The influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny.

Abstract:

:The purpose of the research work was to study the influence of alpha-zearalenol on magnesium concentration in cellular subfractions of certain tissues of female rats and their progeny. Pregnant female rats received alpha-zearalenol at the doses of: 0.05, 0.5 or 1 mg x kg(-1) b.w. After delivery, brain, liver and kidneys of female rats and their progeny were removed and magnesium concentration was measured in cellular subfractions of these tissues. Alpha-zearalenol reduced Mg-level in all the cellular subfractions of female rat tissues. In progeny tissues, alpha-zearalenol decreased magnesium concentration in nuclear subfraction only. In mitochondrial and cytosol subfractions it increased Mg-concentration. The changes in magnesium concentration were depended on alpha-zearalenol doses and tissue nature. The magnesium concentration decrease was higher in female rats than in progeny tissues.

journal_name

Magnes Res

journal_title

Magnesium research

authors

Pasternak K,Kiełczykowska M,Sztanke M,Borzecki A

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

106-10

issue

2

eissn

0953-1424

issn

1952-4021

journal_volume

16

pub_type

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