Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study.

Abstract:

BACKGROUND:Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue-derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC-CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of alopecia using ADSC-CM. OBJECTIVES:This study evaluates our clinical experience in the use of ADSC-CM for the treatment of FPHL. METHODS:A retrospective, observational study of outcomes in 27 patients with FPHL treated with ADSC-CM was performed. To evaluate the efficacy of the treatment, patients' medical records and phototrichographic images were analyzed. RESULTS:The application of ADSC-CM showed efficacy in treating FPHL after 12 weeks of therapy. Hair density increased from 105.4 to 122.7 hairs/cm(2) (P < 0.001). Hair thickness increased from 57.5 μm to 64.0 μm (P < 0.001). None of the patients reported severe adverse reactions. CONCLUSIONS:The application of ADSC-CM is a potential treatment option for FPHL.

journal_name

Int J Dermatol

authors

Shin H,Ryu HH,Kwon O,Park BS,Jo SJ

doi

10.1111/ijd.12650

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

730-5

issue

6

eissn

0011-9059

issn

1365-4632

journal_volume

54

pub_type

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