Downregulation of PTEN expression in psoriatic lesions.

abstract：:Omalizumab is a recombinant humanized monoclonal antibody targeting the high-affinity Fc receptor of IgE, registered for the treatment of chronic spontaneous urticaria and severe allergic asthma. We present a case series of nine patients with atopic dermatitis (AD) treated off-label with omalizumab and a systematic re...

journal_title：International journal of dermatology

authors： Holm JG,Agner T,Sand C,Thomsen SF

更新日期：2017-01-01 00:00:00

abstract：:Dapsone (4,4'-diaminodiphenylsulfone) is the only remaining sulfone used in anthropoid therapeutics and is commercially available as an oral formulation, an inhaled preparation, and a 5% or 7.5% cream. Dapsone has antimicrobial effects stemming from its sulfonamide-like ability to inhibit the synthesis of dihydrofolic...

journal_title：International journal of dermatology

authors： Ghaoui N,Hanna E,Abbas O,Kibbi AG,Kurban M

更新日期：2020-07-01 00:00:00

abstract：UNLABELLED:Methotrexate (MTX) treatment for psoriasis is most often administered weekly, because the drug has been considered more hepatotoxic when taken daily. However, some patients may tolerate smaller, more frequent doses better. OBJECTIVE:To study the efficacy and toxicity of daily vs. weekly MTX. PATIENTS AND M...

journal_title：International journal of dermatology

authors： Radmanesh M,Rafiei B,Moosavi ZB,Sina N

更新日期：2011-10-01 00:00:00

abstract：:The major characteristics of tricho-rhino-phalangeal syndrome (TRPS) include shortened and deviated digits, a typical facies with a pear-shaped nose, a long philtrum and slow-growing, fine, sparse hair. Cone-shaped digital epiphyses are seen on x-ray. A few patients with TRPS are mentally retarded. Associated endocrin...

journal_title：International journal of dermatology

authors： Hansen DD,Shewmake SW

更新日期：1979-09-01 00:00:00

abstract：OBJECTIVE:We performed a prospective study to evaluate the diagnostic accuracy of cytologic examination in basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs), in order to assess its clinical value. Study design Samples were taken by the "scraping" technique which involves scraping with a scalpel blade dir...

journal_title：International journal of dermatology

authors： Vega-Memije E,De Larios NM,Waxtein LM,Dominguez-Soto L

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Targeted therapies and immunotherapies are increasingly prescribed, but classic chemotherapy agents are still highly used in cancer treatment. Both therapies, the old and the new, are associated with cutaneous adverse events (CAEs) that can cause treatment interruptions or reduce the quality of life of patie...

journal_title：International journal of dermatology

authors： Suh HJ,Flórez Á,Sacristán V,Rodríguez Martinez Á,Fernández F,Vilanova-Trillo L,Constenla M,Pereiro M

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:In the Irish health system, dermatology patients present to their family practitioner for diagnosis and treatment, and are referred to a dermatologist for a second opinion where diagnosis is in doubt or when there has been therapeutic failure. The level of expertise in dermatology amongst family practitioner...

journal_title：International journal of dermatology

authors： Morrison A,O'Loughlin S,Powell FC

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Buschke-Ollendorff syndrome is a rare autosomal dominant disease featuring osteopoikilosis and skin lesions. It is caused by genetic mutations in a protein deeply involved in bone and connective tissue morphogenesis. METHODS:We describe a 39-year-old woman with Buschke-Ollendorff syndrome. RESULTS:After a ...

journal_title：International journal of dermatology

authors： Schena D,Germi L,Zamperetti MR,Colato C,Girolomoni G

更新日期：2008-11-01 00:00:00

abstract：:BACKGROUND Hair loss occurs in all ethnic populations, but the etiology varies considerably from group to group. In black women, many forms of alopecia are associated with hair care practices. However, the causes of alopecias in African women have not been extensively investigated. OBJECTIVE This descriptive, cross-se...

journal_title：International journal of dermatology

authors： Nnoruka EN

更新日期：2005-10-01 00:00:00

abstract：:Skin lesions are frequent in human T-cell lymphotropic virus type 1 (HTLV-1) infection and may constitute an alert for the diagnosis of this condition. The most severe skin diseases related to this virus are adult T-cell leukemia/lymphoma (ATLL), an aggressive form of leukemia/lymphoma that fails to respond to chemoth...

journal_title：International journal of dermatology

authors： Bittencourt AL,de Oliveira Mde F

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:The usefulness of the lupus band test (LBT) in the diagnosis of cutaneous lupus erythematosus remains controversial. The study was done to determine the sensitivity, specificity, and predictive value of the LBT in discoid lupus erythematosus (DLE) and systemic lupus erythematosus (SLE). METHODS:During the s...

journal_title：International journal of dermatology

authors： George R,Kurian S,Jacob M,Thomas K

更新日期：1995-03-01 00:00:00

abstract：:We present two cases of Eosinophilic pustular folliclulitis (EPF) who were successfully treated with topical tacrolimus. Indomethacin is the most frequently used agent for the treatment of EPF, however, tacrolimus ointment may become the treatment of choice for patients with EPF. ...

journal_title：International journal of dermatology

authors： Kawaguchi M,Mitsuhashi Y,Kondo S

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:There are few published guidelines that describe the forethought and logistical considerations needed to create a dermatology-specific medical mission. OBJECTIVE:To report the experience of planning and executing a successful medical mission to an underserved community in Puerto Rico. METHODS:We identified...

journal_title：International journal of dermatology

authors： Ramirez-Fort MK,Lastra-Vicente R,Levitt JO,Sanchez JL,Reizner GT

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The use of Isotretinoin (Iso) for cystic acne (CA) therapy includes marked side-effects such as dyslipidemia, increased liver enzymes, and reduction of biotinidase activity. Moreover, Homocysteine (Hcy), an amino acid, is metabolized in the liver requiring folate, vitamin B6, vitamin B12, and the activity of...

journal_title：International journal of dermatology

authors： Schulpis KH,Karikas GA,Georgala S,Michas T,Tsakiris S

更新日期：2001-01-01 00:00:00

abstract：:A clinical trial using tretinoin lotion 0.05%, benzoyl peroxide 5% and 10% as topical application was performed on 250 ambulatory patients suffering from various degrees of acne vulgaris. The results indicate that tretinoin applied in the morning and benzoyl peroxide applied at night is the most efficacious regimen to...

journal_title：International journal of dermatology

authors： Handojo I

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Postadolescent acne is defined as acne that is seen even after the age of 25 years, regardless of the age at onset. The causes of postadolescent acne have not been completely clarified up to now. Androgens are considered to be the major factor involved in pathogenesis. OBJECTIVE:We aimed to investigate the ...

journal_title：International journal of dermatology

authors： Ekiz O,Balta I,Unlu E,Bulbul Sen B,Rifaioğlu EN,Dogramaci AC

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The relationships between androgenetic alopecia (AGA) and various factors related to metabolic syndrome have been demonstrated in previous studies. However, it remains unclear because of inconsistent results. We investigated the associations between AGA and various risk factors related to metabolic syndrome ...

journal_title：International journal of dermatology

authors： Kim BK,Choe SJ,Chung HC,Oh SS,Lee WS

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Phototherapy is already established as an effective mode of therapy in vitiligo. An evidence-based study was carried out of the effect of narrow-band (311 nm) ultraviolet-B (NB-UV-B) radiation in 66 surgically treated patients with recalcitrant vitiligo in whom autologous mini-punch grafting was deployed. M...

journal_title：International journal of dermatology

authors： Lahiri K,Malakar S,Sarma N,Banerjee U

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Self-reported complaints in people having tattoos, including swelling, itch, and photosensitivity, are frequent. Tattooists are usually heavily tattooed with multiple extended colored tattoos and constitute a specific population of interest. OBJECTIVES:To assess the prevalence of cutaneous complications on ...

journal_title：International journal of dermatology

authors： Kluger N

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Atrophic acne scars are a frequent problem after acne. Hitherto, mainly invasive treatment measures were possible. In a recent paper, we demonstrated the positive effects of iontophoresis with 0.025% tretinoin gel vs. estriol 0.03%. OBJECTIVE:In this further study, the recording of the clinical effects of i...

journal_title：International journal of dermatology

authors： Schmidt JB,Donath P,Hannes J,Perl S,Neumayer R,Reiner A

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Liver enzymes appear to be involved in oral lichen planus (OLP), but it is not known whether the elevation develops concomitantly with exacerbations of disease. We compared the levels of serum hepatic aspartate (AST) and alanine (ALT) aminotransferases as markers of OLP exacerbation in patients with chronic ...

journal_title：International journal of dermatology

authors： Bombeccari GP,Tettamanti M,Pallotti F,Spadari F,Giannì AB

更新日期：2017-08-01 00:00:00

abstract：:Previous reports have shown that alterations in cutaneous and plasmatic fibrinolytic activity are found in cutaneous necrotizing vasculitis (CNV). In a combined investigation with direct immunofluorescence and autohistographic evaluation of tissue fibrinolytic activity in the lesional skin of 20 subjects affected by S...

journal_title：International journal of dermatology

authors： Bianchini G,Lotti T,Fabbri P

更新日期：1983-03-01 00:00:00

abstract：:Scleromyxedema is a rare disease characterized by papular mucinous deposits, dermal fibroblast proliferation, and a monoclonal paraproteinemia. Its chronic course tends to be complicated by gastrointestinal, muscular, pulmonary, and neurologic disorders. We review the literature to identify the common systemic manifes...

journal_title：International journal of dermatology

authors： Pomann JJ,Rudner EJ

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND DESIGN:The clinical, histologic, and direct (DIF) and indirect (IIF) immunofluorescence findings are used in a critical, although arbitrary, manner in the routine diagnostic process of bullous pemphigoid (BP). Our purpose was to estimate their relative value. In the present retrospective study, a follow-...

journal_title：International journal of dermatology

authors： Chaidemenos GC,Maltezos E,Chrysomallis F,Kouskoukis K,Kapetis E,Mourellou O,Gotsis N

更新日期：1998-03-01 00:00:00

abstract：:There is some debate regarding the risk of developing malignancy and progression of malignancy in patients with psoriasis treated with biologics. The lack of extensive, long-term, and large studies, including patients with psoriasis, to assess these aforementioned risks makes it difficult to ascertain the safety profi...

journal_title：International journal of dermatology

authors： Patel S,Patel T,Kerdel FA

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Mohs micrographic surgery (MMS) is used to treat cutaneous malignancies in locations to maximize tissue sparing. The authors' aim is to demonstrate the utility of conservative thickness layers (CTL) in MMS and review patient and tumor characteristics and the potential anatomic locations where this technique ...

journal_title：International journal of dermatology

authors： Tolkachjov SN,Cappel JA,Bryant EA,Harmon CB

更新日期：2018-09-01 00:00:00

abstract：:A male fetus which was the product of full-term pregnancy and normal delivery with no family history is presented. The skin was hard and thick, waxy, yellowish in color, and was crossed by horizontal and or perpendicular red fissures. The eyelids were semiclosed, hard, and stiff resulting in ectropion and the conjunct...

journal_title：International journal of dermatology

authors： Kouskoukis C,Minas A,Tousimis D

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:The incidence of basal cell carcinoma (BCC) in younger individuals has increased in recent decades. However, the characteristics of BCCs in this population, especially in Ibero-Latin American countries, have not been completely defined. OBJECTIVE:To describe the demographic, clinical, and histopathological ...

journal_title：International journal of dermatology

authors： Aluma-Tenorio MS,Ávila-Álvarez A,Jaimes N,Caballero-Uribe N,González A,Terzian LR,Ocampo-Candiani J,Zuluaga MA,Garza-Rodríguez V,Tamayo-Betancur MC,Cuesta-Castro DP,Garcés JR,Ruiz-Salas V,Goldberg L,Kimyai-Asadi A

更新日期：2018-12-01 00:00:00

abstract：:Bazex-Dupré-Christol syndrome is a rare genodermatosis that manifests with the classical triad of basal cell carcinoma, follicular atrophoderma, and hypotrichosis; yet it may be accompanied by milia, ichthyosis, neurological symptoms, and visceral malignancies. Symptom onset is nonsimultaneous, and hence the diagnosis...

journal_title：International journal of dermatology

authors： AlSabbagh MM,Baqi MA

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:The use of lasers is very common in dermatology; however, many patients fear it and have various misconceptions about it. A literature search failed to show any studies on this topic. OBJECTIVE:To explore the various misconceptions of patients about lasers in dermatology. METHODS:A self-administered questi...

journal_title：International journal of dermatology

authors： AlGhamdi KM,Moussa NA

更新日期：2011-11-01 00:00:00