Abstract:
BACKGROUND:Treatment of wrinkles has become an increasing problem for dermatologists. Hyaluronic acid is a component of the family of glycosaminoglycans (GAGS, substances known for their property of retaining water), that significantly decreases with aging and in wrinkles. A new technique that uses a specific pulsed electromagnetic field, electrorydesis, has been introduced in the treatment of wrinkles associated with aging. The treatment is based on the reported in vitro effects of specific electromagnetic fields on fibroblast cultures (e.g., an increase in DNA synthesis and in the production of collagen and presumably also of GAGS). METHODS:The in vivo effects of the electromagnetic field on aged skin (3 subjects aged 50, 56 and 60 years), with particular focus on the ultrastructural modifications and GAGS amount before and after the treatment, were evaluated by electron microscope. RESULTS:The ultrastructural study (tissue stained with alcian blue) showed after treatment a significant increase (p < 0.005) of the electron-dense granules (corresponding to hyaluronic acid), located in collagen elastic fibers, and in the soluble matrix. This presumably leads to subsequent edema that was clinically evident after the treatment. CONCLUSIONS:These data suggest that the increased levels of GAGS and the subsequent edema of the dermis could explain at least in part the clinical changes observed after electrorydesis treatment (e.g., swelling and "disappearance" of the wrinkle).
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Ghersetich I,Teofoli P,Benci M,Lotti Tdoi
10.1111/j.1365-4362.1994.tb02933.xsubject
Has Abstractpub_date
1994-09-01 00:00:00pages
661-3issue
9eissn
0011-9059issn
1365-4632journal_volume
33pub_type
杂志文章abstract:BACKGROUND:The plantar surface is one of the commonest sites of malignant melanoma in the Japanese; however, the biological behavior is not sufficiently clarified, because of the paucity of long-term studies. We attempted an epidemiologic survey of the cases of plantar melanoma treated in our institute to study the sur...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.1999.00736.x
更新日期:1999-07-01 00:00:00
abstract::Puncta pruritica is a chronic condition of unknown cause that is characterized by the occurrence of one or more intensely itchy pinpoint spots in clinically normal skin. Four cases are reported here. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1991.tb02619.x
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:Self-reported complaints in people having tattoos, including swelling, itch, and photosensitivity, are frequent. Tattooists are usually heavily tattooed with multiple extended colored tattoos and constitute a specific population of interest. OBJECTIVES:To assess the prevalence of cutaneous complications on ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13030
更新日期:2016-07-01 00:00:00
abstract::In 107 cases of facial contact dermatitis, routine Finn chamber epicutaneous tests with TROLAB European Standard Allergens (ESAs) were performed. Sixty-one (57%) had positive reaction. The most frequent contact allergens were paraphenylenediamine dihydrochloride (16%), followed by fragrance mix (15%), and nickel sulfa...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1991.tb04867.x
更新日期:1991-07-01 00:00:00
abstract:BACKGROUND:Basal cell carcinoma (BCC) is the most common cutaneous malignancy in the white population and occurs infrequently in dark-pigmented individuals. Albinism is an established risk factor for skin cancer in black Africans. METHODS:We evaluated the clinical histories and treatment outcomes of patients with a hi...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2007.03272.x
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Plantar hyperhidrosis is a common illness with significant impact on quality of life. Oxybutynin presents good short-term results, but longer follow-up results are lacking. We evaluated oxybutynin effectiveness in patients who were not surgically treated and who had at least six months of follow-up. METHODS...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12729
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The relationships between androgenetic alopecia (AGA) and various factors related to metabolic syndrome have been demonstrated in previous studies. However, it remains unclear because of inconsistent results. We investigated the associations between AGA and various risk factors related to metabolic syndrome ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13843
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Dithranol is a potent reducing substance and is thought to achieve its effect on psoriasis by reduction of cell turnover. It was shown to be efficacious in adults, but its efficacy has not been documented in children. METHODS:The efficacy of short-contact therapy, a dithranol cream preparation, was retrospe...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1994.tb01005.x
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue-derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC-CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of a...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12650
更新日期:2015-06-01 00:00:00
abstract::Three heroin addicts had Candida folliculitis of the scalp, beard, and pubis associated with fever, chills, headache, and fatigue. In each case, pseudohyphae were found within a hair and yeasts around it and Candida was recovered from urine. These facts support a systemic dissemination. Since serious ocular and osteoa...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1986.tb04547.x
更新日期:1986-03-01 00:00:00
abstract:BACKGROUND:The majority of lasers used for hair removal target melanin as the chromophore. In contrast with other cutaneous applications of lasers, lasers used for hair removal must generate a limited, controlled degree of thermal damage to permanently remove hairs. AIM:To remove excess back hair from two male patient...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2001.01251.x
更新日期:2001-08-01 00:00:00
abstract::Healthy adult (New Zealand, Dutch Belt, and Wild) rabbits were infected with rabbit papilloma virus (Shope variety). The resultant papillomas were treated with salicylic acid in a new transdermal drug delivery system utilizing a karaya gum glycol matrix. Biopsy samples of treated papillomas were taken at 1, 2, and 3 w...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1988.tb02414.x
更新日期:1988-10-01 00:00:00
abstract:BACKGROUND:Potent teratogenicity limits the use of isotretinoin among females of childbearing potential (FCBP). OBJECTIVE:To explore the current practice of dermatologists for pregnancy prevention when prescribing isotretinoin for FCBP. MATERIALS AND METHODS:A self-administered questionnaire was distributed to 160 de...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.04875.x
更新日期:2011-09-01 00:00:00
abstract::Gardner-Diamond syndrome (GDS) is a rare psychodermatological condition characterized by the formation of spontaneous, painful skin lesions that develop into ecchymosis following episodes of severe physiological or psychological stress. The majority of GDS cases occur in young adult females, and although the etiology ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.14235
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Most cutaneous tuberculosis lesions contain few bacilli, so identification of Mycobacterium tuberculosis in conventional laboratory tests is difficult. In vitro amplification of specific DNA sequences using polymerase chain reaction (PCR) has become a valuable tool in the rapid detection of slow-growing orga...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2002.01604.x
更新日期:2002-12-01 00:00:00
abstract::The biology of wound healing is indeed a complex process. From phase 1 to phase 3, an orderly progression of events take place in the repair process. Various factors influence the rapidity and cosmetic appearance of this phenomenon. Physical, microbial, nutritional and environmental factors all have some role in the e...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4362.1975.tb00088.x
更新日期:1975-12-01 00:00:00
abstract::Methotrexate, the most common systemic small molecule used in the treatment of moderate to severe psoriasis, is associated with significant toxicities and adverse events. Long-term continuous usage is not recommended due to potential liver toxicity, myelosuppression, and other side effects. Abrupt cessation of methotr...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03419.x
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Herpes simplex virus (HSV) infections are usually chronically recurrent in the normal population and represent a significant cause of morbidity in immunocompromised patients. Acyclovir (ACV) is widely used for the treatment and prophylaxis of HSV infections. The emergence of ACV-resistant strains has been fr...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2007.03449.x
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Anthrax is a potentially fatal zoonotic disease. The diagnosis of cutaneous anthrax (CA) may be very difficult, particularly in atypical presentations and nonendemic regions. AIM:To evaluate the clinical features and diagnostic difficulties of 23 anthrax cases seen between May 2004 and September 2006. METH...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03665.x
更新日期:2008-10-01 00:00:00
abstract::Pruritus is among the most common complaints in the field of dermatology. It is also a disturbing symptom of many systemic disorders. Chronic pruritus (CP) refers to the cases of the symptom which last longer than 6 weeks. We conducted a prospective analysis of patients with generalized pruritus without primary skin l...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.14125
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:In July 2008, the German statutory health insurance introduced a nationwide skin cancer screening program. Before the introduction, eligible physicians had to qualify to perform the screening test and counsel their patients on skin cancer screening. To educate physicians, a curriculum and training materials ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13688
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Prurigo pigmentosa (PP), a rare inflammatory disease of the skin, is mostly reported in the ethnic Japanese population. Its pathogenesis remains unclear. The chronic and recurrent nature of PP implies a possible role of viral infection in the pathogenesis. The anti-inflammatory mechanism of doxycycline, whic...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2010.04625.x
更新日期:2011-01-01 00:00:00
abstract::The occurrence of erythema nodosum leprosum among leprosy patients treated with diamino diphenyl sulfone in an endemic area is not rare, unlike in the leprosy patients treated at Lagos University Teaching Hospital. Two Nigerian patients with this disease are described, in whom this rarity was seen. Recurrent monthly f...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1975.tb00160.x
更新日期:1975-11-01 00:00:00
abstract:OBJECTIVE:Although the etiology of Behcet's disease is not clarified yet, the vascular endothelial damage and thrombosis are prominent features of the disease. The underlying mechanisms of increased risk of thrombosis in Behcet's disease are not completely understood. It is stated that the changes in blood rheology suc...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2009.04229.x
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Surgery, in any setting, has several inherent risks not only to the patient, but the physician and his assistants as well. Safe handling and management of the sharps to prevent inoculation injuries is one of these risks, in particular: 1) instrument hand-off of the needle and needle driver between the physic...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03651.x
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Coccidiodomycosis is a systemic infection caused by Coccidioides immitis, a dimorphic fungus endemic in the south of the USA and the north of Mexico. The disease usually affects the lungs. Primary cutaneous infection is extremely rare. We present a report of a patient with primary cutaneous infection located...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4632.2004.02446.x
更新日期:2006-02-01 00:00:00
abstract::Like all organ systems, the skin undergoes significant changes during pregnancy. The majority of physiologic skin conditions related to gestation resolve after childbirth. However, they may cause significant concern or cosmetic distress or be mistaken for one of the specific dermatoses of pregnancy. Dermatoses unique ...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4632.2010.04869.x
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:An epidemic of cercarial dermatitis caused by Schistosoma spindale cercaria occurred in November 1988 in a district called Chaiya, Surajthani province, in Southern Thailand. CASE REPORTS:Fifty-eight Thai farmers in Chaiya, Surajthani gave a history of itch following immersion in water while planting rice. T...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1993.tb01448.x
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:Despite common endothelial origins, angiosarcoma and Kaposi's sarcoma are clinically and histologically distinct vascular proliferations. The development of angiosarcoma in a chronically edematous abdominal pannus is extremely uncommon. Similarly, tumors with the combined histologic features of angiosarcoma ...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4632.2004.02560.x
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:An allogeneic human skin graft is a temporary biologic dressing used in extensive burns that can be a providential treatment for affected patients. Skin quality depends directly on its microbial decontamination after processing in a tissue bank. Our objective was to describe the skin donor profiles in relati...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.14254
更新日期:2019-03-01 00:00:00