 subjects men and non-pregnant women were included and randomly allocated to receive 30 ml of...

    journal_title:Magnesium research

    pub_type: 杂志文章,随机对照试验

    doi:10.1684/mrh.2012.0322

    authors: Simental-Mendía LE,Rodríguez-Morán M,Reyes-Romero MA,Guerrero-Romero F

    更新日期:2012-07-01 00:00:00

  • Antiarrhythmic effect of parenteral magnesium on ventricular tachycardia associated with long QT syndrome.

    abstract::Magnesium deficiency has been linked with cardiac arrhythmias and sudden cardiac death. Antiarrhythmic effects of intravenous magnesium in the patients who are not hypomagnesaemic were mainly demonstrated in the patients with acquired long QT syndrome. Parenteral administration should be considered in this type of ven...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Kurita T

    更新日期:1994-06-01 00:00:00

  • Effect of bicarbonate on neonatal serum ionized magnesium in vitro.

    abstract::Sodium bicarbonate is used to treat metabolic acidosis, or to induce metabolic alkalosis in sick neonates. The aim of this study was to quantify the decrease in serum concentration of ionized magnesium ([Mg2+]) when sodium bicarbonate is added to neonatal serum in vitro. Sodium bicarbonate was added to 30 cord serum s...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Zaidenberg G,Mimouni FB,Dollberg S

    更新日期:2004-06-01 00:00:00

  • Preliminary communication on intralymphocyte ionized magnesium in hypertensive patients under treatment with beta-blockers.

    abstract::We measured free intralymphocyte magnesium (Mgi) in 10 hypertensive subjects (HS) before and after treatment with atenolol (A) and in 16 normotensive control subjects (NC). We also carried out in vitro studies on human lymphocytes to test the effect of catecholamines and beta-antagonists on Mgi. Mgi in HS was not stat...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pastori C,Delva P,Degan M,Lechi A

    更新日期:1999-03-01 00:00:00

  • Voltage dependence of the pharmacological Mg2+ block of the Ca2+ entry into vascular smooth muscle cells.

    abstract::We studied the voltage dependence of the inhibitory effects of the Ca2+ antagonist Mg2+, compared to nifedipine, on the transsarcolemmal Ca2+ uptake into primary monolayers of smooth muscle cells obtained from pig coronary arteries. The cellular Ca incorporation was analyzed by liquid scintillation. Depolarization was...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Fleckenstein-Grün G,Matyas S,Dumont L

    更新日期:1997-06-01 00:00:00

  • Triamterene may preserve lymphocyte magnesium and potassium in patients with congestive heart failure.

    abstract::Electrolyte abnormalities are a frequent and potentially hazardous complication in the treatment of patients with congestive heart failure. Medical treatment with diuretics and/or digitalis, as well as neurohumoral activation most likely initiated by the compromised cardiac function, contributes to this alteration. Th...

    journal_title:Magnesium research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Schwinger RH,Antoni DH

    更新日期:1992-03-01 00:00:00

  • Magnesium and selected parameters of the non-enzymatic antioxidant and immune systems and oxidative stress intensity in the seminal plasma of fertile males.

    abstract:INTRODUCTION:The present study investigated associations between environmental exposure to magnesium (Mg) and the levels of oxidative stress parameters and selected cytokines, and the antioxidant defense system in the seminal plasma of fertile males. MATERIALS AND METHODS:The study population consisted of 57 healthy, ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0377

    authors: Kasperczyk A,Dobrakowski M,Zalejska-Fiolka J,Horak S,Birkner E

    更新日期:2015-01-01 00:00:00

  • TRPM7 involvement in cancer: a potential prognostic factor.

    abstract::Calcium (Ca(2+)) and magnesium (Mg(2+)) are important metal elements that regulate a variety of cellular processes such as proliferation, migration, and apoptosis, in cancer cells. Among the ionic channels mediating intracellular entry, the transient receptor potential melastatin type 7 (TRPM7) channel is of particula...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2014.0367

    authors: Dhennin-Duthille I,Gautier M,Korichneva I,Ouadid-Ahidouch H

    更新日期:2014-07-01 00:00:00

  • The relationship between magnesium and calciotropic hormones.

    abstract::There is an important functional link between magnesium and calciotropic hormones. PTH stimulates magnesium reabsorption in the renal tubule, absorption in the gut and release of the ion from bone. Magnesium on the other hand is essential for the normal function of the parathyroid glands, metabolism of vitamin D and a...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Zofková I,Kancheva RL

    更新日期:1995-03-01 00:00:00

  • Magnesium attenuates carbon tetrachloride-induced hepatic injury in rats.

    abstract::In the present study, we investigated the protective effects of magnesium sulfate (MgSO4) against carbon tetrachloride (CCl4)-induced liver damage in rats. MgSO4 (0.001, 0.01, 0.05 and 0.1 Mg(2+) g/kg b.wt.) was administered intragastrically for 28 consecutive days to male, CCl4-treated rats. The hepatoprotective acti...

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    pub_type: 杂志文章

    doi:10.1684/mrh.2014.0350

    authors: Eidi A,Mortazavi P,Moradi F,Rohani AH,Safi S

    更新日期:2013-10-01 00:00:00

  • Magnesium and phase angle: a prognostic tool for monitoring cellular integrity in judo athletes.

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    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0389

    authors: Matias CN,Monteiro CP,Santos DA,Martins F,Silva AM,Laires MJ,Sardinha LB

    更新日期:2015-07-01 00:00:00