Demodex infestation in a child with leukaemia: treatment with ivermectin and permethrin.

Abstract:

BACKGROUND:Demodex mites are almost ubiquitous on older adult skin but are infrequent in young children. In immunocompromised patients, demodicosis may be more frequent and severe, and systemic therapy may be needed to achieve clinical resolution. CASE REPORT:A six-year-old boy having maintenance chemotherapy for acute lymphoblastic leukemia presented with widespread erythema and scaling of the face. Skin scrapings were negative and the eruption worsened despite the completion of chemotherapy and the use of topical corticosteroids. Pustules developed on the face and around the eyelids, associated with bilateral blepharitis and lower lid chalazia. Skin biopsy then revealed heavy infestation with Demodex folliculorum. The child was treated with a combination of topical permethrin and oral ivermectin, with a total of four doses of ivermectin given over 6 weeks. The facial eruption had completely resolved 3 months after initiation of this combined treatment. COMMENT:Demodex infestation can cause dramatic facial and eyelid inflammation in immunocompromised patients. Oral ivermectin, in combination with topical permethrin, can be a safe and effective treatment for severe demodicosis.

journal_name

Int J Dermatol

authors

Damian D,Rogers M

doi

10.1046/j.1365-4362.2003.01916.x

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

724-6

issue

9

eissn

0011-9059

issn

1365-4632

pii

1916

journal_volume

42

pub_type

杂志文章
  • Measuring fatigue: a meta-review.

    abstract::There is a lack of validated tools to measure fatigue in patients with inflammatory skin, neuropsychiatric, and medical disorders. The use of nonvalidated tools may compromise the quality of data. The purpose of this meta-review was to evaluate existing fatigue scales commonly used to assess fatigue in other inflammat...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/ijd.15341

    authors: Machado MO,Kang NC,Tai F,Sambhi RDS,Berk M,Carvalho AF,Chada LP,Merola JF,Piguet V,Alavi A

    更新日期:2020-12-10 00:00:00

  • Prevalence of dysplastic nevi in healthy young men.

    abstract::Young white men (1176 men, mean age 20 years, age range from 18 to 26 years) were examined for dysplastic nevi. In 78 patients (6.63%), 107 clinically dysplastic nevi were observed, demonstrating all three NIH criteria (diameter greater than 5mm, irregularities of border, irregularities of color) suggestive for clinic...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1992.tb03947.x

    authors: Peter RU,Worret WI,Nickolay-Kiesthardt J

    更新日期:1992-05-01 00:00:00

  • Mycosis fungoides with oral involvement.

    abstract::Oral mucous membrane involvement occurs uncommonly in mycosis fungoides and reports of it are scarce. We present two patients with severe involvement of the oral mucous membranes. ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1991.tb04353.x

    authors: Vicente A,Martí RM,Martín E,Estrach T,Herrero C,Mascaró JM

    更新日期:1991-12-01 00:00:00

  • Longitudinal progress of transepidermal water loss, color, and sensory elements in split-thickness skin graft donor sites in East Asians.

    abstract:BACKGROUND:There is little research available that describes the natural progression of split-thickness skin graft (STSG) donor site wounds after re-epithelialization. The purpose of this study was to evaluate the longitudinal clinical progress of transepidermal water loss (TEWL), color, and sensory elements in STSG do...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.14389

    authors: Kim J,Kim R,Jeong W,Choi J,Park SW

    更新日期:2019-05-01 00:00:00

  • Polar and subpolar diffuse cutaneous leishmaniasis in Brazil: clinical and immunopathologic aspects.

    abstract:BACKGROUND:Diffuse cutaneous leishmaniasis (DCL) is a rare manifestation of human leishmaniasis, characterized by multiple, slowly progressive nodules or plaques without ulceration, involving almost the entire body. It has been suggested, that DCL results from a lack of cell-mediated immunity to leishmanial antigen, le...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1995.tb00613.x

    authors: Barral A,Costa JM,Bittencourt AL,Barral-Netto M,Carvalho EM

    更新日期:1995-07-01 00:00:00

  • Cutaneous larva migrans (creeping eruption) in an urban slum in Brazil.

    abstract:BACKGROUND:Cutaneous larva migrans (CLM) is caused by the penetration of larvae of animal hookworms into the skin. Knowledge about this ectoparasitosis is mainly based on the examination of travelers or other expatriates. Population-based studies in an endemic area have never been performed. METHODS:A representative p...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2004.02152.x

    authors: Heukelbach J,Wilcke T,Feldmeier H

    更新日期:2004-07-01 00:00:00

  • Downregulation of PTEN expression in psoriatic lesions.

    abstract:BACKGROUND:Considerable studies showed that tumor suppressor phosphatase and tensin homolog (PTEN) deleted on chromosome 10 is a major tumor suppressor, which inhibits cell proliferation through inactivation of the PI3 kinase (PI3K)/Akt signal pathway. In many human tumors, there is loss of function or mutations in PTE...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.12061

    authors: Li Y,Man X,You L,Xiang Q,Li H,Xu B,Chen Z,Zhang X,Lian S

    更新日期:2014-07-01 00:00:00

  • Cutaneous porphyrias part II: treatment strategies.

    abstract::The porphyrias are diverse in pathophysiology, clinical presentation, severity, and prognosis, presenting a diagnostic and therapeutic challenge. Although not easily curable, the dermatological manifestations of these diseases, photosensitivity and associated cutaneous pathology, can be effectively prevented and manag...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/ijd.12016

    authors: Tintle S,Alikhan A,Horner ME,Hand JL,Davis DM

    更新日期:2014-01-01 00:00:00

  • Acyclovir-induced neuropsychosis successfully recovered after immediate hemodialysis in an end-stage renal disease patient.

    abstract::A 70-year-old man developed herpes zoster over the right L5-S2 region for 3 days and was admitted for acyclovir therapy. He had a medical history of rectal cancer status post-colostomy and end-stage renal disease undergoing thrice weekly hemodialysis. Without a prior loading dose, acyclovir 500 mg (7.7 mg/kg) daily wa...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2007.03269.x

    authors: Yang HH,Hsiao YP,Shih HC,Yang JH

    更新日期:2007-08-01 00:00:00

  • Pityriasis in dermatology: an updated review.

    abstract::Dermatology has a very distinctive lexicon. The term pityriasis refers to several dermatologic conditions which all feature scaling of the skin. According to the Merriam-Webster dictionary, the term pityriasis was first used in print in 1684. Although the diseases beginning with the name pityriasis are of diverse caus...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/ijd.15097

    authors: Chin LD,Parvinnejad N,Haber RM

    更新日期:2020-08-11 00:00:00

  • Basal cell carcinoma treated with Mohs micrographic surgery in young Ibero-American patients.

    abstract:BACKGROUND:The incidence of basal cell carcinoma (BCC) in younger individuals has increased in recent decades. However, the characteristics of BCCs in this population, especially in Ibero-Latin American countries, have not been completely defined. OBJECTIVE:To describe the demographic, clinical, and histopathological ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ijd.14195

    authors: Aluma-Tenorio MS,Ávila-Álvarez A,Jaimes N,Caballero-Uribe N,González A,Terzian LR,Ocampo-Candiani J,Zuluaga MA,Garza-Rodríguez V,Tamayo-Betancur MC,Cuesta-Castro DP,Garcés JR,Ruiz-Salas V,Goldberg L,Kimyai-Asadi A

    更新日期:2018-12-01 00:00:00

  • Topical zinc therapy for acne vulgaris.

    abstract::A double-blind study of 30 patients with mild to moderate acne vulgaris was conducted to evaluate the efficacy of a topically applied 2% zinc sulfate solution for acne therapy. Over a 12-week period, no difference was noted between placebo- and zinc-treated participants in regard to either the number or type of acne l...

    journal_title:International journal of dermatology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1365-4362.1985.tb05756.x

    authors: Cochran RJ,Tucker SB,Flannigan SA

    更新日期:1985-04-01 00:00:00

  • Clinical and dermoscopic response predictors in psoriatic patients undergoing narrowband ultraviolet B phototherapy: results from a prospective study.

    abstract:BACKGROUND:Although disease severity, gender, body weight, and previous treatments have all been reported to affect clinical response of psoriasis vulgaris to narrowband ultraviolet B (NB-UVB) therapy, little information about possible local (lesional) influencing factors is available. OBJECTIVE:To assess correlations...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.13983

    authors: Errichetti E,Stinco G

    更新日期:2018-06-01 00:00:00

  • Neuropathic ulcers: a focused review.

    abstract::Neuropathic ulcers or diabetic foot ulcers are preventable ulcers associated with diabetes mellitus. These ulcers occur in the setting of unrecognized trauma, peripheral neuropathy, and foot deformities; however, they are often complicated by peripheral arterial disease and infection. Approximately 15% of individuals ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/ijd.15362

    authors: Urso B,Ghias M,John A,Khachemoune A

    更新日期:2020-12-17 00:00:00

  • Comorbidity of psychiatric disorders in children and adolescents with alopecia areata in a child and adolescent psychiatry clinical sample.

    abstract:BACKGROUND:This study reports the comorbidity of lifetime psychiatric disorders in children and adolescents with alopecia areata (AA) in a child and adolescent psychiatry clinical sample. METHODS:Fourteen patients with AA were interviewed using the Diagnostic and Statistical Manual of Mental Disorders-Fourth edition (...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2008.03743.x

    authors: Ghanizadeh A

    更新日期:2008-11-01 00:00:00

  • Co-presentation of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis and adult-onset infective dermatitis associated with HTLV-1 infection.

    abstract:BACKGROUND:Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), infective dermatitis associated with HTLV-1 (IDH), and various other clinical conditions. Several of these diseases can occur i...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2012.05606.x

    authors: Okajima R,Casseb J,Sanches JA

    更新日期:2013-01-01 00:00:00

  • Tricoadenoma of Nikolowski.

    abstract::The patient, aged 50 years, with no relevant clinical history, complained of a symptomless, soft tumor of the right buttock that had been present for many years. On examination, it was found to be pediculate, oval, somewhat erythematous, firm on palpation, and with a central keratin plug. The greatest diameter of the ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1995.tb04659.x

    authors: Bañuls J,Silvestre JF,Sevila A,Morell A,Betlloch I,Botella R

    更新日期:1995-10-01 00:00:00

  • Efficacy of lipectomy and liposuction in the treatment of multiple symmetric lipomatosis.

    abstract:BACKGROUND:Multiple symmetric lipomatosis (MSL) is a rare disease characterized by enlarging, symmetric, nonencapsulated, fat deposits mainly on the neck and upper trunk. Liposuction and lipectomy, although palliative, are the treatments of choice, especially indicated when vital structures are compromised. OBJECTIVE:...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-4362.1999.00743.x

    authors: Martínez-Escribano JA,Gonzalez R,Quecedo E,Febrer I

    更新日期:1999-07-01 00:00:00

  • Khite: a non-Western technique for temporary hair removal.

    abstract:BACKGROUND:Khite (also known as fatlah in Egypt) is a manual technique of temporary vellus hair removal that is widely performed in the Middle East. METHODS:The technique of khite is reviewed as illustrated. RESULTS:Khite is an effective method of removing unwanted vellus hairs. CONCLUSIONS:Dermatologists in all par...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-4362.1997.00189.x

    authors: Abdel-Gawad MM,Abdel-Hamid IA,Wagner RF Jr

    更新日期:1997-03-01 00:00:00

  • Efficacy of intralesional bleomycin for the treatment of plantar hard corns.

    abstract:BACKGROUND:Intralesional bleomycin is effective for the treatment of various dermatologic conditions. However, the efficacy of intralesional bleomycin for the treatment of corns has not been established. METHODS:A total of 50 patients with plantar corns were recruited and equally divided between groups A and B. Groups...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.12586

    authors: Lee WJ,Lee SM,Won CH,Chang SE,Lee MW,Choi JH,Moon KC

    更新日期:2014-12-01 00:00:00

  • A comparison of neuropeptide expression in skin with allergic contact dermatitis in human and mouse.

    abstract:BACKGROUND:Allergic contact dermatitis (ACD) is a manifestation of a cell-mediated immune response, but its mechanism remains unknown. Recently, we investigated whether ACD involves various neuropeptides. Substance P (SP) is a neuropeptide that is known to act as a neurokinin receptor when the immune response is initia...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2011.05197.x

    authors: Lim YY,Kim HM,Lee HI,Mun SK,Kim CW,Kim MN,Kim BJ

    更新日期:2012-08-01 00:00:00

  • Skin diseases in the Peruvian Amazonia.

    abstract:BACKGROUND:Dermatologic diseases vary widely as a result of geographic location and may be influenced by environmental factors. Aim To determine the epidemiology of dermatological diseases in the Peruvian Amazonia. METHODS:Transversal and multicentric study, which were carried out during February of 2006, 2007, and 20...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1365-4632.2010.04473.x

    authors: Gutierrez EL,Galarza C,Ramos W,Tello M,Jiménez G,Ronceros G,Chía H,Hurtado J,Ortega-Loayza AG

    更新日期:2010-07-01 00:00:00

  • Crystal storing histiocytosis of the skin associated with multiple myeloma.

    abstract:BACKGROUND:Crystal storing histiocytosis (CSH) imitating rhabdomyoma is a very rare disease entity involving different tissues. The skin is involved in extremely rare cases. OBJECTIVES:To describe the clinical and histopathological characteristics in a patient with unusually extensive skin involvement. OBSERVATIONS:A...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2006.02919.x

    authors: Pock L,Stuchlík D,Hercogová J

    更新日期:2006-12-01 00:00:00

  • A comparative study of various modalities in the treatment of keloids.

    abstract:INTRODUCTION:Treatment of keloids is a challenge as a result of paucity of effective treatment modalities, significant side effects, and their recurrent nature. In this study, various treatment modalities were compared to search for a treatment option with maximum efficacy and minimum side effects. METHODS:One hundred...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ijd.14069

    authors: Aggarwal A,Ravikumar BC,Vinay KN,Raghukumar S,Yashovardhana DP

    更新日期:2018-10-01 00:00:00

  • Papulonecrotic tuberculid secondary to disseminated Mycobacterium avium complex.

    abstract:BACKGROUND:Papulonecrotic tuberculid is a rarely reported cutaneous reaction to the mycobacterium bacillus. It is most often encountered in association with tuberculosis. The clinical and histologic picture of the entity is a distinctive one, but the etiology of the disease process is uncertain. Therapy directed agains...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1994.tb01537.x

    authors: Williams JT,Pulitzer DR,DeVillez RL

    更新日期:1994-02-01 00:00:00

  • Lichen planus and dyslipidemia: a systematic review and meta-analysis of observational studies.

    abstract:BACKGROUND:Lichen planus (LP) is a chronic inflammatory disease that has been shown to be positively associated with dyslipidemia. However, the magnitude and types of the underlying lipid abnormalities have not been investigated. This study aims to conduct a systematic review and meta-analysis to investigate the qualit...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/ijd.13234

    authors: Lai YC,Yew YW,Schwartz RA

    更新日期:2016-05-01 00:00:00

  • Hypertrophic lichen planus and light sensitivity in an HIV-positive patient.

    abstract::A 40-year-old black man who was HIV positive developed generalized hypertrophic lichen planus in areas previously affected by a photosensitivity eruption. After unsuccessful attempts to induce remission of his lichen planus with conventional therapies, etretinate produced a dramatic response. ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1988.tb02423.x

    authors: Pardo RJ,Kerdel FA

    更新日期:1988-11-01 00:00:00

  • Pemphigus vegetans of the oral cavity.

    abstract:BACKGROUND:Pemphigus vegetans, a variant of pemphigus vulgaris, constitutes a rare form of all pemphigus cases, and oral involvement is common. Two clinical subtypes of pemphigus vegetans exist, characterized initially by flaccid bullae and erosions (Neumann) or pustules (Hallopeau). Both subtypes subsequently develop ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2004.02480.x

    authors: Markopoulos AK,Antoniades DZ,Zaraboukas T

    更新日期:2006-04-01 00:00:00

  • Malignant melanoma in World War II veterans.

    abstract::In a consecutive series of 1,067 patients entered into the data base of the Melanoma Cooperative Group at New York University School of Medicine between 1972 and 1980, 120 men were of draft age (18-31 years) during World War II (1941-1945). Questionnaires were sent to these 120 individuals; 89 responded. Simultaneousl...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1984.tb01228.x

    authors: Brown J,Kopf AW,Rigel DS,Friedman RJ

    更新日期:1984-12-01 00:00:00

  • Mycetoma in South India: retrospective analysis of 13 cases and description of two cases caused by unusual pathogens: Neoscytalidium dimidiatum and Aspergillus flavus.

    abstract:BACKGROUND:Mycetoma is a chronic suppurative and/or granulomatous inflammatory lesion of skin, subcutaneous tissue, fascia, and tendons caused by the traumatic inoculation of either fungal (eumycotic) or bacterial (actinomycotic) organisms present in the soil. The disease is characterized by triad of tumefaction, disch...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2010.04610.x

    authors: Padhi S,Uppin SG,Uppin MS,Umabala P,Challa S,Laxmi V,Prasad VB

    更新日期:2010-11-01 00:00:00