Abstract:
:The reticuloendotheliosis viruses (REVs), originally isolated from avian species, constitute a group of retroviruses which are more closely related to mammalian retroviruses than to other avian retroviruses. The envelope glycoproteins of members of the REV group display a striking amino acid sequence identity with a group of primate oncoretroviruses which belong to a single receptor interference group and include all of the type D and some type C primate oncoretroviruses. Members of the REV group also have a broad host range which covers most avian cells and some mammalian cells, including those of simian and human origin. In view of this broad host range and the envelope sequence similarities, we investigated the cross-interference pattern between REV and primate virus groups to determine whether they utilized the same receptor. Superinfection experiments using a vector virus containing an Escherichia coli lacZ gene showed that reticuloendotheliosis and simian oncoretroviruses constitute a single receptor interference group on both human and canine cells and indicate that the viruses bind to the same receptor to initiate infection. These results suggest that this receptor binding specificity has been maintained over a wide range of retroviruses and may be responsible for the broad spread of these retroviruses between different orders of vertebrates.
journal_name
J Viroljournal_title
Journal of virologyauthors
Koo HM,Gu J,Varela-Echavarria A,Ron Y,Dougherty JPdoi
10.1128/JVI.66.6.3448-3454.1992subject
Has Abstractpub_date
1992-06-01 00:00:00pages
3448-54issue
6eissn
0022-538Xissn
1098-5514journal_volume
66pub_type
杂志文章abstract::Latency is an integral feature of the pathogenesis of cytomegalovirus infection and disease. Using in situ hybridization, we detected viral DNA in the splenic stroma of mice with acute murine cytomegalovirus (MCMV) infection but could not detect latent infection. By using enzymatic amplification of a 700-bp region of ...
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journal_title:Journal of virology
pub_type: 杂志文章
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.66.5.2631-2638.1992
更新日期:1992-05-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1128/JVI.00070-07
更新日期:2007-06-01 00:00:00
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更新日期:2000-02-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2012-09-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2018-03-28 00:00:00
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pub_type: 杂志文章,收录出版
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更新日期:1985-02-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.73.6.4611-4621.1999
更新日期:1999-06-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2014-06-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2016-08-12 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:1999-06-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:1971-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:1971-06-01 00:00:00
abstract::NK cells are key effectors of innate immunity and host survival during cytomegalovirus (CMV) infection. Innate murine CMV (MCMV) resistance in MA/My mice requires Ly49H/m157-independent H-2k-linked NK cell control. Here we show that replacement of MA/My H-2k with C57L H-2b susceptibility genes led to a remarkable loss...
journal_title:Journal of virology
pub_type: 杂志文章
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更新日期:2007-01-01 00:00:00