Abstract:
BACKGROUND:Selective depletion of CD4+ T lymphocytes is common in both primary and secondary immunodeficiencies. Idiopathic CD4+ T lymphocytopenia (ICL) cases are defined as a persistent CD4+ T lymphocyte count of less than 300x10(6) cells/L and/or less than 20% of the total T-cell count. METHOD:A 40-year-old woman, with a history of psoriasis and paracetamol allergy, presented with persistent warts of the hands and condylomas of the ano-genitalia. Histological and virological analysis was carried out on genital and cutaneous lesions and peripheral blood. RESULTS:Serology for HIV-1, HIV-2, Epstein-Barr virus and parvovirus B19 were negative. There was lymphopenia of 10% CD4+ cells, with normal numbers of total leukocytes; there were no other-abnormal immunological findings. DNA analysis of cutaneous lesions revealed HPV-49 and HPV-3 in the hands and HPV-6 in the genital region. CONCLUSIONS:The cause of the ICL in this patient is unknown. HPV is not known to be an immunosuppressive agent; it remains to be determined whether the HPV-associated lesions are the cause or the result of immunosuppression.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Manchado Lopez P,Ruiz de Morales JM,Ruiz González I,Rodriguez Prieto MAdoi
10.1046/j.1365-4362.1999.00364.xsubject
Has Abstractpub_date
1999-02-01 00:00:00pages
119-21issue
2eissn
0011-9059issn
1365-4632journal_volume
38pub_type
杂志文章abstract:BACKGROUND:This study sought to gain a better understanding of the patient population in Kampala and was further designed to elucidate barriers that may delay individuals from receiving proper dermatologic care. METHODS:The study took place at the dermatovenereology clinic of a tertiary care hospital in Kampala. New a...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13435
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Sunbathing on the beach is one of the main risks for skin cancer. OBJECTIVE:In the summer of 2010, a skin cancer prevention campaign aimed at beachgoers was undertaken on the western Costa del Sol (southern Spain). METHODS:The campaign took place on beaches during July and August. A multicomponent interven...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12389
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Papulonecrotic tuberculid is a rarely reported cutaneous reaction to the mycobacterium bacillus. It is most often encountered in association with tuberculosis. The clinical and histologic picture of the entity is a distinctive one, but the etiology of the disease process is uncertain. Therapy directed agains...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1994.tb01537.x
更新日期:1994-02-01 00:00:00
abstract:BACKGROUND:Dengue infection is emerging as a public health problem in India. Despite numerous studies, there is a paucity of literature regarding the cutaneous manifestations of dengue. This study was performed to investigate the prevalence and type of cutaneous manifestations in dengue viral infection. METHODS:Two hu...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2007.03298.x
更新日期:2007-07-01 00:00:00
abstract::Telangiectasia macularis eruptiva perstans (TMEP) is a cutaneous form of mastocytosis. It has been rarely associated with an underlying myeloproliferative disorder. We report the case of a patient, while receiving treatment for thrombocytosis, with both platelet production and function inhibitors presented with TMEP. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02249.x
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Intralesional bleomycin is effective for the treatment of various dermatologic conditions. However, the efficacy of intralesional bleomycin for the treatment of corns has not been established. METHODS:A total of 50 patients with plantar corns were recruited and equally divided between groups A and B. Groups...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12586
更新日期:2014-12-01 00:00:00
abstract::Previous reports have shown that alterations in cutaneous and plasmatic fibrinolytic activity are found in cutaneous necrotizing vasculitis (CNV). In a combined investigation with direct immunofluorescence and autohistographic evaluation of tissue fibrinolytic activity in the lesional skin of 20 subjects affected by S...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1983.tb03323.x
更新日期:1983-03-01 00:00:00
abstract:BACKGROUND:Exposure to sunlight is an important etiologic factor in cutaneous melanoma (CM). In several countries, more cases of CM are diagnosed in summer than in winter. AIM:To analyze whether there is seasonal variation in the diagnosis of CM in southern Brazil. METHODS:Data were collected from a hospital-based re...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2009.04174.x
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:The purpose of the study was to examine the eggs of pubic lice with consideration of their clinical relevance. STUDY DESIGN:Pubic lice eggs were examined by scanning electron microscopy (SEM). RESULTS:The egg is totally encased by a proteinaceous sheath, except for the operculum, by which oxygen exchange oc...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2000.00901.x
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:Sarcoidosis is a chronic granulomatous disease of unknown etiology. Cutaneous disease is common and includes two clinicopathologic categories: granulomatous infiltration or a reactive phenomenon. In the granulomatous infiltrative group, clinical manifestations can be variable. Ulcers in sarcoidosis are uncom...
journal_title:International journal of dermatology
pub_type: 杂志文章
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更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Cutaneous leishmaniasis is a common disease in Iran, especially in the north-east, central and southern parts of the country. Many treatments have been suggested for this disease but none is completely effective and without side-effects such as pain, arthralgia and renal or cardiac complications. Lasers have...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
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更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Necrotizing fasciitis is a severe soft-tissue infection characterized by a fulminant course and high mortality. Early recognition is difficult as the disease is often clinically indistinguishable from cellulitis and other soft-tissue infections early in its evolution. Our aim was to study the manifestations ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2007.03201.x
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:The Section of Dermatology of the University of the Philippines, Philippine General Hospital, reported a case of chronic arsenic poisoning from a community in Luzon island to the Department of Health resulting in the conduct of two health and environmental assessment missions in December 2014. OBJECTIVE:To ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13615
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Primary cutaneous CD4+ small-medium pleomorphic T cell lymphoma (SMPTCL) is a low-grade cutaneous T cell lymphoma. Its clinical and histopathologic features are comparable with those of CD8+ lymphoid proliferations (LPs) of the ear and acral sites. OBJECTIVES:We performed a retrospective analysis of patient...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13340
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Despite their benign nature, keloids are usually associated with considerable cosmetic effects and may lead to functional problems. Recently, it has been reported that vascular endothelial growth factor (VEGF), a potent angiogenic factor, is overexpressed in keloid tissue and may have a potential role in its...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2009.04143.x
更新日期:2009-10-01 00:00:00
abstract::The auricle is a flexible structure because it is formed by elastic cartilage. In the rare occurrence of ectopic auricular ossification, however, the cartilage is replaced by lamellar bone and becomes petrified. Such unphysiological replacement has been reported in association with local trauma, inflammation, systemic...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2007.03512.x
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Demodex mites are almost ubiquitous on older adult skin but are infrequent in young children. In immunocompromised patients, demodicosis may be more frequent and severe, and systemic therapy may be needed to achieve clinical resolution. CASE REPORT:A six-year-old boy having maintenance chemotherapy for acut...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2003.01916.x
更新日期:2003-09-01 00:00:00
abstract::We present two cases of Eosinophilic pustular folliclulitis (EPF) who were successfully treated with topical tacrolimus. Indomethacin is the most frequently used agent for the treatment of EPF, however, tacrolimus ointment may become the treatment of choice for patients with EPF. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02109.x
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:The patient with xeroderma pigmentosum provides an appropriate human model for the evaluation of tumor development and progression. METHODS:We describe a patient with variant-type xeroderma pigmentosum who developed actinic keratoses, a squamous cell carcinoma, and its metastasis into a lymph node. DNA ploi...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1994.tb00990.x
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Basal cell carcinoma (BCC) is one of the most frequent malignancies in the general population. Its best treatment option is the complete excision of the lesion. Mohs' micrographic surgery has demonstrated to be the surgical method with the highest cure rates, however, it is not available in many countries or...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02091.x
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:Sporotrichosis is a chronic granulomatous infection caused by Sporothrichum schenckii. The disease has worldwide distribution. Majority of cases from India are reported from North-eastern states. METHODS:The demographic, clinico-investigative profile and therapeutic results of nine patients with cutaneous s...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03538.x
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:The average incidence of pemphigus reported from European countries ranged between 0.5 and eight cases per one million inhabitants. Studies on epidemiology of pemphigus group in entire Province of Poland over a period of more than a decade are lacking. AIM:To analyze the incidence of pemphigus vulgaris (PV)...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.14078
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Community-associated methicillin-resistant Staphylococci aureus (CA-MRSA) pediatric skin infections have been reported worldwide. However, little is known about pathogens' implications in Egyptian children, and beta-lactams are still the empiric antimicrobials prescribed. This warrants Egyptian studies on an...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2012.05515.x
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:In recent years, an unusual biologic behavior of Merkel cell tumor (MCT) has been noted. In some patients, the tumor was indolent and well controlled by therapy, while in others it was lethal in a few months. Even though the majority of the reported cases are between these two biologic extremes, it seems evi...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1993.tb01470.x
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Tinea pedis is an infrequent disease in children before the age of puberty. There are few epidemiologic and clinical data regarding cases of tinea pedis observed in children. Materials and methods We prospectively collected all cases of tinea pedis in children diagnosed during the years 1995-1997. Only those...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2000.00861.x
更新日期:2000-01-01 00:00:00
abstract::Numerous chemical agents are used in the topical treatment of warts. Monochloroacetic acid (MCAA) is one of these agents, which is used in low or high concentrations in most European countries. MCAA is a strong organic acid which is irritating and corrosive to the skin and has a high systemic toxicity. In addition to ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03789.x
更新日期:2008-12-01 00:00:00
abstract::The role of cell-mediated immunity (CMI) in wart infection was demonstrated. The correlation with humoral immunity was also suggested. Patients with cell-mediated immune deficiency were found to be more susceptible to wart infection than those with humoral immune deficiency. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1982.tb00510.x
更新日期:1982-03-01 00:00:00
abstract:BACKGROUND:Tumor necrosis factor alpha (TNFα) gene -238G/A polymorphism (rs361525) is associated with psoriasis in several populations worldwide. To the best of our knowledge, there is no information about this polymorphism in Indian psoriatic patients. This study was undertaken to fill the gap in knowledge. METHODS:T...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13482
更新日期:2017-03-01 00:00:00
abstract:UNLABELLED:Methotrexate (MTX) treatment for psoriasis is most often administered weekly, because the drug has been considered more hepatotoxic when taken daily. However, some patients may tolerate smaller, more frequent doses better. OBJECTIVE:To study the efficacy and toxicity of daily vs. weekly MTX. PATIENTS AND M...
journal_title:International journal of dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-4632.2011.04967.x
更新日期:2011-10-01 00:00:00
abstract::A 73-year-old Celtic man presented with a linear pigmented 20-mm lesion on the left infraorbital cheek (Fig. 1). Clinical impression was pigmented basal cell epithelioma. Removal was accomplished by linear excision under local anesthesia. The wound was closed with a running 5-0 nylon subcuticular suture, which was rem...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1985.tb05396.x
更新日期:1985-03-01 00:00:00