Abstract:
BACKGROUND:Buschke-Ollendorff syndrome is a rare autosomal dominant disease featuring osteopoikilosis and skin lesions. It is caused by genetic mutations in a protein deeply involved in bone and connective tissue morphogenesis. METHODS:We describe a 39-year-old woman with Buschke-Ollendorff syndrome. RESULTS:After a minor trauma, radiologic examination of the left ankle of a 39-year-old woman revealed features of osteopoikilosis. Physical examination of the patient showed multiple asymptomatic nodules on both thighs, present since the age of 20 years, which had increased in size and number. Recently, a linear, string-like lesion had appeared on the right thigh. CONCLUSION:The correct diagnosis of Buschke-Ollendorff syndrome may require a high index of suspicion.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Schena D,Germi L,Zamperetti MR,Colato C,Girolomoni Gdoi
10.1111/j.1365-4632.2008.03727.xsubject
Has Abstractpub_date
2008-11-01 00:00:00pages
1159-61issue
11eissn
0011-9059issn
1365-4632pii
IJD3727journal_volume
47pub_type
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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journal_title:International journal of dermatology
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更新日期:2004-12-01 00:00:00
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doi:10.1111/j.1365-4362.1993.tb02790.x
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更新日期:2008-04-01 00:00:00
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journal_title:International journal of dermatology
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