Abstract:
:Review of problematic melanocytic consultation cases has enabled identification of the most common variants of benign melanocytic proliferations which can be confused with melanoma. Apart from Spitz naevus, the most common in this group of lesions are pigmented spindle cell naevus and atypical dermal nodule. Potentially the most problematic but less common are pseudomelanoma following incomplete removal of a naevus and 'activated' benign naevus cells in sentinel lymph nodes. By considering the overall architecture and the degree of nuclear atypia of the lesions, all of these problems can usually be resolved. Nuclear or architectural abnormalities by themselves are insufficient and must be assessed together. In addition, the combinations of pattern and cytological change in most of the lesions described here are distinctive and have become recognised as known variations of benign entities.
journal_name
Pathologyjournal_title
Pathologyauthors
Cook MGdoi
10.1080/00313020412331283842subject
Has Abstractpub_date
2004-10-01 00:00:00pages
414-8issue
5eissn
0031-3025issn
1465-3931pii
QBMDV146E2LQ2XATjournal_volume
36pub_type
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