Intravenous magnesium sulphate effect on maternal serum and amniotic fluid cytokines levels in preterm labour patients.

Abstract:

:Our objective was to evaluate the effect of intravenous magnesium sulphate administration to patients with preterm labour on maternal serum and amniotic fluid IL-1beta, IL-6, IL-10 and TNFalpha concentrations. Thirty-six patients at 24-34 weeks of singleton gestation, who presented with contractions (> or = 8 in 60 min) had amniocentesis to rule out intrauterine infection. The patients received intravenous MgSO4 for tocolysis. Twenty-six patients had amniocentesis performed before initiation of MgSO4 (controls) while 10 others had the procedure during tocolytic therapy (study patients). Magnesium, IL-1beta, IL-6, TNFalpha and IL-10 concentrations were measured. Study and control groups were statistically compared using Student t test. Mean magnesium levels were significantly higher in the study group (P < 0.01). There were no significant differences between the cytokines levels in maternal serum and in amniotic fluid between the groups. Our results suggest that the mechanism of magnesium as a tocolytic agent may not be mediated via the examined cytokines.

journal_name

Magnes Res

journal_title

Magnesium research

authors

Mezad D,Hallak M,Huleihel M,Gortzak-Uzan L,Smolin A,Mazor M

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

247-52

issue

3-4

eissn

0953-1424

issn

1952-4021

journal_volume

15

pub_type

杂志文章
  • Mechanisms of Mg2+ influx, efflux and intracellular 'muffling' in leech neurones and glial cells.

    abstract::Mg2+ is known to influence conductance and gating properties of a multitude of ion channels and is thus able to modulate synaptic transmission. Therefore, a tight regulation of the intracellular free Mg2+ concentration ([Mg2+]i) in neurones and glial cells is crucial for maintaining the functions of central nervous sy...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Günzel D,Schlue WR

    更新日期:2000-06-01 00:00:00

  • Protein peroxidation, magnesium deficiency and fibromyalgia.

    abstract::Lipid and protein peroxidations were investigated in female patients with magnesium deficit (MD), fibromyalgia (FM) and age matched controls: malondialdehyde and protein carbonyls (PC), as well as serum, leucocyte and erythrocyte magnesium (EMg) were assessed in 20 controls, 25 FM and 16 MD patients. MDA are unchanged...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Eisinger J,Zakarian H,Pouly E,Plantamura A,Ayavou T

    更新日期:1996-12-01 00:00:00

  • The effects of magnesium supplementation on subjective anxiety.

    abstract::Experimental studies of anxiety in animal models, and evidence of efficacious outcomes of magnesium (Mg) supplementation in the treatment of acute clinical affective disorders, has increased interest in Mg as a potential novel treatment for symptoms of mild/moderate subjective anxiety. This short review examines the e...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:10.1684/mrh.2016.0411

    authors: Boyle NB,Lawton CL,Dye L

    更新日期:2016-03-01 00:00:00

  • Association between low serum magnesium concentration and hyperuricemia.

    abstract:OBJECTIVES:To examine the cross-sectional associations between serum magnesium (Mg) and hyperuricemia (HU). METHODS:2904 subjects were included in this study. HU was defined as uric acid ≥416 μmol/L for the male population and ≥360 μmol/L for the female population. A multivariable logistic analysis model was applied t...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0384

    authors: Zeng C,Wang YL,Wei J,Yang T,Li H,Xie DX,Li YS,Lei GH

    更新日期:2015-06-01 00:00:00

  • Preliminary communication on intralymphocyte ionized magnesium in hypertensive patients under treatment with beta-blockers.

    abstract::We measured free intralymphocyte magnesium (Mgi) in 10 hypertensive subjects (HS) before and after treatment with atenolol (A) and in 16 normotensive control subjects (NC). We also carried out in vitro studies on human lymphocytes to test the effect of catecholamines and beta-antagonists on Mgi. Mgi in HS was not stat...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pastori C,Delva P,Degan M,Lechi A

    更新日期:1999-03-01 00:00:00

  • Magnesium and its relationship to C-reactive protein among hemodialysis patients.

    abstract::Hypomagnesaemia has been reported among patients undergoing hemodialysis (HD). Recently, a possible correlation between serum magnesium (Mg) and C-reactive protein (CRP) has been stressed. This correlation has been attributed to cytokine production and oxidative stress processes. In this study we aimed to determine th...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pakfetrat M,Malekmakan L,Roozbeh J,Haghpanah S

    更新日期:2008-09-01 00:00:00

  • Concentration, compartmentation and metabolic function of intracellular free Mg2+.

    abstract::Intracellular total Mg2+ and free Mg2+ are compartmentalized between cell organelles and within the cytosol. Different values of [Mg2+]i in the cytosol of the same cell type were measured by various investigators. A main reason for the differences is the uncertainty of the dissociation constants used for the Mg furapt...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Günther T

    更新日期:2006-12-01 00:00:00

  • Acute myocardial infarction severity, complications, and mortality associated with lack of magnesium intake through consumption of desalinated seawater.

    abstract::Drinking water (DW) is an important dietary source of magnesium. Israel has recently increased desalinated seawater (DSW) production for DW, but negligible magnesium content in DSW may pose a risk of hypomagnesemia and consequential adverse cardiovascular effects. Consecutive acute myocardial infarction (AMI) patients...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2019.0449

    authors: Shlezinger M,Amitai Y,Goldenberg I,Atar S,Shechter M

    更新日期:2019-05-01 00:00:00

  • The relationship between magnesium and calciotropic hormones.

    abstract::There is an important functional link between magnesium and calciotropic hormones. PTH stimulates magnesium reabsorption in the renal tubule, absorption in the gut and release of the ion from bone. Magnesium on the other hand is essential for the normal function of the parathyroid glands, metabolism of vitamin D and a...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Zofková I,Kancheva RL

    更新日期:1995-03-01 00:00:00

  • Voltage dependence of the pharmacological Mg2+ block of the Ca2+ entry into vascular smooth muscle cells.

    abstract::We studied the voltage dependence of the inhibitory effects of the Ca2+ antagonist Mg2+, compared to nifedipine, on the transsarcolemmal Ca2+ uptake into primary monolayers of smooth muscle cells obtained from pig coronary arteries. The cellular Ca incorporation was analyzed by liquid scintillation. Depolarization was...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Fleckenstein-Grün G,Matyas S,Dumont L

    更新日期:1997-06-01 00:00:00

  • Angiotensin converting enzyme inhibitors, thiazide diuretics and magnesium balance. A preliminary study.

    abstract::Serum and mononuclear cell magnesium content were determined in a cross-sectional study performed in four groups of hypertensive patients on chronic treatment with atenolol (n = 11), enalapril (n = 10), thiazide diuretics (n = 12), or enalapril + thiazides (n = 11). Our study shows that in patients treated with the th...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Malini PL,Strocchi E,Valtancoli G,Ambrosioni E

    更新日期:1990-09-01 00:00:00

  • Rumen epithelial cells adapt magnesium transport to high and low extracellular magnesium conditions.

    abstract::A protein of approximately 70-kDa was identified as a candidate Na+/Mg2+ exchanger in rumen epithelial cells (REC). Melastatin-related Transient Receptor Potential 7 (TRPM7) and Magnesium Transporter 1 (MagT1) transcripts and, from them, encoded proteins were also detected. The regulation of these Mg transport pathway...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Schweigel M,Kuzinski J,Deiner C,Kolisek M

    更新日期:2009-09-01 00:00:00

  • The influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny.

    abstract::The purpose of the research work was to study the influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Pregnant female rats received alpha-zearalenol at the doses of: 0.05, 0.5 or 1 mg x kg(-1) b.w. After delivery, brain, liver and kidne...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pasternak K,Kiełczykowska M,Sztanke M,Borzecki A

    更新日期:2003-06-01 00:00:00

  • Magnesium supplements may enhance the effect of antihypertensive medications in stage 1 hypertensive subjects.

    abstract:UNLABELLED:Comprehensive analytical review of 44 human studies in 43 publications of oral Magnesium (Mg) therapy for hypertension (HT) shows Mg supplements may enhance the blood-pressure (BP) lowering effect of anti-hypertensive medications (medications) in Stage 1 HT subjects. 9 studies conducted on subjects treated w...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2010.0198

    authors: Rosanoff A

    更新日期:2010-03-01 00:00:00

  • Magnesium deficiency reduces fear-induced conditional lick suppression in mice.

    abstract::The consequences of broad-scale alterations in magnesium (Mg2+) levels on learning and memory are poorly understood. We have recently demonstrated that adult male mice maintained on an Mg2+-deficient diet exhibit reduced conditional freezing behavior. The purpose of the present study was to determine if the detrimenta...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Bardgett ME,Schultheis PJ,Muzny A,Riddle MD,Wagge JR

    更新日期:2007-03-01 00:00:00

  • Influence of endothelium in the in vitro vasorelaxant effect of magnesium on aortic basal tension in DOCA-salt hypertensive rat.

    abstract::The objective of this study was to examine the influence of the endothelium on the extracellular magnesium induced relaxation of basal tension in isolated aortas from both mineralocorticoid-salt (DOCA-salt) hypertensive and control normotensive Sprague Dawley male rats. After incubation in magnesium-free physiological...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Laurant P,Berthelot A

    更新日期:1992-12-01 00:00:00

  • Comparison of the antinociceptive effect of systemic versus intrathecal magnesium sulphate on spinal morphine analgesia.

    abstract::The aim of this work was to compare the possible antinociceptive effect of the intravenous (IV) versus the intrathecal (IT) administration of magnesium sulphate prior to spinal morphine analgesia. This research was conducted in two sets: First; experimentally, to compare the antinociceptive effect of IT magnesium sulp...

    journal_title:Magnesium research

    pub_type: 杂志文章,随机对照试验

    doi:10.1684/mrh.2016.0396

    authors: Messeha MM,Boshra V

    更新日期:2016-03-01 00:00:00

  • Comparison of a short irradiation (50 sec) by different wavelengths on audiogenic seizures in magnesium-deficient mice: evidence for a preventive neuroprotective effect of yellow.

    abstract::Audiogenic seizures triggered by an acoustic stimulus of determined frequency and amplitude have been described in many laboratory animals in many circumstances including magnesium deficiency. This model, recently validated, was used, in DBA/2 mice, to study the preventive neuroprotective effect of 6 wavelengths of th...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Pages N,Bac P,Maurois P,Durlach J,Agrapart C

    更新日期:2003-03-01 00:00:00

  • The COVID-19 pandemic: is there a role for magnesium? Hypotheses and perspectives.

    abstract::More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common,...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2020.0465

    authors: Iotti S,Wolf F,Mazur A,Maier JA

    更新日期:2020-05-01 00:00:00

  • Magnesium fluxes during lactation in the rat.

    abstract::Lactating rats fed a 0.055% Mg diet transferred 5.5 +/- SEM 0.3 mg per day of Mg into milk but remained in a slightly positive Mg balance by increasing both food consumption and fractional intestinal Mg absorption. Urinary Mg excretion increased continually during the course of lactation to values double those of non-...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Brommage R

    更新日期:1989-12-01 00:00:00

  • Plasma matrix metalloproteinase 9 correlates with disorders of brain magnesium homeostasis in patients undergoing coronary artery bypass surgery.

    abstract:BACKGROUND:Changes in plasma matrix metalloproteinase 9 (MMP-9) concentrations and parallel changes in brain magnesium homeostasis have not been examined in cardiac surgery patients. The purpose of the present study was to analyse these relationships in patients undergoing coronary artery bypass surgery (CABG) with ext...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2010.0219

    authors: Dabrowski W,Rzecki Z,Czajkowski M,Pilat J,Biernacka J,Kotlinska E,Pasternak K,Stążka K,Sztanke M,Sztanke K

    更新日期:2010-12-01 00:00:00

  • Recent data on mitral valve prolapse and magnesium deficit.

    abstract::Idiopathic mitral valve prolapse (IMVP) is a widespread disease. IMVP may be latent, but most patients describe a great variety of symptoms. The clinical pictures of IMVP and of latent tetany are superimposed with regard to Mg deficit. IMVP appears as a late complication of latent tetany due to magnesium deficit (LTMD...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Zeana CD

    更新日期:1988-12-01 00:00:00

  • Are age-related neurodegenerative diseases linked with various types of magnesium depletion?

    abstract::Age-related human neurodegenerative diseases are a major social and medical problem. It is therefore logical to take into consideration every theory with an overall approach to neurodegenerative diseases. This environmental proposal relies mainly on data concerning the Western Pacific amyotrophic lateral sclerosis-Par...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Durlach J,Bac P,Durlach V,Durlach A,Bara M,Guiet-Bara A

    更新日期:1997-12-01 00:00:00

  • Effect of magnesium supplementation containing mineral bishofit (MgCl2 x 6H2O) solution and pyridoxine hydrochloride on erythrocyte magnesium depletion and behaviour of rats after three-month alcoholization.

    abstract::In therapy it is known that the combination of vitamin B6 and magnesium is beneficial in the treatment of several forms of primary magnesium deficiency. The purpose of the present study was to investigate the effect of complex magnesium supplementation containing mineral bishofit solution (MgCl2 x 6H2O) and pyridoxine...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Iezhitsa IN,Onishchenko NV,Churbakova NV,Parshev VV,Petrov VI,Spasov AA

    更新日期:2002-12-01 00:00:00

  • Biomimetic study of the Ca(2+)-Mg2+ and K(+)-Li+ antagonism on biologically active sites: new methodology to study potential dependent ion exchange.

    abstract::Competitive divalent (magnesium and calcium) or monovalent (potassium, lithium and sodium) ion exchange and its influence on a membrane potential formation was studied at biological ligands (BL) such as adenosine triphosphate (ATP), asparagine (Asn) and glutamine (Gln) sites. The sites are dispersed electrochemically ...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:

    authors: Paczosa-Bator B,Stepien M,Maj-Zurawska M,Lewenstam A

    更新日期:2009-03-01 00:00:00

  • Antiarrhythmic effect of parenteral magnesium on ventricular tachycardia associated with long QT syndrome.

    abstract::Magnesium deficiency has been linked with cardiac arrhythmias and sudden cardiac death. Antiarrhythmic effects of intravenous magnesium in the patients who are not hypomagnesaemic were mainly demonstrated in the patients with acquired long QT syndrome. Parenteral administration should be considered in this type of ven...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Kurita T

    更新日期:1994-06-01 00:00:00

  • Ageing, hippocampal synaptic activity and magnesium.

    abstract::Ageing is associated with a general decline in physiological functions. Amongst the different aspects of body deterioration, cognitive impairments, and particularly defects in learning and memory, represent one of the most frequent features in the elderly. However, a great variability exists among aged subjects. Clini...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Billard JM

    更新日期:2006-09-01 00:00:00

  • Magnesium and phase angle: a prognostic tool for monitoring cellular integrity in judo athletes.

    abstract::Adequate magnesium (Mg) levels play a vital role in membrane excitability, cell contractility and metabolism, being a key nutrient for sustaining appropriate muscular contraction and performance levels in athletes. Phase angle (PhA), assessed by bioimpedance analysis (BIA), has been reported to be positively associate...

    journal_title:Magnesium research

    pub_type: 杂志文章

    doi:10.1684/mrh.2015.0389

    authors: Matias CN,Monteiro CP,Santos DA,Martins F,Silva AM,Laires MJ,Sardinha LB

    更新日期:2015-07-01 00:00:00

  • Effect of an aerobic training on magnesium, trace elements and antioxidant systems in a Down syndrome population.

    abstract::The aim of the present study was to determine the effect of an aerobic training on plasma and red blood cells' levels of magnesium, copper, selenium and zinc and on some oxidative stress parameters in a Down syndrome (DS) sample population. Sixteen young male adults with DS participated in the protocol. Among them, ei...

    journal_title:Magnesium research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Monteiro CP,Varela A,Pinto M,Neves J,Felisberto GM,Vaz C,Bicho MP,Laires MJ

    更新日期:1997-03-01 00:00:00

  • Magnesium and thermoregulation. I. Newborn and infant. Is sudden infant death syndrome a magnesium-dependent disease of the transition from chemical to physical thermoregulation?

    abstract::The sudden infant death syndrome (SIDS) remains a leading cause of death during the first year. The common epidemiological and pathological data which characterize SIDS include the curve for age at death (with 3 months as modal age), the stigmata of early maternal intrauterine injury, the seasonal predominance in wint...

    journal_title:Magnesium research

    pub_type: 杂志文章,评审

    doi:

    authors: Durlach J,Durlach V,Rayssiguier Y,Ricquier D,Goubern M,Bertin R,Bara M,Guiet-Bara A,Olive G,Mettey R

    更新日期:1991-09-01 00:00:00