Abstract：
:Tissue specificity of cell adhesion was directly characterized in a unit cell interaction using a novel laser trapping cell manipulator in combination with a fixed micropipet. We quantified the adhesive specificity of endodermal and ectodermal epithelial cells from Hydra, which are known to sort out within hours after being dissociated and then randomly reaggregate. It was shown that homotypic pairs of cells from the same tissue source could adhere to each other within a certain period, while heterotypic pairs could not form an adhesion. It was also found that the adhesion probability was higher in endodermal epithelial cell pairs than in ectodermal epithelial cell pairs. The former pairs could adhere with a contact period of less than 30 sec, while 60% of the latter remained nonadherent even after a 6-min forced contact. The adhesive strength of the latter was estimated to be as large as 30 pN, while that of the former was much larger than 50 pN. The tissue-specific adhesivity quantitatively measured provides a new insight into the mechanism of cell sorting.
journal_name
Dev Bioljournal_title
Developmental biologyauthors
Sato-Maeda M,Uchida M,Graner F,Tashiro Hdoi
10.1006/dbio.1994.1068subject
Has Abstractpub_date
1994-03-01 00:00:00pages
77-84issue
1eissn
0012-1606issn
1095-564Xpii
S0012-1606(84)71068-2journal_volume
162pub_type
杂志文章abstract：:In medusae of the hydrozoan Cytaeis uchidae, oocyte meiotic maturation and spawning occur as a consequence of dark-light transition. In this study, we investigated the mechanism underlying the initiation of meiotic maturation using in vitro (isolated oocytes from ovaries) and in vivo (ovarian oocytes in medusae) syste...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2006.06.034
更新日期：2006-10-01 00:00:00
abstract：:In the ascidian Ciona intestinalis, oral siphon amputation activates adult stem cell niches in the branchial sac to divide and dispatch migratory progenitor cells to a regeneration blastema at the site of injury. This study shows that progenitor cells derived from branchial sac stem cell niches have roles in homeostas...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2018.09.005
更新日期：2019-04-15 00:00:00
abstract：:In ascidian embryos, the earliest transcription from the zygotic genome begins between the 8-cell and 16-cell stages. Gata.a, a maternally expressed Gata transcription factor, activates target genes specifically in the animal hemisphere, whereas the complex of β-catenin and Tcf7 antagonizes the activity of Gata.a and ...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2019.11.009
更新日期：2020-02-15 00:00:00
abstract：:Sensory placodes are unique columnar epithelia with neurogenic potential that develop in the vertebrate head ectoderm next to the neural tube. They contribute to the paired sensory organs and the cranial sensory ganglia generating a wide variety of cell types ranging from lens fibres to sensory receptor cells and neur...
journal_title：Developmental biology
pub_type： 杂志文章,评审
doi：10.1016/j.ydbio.2004.08.037
更新日期：2004-12-01 00:00:00
abstract：:We have examined the presence of protein kinase C in oocytes of Chaetopterus pergamentaceus and its role in the initiation of germinal vesicle breakdown (GVBD). First, we demonstrated that the oocytes contain a phospholipid- and calcium-dependent protein kinase, protein kinase C (PKC). Since PKC is the primary intrace...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(92)90294-q
更新日期：1992-02-01 00:00:00
abstract：:Developmental boundaries ensure that cells fated to participate in a particular structure are brought together or maintained at the appropriate locale within developing embryos. Parasegment grooves mark the position of boundaries that separate every segment of the Drosophila embryo into anterior and posterior compartm...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2008.04.026
更新日期：2008-09-15 00:00:00
abstract：:Replication-dependent histone genes in the mouse and Xenopus share a common regulatory element within the protein-encoding sequence called the CRAS alpha element (coding region activating sequence alpha) which has been shown to mediate normal expression in vivo and to interact with nuclear factors in vitro in a cell c...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1996.8459
更新日期：1997-02-01 00:00:00
abstract：:Mutations in the Bone Morphogenetic Protein (BMP) pathway are associated with a range of defects in skeletal formation. Genetic analysis of BMP signaling requirements is complicated by the presence of three partially redundant BMPs that are required for multiple stages of limb development. We generated an inducible al...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2014.07.003
更新日期：2014-09-15 00:00:00
abstract：:The embryonic cell lineage of Caenorhabditis elegans has been traced from zygote to newly hatched larva, with the result that the entire cell lineage of this organism is now known. During embryogenesis 671 cells are generated; in the hermaphrodite 113 of these (in the male 111) undergo programmed death and the remaind...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(83)90201-4
更新日期：1983-11-01 00:00:00
abstract：:Hippo (Hpo) signaling plays a critical role in restricting tissue growth and organ size in both invertebrate and vertebrate animals. However, how the Hpo kinase is regulated during development has not been clearly understood. Using a Bimolecular Fluorescence Complementation assay, we have investigated the functional s...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2012.12.017
更新日期：2013-03-15 00:00:00
abstract：:Arthropods, vertebrates, and annelids all have a segmented body. Our recent discovery of involvement of Notch-signalling in spider segmentation revived the discussion on the origin of segmented body plans and suggests the sharing of a common genetic program in a common ancestor. Here, we analysed the spider homologues...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2005.01.024
更新日期：2005-04-01 00:00:00
abstract：:Specific binding of spermatozoa to the zona pellucida that surrounds mammalian eggs is a key step in the fertilization process. However, the sperm proteins that recognise zona pellucida receptors remain contentious despite longstanding research efforts to identify them. Here we present evidence that proacrosin, a tiss...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2007.04.001
更新日期：2007-06-15 00:00:00
abstract：:During the development of locomotion circuits it is essential that motoneurons with distinct subtype identities select the correct trajectories and target muscles. In vertebrates, the generation of motoneurons and myelinating glia depends on Olig2, one of the five Olig family bHLH transcription factors. We investigate...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2012.06.027
更新日期：2012-09-15 00:00:00
abstract：:The forkhead genes encode a transcription factor involved in embryogenesis and pattern formation in multicellular organisms. They are mammalian transcriptional regulators that bind DNA as a monomer through their forkhead domain. The Foxf2 (LUN) mRNA is expressed in the mesenchyme directly adjacent to the ectoderm-deri...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/s0012-1606(03)00176-3
更新日期：2003-07-01 00:00:00
abstract：:During heart formation, the heart grows and undergoes dramatic morphogenesis to achieve efficient embryonic function. Both in fish and amniotes, much of the growth occurring after initial heart tube formation arises from second heart field (SHF)-derived progenitor cell addition to the arterial pole, allowing chamber f...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2020.11.008
更新日期：2021-02-01 00:00:00
abstract：:G protein Galpha subunits contribute to the specificity of different signal transduction pathways in Dictyostelium discoideum but Galpha subunit-effector interactions have not been previously identified. The requirement of the Dictyostelium Galpha4 subunit for MAP kinase (MAPK) activation and the identification of a p...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2009.09.011
更新日期：2009-11-15 00:00:00
abstract：:Three-dimensional (3D) organoid models derived from human pluripotent stem cells provide a platform for studying human development and understanding disease mechanisms. Most studies that examine biallelic inactivation of the cell cycle regulator Retinoblastoma 1 (RB1) and the link to retinoblastoma is in mice, however...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2020.03.011
更新日期：2020-06-15 00:00:00
abstract：:Leaf primordia, first visible as small bumps, are produced in a cyclical pattern at the edges of the shoot apex, a smooth region at the top of the stem. Their formation is a biomechanical process. This review first considers hypothetical construction mechanisms and then summarizes research that provides information ab...
journal_title：Developmental biology
pub_type： 杂志文章,评审
doi：10.1016/0012-1606(92)90089-y
更新日期：1992-09-01 00:00:00
abstract：:Macronuclei of Tetrahymena thermophila contain a typical H1 which has been shown to be missing from micronuclei. Instead, micronuclei contain three unique polypeptides, alpha, beta, and gamma, which are associated with linker regions of micronuclear chromatin. In this report polyclonal antibodies raised against macron...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(85)90339-2
更新日期：1985-05-01 00:00:00
abstract：:Germ line transformation has been used to map the cis regulatory DNA elements responsible for the precise and evolutionarily stable developmental expression of the s18 chorion gene. Constructs containing chimeric combinations of Drosophila melanogaster and D. grimshawi DNA regions, as well as D. grimshawi sequences al...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(92)90160-i
更新日期：1992-07-01 00:00:00
abstract：:The murine allantois will become the umbilical artery and vein of the chorioallantoic placenta. In previous studies, growth and differentiation of the allantois had been elucidated in whole embryos. In this study, the extent to which explanted allantoises grow and differentiate outside of the conceptus was investigate...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.2001.0227
更新日期：2001-05-15 00:00:00
abstract：:Retinal ganglion cells (RGCs) are the first cell type to differentiate during retinal histogenesis. It has been postulated that specified RGCs subsequently influence the number and fate of the remaining progenitors to produce the rest of the retinal cell types. However, several genetic knockout models have argued agai...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2008.01.015
更新日期：2008-04-15 00:00:00
abstract：:Vertebrate retinal progenitor cells (RPCs) undergo a robust proliferative expansion to produce enough cells for the retina to form appropriately. Vsx2 (formerly Chx10), a homeodomain protein expressed in RPCs, is required for sufficient proliferation to occur. Sonic Hedgehog protein (SHH), secreted by retinal ganglion...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2008.02.055
更新日期：2008-05-15 00:00:00
abstract：:Skeletal muscles of the avian limb are derived from mononucleated myogenic precursor cells (myoblasts) that migrate into the somatopleural mesoderm of the developing limb bud from the ventrolateral dermomyotome of limb adjacent somites. In the present study, we utilized replication-deficient lacZ-encoding retroviruses...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/s0012-1606(02)00028-3
更新日期：2003-01-15 00:00:00
abstract：:The transition from maternal to zygotic gene expression in the mouse occurs in the 2-cell embryo. Previous studies in which DNA was injected into 2-cell embryos revealed that transcription promoters and origins of DNA replication are strongly repressed in cleavage stage embryos unless linked to an embryo-responsive en...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1995.1160
更新日期：1995-06-01 00:00:00
abstract：:The effect of hydrocortisone on the development of dorsal skin was analyzed in the chick embryo by (1) transmission electron microscopy, (2) indirect immunofluorescence histology of extracellular matrix components (collagen types I, III, and IV; fibronectin; and laminin), and (3) quantitative determination of collagen...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(84)90056-3
更新日期：1984-11-01 00:00:00
abstract：:A functional ribosomal protein mRNA, encoding the 60 S subunit protein L1, has been synthesized in vitro using bacteriophage SP6 RNA polymerase. This mRNA directs the synthesis of a product indistinguishable from L1 protein purified from Xenopus ovarian ribosomes. Our results show that L1 synthesis in stage VI oocytes...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(88)90247-3
更新日期：1988-03-01 00:00:00
abstract：:TGF-beta superfamily members signal through a heteromeric receptor complex to regulate craniofacial development. TGF-beta type II receptor appears to bind only TGF-beta, whereas TGF-beta type I receptor (ALK5) also binds to ligands in addition to TGF-beta. Our previous work has shown that conditional inactivation of T...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2008.03.045
更新日期：2008-08-01 00:00:00
abstract：:The individual blastomeres of the preimplantation mouse embryo become polarized during the 8-cell stage. Microvilli become restricted to the free surface of the embryo and this region of the membrane shows increased labeling with FITC-Con A and trinitrobenzenesulfonate (TNBS). Previous studies have shown that this pol...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(86)90204-6
更新日期：1986-04-01 00:00:00
abstract：:Concentration of mast-cell precursors in hematopoietic tissues of mouse embryos was evaluated by a limiting dilution method. Cells from yolk sacs, livers, and bodies of (WB x C57BL/6)F1 (hereafter called WBB6F1)- +/+ embryos were injected directly into the skin of adult WBB6F1-W/Wv mice which were genetically depleted...
journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(83)90066-0
更新日期：1983-05-01 00:00:00
