Abstract:
:Skin cancers are the most common malignancies and, historically, ionizing radiation has played an important role in their treatment. However, less experienced dermatologists generally consider radiation last in the line of therapeutic options. The authors sought to evaluate the effectiveness and safety of office-based elective radiation therapy for cutaneous carcinoma. A retrospective study of 604 basal cell carcinomas (BCCs) and 106 squamous cell carcinomas (SCCs) irradiated between 1971-96 was performed. The percentage of patients who developed tumor recurrence during the follow-up period was calculated using Kaplan-Meier survival curves. Cox's proportional model was used to assess the prognostic factors that might have influenced the recurrences. The recurrence rates for BCC and SCC were 11.5 and 16.5 per 1000 patient-years, respectively. The 5-year cure rates were 94.4% for BCC and 92.7% for SCC, and the 15-year cure rates were 84.8% and 78.6%, respectively. Tumor location on the nasolabial fold (OR 4.4; 95% IC, 1.3-14.7) and tumor size > or = 10 mm (OR 2.14; 95% IC, 1.03-4.45) were independent predictors of BCC recurrence. This study suggested that radiation therapy is an effective treatment for BCC and SCC and should be considered as a first option in many cases.
journal_name
Int J Dermatoljournal_title
International journal of dermatologyauthors
Hernández-Machin B,Borrego L,Gil-García M,Hernández BHdoi
10.1111/j.1365-4632.2006.03108.xsubject
Has Abstractpub_date
2007-05-01 00:00:00pages
453-9issue
5eissn
0011-9059issn
1365-4632pii
IJD3108journal_volume
46pub_type
杂志文章abstract:BACKGROUND:There is a worrying lack of epidemiological data on the geographical distribution and burden of subcutaneous mycoses in Peru, hindering the implementation of surveillance and control programs. OBJECTIVES:This study aimed to estimate the disease burden of subcutaneous mycoses in Peru and identify which funga...
journal_title:International journal of dermatology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ijd.13665
更新日期:2017-10-01 00:00:00
abstract::Chronic idiopathic urticaria (CIU), characterized by the appearance of itchy wheals of unknown etiology, can be extremely debilitating and can significantly reduce a patient's quality of life (QOL). Fexofenadine, a non-sedating, H1-receptor selective, long-acting antihistamine, is licensed worldwide for the treatment ...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1046/j.1365-4362.2002.01599.x
更新日期:2002-10-01 00:00:00
abstract::A 10-year-old immunocompetent boy presented with multiple, verrucous, disseminated pheohyphomycotic lesions caused by Exophiala spinifera. The patient was not responsive to combination antifungal therapy (itraconazole, terbinafine, fluconazole) and cryotherapy. As antifungal susceptibility is known to be variable for ...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4632.2007.03430.x
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Genetic factors seem to play a significant role in the susceptibility to systemic lupus erythematosus (SLE). Some researchers have described amino acid polymorphisms within the interleukin-4 receptor (IL-4R) [isoleucine50valine (Ile50Val), arginine576glutamine (Arg576Gln), etc.], the IL-10R (G241A and G520A)...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2007.03258.x
更新日期:2007-11-01 00:00:00
abstract:UNLABELLED:Methotrexate (MTX) treatment for psoriasis is most often administered weekly, because the drug has been considered more hepatotoxic when taken daily. However, some patients may tolerate smaller, more frequent doses better. OBJECTIVE:To study the efficacy and toxicity of daily vs. weekly MTX. PATIENTS AND M...
journal_title:International journal of dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-4632.2011.04967.x
更新日期:2011-10-01 00:00:00
abstract::We have reviewed the outstanding facts about mycetoma, including the history, first reports in India, the different causal agents according to their geographic distribution, mycologic characteristics, pathology, microbiology, behavior, evolution, immunology, experimental inoculations, associated bacterial complication...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4362.1984.tb01238.x
更新日期:1984-05-01 00:00:00
abstract:BACKGROUND:Primary cutaneous lymphoma (PCL) represents a heterogeneous collection of non-Hodgkin lymphomas originating in the skin. Our study describes the clinical and histological findings of cutaneous lymphoma within Botswana to expand the paucity of data on this rare disease in sub-Saharan Africa. METHODS:We condu...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.14690
更新日期:2020-03-01 00:00:00
abstract::Acquired facial hyperpigmentation is a common problem among African patients, particularly women, where the causes of the dermatoses are identified largely from circumstantial evidence of exposure to known agents. These include hydroquinone-induced exogenous ochronosis from skin-bleaching creams, mercury deposits from...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4362.1991.tb03848.x
更新日期:1991-03-01 00:00:00
abstract::Trimethylpsoralen, psoralen and 8-methoxypsoralen were adminstered in 10 mg dosage orally to 37, 29 and 23 patients with vitiligo. Complete improvement was noted in 8.9% and partial improvement was recorded in 59.5%. The overall results produced by trimethylpsoralen and psoralen were superior to those of 8-methoxyps...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/ijd.1975.14.3.205
更新日期:1975-04-01 00:00:00
abstract::A 57-year-old woman with mycosis fungoides developed blisters within cutaneous plaques while receiving PUVA therapy and topical nitrogen mustard. Direct and indirect immunofluorescence studies showed the findings of bullous pemphigoid. Her bullous disease was controlled after cessation of these therapies and instituti...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1985.tb05751.x
更新日期:1985-04-01 00:00:00
abstract:BACKGROUND:Most treatment protocols for vitiligo usually do not result in complete repigmentation. Therefore, cosmetically acceptable camouflage, low cost and easy to handle alternatives are warranted. OBJECTIVE:To evaluate the efficacy of low-cost self-tanner available in the Thai market in normal subjects with skin ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2008.03356.x
更新日期:2008-04-01 00:00:00
abstract::Ten patients with chronic purpuric and pigmented angiodermatitis in the extremities and two patients with acute and disseminated eczematoid-like purpura angiodermatitis were studied with current hemostasis parameters: (1) platelet aggregation, (2) platelet circulating aggregates, (3) clotting factor measurements and h...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1992.tb04244.x
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:Tuberous sclerosis is an autosomal dominant disorder with hamartomas in multiple organ systems. Facial angiofibromas (AF) are a common cutaneous manifestation of tuberous sclerosis. They may lead to significant cosmetic and psychological problems. Many treatment modalities have been used with variable satisf...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12384
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Chemotherapy-induced acral erythema is a distinct localized cutaneous response to certain systemic chemotherapeutic agents. METHODS:Between January 1990 and December 1994, from a total of 76 leukemic patients who have received combination chemotherapy consisting of cytosine arabinoside and anthracycline ant...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.1997.00040.x
更新日期:1997-08-01 00:00:00
abstract:BACKGROUND:Though acral lentiginous melanoma (ALM) is a major type of malignant melanoma, no immunohistochemical study on this type of melanoma has been reported. OBJECTIVE:The purpose of this study is to analysis the immunohistochemical findings of ALM using routinely used immune markers. METHODS:An immunohistochemi...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2003.01583.x
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:Dermatofibrosarcoma protuberans (DFSP) is an uncommon malignant tumor of the skin, the diagnosis of which can be difficult not only clinically but also histologically. The tumor has a low metastatic potential, but tends to recur locally if removal is incomplete. METHODS:We reviewed the clinical and histolog...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1995.tb01591.x
更新日期:1995-04-01 00:00:00
abstract:BACKGROUND:Venous ulcer is the most serious consequence of chronic venous insufficiency and is responsible for almost 70% of chronic leg ulcers. The main purpose of this research was to describe social, demographic and clinical characteristics of patients with venous ulcers and to identify some professional repercussio...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02276.x
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:The use of lasers is very common in dermatology; however, many patients fear it and have various misconceptions about it. A literature search failed to show any studies on this topic. OBJECTIVE:To explore the various misconceptions of patients about lasers in dermatology. METHODS:A self-administered questi...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.05028.x
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:This study sought to gain a better understanding of the patient population in Kampala and was further designed to elucidate barriers that may delay individuals from receiving proper dermatologic care. METHODS:The study took place at the dermatovenereology clinic of a tertiary care hospital in Kampala. New a...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.13435
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:The rate of human immunodeficiency virus (HIV) infection in women of reproductive age has increased dramatically in the last decade. The effects of pregnancy on the prevalence of cutaneous diseases in this group is unclear. OBJECTIVES:To compare the prevalence of cutaneous diseases in healthy pregnant women...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2003.01776.x
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Castleman disease (CD) is a lymphoproliferative B-cell disease that is diagnosed from lymphoid hyperplasia with vascular proliferation. Symptoms may include fever, night sweats, and weight loss. Cutaneous manifestations often may go unnoticed since little has been described in the literature regarding them. ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.15043
更新日期:2020-10-01 00:00:00
abstract::A 23-year-old man with AIDS developed a lesion with the clinical characteristics of an ectopic geographic tongue in the lower lip, near the right commissure. ...
journal_title:International journal of dermatology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-4362.1990.tb04080.x
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:Acne vulgaris is a common skin disease affecting more than 85% of adolescents and often continuing into adulthood. Population-based studies to assess the patterns and severity of acne have not been achieved. OBJECTIVES:The aim of this study was to assess the most common patterns of facial and trunk acne in ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2011.05333.x
更新日期:2013-05-01 00:00:00
abstract::An 11-month-old male infant was referred to our clinic because of a painful ulcer of approximately 5 months' duration on the ventral surface of the tongue (Fig. 1). On physical examination, the lesion was circular (3 cm x 2 cm) with erythematous, raised, and indurated borders. No pathologic findings emerged from the l...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4632.2004.02554.x
更新日期:2006-09-01 00:00:00
abstract::To date, various treatment modalities have failed to produce consistent improvement in patients having Behçet's disease. Recent reports in the literature, however, have shown promising results with the use of colchicine. Our patient, an 18-year-old white woman, satisfied the 1977 Istanbul Conference criteria for Behçe...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/j.1365-4362.1982.tb01202.x
更新日期:1982-11-01 00:00:00
abstract:BACKGROUND:CD4+ CD25+ T-regulatory (Treg) cells play critical roles in maintaining peripheral tolerance and preventing autoimmunity. As characteristics of Treg cells have not been precisely investigated in chronic urticaria (CU) yet, this study was performed. OBJECTIVE:To determine the frequencies of circulating CD4+ ...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.12630
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Common treatment of atrophic acne scars consists of invasive methods such as dermabrasion, chemopeeling, or implantation of bovine collagen. In our study a new noninvasive treatment method consisting of local iontophoresis is demonstrated. Local iontophoresis was performed with either estriol--a mainly topic...
journal_title:International journal of dermatology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-4362.1995.tb04381.x
更新日期:1995-01-01 00:00:00
abstract::Hyperbaric oxygen therapy (HBOT) appears to enhance wound healing, increase bactericidal activity, and act synergistically with a number of antibiotics. The aim of this study was to evaluate the efficacy of HBOT as an adjunctive therapy in patients with hidradenitis suppurativa (HS) treated with a combination of syste...
journal_title:International journal of dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1111/ijd.12936
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Ant sting reactions are becoming an increasing problem in tropical countries. It is important for physicians to be aware of their possible cutaneous and systemic manifestations. METHODS:A child with a severe allergic reaction to an ant sting was examined and is discussed. This is the first case described in...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1046/j.1365-4362.2002.01480.x
更新日期:2002-11-01 00:00:00
abstract:BACKGROUND:Prompt management of acute graft-versus-host disease (GVHD) may prevent its morbidity and mortality. Maculopapular (MP) eruption is a presenting sign of acute GVHD, but differentiation from other causes of MP rash is challenging. METHODS:A retrospective study was conducted among patients developing MP erupt...
journal_title:International journal of dermatology
pub_type: 杂志文章
doi:10.1111/ijd.15186
更新日期:2021-01-01 00:00:00