Abstract:
BACKGROUND:Dithranol is a potent reducing substance and is thought to achieve its effect on psoriasis by reduction of cell turnover. It was shown to be efficacious in adults, but its efficacy has not been documented in children. METHODS:The efficacy of short-contact therapy, a dithranol cream preparation, was retrospectively evaluated in 58 children with psoriasis. Dithranol cream (0.1-2%) was applied daily for 30 minutes to affected skin areas. Patients were evaluated at 1-4-week intervals. RESULTS:The median duration of therapy before the onset of remission was 2 months. Remission was achieved in 81% of the children. The median duration of remission was 4 months. Mild adverse skin reactions occurred in 20% of patients, but only one patient had to discontinue therapy. CONCLUSION:Short-contact therapy with dithranol cream preparation is an effective and well-tolerated treatment for childhood psoriasis. A thorough explanation of the disease and mode of therapy to patients and their parents is essential for good compliance and subsequent success.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Zvulunov A,Anisfeld A,Metzker Adoi
10.1111/j.1365-4362.1994.tb01005.xsubject
Has Abstractpub_date
1994-11-01 00:00:00pages
808-10issue
11eissn
0011-9059issn
1365-4632journal_volume
33pub_type
杂志文章abstract:BACKGROUND:Even with the widespread clinical use of cannabinoid receptor (CBR) stimulating compounds, such as palmitoylethanolamine, the role of CBR agonists on inflammatory skin diseases is not yet fully understood. This study was performed to investigate the effects of CBR agonists on skin inflammation, using acute a...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12841
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:The administration of interleukin-2 (IL-2) has recently been reported to be favorable for treating malignant hemangioendothelioma (MHE). METHODS:Two patients with MHE responded well to intralesional injections of recombinant IL-2 (rIL-2) without major side effects. The purpose of this study was to character...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1995.tb04406.x
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:Pemphigus herpetiformis (PH) is a rare subtype of pemphigus that presents challenges in diagnosis. OBJECTIVE:To review the presentation, diagnosis, and management of PH. METHODS:We reviewed the charts of all patients diagnosed and treated for PH in an immunobullous referral center between September 2007 an...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.12582
更新日期:2015-09-01 00:00:00
abstract::Dermatosis papulosa nigra (DPN) is a disorder commonly encountered in the adult black population. We describe 20 cases of clinicopathologically confirmed DPN cases treated with light abrasive curettage without local anesthesia. We found this procedure to be an effective therapy, which did not cause postoperative scarr...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1983.tb02131.x
更新日期:1983-12-01 00:00:00
abstract::Aquatic dermatoses encompass a broad spectrum of cutaneous injuries. These injuries may present through contact with invertebrate organisms such as jellyfish, sea urchins, corals, and molluscs. Each organism is equipped with a unique method of causing harm to man, therefore a myriad of presenting signs and symptoms sh...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4632.2011.05431.x
更新日期:2013-02-01 00:00:00
abstract::Pneumocystis jiroveci pneumonia is an opportunistic infection associated with substantial rates of mortality in immunosuppressed patients. Prophylaxis recommendations are mostly targeted toward patients with non-dermatologic diagnoses. This study was conducted to determine when dermatology patients treated with immuno...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.13231
更新日期:2016-08-01 00:00:00
abstract::Scars are problematic for thousands of patients. Scarring is a natural part of the healing process after an injury. However, the appearance of a scar and its treatment depend on multiple factors and on the experience of the therapist and the options available. Despite a plethora of rapidly evolving treatment options a...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13253
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:Whole-slide imaging with virtual microscopy is increasingly used as a tool in resident education and training, board certification and maintenance of certification examinations, and diagnostic evaluation. The objective of this study was to determine attitudes toward virtual microscopy compared with tradition...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12233
更新日期:2014-02-01 00:00:00
abstract::A 10-year-old immunocompetent boy presented with multiple, verrucous, disseminated pheohyphomycotic lesions caused by Exophiala spinifera. The patient was not responsive to combination antifungal therapy (itraconazole, terbinafine, fluconazole) and cryotherapy. As antifungal susceptibility is known to be variable for ...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4632.2007.03430.x
更新日期:2008-01-01 00:00:00
abstract::In a randomized, double-blind, parallel comparative study of 80 patients, impetigo and ecthyma were treated effectively by sulconazole nitrate 1% cream and miconazole nitrate 2% cream applied to lesions twice daily for 14 days. When treatment began, bacterial cultures from all pyodermal lesions yielded Group A beta-he...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-4362.1988.tb01273.x
更新日期:1988-12-01 00:00:00
abstract::The concentrations of zinc (Zn), copper (Cu), and iron (Fe) in the skin have been noninvasively determined in vivo by diagnostic x-ray spectrometry. The skin of healthy controls was divided into two major groups based upon the distribution of the concentrations of these elements. In the face and upper neck, the follow...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1986.tb03449.x
更新日期:1986-09-01 00:00:00
abstract::Cutaneous calcium deposition can occur in long-term inflammation. The deposition of calcium in long-standing acne may produce either small pigmented nodules or no visible lesions. The former type is or no visible lesions. The former type is much less common, with the nodules containing particulate spheres of mineral w...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1977.tb01897.x
更新日期:1977-11-01 00:00:00
abstract::Topical drugs can be absorbed percutaneously in sufficient amounts to cause untoward systemic effects. Generally speaking, infants and young children appears to be more vulnerable than adults. It has been shown that the prolonged and extensive use of topical corticosteroids can induce iatrogenic hypercorticism and tha...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1978.tb05977.x
更新日期:1978-12-01 00:00:00
abstract::There is some debate regarding the risk of developing malignancy and progression of malignancy in patients with psoriasis treated with biologics. The lack of extensive, long-term, and large studies, including patients with psoriasis, to assess these aforementioned risks makes it difficult to ascertain the safety profi...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.13129
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Targeted therapies and immunotherapies are increasingly prescribed, but classic chemotherapy agents are still highly used in cancer treatment. Both therapies, the old and the new, are associated with cutaneous adverse events (CAEs) that can cause treatment interruptions or reduce the quality of life of patie...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.15081
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:The clinical morphology of anogenital warts may vary from flat, filiform, papular, or verrucous to giant condyloma acuminatum. Clinically atypical-looking genital warts may alarm the clinician because of their suspected malignant potential, which may cause anxiety, often leading to aggressive interventions. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13711
更新日期:2017-10-01 00:00:00
abstract::Trimethylpsoralen, psoralen and 8-methoxypsoralen were adminstered in 10 mg dosage orally to 37, 29 and 23 patients with vitiligo. Complete improvement was noted in 8.9% and partial improvement was recorded in 59.5%. The overall results produced by trimethylpsoralen and psoralen were superior to those of 8-methoxyps...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/ijd.1975.14.3.205
更新日期:1975-04-01 00:00:00
abstract::Affecting approximately 9.4% of the population worldwide, acne vulgaris is a common chronic inflammatory skin disease. Medical students are exposed to higher levels of stress and have a higher prevalence of acne. However, the risk factors and the impact of acne on medical students' mental health remains poorly underst...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.15280
更新日期:2020-10-31 00:00:00
abstract::To date, various treatment modalities have failed to produce consistent improvement in patients having Behçet's disease. Recent reports in the literature, however, have shown promising results with the use of colchicine. Our patient, an 18-year-old white woman, satisfied the 1977 Istanbul Conference criteria for Behçe...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1982.tb01202.x
更新日期:1982-11-01 00:00:00
abstract::Fifty-seven patients with primary localized cutaneous amyloidosis (PLCA) were clinically and histopathologically reviewed. Two-thirds of patients had macular amyloidosis (MA). Intermediate cases having macular lesions with micropapules and/or lichens were identified. A spectrum for the disease is proposed, in which th...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1992.tb03245.x
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:Treatment of wrinkles has become an increasing problem for dermatologists. Hyaluronic acid is a component of the family of glycosaminoglycans (GAGS, substances known for their property of retaining water), that significantly decreases with aging and in wrinkles. A new technique that uses a specific pulsed el...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1994.tb02933.x
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:Venous ulcer is the most serious consequence of chronic venous insufficiency and is responsible for almost 70% of chronic leg ulcers. The main purpose of this research was to describe social, demographic and clinical characteristics of patients with venous ulcers and to identify some professional repercussio...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02276.x
更新日期:2005-12-01 00:00:00
abstract::The auricle is a flexible structure because it is formed by elastic cartilage. In the rare occurrence of ectopic auricular ossification, however, the cartilage is replaced by lamellar bone and becomes petrified. Such unphysiological replacement has been reported in association with local trauma, inflammation, systemic...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2007.03512.x
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Postherpetic neuralgia, a common sequele to herpes zoster infection, is a chronic debilitating problem. The available therapeutic modalities are usually ineffective. METHODS:A total of 3960 patients (1326 women and 2634 men; age group, 21-84 years), with postherpetic neuralgia as the presenting complaint an...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
doi:10.1046/j.1365-4362.1998.00392.x
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Sun exposure, light skin pigmentation, and melanocortin 1 receptor (MC1R) gene variants are independent risk factors for skin cancer. The Canary Islands have a sunny and temperate climate, but data regarding the phenotypic and genotypic risk factors among the population are lacking. METHODS:The main phenoty...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03680.x
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Selective depletion of CD4+ T lymphocytes is common in both primary and secondary immunodeficiencies. Idiopathic CD4+ T lymphocytopenia (ICL) cases are defined as a persistent CD4+ T lymphocyte count of less than 300x10(6) cells/L and/or less than 20% of the total T-cell count. METHOD:A 40-year-old woman, w...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.1999.00364.x
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:Patterns of skin disease in developing nations are changing as frequencies of non-communicable diseases continue to increase. Appraisal of the current status of the disease profile is of utmost importance for health planning and resource allocation. METHODS:A prospective analysis of 895 cases of outpatient ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12693
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:In July 2008, the German statutory health insurance introduced a nationwide skin cancer screening program. Before the introduction, eligible physicians had to qualify to perform the screening test and counsel their patients on skin cancer screening. To educate physicians, a curriculum and training materials ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13688
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Rosacea is a common, chronic dermatosis that requires long-term therapy. Oral isotretinoin and topical and/or oral antibiotics are effective, but their usage may be limited due to side-effects. OBJECTIVE:The goal of the study was to compare the efficacy of topical adapalene gel (0.1%) and topical metronidaz...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-4632.2004.02130.x
更新日期:2005-03-01 00:00:00
abstract::A 60-year-old man presented to the Emergency Department (ED) with large, painful, indurated plaques on the right thigh, left abdomen, left chest, and right chest, which began without any preceding trauma on the right thigh 3 weeks prior to presentation in the ED. He was initially treated with cefazolin 1 g three times...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2006.03067.x
更新日期:2007-10-01 00:00:00