A functional hepatocyte nuclear factor 3 binding site is a critical component of the duck hepatitis B virus major surface antigen promoter.

abstract：:We report here the complete genomic sequence of the duck Tembusu virus (DTMUV) WJ-1 strain, isolated from Muscovy ducks. This is the first complete genome sequence of DTMUV reported in southern China. Compared with the other strains (TA, GH-2, YY5, and ZJ-407) that were previously found in eastern China, WJ-1 bears a ...

journal_title：Journal of virology

authors： Zhu W,Chen J,Wei C,Wang H,Huang Z,Zhang M,Tang F,Xie J,Liang H,Zhang G,Su S

更新日期：2012-12-01 00:00:00

abstract：UNLABELLED:Human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 encode auxiliary proteins that play important roles in viral replication, viral latency, and immune escape. The presence of auxiliary protein-encoding open reading frames (ORFs) in HTLV-3, the latest HTLV to be discovered, is unknown. Simian T-cell l...

journal_title：Journal of virology

authors： Turpin J,Journo C,Ko NL,Sinet F,Carpentier A,Galioot A,Edwards D,Vandamme AM,Gazzolo L,Duc Dodon M,Gessain A,Kashanchi F,Balansard I,Lacoste R,Mahieux R

更新日期：2015-01-15 00:00:00

abstract：UNLABELLED:Foreskin is the principal site of heterosexual HIV-1 infection in men. However, little is known about HIV-1-specific immune responses or inflammation in foreskin. To the best of our knowledge, no previous studies have assessed immune responses to candidate HIV-1 vaccines in foreskin. Using the rhesus monkey ...

journal_title：Journal of virology

authors： Balandya E,Miller AD,Beck M,Liu J,Li H,Borducchi E,Smith K,Cabral C,Stanley K,Maxfield LF,Barouch DH

更新日期：2014-04-01 00:00:00

abstract：:The recently emerged highly virulent variants of porcine epidemic diarrhea virus (PEDV) have caused colossal economic losses to the worldwide swine industry. In this study, we investigated the viral virulence determinants by constructing a series of chimeric mutants between the highly virulent strain BJ2011C and the a...

journal_title：Journal of virology

authors： Wang D,Ge X,Chen D,Li J,Cai Y,Deng J,Zhou L,Guo X,Han J,Yang H

更新日期：2018-06-13 00:00:00

abstract：:Only a few archaeal viruses have been subjected to detailed structural analyses. Major obstacles have been the extreme conditions such as high salinity or temperature needed for the propagation of these viruses. In addition, unusual morphotypes of many archaeal viruses have made it difficult to obtain further informat...

journal_title：Journal of virology

authors： Pietilä MK,Laurinavicius S,Sund J,Roine E,Bamford DH

更新日期：2010-01-01 00:00:00

abstract：UNLABELLED:Cell culture (cc)-derived hepatitis B virus (HBV) can infect differentiated HepaRG cells, but efficient infection requires addition of polyethylene glycol (PEG) during inoculation. Identification of sodium taurocholate cotransporting polypeptide (NTCP) as an HBV receptor enabled ccHBV infection of NTCP recon...

journal_title：Journal of virology

authors： Li J,Zong L,Sureau C,Barker L,Wands JR,Tong S

更新日期：2016-08-26 00:00:00

abstract：:We developed a mouse model of Borna disease to facilitate immunopathogenesis research by adaptation of Borna disease virus to mice through serial passage in mouse brain tissue. Borna disease virus replication, antibody production, inflammation, and Borna disease expression in several different strains of mice were exa...

journal_title：Journal of virology

authors： Rubin SA,Waltrip RW 2nd,Bautista JR,Carbone KM

更新日期：1993-01-01 00:00:00

abstract：UNLABELLED:The four serotypes of dengue virus (DENV) cause the most important and rapidly emerging arboviral diseases in humans. The recent phase 2b and 3 studies of a tetravalent dengue vaccine reported a moderate efficacy despite the presence of neutralizing antibodies, highlighting the need for a better understandin...

journal_title：Journal of virology

authors： Tsai WY,Durbin A,Tsai JJ,Hsieh SC,Whitehead S,Wang WK

更新日期：2015-07-01 00:00:00

abstract：:In immunocompromised patients, infection with Kaposi's sarcoma-associated herpesvirus (KSHV) can give rise to Kaposi's sarcoma and several lymphoproliferative disorders. In these tumors, KSHV establishes a latent infection in many of the rapidly proliferating and morphologically abnormal cells. Only a few viral gene p...

journal_title：Journal of virology

authors： Wong LY,Matchett GA,Wilson AC

更新日期：2004-09-01 00:00:00

abstract：:Lethal, amber mutations in T4 genes 46 and 47 cause incomplete degradation of host DNA, premature arrest of phage DNA synthesis, accumulation of abnormal DNA replication intermediates, and defective recombination. These phenotypes can be explained by the hypothesis that genes 46 and 47 control a DNA exonuclease, but i...

journal_title：Journal of virology

authors： Mickelson C,Wiberg JS

更新日期：1981-10-01 00:00:00

abstract：:trans activation of the human immunodeficiency virus type 1 long terminal repeat requires that the viral trans activator Tat interact with the trans-acting responsive region (TAR) RNA. Although the N-terminal 47 amino acids represent an independent activation domain that functions via heterologous nucleic acid-binding...

journal_title：Journal of virology

authors： Luo Y,Peterlin BM

更新日期：1993-06-01 00:00:00

abstract：:AP-1- and ATF-binding sites are cis-acting transcriptional elements within the U3 domain of the feline immunodeficiency virus (FIV) long terminal repeat (LTR) that serve as targets for cellular activation pathways and may regulate virus replication. We report that FIV LTR mutant proviruses encoding U3 deletions of the...

journal_title：Journal of virology

authors： Bigornia L,Lockridge KM,Sparger EE

更新日期：2001-01-01 00:00:00

abstract：UNLABELLED:Bovine papillomavirus 1 E6 interacts with two similar proteins that regulate cell attachment and cell migration called paxillin (PXN) and HIC-5 (also known as HIC5, ARA55, HIC-5, TSC-5, and TGFB1I1). Despite the similarity between HIC-5 and paxillin, paxillin is required for E6 to transform mouse embryo fibr...

journal_title：Journal of virology

authors： Brimer N,Wade R,Vande Pol S

更新日期：2014-09-01 00:00:00

abstract：:In cytomegalovirus-infected cells, the rate of protein synthesis was detected as two peaks. One occurred during the early phase of infection, 0 to 36 h postinfection, and the other occurred during the late phase, after the initiation of viral DNA synthesis. Double-isotopic-label difference analysis demonstrated that h...

journal_title：Journal of virology

authors： Stinski MF

更新日期：1977-09-01 00:00:00

abstract：:HTG2 hamster cells produce a defective murine sarcoma virus lacking gp70 and, consequently, viral surface projections (knobs), but the lack of knobs appears to have no effect on intramembrane particle distribution. In addition, it has been noted that the core of the virus remains in the "immature" form as a result of ...

journal_title：Journal of virology

authors： Demsey A,Collins F,Kawka D

更新日期：1980-12-01 00:00:00

abstract：:A nucleotide phosphohydrolase is firmly associated with a purified polyhedral cytoplasmic deoxyvirus, frog virus 3. This adenosine triphosphatase is distinguishable from known mammalian cell adenosine triphosphatases and from adenosine triphosphatase of an unrelated cytoplasmic replicating virus grown in the same host...

journal_title：Journal of virology

authors： Vilagines R,McAuslan BR

更新日期：1971-05-01 00:00:00

abstract：:We have identified a spliced transcript that contains sequences from the HCMV UL29 and UL28 open reading frames. It contains amino-terminal UL29 sequences followed by UL28 sequences, and it includes a poly(A) signal derived from the 3'-untranslated region following the UL26 open reading frame. UL29/28 RNA is expressed...

journal_title：Journal of virology

authors： Mitchell DP,Savaryn JP,Moorman NJ,Shenk T,Terhune SS

更新日期：2009-10-01 00:00:00

abstract：:An adenovirus vector encoding murine Fas ligand (mFasL) under an inducible control was derived. In vivo ectopic expression of mFasL in murine livers induced an inflammatory cellular infiltration. Furthermore, ectopic expression of mFasL by myocytes did not allow prolonged vector-mediated transgene expression. Thus, ec...

journal_title：Journal of virology

authors： Zhang HG,Bilbao G,Zhou T,Contreras JL,Gómez-Navarro J,Feng M,Saito I,Mountz JD,Curiel DT

更新日期：1998-03-01 00:00:00

abstract：:Mus dunni endogenous virus (MDEV) is activated from cells of the Asian wild mouse M. dunni (also known as Mus terricolor) in response to treatment with either 5-iodo-2'-deoxyuridine or hydrocortisone. MDEV represents a new murine retrovirus interference group and thus appears to use a different receptor for entry into...

journal_title：Journal of virology

authors： Bonham L,Wolgamot G,Miller AD

更新日期：1997-06-01 00:00:00

abstract：:cis-Acting elements in the viral genome RNA (vRNA) are essential for the translation, replication, and/or encapsidation of RNA viruses. In this study, a novel conserved cis-acting element was identified in the capsid-coding region of mosquito-borne flavivirus. The downstream of 5' cyclization sequence (5'CS) pseudokno...

journal_title：Journal of virology

authors： Liu ZY,Li XF,Jiang T,Deng YQ,Zhao H,Wang HJ,Ye Q,Zhu SY,Qiu Y,Zhou X,Qin ED,Qin CF

更新日期：2013-06-01 00:00:00

abstract：:Intramuscular administration of inactivated influenza virus vaccine is the main vaccine platform used for the prevention of seasonal influenza virus infection. In clinical trials, inactivated H5N1 vaccines have been shown to be safe and capable of eliciting immune correlates of protection. However, the H5N1 vaccines a...

journal_title：Journal of virology

authors： Lau YF,Tang LH,McCall AW,Ooi EE,Subbarao K

更新日期：2010-09-01 00:00:00

abstract：:Lymphomas induced by pure HIX murine leukemia virus in two mouse strains contained large amounts of virus with amphotropic properties. Analysis of tumor derived virus purified by limiting dilution techniques indicated that its interference and neutralization spectra were essentially identical to parental HIX virus and...

journal_title：Journal of virology

authors： Fischinger PJ,Dunlop NM,Blevins CS

更新日期：1978-05-01 00:00:00

abstract：:Swine influenza viruses (SIV) naturally infect pigs and can be transmitted to humans. In the pig, genetic reassortment to create novel influenza subtypes by mixing avian, human, and swine influenza viruses is possible. An SIV vaccine inducing cross-protective immunity between different subtypes and strains circulating...

journal_title：Journal of virology

authors： Richt JA,Lekcharoensuk P,Lager KM,Vincent AL,Loiacono CM,Janke BH,Wu WH,Yoon KJ,Webby RJ,Solórzano A,García-Sastre A

更新日期：2006-11-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) has evolved multiple strategies for suppression of the antiviral response of the infected cell. DNA array technology has revealed that HCMV clearly regulates host gene expression during the course of a productive infection by enhancing, sustaining, or suppressing steady-state levels of cel...

journal_title：Journal of virology

authors： Gealy C,Denson M,Humphreys C,McSharry B,Wilkinson G,Caswell R

更新日期：2005-01-01 00:00:00

abstract：:We have obtained a polyclonal antiserum, N-BE, against the denatured, amino-terminal half of the measles virus (MV) nucleocapsid (N) protein and a monoclonal antibody (MAb), N46, which recognizes a conformation-dependent epitope in the same region. Amino acid residues 23 to 239 were required and sufficient for the for...

journal_title：Journal of virology

authors： Gombart AF,Hirano A,Wong TC

更新日期：1993-07-01 00:00:00

abstract：:The murine polyomavirus (Py) enters mouse fibroblasts and kidney epithelial cells via an endocytic pathway that is caveola-independent (as well as clathrin-independent). In contrast, uptake of simian virus 40 into the same cells is dependent on caveola. Following the initial uptake of Py, both microtubules and microfi...

journal_title：Journal of virology

authors： Gilbert JM,Goldberg IG,Benjamin TL

更新日期：2003-02-01 00:00:00

abstract：:Transient transfection experiments indicated (i) that E6 protein of non-cancer-associated cutaneous human papillomavirus type 1 (HPV-1) can inhibit p53-mediated transcriptional transactivation in both p53-deficient human cells (H358) and normal rat cells (3Y1), but those of cancer-associated cutaneous HPV-5, -8, and -...

journal_title：Journal of virology

authors： Kiyono T,Hiraiwa A,Ishii S,Takahashi T,Ishibashi M

更新日期：1994-07-01 00:00:00

abstract：:Broadly neutralizing antibodies (bnAbs) can prevent lentiviral infection in nonhuman primates and may slow the spread of human immunodeficiency virus type 1 (HIV-1). Although protection by passive transfer of human bnAbs has been demonstrated in monkeys, durable expression is essential for its broader use in humans. G...

journal_title：Journal of virology

authors： Saunders KO,Wang L,Joyce MG,Yang ZY,Balazs AB,Cheng C,Ko SY,Kong WP,Rudicell RS,Georgiev IS,Duan L,Foulds KE,Donaldson M,Xu L,Schmidt SD,Todd JP,Baltimore D,Roederer M,Haase AT,Kwong PD,Rao SS,Mascola JR,Nabel

更新日期：2015-08-01 00:00:00

abstract：:We provide here new insights into rotavirus (RRV) pathogenicity by showing that RRV infection promotes structural and functional injuries localized at the tight junctions (TJ) in the cell-cell junctional complex of cultured polarized human intestinal Caco-2 cells forming monolayers. RRV infection resulted in a progres...

journal_title：Journal of virology

authors： Obert G,Peiffer I,Servin AL

更新日期：2000-05-01 00:00:00

abstract：:The release of the ribonucleic acid (RNA)-containing phage MS2 from Escherichia coli is accompanied by cellular lysis at 37 C, whereas at 30 C phage are released from intact cells. Chloramphenicol or rifampin prevents the release of progeny phage particles at both temperatures. Neither drug causes an immediate cessati...

journal_title：Journal of virology

authors： Engelberg H,Soudry E

更新日期：1971-09-01 00:00:00