The effect of p38 mitogen-activated protein kinase on mucin gene expression and apoptosis in Helicobacter pylori-infected gastric epithelial cells.

abstract：:There are multiple lines of compelling evidence supporting the beneficial effect of exercise on the prevention and/or improvement of certain chronic diseases. However, exhaustive or intense exercise causes oxygen free radical generation and oxidative stress, which can lead to injuries and chronic fatigue as well as in...

journal_title：Annals of the New York Academy of Sciences

authors： Kim SY,Jun TW,Lee YS,Na HK,Surh YJ,Song W

更新日期：2009-08-01 00:00:00

abstract：:Regulation of pulmonary oxygen uptake (VO2p) during exercise depends on cellular energy demand, blood flow, ventilation, oxygen exchange across membranes, and oxygen utilization in the contracting skeletal muscle. In human and animal studies of metabolic processes that control cellular respiration in working skeletal ...

journal_title：Annals of the New York Academy of Sciences

authors： Zhou H,Lai N,Saidel GM,Cabrera ME

更新日期：2008-03-01 00:00:00

abstract：:Basal phagocytosis of neutrophils, a crucial component of non-specific immunity, is an eminently circadian parameter. In mice and rats, rates of phagocytosis peak in the second half of the dark span. A lipopolysaccharide-induced phagocytic response challenged in this period appears the most significant in amplitude an...

journal_title：Annals of the New York Academy of Sciences

authors： Hriscu ML

更新日期：2005-12-01 00:00:00

abstract：:Our objective was to learn the prevalence of spotted fever group (SFG) Rickettsia detected in ticks in La Rioja, in the north of Spain. From 2001 to 2005, 496 ticks representing 7 tick species were analysed at the Hospital de La Rioja. Ticks were removed from humans with or without rickettsial syndrome (n = 59) or col...

journal_title：Annals of the New York Academy of Sciences

authors： Oteo JA,Portillo A,Santibáñez S,Pérez-Martínez L,Blanco JR,Jiménez S,Ibarra V,Pérez-Palacios A,Sanz M

更新日期：2006-10-01 00:00:00

abstract：:The striatum is the major input nucleus of the basal ganglia. It is thought to play a key role in learning on the basis of positive reinforcement and in action selection. One view of the striatum conceives it as comprising a reiterated matrix of processing units that perform common operations in different striatal reg...

journal_title：Annals of the New York Academy of Sciences

authors： Wickens JR,Budd CS,Hyland BI,Arbuthnott GW

更新日期：2007-05-01 00:00:00

abstract：:Primary hyperparathyroidism (PHPT) results from excessive secretion of parathyroid hormone (PTH), and catabolic and anabolic effects of PTH on bone may lead to overall deleterious effects on skeleton. The aim of this study was to analyze the changes in lumbar spine bone mineral density (BMD) in patients with PHPT who ...

journal_title：Annals of the New York Academy of Sciences

authors： Lumachi F,Camozzi V,Ermani M,Nardi A,Luisetto G

更新日期：2007-11-01 00:00:00

abstract：:The Na,K-ATPase gamma subunit is present primarily in kidney as two splice variants, gammaa and gammab, which differ only at their extracellular N-termini. Two distinct effects of gamma are seen in biochemical Na,K-ATPase assays of mammalian (HeLa) cells transfected with gammaa or gammab, namely, (i) a decrease in K'(...

journal_title：Annals of the New York Academy of Sciences

authors： Blostein R,Pu HX,Scanzano R,Zouzoulas A

更新日期：2003-04-01 00:00:00

abstract：:Anaplasma phagocytophilum (A. phagocytophilum, formerly Ehrlichia phagocytophila) is a tick-borne pathogen responsible for tick-borne fever in ruminants, equine granulocytic ehrlichiosis (EGE) in horses, canine granulocytic ehrlichiosis (CGE) in dogs, and for human granulocytic ehrlichiosis (HGE). Human cases have bee...

journal_title：Annals of the New York Academy of Sciences

authors： Alberti A,Sparagano OA

更新日期：2006-10-01 00:00:00

abstract：:Deposition of amyloid beta protein in the brain is the major pathological feature of Alzheimer's disease. Amyloid beta protein is generated from beta-amyloid precursor protein by beta-secretase and gamma-secretase. Proteolytic processing of amyloid precursor protein at the beta site by BACE1 is essential to generate a...

journal_title：Annals of the New York Academy of Sciences

authors： Zhou W,Qing H,Tong Y,Song W

更新日期：2004-12-01 00:00:00

abstract：:Stabilization of images on the fovea during either fore/aft translation of a subject or fore/aft movement of a visual target in front of a stationary observer imposes complex geometrical requirements that depend upon the eccentricity of the object of interest with respect to the eyes. Each eye needs to be rotated inde...

journal_title：Annals of the New York Academy of Sciences

authors： Ramat S,Zee DS

更新日期：2005-04-01 00:00:00

abstract：:Carbonic anhydrase is abundantly distributed in renal tissue and functions, as in other epithelia, to catalyze the hydration-dehydration reaction of CO2. The proximal tubule is responsible for at least 80% of whole kidney bicarbonate transport and is mediated by proton secretion. Membrane-bound carbonic anhydrase appe...

journal_title：Annals of the New York Academy of Sciences

authors： DuBose TD Jr

更新日期：1984-01-01 00:00:00

abstract：:In the present study, we examined the potential impact of a T-to-C substitution at nucleotide 1519 of the GABA(A)alpha6 receptor subunit gene (GABRA6) on obesity and obesity-related phenotypes as well as circulating hormones, including salivary cortisol, in 284 unrelated Swedish men born in 1944. The subjects were gen...

journal_title：Annals of the New York Academy of Sciences

authors： Rosmond R,Bouchard C,Björntorp P

更新日期：2002-06-01 00:00:00

abstract：:The primate orbitofrontal cortex (OFC) is often treated as a single entity, but architectonic and connectional neuroanatomy indicate that it has distinguishable parts. Nevertheless, few studies have attempted to dissociate the functions of its subregions. Here we review findings from recent neuropsychological and neur...

journal_title：Annals of the New York Academy of Sciences

authors： Rudebeck PH,Murray EA

更新日期：2011-12-01 00:00:00

abstract：:We compared 10 episodes (8 patients) of Q fever endocarditis with 27 episodes (27 patients) of native valve endocarditis. Patients with Q fever endocarditis were more likely to have weight loss (p less than 0.003), experience fatigue (p less than 0.07), have clubbing of the fingers (p less than 0.005), have a diastoli...

journal_title：Annals of the New York Academy of Sciences

authors： Marrie TJ

更新日期：1990-01-01 00:00:00

abstract：:The Mediterranean diet is now recognized as being both limited in toxicity and abundant in nutrient and non-nutrient protective factors. A large body of basic, clinical and epidemiological studies have been developed in recent years to provide evidence of the benefits of the Mediterranean diet or its components on hea...

journal_title：Annals of the New York Academy of Sciences

authors： Covas MI,Marrugat J,Fitó M,Elosua R,de la Torre-Boronat C

更新日期：2002-05-01 00:00:00

abstract：:GEM 231 is a second-generation antisense oligonucleotide targeted against the RIalpha regulatory subunit of cAMP-dependent protein kinase type I (PKA-I). Excessive expression of PKA-I is associated with cell proliferation and transformation, and increased levels of secreted extracellular PKA (ECPKA) are found in the s...

journal_title：Annals of the New York Academy of Sciences

authors： Mani S,Goel S,Nesterova M,Martin RM,Grindel JM,Rothenberg ML,Zhang R,Tortora G,Cho-Chung YS

更新日期：2003-12-01 00:00:00

abstract：:Large quantities of polybrominated diphenyl ethers (PBDEs) have been used as flame retardants in clothing and plastic products since the 1970s. A small fraction of the PBDEs in manufactured products subsequently enters municipal wastewater. Nevertheless, the resistance of these compounds to chemical and biochemical tr...

journal_title：Annals of the New York Academy of Sciences

authors： Arnold RG,Teske S,Tomanek M,Engstrom J,Leung C,Zhang J,Banihani Q,Quanrud D,Ela WP,Sáez AE

更新日期：2008-10-01 00:00:00

abstract：:Various hypotheses on the origin of cerebellar downbeat nystagmus (DBN) have been presented; the exact pathomechanism, however, is still not known. Based on previous anatomical and electrophysiological studies, we propose that an asymmetry in the distribution of on-directions of vertical gaze-velocity Purkinje cells l...

journal_title：Annals of the New York Academy of Sciences

authors： Marti S,Straumann D,Glasauer S

更新日期：2005-04-01 00:00:00

abstract：:Natural systems cannot be closed to the environment. At the same time there is a necessity for closure in order to build the system. It is this quint-essential tension between openness and closure that drives systems to unfold into further stages or levels of growth and development. In other words, the emergence of or...

journal_title：Annals of the New York Academy of Sciences

authors： Alvarez De Lorenzana JM

更新日期：2000-01-01 00:00:00

abstract：:This article reviews research on the Finnish model of peer-group mentoring (PGM). The theoretical foundation of the model is based on the constructivist theory of learning, the concept of autonomy in teaching profession, peer learning, and narrative identity work. The model has been disseminated nationwide in the educ...

journal_title：Annals of the New York Academy of Sciences

authors： Tynjälä P,Pennanen M,Markkanen I,Heikkinen HLT

更新日期：2021-01-01 00:00:00

abstract：:Methamphetamine (METH) produces nigrostriatal dopamine (DA) loss, partly resembling that which occurs in Parkinson's disease (PD). In PD there is also a marked alteration in the gut. Given the similarities between the central DA denervation produced by METH and PD, in the present study we evaluated the alterations in ...

journal_title：Annals of the New York Academy of Sciences

authors： Natale G,Kastsiuchenka O,Pasquali L,Ruggieri S,Paparelli A,Fornai F

更新日期：2008-10-01 00:00:00

abstract：:Estrogen has clearly been shown to decrease bone loss and frequency of osteoporotic fractures. Calcitonin has been shown in several studies to reduce the rate of bone loss, although no data are yet available demonstrating a reduction in fracture frequency. Studies of osteoporosis intrinsically assume that prevention o...

journal_title：Annals of the New York Academy of Sciences

authors： Lindsay R,Cosman F

更新日期：1990-01-01 00:00:00

abstract：:It is known that red wines have antioxidant properties owing to the presence of polyphenols and hydroxycinnamates. It has been reported that these compounds are efficient scavengers of peroxynitrite (ONOO(-)). We assayed the ONOO(-)-scavenging activity of plant polyphenols, hydroxycinnamates, and red wines using a flu...

journal_title：Annals of the New York Academy of Sciences

authors： Valdez LB,Actis-Goretta L,Boveris A

更新日期：2002-05-01 00:00:00

abstract：:Achalasia is a primary motility disorder of the esophagus, and while there are several treatment options, there is no consensus regarding them. When therapeutic intervention for achalasia fails, a careful evaluation of the cause of the persistent or recurrent symptoms using upper endoscopy, esophageal manometry, and c...

journal_title：Annals of the New York Academy of Sciences

authors： Felix VN,Murayama KM,Bonavina L,Park MI

更新日期：2020-12-01 00:00:00

abstract：:Modern contraceptive methods represent more than a technical advance: they are the instrument of a true social revolution-the "first reproductive revolution" in the history of humanity, an achievement of the second part of the 20th century, when modern, effective methods became available. Today a great diversity of te...

journal_title：Annals of the New York Academy of Sciences

authors： Benagiano G,Bastianelli C,Farris M

更新日期：2006-12-01 00:00:00

abstract：:The same retinal image motion can be produced by a variety of combinations of eye and target motion. In natural conditions, extraretinal information disambiguates retinal information for motion perception. By controlling the timing of visual motion with respect to saccades, it was possible to appraise the roles for mo...

journal_title：Annals of the New York Academy of Sciences

authors： Lee C,Lee J

更新日期：2005-04-01 00:00:00

abstract：:[(18) F]Fluorodeoxyglucose (FDG) is a tracer for glucose metabolism. Its distribution is not specific to cancer cells but is also observed in inflammatory tissue, including macrophages, capillaries, and fibroblasts. Rheumatoid arthritis (RA) is a systemic, chronic inflammation of the joints resulting in synovitis. The...

journal_title：Annals of the New York Academy of Sciences

authors： Kubota K,Ito K,Morooka M,Minamimoto R,Miyata Y,Yamashita H,Takahashi Y,Mimori A

更新日期：2011-06-01 00:00:00

abstract：:Oxidative stress is a common response of epidermal cells to a variety of noxious stimuli such as ultraviolet (UV) radiation from solar light and proinflammatory cytokines from skin-infiltrating leukocytes. Here, we report that two types of plant-derived antioxidants, the phenylpropanoid glycoside verbascoside as well ...

journal_title：Annals of the New York Academy of Sciences

authors： Pastore S,Potapovich A,Kostyuk V,Mariani V,Lulli D,De Luca C,Korkina L

更新日期：2009-08-01 00:00:00

abstract：:The objective of this double-blind, placebo-controlled, dose-escalation study is to evaluate safety, tolerability, and enhancement on healing of thymosin beta-4 (Tbeta-4) administered topically in patients with venous ulcers. Three groups of patients, coming from 10 sites, 5 from Italy and 5 from Poland, will be enrol...

journal_title：Annals of the New York Academy of Sciences

authors： Guarnera G,DE Rosa A,Camerini R

更新日期：2007-09-01 00:00:00

abstract：:Transcriptional profiling and functional genomics experiments using E11.5 metanephros organ cultures from Ahr(-/-) and Ahr(+/+) have shown that aryl hydrocarbon receptor (AHR) transcription factor is involved in the regulation of mesenchymal-to-epithelial transition (MET) during nephrogenesis. This response is mediate...

journal_title：Annals of the New York Academy of Sciences

authors： Ramos KS

更新日期：2006-09-01 00:00:00