当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Modification of glutamine synthetase in Streptomyces griseus by ADP-ribosylation and adenylylation.

Modification of glutamine synthetase in Streptomyces griseus by ADP-ribosylation and adenylylation.

Abstract：

:Addition of NH4+ to STreptomyces griseus 2682 cells grown in NO3- containing medium resulted in a rapid decline in glutamine synthetase activity due to covalent modification of the enzyme. The NH4+ promoted inactivation of the enzyme was inhibited by the ADP-ribosyltransferase inhibitor 3-methoxybenzamide. In the presence of ADP-ribosyltransferase activity the purified glutamine synthetase was also inhibited by NAD+ in a concentration-dependent manner. ADP-ribosylation of glutamine synthetase was demonstrated in vitro by showing the incorporation of labeled ADP-ribose from [alpha-32P]NAD+ into glutamine synthetase subunits. Beside ADP-ribosylation, adenylylation of glutamine synthetase was also shown in S. griseus since phosphodiesterase I treatment reactivated the enzyme in crude extracts of NH(4+)-shocked cells. Glutamine synthetase was also inhibited and modified by ATP in crude cellular extracts. These results suggest that in S. griseus 2682 ADP-ribosylation of glutamine synthetase could be an alternative modification to adenylylation to regulate glutamine synthetase activity.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Penyige A,Kálmánczhelyi A,Sipos A,Ensign JC,Barabás G

doi

10.1006/bbrc.1994.2501

subject

Has Abstract

pub_date

1994-10-28 00:00:00

pages

598-605

issue

2

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(84)72501-0

journal_volume

204

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Comparative studies of polyhemic cytochromes c isolated from Desulfovibrio vulgaris (Hildenborough) and Desulfovibrio desulfuricans (Norway).

    abstract：:Cytochrome c3 (Mr 26,000) has been characterized in Desulfovibrio vulgaris (Hildenborough) and its properties compared with polyhemic cytochromes c isolated from the same organism and from D. desulfuricans (Norway). It can be described as an octaheme cytochrome c3 constituted of two identical subunits. Absorption spec...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)90047-8

    authors： Loutfi M,Guerlesquin F,Bianco P,Haladjian J,Bruschi M

    更新日期：1989-03-15 00:00:00

  • Proteoglycan gene expression in rat liver after partial hepatectomy.

    abstract：:Liver regeneration is regulated by several factors. Among these extracellular matrix plays a crucial role in the restoration of normal structure. Proteoglycans are major components of extracellular matrix and they are able to bind growth factors implicated in liver growth. We studied syndecan, perlecan, fibroglycan, a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.1718

    authors： Gallai M,Sebestyén A,Nagy P,Kovalszky I,Onody T,Thorgeirsson SS

    更新日期：1996-11-21 00:00:00

  • Structures of the lamin A/C R335W and E347K mutants: implications for dilated cardiolaminopathies.

    abstract：:Dilated cardiomyopathy (DCM) is a condition whereby the normal muscular function of the myocardium is altered by specific or multiple aetiologies. About 25-35% of DCM patients show familial forms of the disease, with most mutations affecting genes encoding cytoskeletal proteins. Most of the DCM-related mutations fall ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.12.136

    authors： Bollati M,Barbiroli A,Favalli V,Arbustini E,Charron P,Bolognesi M

    更新日期：2012-02-10 00:00:00

  • The novel aldehyde dehydrogenase gene, ALDH5, encodes an active aldehyde dehydrogenase enzyme.

    abstract：:The mRNA for the novel aldehyde dehydrogenase 5 (ALDH5) gene was detected in HuH7 hepatoma cells. The cells also expressed cytosolic aldehyde dehydrogenase (ALDH1) mRNA, but no mitochondrial aldehyde dehydrogenase (ALDH2) mRNA. Extracts of the hepatoma cells contained an enzymatic activity with an isoelectric point si...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.1789

    authors： Stewart MJ,Malek K,Xiao Q,Dipple KM,Crabb DW

    更新日期：1995-06-06 00:00:00

  • Inhibition of myosin light chain kinase by amiloride.

    abstract：:Phosphorylation of regulatory light chain (LC20) by myosin light chain kinase (MLCK) has been thought to play an important role in both smooth muscle contraction and several functions of vertebrate non-muscle cells. Amiloride, a frequently used Na+/H+ exchange inhibitor, potently inhibited phosphorylation of LC20 by M...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)90808-5

    authors： Higashihara M

    更新日期：1989-08-15 00:00:00

  • High salt-diet reduces SLC14A1 gene expression in the choroid plexus of Dahl salt sensitive rats.

    abstract：:Elevated Na(+) concentration ([Na(+)]) in the cerebrospinal fluid (CSF) contributes to the development of salt-sensitive hypertension. CSF is formed by the choroid plexus (CP) in cerebral ventricles, and [Na(+)] in CSF is controlled by transporters in CP. Here, we examined the effect of high salt diet on the expressio...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.04.010

    authors： Guo L,Meng J,Xuan C,Ge J,Sun W,O'Rourke ST,Sun C

    更新日期：2015-05-29 00:00:00

  • NMR-based metabolite profiling of human milk: A pilot study of methods for investigating compositional changes during lactation.

    abstract：:Low-molecular-weight metabolites in human milk are gaining increasing interest in studies of infant nutrition. In the present study, the milk metabolome from a single mother was explored at different stages of lactation. Metabolites were extracted from sample aliquots using either methanol/water (MeOH/H2O) extraction ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.11.114

    authors： Wu J,Domellöf M,Zivkovic AM,Larsson G,Öhman A,Nording ML

    更新日期：2016-01-15 00:00:00

  • LincRNA TINCR facilitates excessive proliferation and inflammation in post-burn skin fibroblasts by directly binding with SND1 protein and inducing SND1-mediated TGF-β1 expression.

    abstract：:In this study, we found that lincRNA-TINCR was significantly upregulated in burn-injured skin tissues in vivo and heat-stimulated dermal fibroblasts in vitro, accompanied by an increase in TGF-β1 expression. TINCR overexpression promoted cell proliferation, colony formation, release of pro-inflammatory factors and exp...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.01.013

    authors： Qin G,Song Y,Guo Y,Sun Y,Zeng W

    更新日期：2019-02-19 00:00:00

  • Partial covalent labeling with pyridoxal 5'-phosphate induces bis(sulfosuccinimidyl)suberate crosslinking of band 3 protein tetramers in intact human red blood cells.

    abstract：:Partial covalent labeling of band 3 protein lysines with pyridoxal 5'-phosphate (a substrate and affinity probe) changes the bis(sulfosuccinimidyl)suberate crosslinking pattern of band 3 in intact red cells from a mixture of dimers and tetramers to all tetramers as the exclusive crosslinked product. This is the first ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)80762-9

    authors： Salhany JM,Sloan RL

    更新日期：1988-11-15 00:00:00

  • The importance of adenosine deaminase for lymphocyte development and function.

    abstract：:Deficiency in the enzyme adenosine deaminase (ADA) in humans manifests primarily as severe lymphopenia and immunodeficiency, resulting in death by 6 months of age, if untreated. In this review, we discuss phenotypical, biochemical, and metabolic hallmarks of the disease, and describe a mouse model in which levels of A...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章,评审

    doi：10.1006/bbrc.2000.2773

    authors： Aldrich MB,Blackburn MR,Kellems RE

    更新日期：2000-06-07 00:00:00

  • High glucose induced VEGF expression via PKC and ERK in glomerular podocytes.

    abstract：:Podocytes are the major site of vascular endothelial growth factor (VEGF) production in the kidney, and up-regulation of VEGF plays a critical role in the progression of diabetic nephropathy. Using a differentiated mouse podocyte cell line, we investigated the roles of protein kinase C (PKC) and extracellular signal-r...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.6138

    authors： Hoshi S,Nomoto K,Kuromitsu J,Tomari S,Nagata M

    更新日期：2002-01-11 00:00:00

  • NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli.

    abstract：:Using a novel approach for analysis of TRPC channel activity, we report here that NSAIDs are involved into regulation of TRPC channels in the podocytes of the freshly isolated decapsulated glomeruli. Fluorescence and electron microscopy techniques confirmed the integrity of podocytes in the glomeruli. Western blotting...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.04.005

    authors： Ilatovskaya DV,Levchenko V,Ryan RP,Cowley AW Jr,Staruschenko A

    更新日期：2011-05-06 00:00:00

  • Atorvastatin induces tissue transglutaminase in human endothelial cells.

    abstract：:Tissue transglutaminase (tTgase) contributes to the organisation of the basement membrane and is therefore thought to be important for the integrity and stability of the vessel wall. In the present study, we hypothesised that the HMG-CoA reductase inhibitor atorvastatin may up-regulate the tTgase expression in endothe...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.07.087

    authors： Soehnlein O,Eskafi S,Schmeisser A,Kloos H,Daniel WG,Garlichs CD

    更新日期：2004-09-10 00:00:00

  • DNA triple helix stabilization by bisguanidinyl analogues of biogenic polyamines.

    abstract：:The polycationic nature of biogenic polyamines such as spermine (SPM, 1) and spermidine (SPD, 2) plays an important role in selective binding to polyanionic nucleic acids. These interactions are mediated by electrostatic and hydrogen bonding forces which led to stabilization of DNA duplexes and triplexes. Transformati...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.0759

    authors： Pallan PS,Ganesh KN

    更新日期：1996-05-15 00:00:00

  • The binding of N-(phosphonacetyl)-L-aspartate to aspartate carbamoyltransferase of Escherichia coli.

    abstract：:A more precise description of the binding of N-(phosphonacetyl)-L- aspartate to the catalytic chains of aspartate carbamoyltransferase clarifies aspects of the specificity of this enzyme toward its substrates, carbamoylphosphate and L-aspartate, and suggests a catalytic role for His-134. ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(86)90514-0

    authors： Volź KW,Krause KL,Lipscomb WN

    更新日期：1986-04-29 00:00:00

  • Effect of naturally occurring mutations in human glycine N-methyltransferase on activity and conformation.

    abstract：:Missense mutations in the enzyme, glycine N-methyltransferase (GNMT) have been shown to be one cause of persistent isolated hypermethioninaemia in humans. These mutations were first identified by metabolite analysis and were shown to be L49P, N140S, and H176N by gene sequencing. Here we report the kinetic and conforma...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2003.11.037

    authors： Luka Z,Wagner C

    更新日期：2003-12-26 00:00:00

  • A role for DIS3L2 over natural nonsense-mediated mRNA decay targets in human cells.

    abstract：:The nonsense-mediated decay (NMD) pathway selectively degrades mRNAs carrying a premature translation-termination codon but also regulates the abundance of a large number of physiological mRNAs that encode full-length proteins. In human cells, NMD-targeted mRNAs are degraded by endonucleolytic cleavage and exonucleoly...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.08.105

    authors： da Costa PJ,Menezes J,Saramago M,García-Moreno JF,Santos HA,Gama-Carvalho M,Arraiano CM,Viegas SC,Romão L

    更新日期：2019-10-22 00:00:00

  • Ancient DNA in human bone remains from Pompeii archaeological site.

    abstract：:aDNA extraction and amplification procedures have been optimized for Pompeian human bone remains whose diagenesis has been determined by histological analysis. Single copy genes amplification (X and Y amelogenin loci and Y specific alphoid repeat sequences) have been performed and compared with anthropometric data on ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.8881

    authors： Cipollaro M,Di Bernardo G,Galano G,Galderisi U,Guarino F,Angelini F,Cascino A

    更新日期：1998-06-29 00:00:00

  • Identification and comparison of long non-conding RNA in Jinhua and Landrace pigs.

    abstract：:The regulatory role of long non-coding RNAs (lncRNAs) in various biological functions has been demonstrated. However, their role in fat deposition and lipid metabolism in pigs remains less understood. To explore the expression profile of lncRNAs in Jinhua and Landrace pigs, we investigated the expression levels of lnc...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.06.028

    authors： Miao Z,Wang S,Zhang J,Wei P,Guo L,Liu D,Wang Y,Shi M

    更新日期：2018-11-30 00:00:00

  • Cloning of SEZ-12 encoding seizure-related and membrane-bound adhesion protein.

    abstract：:SEZ-12 is one of the seizure-related cDNAs which was isolated by differential hybridization from primary cultured neurons from the mouse cerebral cortex with or without pentylenetetrazol (PTZ). SEZ-12 expression is transiently down-regulated in the mouse brain by injection of PTZ. To characterize SEZ-12, isolation of ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.0712

    authors： Kajiwara K,Nagasawa H,Shimizu-Nishikawa K,Ookura T,Kimura M,Sugaya E

    更新日期：1996-05-06 00:00:00

  • Autoregulation of bone sialoprotein gene in pre-osteoblastic and non-osteoblastic cells.

    abstract：:Regulation of the bone sialoprotein (BSP) gene is important in the differentiation of osteoblasts, in bone matrix mineralization, and in tumor metastasis. We investigated BSP gene transcription by performing functional analysis of the 9256bp of the 5' flanking region of the murine BSP gene containing its promoter. We ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.02.068

    authors： Tu Q,Yamauchi M,Pageau SC,Chen JJ

    更新日期：2004-04-02 00:00:00

  • Cleavage of cottontail rabbit papillomavirus E7 RNA with an anti-E7 ribozyme.

    abstract：:We have designed and constructed a plasmid (pE7RZ-1) that contains a gene for a hammerhead ribozyme that specifically cleaves cottontail rabbit papillomavirus (CRPV) E7 RNA sequences in vitro. The in vitro produced transcripts of pE7RZ-1 cleave CRPV E7 target sequences in trans at 37 degrees C. Pretreatment of pE7RZ-1...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1993.1490

    authors： Wisotzkey JD,Krizenoskas A,DiAngelo S,Kreider JW

    更新日期：1993-04-30 00:00:00

  • Small-angle X-ray scattering study by synchrotron orbital radiation reveals that high molecular weight subunit of glutenin is a very anisotropic molecule.

    abstract：:Small-angle X-ray scattering of one high molecular weight (HMW) subunit of wheat glutenin was measured at protein concentration ranges from 1.0 to 10.0 mg/ml. The radius of gyration of whole particles, RO, in aq. 50% (v/v) 1-propanol and 0.1M acetic acid was 16.6 +/- 0.1nm and 22.8nm, respectively, and the correspondi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(92)90854-e

    authors： Matsushima N,Danno G,Sasaki N,Izumi Y

    更新日期：1992-07-31 00:00:00

  • M-CSF receptor mutations in hereditary diffuse leukoencephalopathy with spheroids impair not only kinase activity but also surface expression.

    abstract：:The tyrosine kinase Fms, the cell surface receptor for M-CSF and IL-34, is critical for microglial proliferation and differentiation in the brain. Recently, a number of mutations have been identified in Fms as a putative genetic cause of hereditary diffuse leukoencephalopathy with spheroids (HDLS), implying an importa...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2013.09.141

    authors： Hiyoshi M,Hashimoto M,Yukihara M,Bhuyan F,Suzu S

    更新日期：2013-11-01 00:00:00

  • Bone morphogenetic protein.

    abstract：:Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the transforming growth factor-beta superfamily. It has been demonstrated that BMPs had been involved in the regulation of cell proliferation, survival, differentiation and apoptosis. However, their hallmark ability is that play a pivo...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章,评审

    doi：10.1016/j.bbrc.2007.08.045

    authors： Xiao YT,Xiang LX,Shao JZ

    更新日期：2007-10-26 00:00:00

  • Smad3 contributes to positioning of proliferating cells in colonic crypts by inducing EphB receptor protein expression.

    abstract：:Deficiency of Smad3, an intracellular mediator of TGF-β, was shown to significantly accelerate re-epithelialization of the colonic mucosa. This study was performed to investigate the molecular mechanisms by which Smad3 controls colonic epithelial cell proliferation and crypt formation. Smad3(ex8/ex8) C57BL/6 mice were...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.01.045

    authors： Furukawa K,Sato T,Katsuno T,Nakagawa T,Noguchi Y,Tokumasa A,Yokote K,Yokosuka O,Saito Y

    更新日期：2011-02-25 00:00:00

  • Amyloid beta peptide (Abeta42) activates PLC-delta1 promoter through the NF-kappaB binding site.

    abstract：:The abnormal deposition of amyloid beta peptide (Abeta) is a hallmark of Alzheimer's disease (AD). Phospholipase C-delta1 (PLC-delta1) is also known to abnormally accumulate in the brains of AD patients, but no report has addressed the relationship between these two events. This study investigated the effect of Abeta4...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2003.09.100

    authors： Kim JY,Kim H,Lee SG,Choi BH,Kim YH,Huh PW,Lee KH,Han H,Rha HK

    更新日期：2003-10-24 00:00:00

  • Tissue-specific roles of GCN2 in aging and autosomal dominant retinitis pigmentosa.

    abstract：:The organisms have the capacity to sense and adapt to their surroundings for their life in a dynamic environment. In response to amino acid starvation, cells activate a rectifying physiological program, termed the integrated stress response (ISR), to restore cellular homeostasis. General controlled non-repressed (GCN2...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2020.09.120

    authors： Kim K,Park JE,Yeom J,Park N,Trần TT,Kang MJ

    更新日期：2020-12-17 00:00:00

  • Mannoproteins from Saccharomyces cerevisiae stimulate angiogenesis by promoting the akt-eNOS signaling pathway in endothelial cells.

    abstract：:Mannoproteins (MPs) are a major component of yeast cell walls and consist of high levels of mannose in covalent complexes with proteins. MPs complexly enhance the immune system. We previously isolated a mutant yeast, K48L3, with a higher yield of MP from its cell wall than wild-type Saccharomyces cerevisiae, YPH499. W...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.09.069

    authors： Yoon BH,Lee SM,Chang HI,Ha CH

    更新日期：2019-11-19 00:00:00

  • Linkage exclusion analysis of two important chromosomal regions for height.

    abstract：:Adult height (stature), as an important parameter of human physical development, has been studied in many populations. Recently, we reported a whole genome scan of height on a sample of 630 Caucasian subjects from 53 human pedigrees. Two chromosome regions, 6q24-25 and 7q31.3-36, achieved low linkage signals (multipoi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.08.027

    authors： Yang YJ,Liu YZ,Li MX,Lei SF,Chen XD,Sun X,Deng HW

    更新日期：2005-10-07 00:00:00