Buschke-Ollendorff syndrome.

Abstract:

BACKGROUND:Buschke-Ollendorff syndrome is a rare autosomal dominant disease featuring osteopoikilosis and skin lesions. It is caused by genetic mutations in a protein deeply involved in bone and connective tissue morphogenesis. METHODS:We describe a 39-year-old woman with Buschke-Ollendorff syndrome. RESULTS:After a minor trauma, radiologic examination of the left ankle of a 39-year-old woman revealed features of osteopoikilosis. Physical examination of the patient showed multiple asymptomatic nodules on both thighs, present since the age of 20 years, which had increased in size and number. Recently, a linear, string-like lesion had appeared on the right thigh. CONCLUSION:The correct diagnosis of Buschke-Ollendorff syndrome may require a high index of suspicion.

journal_name

Int J Dermatol

authors

Schena D,Germi L,Zamperetti MR,Colato C,Girolomoni G

doi

10.1111/j.1365-4632.2008.03727.x

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

1159-61

issue

11

eissn

0011-9059

issn

1365-4632

pii

IJD3727

journal_volume

47

pub_type

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