Abstract:
:To date, various treatment modalities have failed to produce consistent improvement in patients having Behçet's disease. Recent reports in the literature, however, have shown promising results with the use of colchicine. Our patient, an 18-year-old white woman, satisfied the 1977 Istanbul Conference criteria for Behçet's disease by exhibiting ocular inflammation and a five-year history of severe, recurrent oral and vaginal ulcerations. She was treated with 0.6 mg of colchicine orally twice daily, and at the end of two weeks of treatment, the oral lesions had completely resolved, and the vaginal ulcers were reduced in diameter and depth to at least one half. Within one month all oral and vaginal ulcers were completely healed.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Harper RM,Allen BSdoi
10.1111/j.1365-4362.1982.tb01202.xsubject
Has Abstractpub_date
1982-11-01 00:00:00pages
551-4issue
9eissn
0011-9059issn
1365-4632journal_volume
21pub_type
杂志文章abstract:BACKGROUND:Skin disease is a common problem, accounting for significant morbidity in developing countries. Knowledge about the prevalence of different skin conditions allows appropriate planning for provision for these health needs. There are currently few data about the needs in rural areas; therefore, this study was ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1996.tb03688.x
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Neutrophils play a critical role in host defense against a variety of microbial pathogens. There is much information to suggest a role for vitamin C in the physiology of neutrophils. Thus, the effects of vitamin C treatment were studied in a patient with a history of recurrent furunculosis who showed altered...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1993.tb02780.x
更新日期:1993-11-01 00:00:00
abstract::One hundred thirteen patients with fixed drug eruption (FDE) were studied for any drug-specific clinical pattern. The causative drugs were identified and confirmed by provocation tests. A trimethoprim-sulfamethoxazole combination caused maximum incidence (36.3%), followed by tetracycline (15.9%), pyrazolones (14.2%), ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1991.tb04354.x
更新日期:1991-12-01 00:00:00
abstract:BACKGROUND:Pruritus is a common subjective symptom of psoriasis whose levels may be affected by a range of variables. The objective of this study was to evaluate the frequency of pruritus and its associations with clinical and psychological characteristics of psoriasis patients. MATERIALS AND METHODS:One-hundred and s...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12074
更新日期:2014-07-01 00:00:00
abstract::Skin cancers are the most common malignancies and, historically, ionizing radiation has played an important role in their treatment. However, less experienced dermatologists generally consider radiation last in the line of therapeutic options. The authors sought to evaluate the effectiveness and safety of office-based...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2006.03108.x
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Basal cell carcinomas (BCCs) are the most frequent human cancer that results from malignant transformation of basal cells in the epidermis. Gorlin syndrome is a rare inherited autosomal dominant disease that predisposes with multiple BCCs and other birth defects. Both sporadic and inherited BCCs are associat...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2010.04866.x
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:COVID-19 cutaneous manifestations have been recently described and classified in five different clinical patterns, including acral erythema-edema (pseudo-chilblain), maculopapular exanthemas, vesicular eruptions, urticarial lesions, and livedo or necrosis. OBJECTIVES:The objective of this study was to exami...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.15180
更新日期:2020-09-24 00:00:00
abstract:BACKGROUND:Potent teratogenicity limits the use of isotretinoin among females of childbearing potential (FCBP). OBJECTIVE:To explore the current practice of dermatologists for pregnancy prevention when prescribing isotretinoin for FCBP. MATERIALS AND METHODS:A self-administered questionnaire was distributed to 160 de...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.04875.x
更新日期:2011-09-01 00:00:00
abstract::A 58-year-old woman with ulcerative colitis of 5 years' duration was first seen in March 2002 with a 5-month history of widespread erosions on the palate and gingiva, subtle scarring of the conjunctiva, and xerostomia accompanying a flare of ulcerative colitis. No skin lesions were observed. Direct immunofluorescence ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2006.02961.x
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Mycosis fungoides is a lymphoma of cutaneous origin characterized by a proliferation of cells with a T phenotype. METHODS:In this pilot study, 13 men with mycosis fungoides in various stages were treated with alpha-2b interferon and etretinate. RESULTS:In ten of them, such a therapy proved to be effective ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1993.tb01458.x
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:Hand dermatitis is an acute or chronic inflammation of the skin of the hands from a multifactorial cause which may be endogenous, exogenous, or a combination of both. With a wide range in severity and recurrent periods of flares, it has significant impact on the quality of life of its sufferers. A history of...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13845
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The aim was to examine cadexomer iodine paste in a comparative clinical trial. METHODS:A 12-week, randomized, open, controlled, multicenter, multinational trial in patients with exudating, venous leg ulcers of cadexomer iodine paste (Iodosorb/Iodoflex), hydrocolloid dressing (Duoderm E, Granuflex E), or par...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1046/j.1365-4362.1998.00415.x
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Mucosa-associated epithelial chemokine (MEC; CCL28) is considered to be pivotal in mediating the migration of CC chemokine receptor 3- and 10- (CCR3- and CCR10)-expressing, skin-homing, memory, cutaneous lymphocyte-associated antigen-positive (CLA(+)) T cells. CCL28 is selectively and continuously expressed ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2009.04069.x
更新日期:2009-08-01 00:00:00
abstract::A case report of cutaneous onchocercias acquired during travels to Africa is presented. The salient epidemiologic, clinical, diagnostic, and therapeutic aspects are reviewed. Clinical and laboratory differences between onchocerciasis patients who are inhabitants of endemic areas and those who are occasional visitors t...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02203.x
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:The Psoriasis Area and Severity Index (PASI) is used to quantify the extent of the disease, and to evaluate its improvement with treatment. It is considered to be a slow, rough, nonsensitive, and complex tool, with high interobserver variability and low reproducibility. OBJECTIVES AND METHODS:To develop a s...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2000.00017.x
更新日期:2000-12-01 00:00:00
abstract::Atypical presentations of cutaneous tuberculosis are not so uncommon and are frequently overlooked in clinical practice, leading to late diagnosis and increased morbidity. We report three cases of lupus vulgaris with atypical presentations. The cases mimicked other chronic skin lesions like actinomycosis, mycetoma, an...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2009.03863.x
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Harlequin ichthyosis (HI) is a severe genetic disorder caused by the mutation in the ABCA12 gene. Infants born with this condition have markedly thickened, hard stratum corneum skin all over the body. METHODS:A female child born with a thick white plate of skin with deep cracks all over the body was investi...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13923
更新日期:2018-04-01 00:00:00
abstract::Diaper dermatitis is a common condition that often prompts parents to seek medical attention. Irritant diaper dermatitis is by far the most common cause, but numerous potentially serious diseases can present with changes of the skin in the diaper area. The differential diagnosis can include psoriasis, metabolic disord...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.13372
更新日期:2016-07-01 00:00:00
abstract::Young white men (1176 men, mean age 20 years, age range from 18 to 26 years) were examined for dysplastic nevi. In 78 patients (6.63%), 107 clinically dysplastic nevi were observed, demonstrating all three NIH criteria (diameter greater than 5mm, irregularities of border, irregularities of color) suggestive for clinic...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1992.tb03947.x
更新日期:1992-05-01 00:00:00
abstract::The epidemiology of scabies for the last twelve years has been studied in Turkey. Information was obtained from three regions (Istanbul, Ankara and Erzurum) having different climates. There has been an increase in scabies in the years following 1969 in Ankara and Erzurum and from 1967 on in Istanbul. It reached its ma...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1980.tb01993.x
更新日期:1980-01-01 00:00:00
abstract::There is a lack of validated tools to measure fatigue in patients with inflammatory skin, neuropsychiatric, and medical disorders. The use of nonvalidated tools may compromise the quality of data. The purpose of this meta-review was to evaluate existing fatigue scales commonly used to assess fatigue in other inflammat...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/ijd.15341
更新日期:2020-12-10 00:00:00
abstract:BACKGROUND:Matrine is a traditional Chinese medicine with significant inhibitory activity against malignant tumors. Its effects on the invasiveness and metastasis of malignant tumors have rarely been reported. AIM:To investigate whether matrine can inhibit the metastasis-related activities of the human malignant melan...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03627.x
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:In vitiligo, other than loss of melanocytes and melanin pigment in the lesional skin, keratinocytes are also involved. Human fetal Merkel cells are now generally considered to be derived from the epidermis. To date, no observations on Merkel cells in lesional skin of active vitiligo have been reported. METH...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1994.tb02859.x
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:Oral 8-methoxypsoralen is the drug of choice in photochemotherapy of several dermatoses, e.g., vitiligo and psoriasis. The aim of this trial is to produce a new preparation of the drug, which is able to overcome the difficulties met with the oral use of the older preparations. METHODS:A new preparation cont...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-4362.1994.tb02904.x
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:In July 2008, the German statutory health insurance introduced a nationwide skin cancer screening program. Before the introduction, eligible physicians had to qualify to perform the screening test and counsel their patients on skin cancer screening. To educate physicians, a curriculum and training materials ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13688
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Reed's nevi are distinguished from Sptiz tumors by their significant melanogenesis and growth pattern. They may be confused with melanoma on clinical and histologic grounds. CASE REPORT:An unusual case in which multiple agminated Reed's nevi mimicked acral lentiginous malignant melanoma in an African-Americ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1993.tb04268.x
更新日期:1993-04-01 00:00:00
abstract:BACKGROUND:Psoriasis is a chronic, inflammatory, and recurrent dermatological disease. In the Côte d'Ivoire, it is about 0.75% of dermatology cases. Psoriasis care is challenging in elderly patients. We aimed to show its specificities related to the sociodemographic, clinical, and therapeutic aspects, and follow-up in ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13138
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Tranexamic acid (TA) is a traditional plasmin inhibitor, and its role in the renovation of damaged skin has become the topic of a lot of research. The aim of this study is to determine whether TA could repair the skin barrier by means of tight intercellular junctions. METHODS:Two kinds of damaged skin model...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12099
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:The Israel Defense Forces (IDF) medical records offer a unique and valid 28-year view of the striking differences in cutaneous leishmaniasis (CL) seasonality patterns and incidence rates between the military and civilian sectors in Israel. AIM:To determine the annual epidemiology and seasonality trends of C...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2009.03979.x
更新日期:2009-06-01 00:00:00
abstract::Actinic granuloma is a rare skin disorder that develops in an area of actinic elastosis. The pathogenesis of the disease is obscure but the most accepted hypothesis implicates the solar radiation as the triggering factor. Typically the disease presents in middle-aged individuals with significant past sun-exposure and ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2005.02043.x
更新日期:2005-02-01 00:00:00