Scleromyxedema revisited.

Abstract:

:Scleromyxedema is a rare disease characterized by papular mucinous deposits, dermal fibroblast proliferation, and a monoclonal paraproteinemia. Its chronic course tends to be complicated by gastrointestinal, muscular, pulmonary, and neurologic disorders. We review the literature to identify the common systemic manifestations and suggest a clinical approach to this disorder. This should include: identification of the characteristic lesions, a skin biopsy, and serum protein electrophoresis. A thyroid evaluation may help differentiate this condition from others. An early neurologic, gastrointestinal, and cardiovascular evaluation should be considered.

journal_name

Int J Dermatol

authors

Pomann JJ,Rudner EJ

doi

10.1046/j.1365-4362.2003.01565.x

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

31-5

issue

1

eissn

0011-9059

issn

1365-4632

pii

1565

journal_volume

42

pub_type

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