Abstract:
:Hypomagnesaemia has been reported among patients undergoing hemodialysis (HD). Recently, a possible correlation between serum magnesium (Mg) and C-reactive protein (CRP) has been stressed. This correlation has been attributed to cytokine production and oxidative stress processes. In this study we aimed to determine the relationship between serum Mg and hs-CRP levels in patients undergoing HD. This is a cross sectional study based on data collected from 58 HD patients in the Sahraee Center of Shiraz, Iran in 2007. Data were analyzed by SPSS.15, using Mann-Whitney test, Pair t-test, and Pearson's correlation coefficient. A p value of less than 0.05 was considered significant. The present study included 58 HD patients (33 M and 25 F). The mean age of our patients was 51 +/- 17.5 years old. At the start of HD, 39% of our patients had hypomagnesaemia and 60% had high hs-CRP, and 31% had both. There was a significant negative correlation between serum Mg and serum hs-CRP (p < 0.04). Also, in those who had hypomagnesaemia, hs-CRP was higher (p < 0.02). The results of this research support our hypothesis that hypomagnesaemia in pre-dialysis patients is a risk factor for sub-clinical inflammation due to hs-CRP elevation, although further studies are clearly required.
journal_name
Magnes Resjournal_title
Magnesium researchauthors
Pakfetrat M,Malekmakan L,Roozbeh J,Haghpanah Ssubject
Has Abstractpub_date
2008-09-01 00:00:00pages
167-70issue
3eissn
0953-1424issn
1952-4021journal_volume
21pub_type
杂志文章abstract::We evaluated the effects of oral magnesium supplementation on plasma lipid concentrations in patients with non-insulin-dependent diabetes mellitus. Twenty-six persons with non-insulin-dependent diabetes mellitus received 4.5 g magnesium pidolate/d for one month, and 17 persons received placebo. Before and at the end o...
journal_title:Magnesium research
pub_type: 临床试验,杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::We measured free intralymphocyte magnesium (Mgi) in 10 hypertensive subjects (HS) before and after treatment with atenolol (A) and in 16 normotensive control subjects (NC). We also carried out in vitro studies on human lymphocytes to test the effect of catecholamines and beta-antagonists on Mgi. Mgi in HS was not stat...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract::Sodium bicarbonate is used to treat metabolic acidosis, or to induce metabolic alkalosis in sick neonates. The aim of this study was to quantify the decrease in serum concentration of ionized magnesium ([Mg2+]) when sodium bicarbonate is added to neonatal serum in vitro. Sodium bicarbonate was added to 30 cord serum s...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract::The objective of this study was to examine the influence of the endothelium on the extracellular magnesium induced relaxation of basal tension in isolated aortas from both mineralocorticoid-salt (DOCA-salt) hypertensive and control normotensive Sprague Dawley male rats. After incubation in magnesium-free physiological...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract::The aim of the present study was to determine the effect of an aerobic training on plasma and red blood cells' levels of magnesium, copper, selenium and zinc and on some oxidative stress parameters in a Down syndrome (DS) sample population. Sixteen young male adults with DS participated in the protocol. Among them, ei...
journal_title:Magnesium research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1997-03-01 00:00:00
abstract::Serum and mononuclear cell magnesium content were determined in a cross-sectional study performed in four groups of hypertensive patients on chronic treatment with atenolol (n = 11), enalapril (n = 10), thiazide diuretics (n = 12), or enalapril + thiazides (n = 11). Our study shows that in patients treated with the th...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:1990-09-01 00:00:00
abstract::Adequate magnesium (Mg) levels play a vital role in membrane excitability, cell contractility and metabolism, being a key nutrient for sustaining appropriate muscular contraction and performance levels in athletes. Phase angle (PhA), assessed by bioimpedance analysis (BIA), has been reported to be positively associate...
journal_title:Magnesium research
pub_type: 杂志文章
doi:10.1684/mrh.2015.0389
更新日期:2015-07-01 00:00:00
abstract::Magnesium (Mg) deficiency strongly affects muscle performance. In judo, many athletes often undergo impressive weight changes associated with severe dehydration. Common practices used by athletes to achieve a target weight can lead to Mg deficit. This study aimed to understand the impact of Mg changes on strength from...
journal_title:Magnesium research
pub_type: 杂志文章
doi:10.1684/mrh.2010.0217
更新日期:2010-09-01 00:00:00
abstract::Electrolyte abnormalities are a frequent and potentially hazardous complication in the treatment of patients with congestive heart failure. Medical treatment with diuretics and/or digitalis, as well as neurohumoral activation most likely initiated by the compromised cardiac function, contributes to this alteration. Th...
journal_title:Magnesium research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-03-01 00:00:00
abstract::Photosynthetic capacity of chloroplasts is regulated by stromal pH. The pH of the stroma must be maintained higher than external pH during illumination in order to optimize photosynthetic carbon reduction cycle activity. Stromal pH is affected by K+/H+ counterexchange across the chloroplast envelope. Magnesium ion ext...
journal_title:Magnesium research
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-01 00:00:00
abstract::Audiogenic seizures triggered by an acoustic stimulus of determined frequency and amplitude have been described in many laboratory animals in many circumstances including magnesium deficiency. This model, recently validated, was used, in DBA/2 mice, to study the preventive neuroprotective effect of 6 wavelengths of th...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:2003-03-01 00:00:00
abstract::Dependency on extracellular calcium influx in contractile response to noradrenaline has been investigated in the thoracic aorta isolated from dietary magnesium (Mg) deficient rats. Adult male Wistar rats were fed with a Mg deficient diet (0.001% Mg) for 30 days, together with control groups (0.07% Mg). The contractile...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::In the present study, we investigated the protective effects of magnesium sulfate (MgSO4) against carbon tetrachloride (CCl4)-induced liver damage in rats. MgSO4 (0.001, 0.01, 0.05 and 0.1 Mg(2+) g/kg b.wt.) was administered intragastrically for 28 consecutive days to male, CCl4-treated rats. The hepatoprotective acti...
journal_title:Magnesium research
pub_type: 杂志文章
doi:10.1684/mrh.2014.0350
更新日期:2013-10-01 00:00:00
abstract::The consequences of broad-scale alterations in magnesium (Mg2+) levels on learning and memory are poorly understood. We have recently demonstrated that adult male mice maintained on an Mg2+-deficient diet exhibit reduced conditional freezing behavior. The purpose of the present study was to determine if the detrimenta...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract::More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common,...
journal_title:Magnesium research
pub_type: 杂志文章
doi:10.1684/mrh.2020.0465
更新日期:2020-05-01 00:00:00
abstract::The study was designed to investigate the role of magnesium (Mg) pretreatment on reduced glutathione (GSH) levels in kidney, liver and testis of mice intoxicated with cadmium (Cd). Animals were divided into four groups: I--controls, II--Cd group: mice intoxicated with Cd, III--Mg+Cd group: mice given Mg 1 h before Cd,...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:2007-09-01 00:00:00
abstract::Catechol-O-methyltransferase (COMT) is a magnesium-dependent, catecholamine-metabolizing enzyme, whose impaired activity has been positively associated with cardiovascular diseases, particularly hypertension. Consumption of some natural mineral-rich waters has been shown to exert protective effects on cardiovascular r...
journal_title:Magnesium research
pub_type: 杂志文章
doi:10.1684/mrh.2014.0369
更新日期:2014-07-01 00:00:00
abstract::Ageing is associated with a general decline in physiological functions. Amongst the different aspects of body deterioration, cognitive impairments, and particularly defects in learning and memory, represent one of the most frequent features in the elderly. However, a great variability exists among aged subjects. Clini...
journal_title:Magnesium research
pub_type: 杂志文章,评审
doi:
更新日期:2006-09-01 00:00:00
abstract:UNLABELLED:Magnesium (Mg) plays an important role in lymphocyte function. Low blood concentration of Mg may result in intralymphocyte imbalance and in turn may be associated with intensified apoptosis of peripheral blood lymphocytes. Due to its multistage character; extracorporeal circulation (ECC) may augment Mg disor...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Changes in plasma matrix metalloproteinase 9 (MMP-9) concentrations and parallel changes in brain magnesium homeostasis have not been examined in cardiac surgery patients. The purpose of the present study was to analyse these relationships in patients undergoing coronary artery bypass surgery (CABG) with ext...
journal_title:Magnesium research
pub_type: 杂志文章
doi:10.1684/mrh.2010.0219
更新日期:2010-12-01 00:00:00
abstract::Lipid and protein peroxidations were investigated in female patients with magnesium deficit (MD), fibromyalgia (FM) and age matched controls: malondialdehyde and protein carbonyls (PC), as well as serum, leucocyte and erythrocyte magnesium (EMg) were assessed in 20 controls, 25 FM and 16 MD patients. MDA are unchanged...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::Pregnancy is marked by a state of hypomagnesaemia but not much is known about the effects of maternal magnesium deprivation on the fetus. The aim of this study was therefore to measure magnesium concentrations in human myometrial and placental tissues and in different body fluids during pregnancy and at term, using at...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract::To investigate the effects of sex hormones on bone histomorphometry, and bone density (BMD), 10 week old ovariectomized (OVX), orchiectomized (ORX), and sham-operated (SHAM) rats fed a moderately magnesium-deficient fructose diet were studied. One third of the OVX and ORX rats were injected with beta-oestradiol-3-benz...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::Drinking water (DW) is an important dietary source of magnesium. Israel has recently increased desalinated seawater (DSW) production for DW, but negligible magnesium content in DSW may pose a risk of hypomagnesemia and consequential adverse cardiovascular effects. Consecutive acute myocardial infarction (AMI) patients...
journal_title:Magnesium research
pub_type: 杂志文章
doi:10.1684/mrh.2019.0449
更新日期:2019-05-01 00:00:00
abstract::A common use for high doses of oral magnesium salts is to produce a laxative effect to treat constipation. In the intestinal lumen the poorly absorbable magnesium ions (and other ions such as sulphate) exert an osmotic effect and cause water to be retained in the intestinal lumen. This increases the fluidity of the in...
journal_title:Magnesium research
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract::We studied the voltage dependence of the inhibitory effects of the Ca2+ antagonist Mg2+, compared to nifedipine, on the transsarcolemmal Ca2+ uptake into primary monolayers of smooth muscle cells obtained from pig coronary arteries. The cellular Ca incorporation was analyzed by liquid scintillation. Depolarization was...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract::Our objective was to evaluate the effect of intravenous magnesium sulphate administration to patients with preterm labour on maternal serum and amniotic fluid IL-1beta, IL-6, IL-10 and TNFalpha concentrations. Thirty-six patients at 24-34 weeks of singleton gestation, who presented with contractions (> or = 8 in 60 mi...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract:UNLABELLED:Comprehensive analytical review of 44 human studies in 43 publications of oral Magnesium (Mg) therapy for hypertension (HT) shows Mg supplements may enhance the blood-pressure (BP) lowering effect of anti-hypertensive medications (medications) in Stage 1 HT subjects. 9 studies conducted on subjects treated w...
journal_title:Magnesium research
pub_type: 杂志文章
doi:10.1684/mrh.2010.0198
更新日期:2010-03-01 00:00:00
abstract::46 children, aged 2-6 years, with decreased magnesium concentrations in hair, were studied. Magnesium supplementation consisted of Asmag preparation for 3 months and multivitamin Multi-tabs preparation (containing magnesium, but without calcium) for the following 4 months. Control studies were performed again after 7 ...
journal_title:Magnesium research
pub_type: 杂志文章
doi:
更新日期:2001-03-01 00:00:00
abstract::Although magnesium (Mg) contents are different between breast milk and formula, few studies have investigated the blood Mg level in breast fed or formula fed preterm infants. We examined the influence of feeding type on serum Mg and whole blood ionized Mg (iMg) levels in preterm infants soon after birth. We included 1...
journal_title:Magnesium research
pub_type: 杂志文章
doi:10.1684/mrh.2019.0444
更新日期:2018-11-01 00:00:00