Identifying the determinants in the equatorial domain of Buchnera GroEL implicated in binding Potato leafroll virus.

abstract：:Human immunodeficiency virus clade C (HIV-C) accounts for >56% of all HIV infections worldwide. To investigate vaccine safety and efficacy in nonhuman primates, a pathogenic, R5-tropic, neutralization-sensitive simian-human immunodeficiency virus (SHIV) carrying HIV-C env would be desirable. We have constructed SHIV-2...

journal_title：Journal of virology

authors： Siddappa NB,Song R,Kramer VG,Chenine AL,Velu V,Ong H,Rasmussen RA,Grisson RD,Wood C,Zhang H,Kankasa C,Amara RR,Else JG,Novembre FJ,Montefiori DC,Ruprecht RM

更新日期：2009-02-01 00:00:00

abstract：:Influenza A viruses cause severe respiratory illnesses in humans and animals. Overreaction of the innate immune response to influenza virus infection results in hypercytokinemia, which is responsible for mortality and morbidity. However, the mechanism by which influenza induces hypercytokinemia is not fully understood...

journal_title：Journal of virology

authors： Ma N,Li X,Jiang H,Dai Y,Xu G,Zhang Z

更新日期：2021-01-13 00:00:00

abstract：:Natural killer (NK) cells are an important component in the control of influenza virus infection, acting to both clear virus-infected cells and release antiviral cytokines. Engagement of CD16 on NK cells by antibody-coated influenza virus-infected cells results in antibody-dependent cellular cytotoxicity (ADCC). Incre...

journal_title：Journal of virology

authors： Jegaskanda S,Vanderven HA,Tan HX,Alcantara S,Wragg KM,Parsons MS,Chung AW,Juno JA,Kent SJ

更新日期：2019-02-19 00:00:00

abstract：:Previous studies have established that chlorella viruses encode K(+) channels with different structural and functional properties. In the current study, we exploit the different sensitivities of these channels to Cs(+) to determine if the membrane depolarization observed during virus infection is caused by the activit...

journal_title：Journal of virology

authors： Frohns F,Käsmann A,Kramer D,Schäfer B,Mehmel M,Kang M,Van Etten JL,Gazzarrini S,Moroni A,Thiel G

更新日期：2006-03-01 00:00:00

abstract：:The configuration of latent varicella-zoster virus (VZV) DNA was analyzed by PCR. Template DNA for both internal and terminal VZV primers was present in a 1:1 ratio in ganglionic DNA, compared with a 15:1 ratio in DNA extracted from VZV virions, indicating that the VZV genomic termini are adjacent in latently infected...

journal_title：Journal of virology

authors： Clarke P,Beer T,Cohrs R,Gilden DH

更新日期：1995-12-01 00:00:00

abstract：:The expression of interleukin-2 (IL-2) has been implicated in the modulation of the outcome of ocular infection with herpes simplex virus type 1 (HSV-1); however, its effects remain controversial. To clarify the role of IL-2, we constructed a recombinant HSV-1 (HSV-IL-2) that expresses two copies of the murine IL-2 ge...

journal_title：Journal of virology

authors： Ghiasi H,Osorio Y,Perng GC,Nesburn AB,Wechsler SL

更新日期：2002-09-01 00:00:00

abstract：:A single phosphorylation event at T-antigen residue Thr124 regulates initiation of simian virus 40 DNA replication. To explore this regulatory process, a series of peptides were synthesized, centered on Thr124. These peptides contain a nuclear localization signal (NLS) and a recognition site for cyclin/Cdk kinases. Wh...

journal_title：Journal of virology

authors： Kim RJ,Moine S,Reese DK,Bullock PA

更新日期：2002-12-01 00:00:00

abstract：:Activation of host innate immune responses was studied in severe acute respiratory syndrome coronavirus (SCV)-infected human A549 lung epithelial cells, macrophages, and dendritic cells (DCs). In all cell types, SCV-specific subgenomic mRNAs were seen, whereas no expression of SCV proteins was found. No induction of c...

journal_title：Journal of virology

authors： Ziegler T,Matikainen S,Rönkkö E,Osterlund P,Sillanpää M,Sirén J,Fagerlund R,Immonen M,Melén K,Julkunen I

更新日期：2005-11-01 00:00:00

abstract：:It has been previously shown that rotavirus maturation and stability of the outer capsid are calcium-dependent processes. More recently, it has been hypothesized that penetration of the cell membrane is also affected by conformational changes of the capsid induced by Ca2+. In this study, we determined quantitatively t...

journal_title：Journal of virology

authors： Ruiz MC,Charpilienne A,Liprandi F,Gajardo R,Michelangeli F,Cohen J

更新日期：1996-08-01 00:00:00

abstract：:The establishment of de novo-generated patterns of DNA methylation is characterized by the gradual spreading of DNA methylation (I. Kuhlmann and W. Doerfler, J. Virol. 47:631-636, 1983; M. Toth, U. Lichtenberg, and W. Doerfler, Proc. Natl. Acad. Sci. USA 86:3728-3732, 1989; M. Toth, U. Müller, and W. Doerfler J. Mol. ...

journal_title：Journal of virology

authors： Orend G,Kuhlmann I,Doerfler W

更新日期：1991-08-01 00:00:00

abstract：:We present data that retroviral gene expression in early hematopoietic cells is subjected to transcriptional controls similar to those previously described for embryonic stem cells. Transient transfection experiments revealed that both the viral enhancer region in the U3 region of the long terminal repeat as well as a...

journal_title：Journal of virology

authors： Baum C,Hegewisch-Becker S,Eckert HG,Stocking C,Ostertag W

更新日期：1995-12-01 00:00:00

abstract：:Three drug-dependent mutants of human rhinovirus 16 (HRV16) were characterized by sequence analyses of spontaneous mutant isolates and were genetically reconstructed from a parental cDNA plasmid. These mutants formed plaques in the presence but not in the absence of the selecting antiviral drug, WIN 52035, which binds...

journal_title：Journal of virology

authors： Wang W,Lee WM,Mosser AG,Rueckert RR

更新日期：1998-02-01 00:00:00

abstract：:The internal structural proteins of retroviruses are proteolytically processed from the Gag polyprotein, which alone is able to assemble into virus-like particles when expressed in cells. All Gag proteins contain domains corresponding to the three structural proteins MA, CA, and NC. We have expressed the CA and NC dom...

journal_title：Journal of virology

authors： Campbell S,Vogt VM

更新日期：1995-10-01 00:00:00

abstract：:Mouse neuroblastoma cells containing intracisternal type A particles were treated with iododeoxyuridine and dexamethasone to induce the release of type C oncornavirus particles. For 5 days after treatment, antigenic markers and DNA polymerase activities specific to particles of each of the two types were assayed in th...

journal_title：Journal of virology

authors： Kuff EL,Lueders KK,Orenstein JM,Wilson SH

更新日期：1976-08-01 00:00:00

abstract：:BALB/c JLS V9 cells recently infected with Harvey sarcoma virus-murine leukemia virus (HSV-MuLV) complex contained unintegrated HSV linear DNA of 6.0-kilobase pair mass. The cells also contained two HSV closed circular DNA species along with MuLV-encoded linear and closed circular DNA species. HSV 6.0-kilobase pair li...

journal_title：Journal of virology

authors： Goldfarb MP,Weinberg RA

更新日期：1979-10-01 00:00:00

abstract：:The gene coding for the S protein, the smaller of the two envelope antigens of the duck hepatitis B virus (DHBV), is transcribed from a TATA-less promoter. In this study, we localized the promoter to a 245-bp segment of the genome that was capable of efficiently driving expression of a linked reporter gene upon transi...

journal_title：Journal of virology

authors： Welsheimer T,Newbold JE

更新日期：1996-12-01 00:00:00

abstract：:We have previously demonstrated that two mouse cell lines that are poorly infectible by reovirus become highly susceptible upon transfection with the gene encoding the epidermal growth factor receptor (EGFR) (J. E. Strong, D. Tang, and P. W. K. Lee, Virology 197:405-411, 1993). This enhancement of infection efficiency...

journal_title：Journal of virology

authors： Strong JE,Lee PW

更新日期：1996-01-01 00:00:00

abstract：UNLABELLED:Respiratory syncytial virus (RSV) is the most important cause of lower respiratory tract infection in young children and the leading cause of infant hospitalization worldwide. Uncontrolled response to RSV is mediated by a toll-like receptor (TLR)-mediated immune response. Resveratrol possesses anti-RSV activ...

journal_title：Journal of virology

authors： Liu T,Zang N,Zhou N,Li W,Xie X,Deng Y,Ren L,Long X,Li S,Zhou L,Zhao X,Tu W,Wang L,Tan B,Liu E

更新日期：2014-04-01 00:00:00

abstract：:We constructed a DNA fragment map of low-passage Towne strain cytomegalovirus by analyzing cross-blot hybridization and hybridizations of isolated recombinant clones. The abundant late transcripts were located on this map by hybridization of labeled total RNA of virus-infected cells to blotted DNA fragments. The most ...

journal_title：Journal of virology

authors： Davis MG,Mar EC,Wu YM,Huang ES

更新日期：1984-10-01 00:00:00

abstract：:In this study, we investigated the interaction of reovirus particles with cell membranes by using a 51Cr release assay. We confirmed prior observations (J. Borsa, B. D. Morash, M. D. Sargent, T. P. Copps, P. A. Lievaart, and J. G. Szekely, J. Gen. Virol. 45:161-170, 1979) that intermediate subviral particles (ISVPs) o...

journal_title：Journal of virology

authors： Lucia-Jandris P,Hooper JW,Fields BN

更新日期：1993-09-01 00:00:00

abstract：:Gene expression of human immunodeficiency virus (HIV) is modulated by both cellular transcription factors, which bind to cis-acting regulatory elements in the HIV-1 long terminal repeat (LTR) and the viral transactivator, tat. The enhancer element in the HIV-1 LTR which extends from -103 to -82 is critical for gene ex...

journal_title：Journal of virology

authors： Seeler JS,Muchardt C,Suessle A,Gaynor RB

更新日期：1994-02-01 00:00:00

abstract：:Translation of encephalomyocarditis virus RNA in rabbit reticulocyte lysates in the presence of N-formyl-[(35)S]methionine-tRNA(f) (Met) revealed that a small polypeptide is cleaved from the N-terminus of the capsid protein precursor, preA, by virus-coded protease activity. Therefore, this N-terminal segment comprisin...

journal_title：Journal of virology

authors： Campbell EA,Jackson RJ

更新日期：1983-01-01 00:00:00

abstract：:The trans-activator Tat proteins coded by human immunodeficiency virus type 1 (HIV-1) and HIV-2 appear to be similar in structure and function. However, the Tat protein of HIV-2 (Tat2) activates the HIV-1 long terminal repeat (LTR) less efficiently than Tat1 (M. Emerman, M. Guyader, L. Montagnier, D. Baltimore, and M....

journal_title：Journal of virology

authors： Elangovan B,Subramanian T,Chinnadurai G

更新日期：1992-04-01 00:00:00

abstract：:Due to the limited ultrastructural information about the coronavirion, little is known about the interactions acting at the interface between nucleocapsid and viral envelope. Knowing that subtle mutations in the carboxy-terminal endodomain of the M protein are already lethal, we have now probed the equivalent domain o...

journal_title：Journal of virology

authors： Bosch BJ,de Haan CA,Rottier PJ

更新日期：2004-07-01 00:00:00

abstract：:Genomic replication of the negative-strand RNA viruses is dependent upon protein synthesis. To examine the requirement for protein synthesis in replication, we developed an in vitro system that supports the genome replication of defective interfering particles of the negative-strand rhabdovirus vesicular stomatitis vi...

journal_title：Journal of virology

authors： Patton JT,Davis NL,Wertz GW

更新日期：1984-02-01 00:00:00

abstract：:The key role of the mitochondria in the regulation of cellular Ca2+ led to a study of mitochondrial Ca2+ uptake during the infection of chicken embryo cells with Semliki Forest virus. Mitochondrial Ca2+ uptake was stimulated during the first 5 h of infection but declined later in infection. The early stimulation sugge...

journal_title：Journal of virology

authors： Peterhans E,Haenggeli E,Wild P,Wyler R

更新日期：1979-01-01 00:00:00

abstract：:Infection with various human papillomaviruses (HPVs) induces cervical cancers. Cell surface heparan sulfates (HS) have been shown to serve as primary attachment receptors, and molecules with structural similarity to cell surface HS, like heparin, function as competitive inhibitors of HPV infection. Here we demonstrate...

journal_title：Journal of virology

authors： Selinka HC,Florin L,Patel HD,Freitag K,Schmidtke M,Makarov VA,Sapp M

更新日期：2007-10-01 00:00:00

abstract：:The antiviral effects of nitric oxide (NO) on Japanese encephalitis virus (JEV), a member of the family Flaviviridae, were investigated in this study. In vitro, inhibition of replication of JEV in gamma interferon-activated RAW 264.7 murine macrophages was correlated to cellular NO production. When cocultured with inf...

journal_title：Journal of virology

authors： Lin YL,Huang YL,Ma SH,Yeh CT,Chiou SY,Chen LK,Liao CL

更新日期：1997-07-01 00:00:00

abstract：:Dendritic cells (DC) are believed to play an important role in the initiation of innate and adaptive immune responses to infection, including respiratory tract infections, where respiratory DC (RDC) perform this role. In this report, we examined the susceptibilities of isolated murine RDC to influenza virus infection ...

journal_title：Journal of virology

authors： Hao X,Kim TS,Braciale TJ

更新日期：2008-05-01 00:00:00

abstract：:Alphaherpesviruses are parasites of the peripheral nervous system in their natural hosts. After the initial infection of peripheral tissues such as mucosal cells, these neurotropic viruses will invade the peripheral nervous system that innervates the site of infection via long-distance axonal transport of the viral ge...

journal_title：Journal of virology

authors： Ch'ng TH,Enquist LW

更新日期：2005-09-01 00:00:00