Nd:YAG laser for "fractional" treatment of angiofibromas.

Abstract:

BACKGROUND:Tuberous sclerosis is an autosomal dominant disorder with hamartomas in multiple organ systems. Facial angiofibromas (AF) are a common cutaneous manifestation of tuberous sclerosis. They may lead to significant cosmetic and psychological problems. Many treatment modalities have been used with variable satisfaction. Fractional photothermolysis (FP) is a novel concept of laser therapy, which induces non-contiguous microscopic thermal injury. OBJECTIVE:This study was designed to evaluate the efficacy and side effects of Nd:YAG laser treatment for facial AF by using spot-like irradiation technique similar to FP. MATERIALS AND METHODS:Twelve patients (skin types III-IV, aged 17-45 years) with facial AF received monthly treatment with Nd:YAG laser in a pinpoint coagulation fashion. Clinical improvements were evaluated in five categories. Side effects were monitored at each follow-up visit. RESULTS:Excellent improvement was seen in 10 patients and good improvement in two at one month after the final treatment session. After 12 months of follow-up, no patient had significant recurrence of AF. Five patients were followed up for three years with few pinpoint-sized regrowth occurring; none of these patients received additional treatments. Side effects included transient erythema and edema in each patient but no bleeding, infection, dyspigmentation, or scarring. CONCLUSIONS:The present study indicates that Nd:YAG laser is an effective and safe management for the fractional treatment of facial AF.

journal_name

Int J Dermatol

authors

Ma G,Wu P,Lin X,Chen H,Li W,Hu X,Jin Y

doi

10.1111/ijd.12384

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

638-42

issue

5

eissn

0011-9059

issn

1365-4632

journal_volume

53

pub_type

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