The pathological assessment of ovarian neoplasms. II: The proliferating 'epithelial' tumours.

abstract：:We aimed to evaluate the diagnostic utility of the novel immunohistochemical marker TROP-2 on thyroid specimens (226 tumours and 207 controls). Whole slide immunohistochemistry was performed and scored by automated digital image analysis. Non-neoplastic thyroid, follicular adenomas, follicular carcinomas, and medullar...

journal_title：Pathology

authors： Bychkov A,Sampatanukul P,Shuangshoti S,Keelawat S

更新日期：2016-08-01 00:00:00

abstract：:The 2005 International Society of Urological Pathology (ISUP) modified Gleason grading system was further amended in 2014 with the establishment of grade groupings (ISUP grading). This study examined the predictive value of ISUP grading, comparing results with recognised prognostic parameters.Of 3700 men undergoing ra...

journal_title：Pathology

authors： Samaratunga H,Delahunt B,Gianduzzo T,Coughlin G,Duffy D,LeFevre I,Johannsen S,Egevad L,Yaxley J

更新日期：2015-10-01 00:00:00

abstract：AIMS:To investigate the evolutionary origins of Australian healthcare-associated (HCA) methicillin-resistant Staphylococcus aureus (MRSA) strains from a panel of historical isolates typed using current genotyping techniques. METHODS:Nineteen MRSA isolates from 1965 to 1981 were examined and antibiotic susceptibility p...

journal_title：Pathology

authors： Lancashire JF,Jones A,Bergh H,Huygens F,Nimmo GR

更新日期：2013-08-01 00:00:00

abstract：:Renal cell carcinoma (RCC) generally has a poor prognosis because of late diagnosis and metastasis. We have previously described decreased tumour necrosis factor receptor-associated factor-1 (TRAF-1) in RCC compared with paired normal kidney in a patient cohort in Australia. In the present study, TRAF-1 expression in ...

journal_title：Pathology

authors： Rajandram R,Yap NY,Pailoor J,Razack AH,Ng KL,Ong TA,Morais C,Gobe GC

更新日期：2014-10-01 00:00:00

abstract：:Sex cord-stromal tumours (SCSTs) consist of a heterogeneous group of neoplasms with diverse clinicopathological features and biological behaviour. They often present as a diagnostic challenge as they have varied and occasionally overlapping histomorphology and some may even mimic non-SCSTs. An accurate diagnosis is im...

journal_title：Pathology

authors： Lim D,Oliva E

更新日期：2018-02-01 00:00:00

abstract：AIM:Lignocaine, a topical anaesthetic agent, is generally used in variable concentrations usually between 2% and 4% on the vocal cords prior to flexible bronchoscopy and bronchoalveolar lavage (BAL) procedures. The aim of this study was to investigate whether 2% or 1% lignocaine significantly inhibits the growth of org...

journal_title：Pathology

authors： Chandan SS,Faoagali J,Wainwright CE

更新日期：2005-08-01 00:00:00

abstract：:Tumor cell-platelet interactions have been shown to be involved in the process of metastasis. This study characterizes the aggregation of washed platelets induced by the human uterine carcinosarcoma Colo 526. Ultrastructural studies revealed a two-stage process in which the earliest events were the adhesion and degran...

journal_title：Pathology

authors： Bradley CJ,Dauer RJ,Thurlow PJ,Connellan JM

更新日期：1997-05-01 00:00:00

abstract：:Colonic mucosal biopsies from patients with melanosis coli were examined by electron microscopy. They showed apoptosis of colonic surface epithelial cells and phagocytosis of resulting apoptotic bodies by intraepithelial macrophages. The latter migrated to the lamina propria where intracellular degradation of the apop...

journal_title：Pathology

authors： Walker NI,Smith MM,Smithers BM

更新日期：1993-04-01 00:00:00

abstract：:The morphology of livers of Wistar rats treated with beta-carotene (BC), vitamin A (VA, retinol acetate) or corn oil (CO, controls) and submitted to the resistant hepatocyte model of carcinogenesis was studied. Preneoplastic lesions (PNL) were smaller and less numerous in the BC group. The latter group also presented ...

journal_title：Pathology

authors： Dagli ML,Guerra JL,Sinhorini IL,Wu TS,Rizzi MB,Penteado MV,Moreno FS

更新日期：1998-08-01 00:00:00

abstract：:Since its first description in the early part of the twentieth century, struma ovarii has elicited considerable interest because of its many unique features; however, at present a number of aspects remain enigmatic. Although the typical presentation is that of a pelvic mass, unusual clinical manifestations such as hyp...

journal_title：Pathology

authors： Roth LM,Talerman A

更新日期：2007-02-01 00:00:00

abstract：:Monoclonal antibodies have been raised against components of glomerular immune deposits in experimental glomerulonephritis and idiopathic human glomerulonephritis. An accelerated model of chronic serum sickness in the rat using cationized human serum albumin was employed to obtain renal tissue with capillary loop and ...

journal_title：Pathology

authors： Murphy BF,d'Apice AJ

更新日期：1988-04-01 00:00:00

abstract：:Epigenetic regulation is emerging as a critical mechanism for pancreatic ductal adenocarcinoma (PDA) development. Histone methylation is an important regulatory mechanism, altering chromatin structure and promoter accessibility and causing aberrant gene expression. NSD1 and SETD2 genes encoding two histone H3K36 methy...

journal_title：Pathology

authors： Ettel M,Zhao L,Schechter S,Shi J

更新日期：2019-06-01 00:00:00

abstract：AIMS:BRAF mutation has been shown in a large meta-analysis to be an independent prognostic marker for papillary thyroid carcinoma (PTC) with poorer survival and higher recurrence rates. METHODS:We studied prevalence of BRAF mutation in 77 patients with PTC from an Australian cohort using competitive polymerase chain r...

journal_title：Pathology

authors： McKelvie PA,Chan F,Yu Y,Waring P,Gresshoff I,Farrell S,Williams RA

更新日期：2013-12-01 00:00:00

abstract：:A 36-yr-old female with a 20-yr history of fibrodysplasia ossificans progressiva (FOP) died as the result of ruptured gastric ulcers. The patient had been treated with disodium ethane-l-hydroxy-1, 1-diphosphonate (EHDP). Post mortem there was thickening of the aortic valve cusps and mitral valve leaflets as well as sh...

journal_title：Pathology

authors： Jaworski RC,Gibson M

更新日期：1983-07-01 00:00:00

abstract：:A 14 yr old girl presented with a large cystic mass in the transverse mesocolon which was completely excised. Cystic lymphangioma was diagnosed, based on the specific histologic, immunoperoxidase and ultrastructural findings. ...

journal_title：Pathology

authors： Yuen ST,Ng IO,Ho J,Ma L

更新日期：1992-07-01 00:00:00

abstract：:Lymphadenopathy associated with hemorrhage as a presenting feature of primary (AL) amyloidosis has not previously been described. We report two such cases one of whom had an acquired factor X and IX deficiency. The clinical presentations were characterized by sudden spontaneous enlargement of lymph nodes followed by p...

journal_title：Pathology

authors： Hanley JP,MacLean FR,Evans JL,Colls BM,Robinson BA,Patton WN,Heaton DC

更新日期：2000-02-01 00:00:00

abstract：:HLA-B27 is a risk marker for ankylosing spondylitis and other associated seronegative spondyloarthropathies. We compared three methods of HLA-B*27 typing in a New South Wales (NSW) population: flow cytometry, rs4349859 single nucleotide polymorphism (SNP) detection assay, and allele-specific real-time polymerase chain...

journal_title：Pathology

authors： Jang HS,Proos A,Koe L,Anderson J,Fulton R,Fernando SL

更新日期：2020-02-01 00:00:00

abstract：:Since 1967 the Royal College of Pathologists of Australasia has been providing an external quality assurance programme in microbiology. The number of participants has risen from 70 to 222, and the samples distributed for investigation have increased in quantity, now totalling 35-40 per annum, and in variety, so that m...

journal_title：Pathology

authors： Ackerman VP,Pritchard RC

更新日期：1984-07-01 00:00:00

abstract：:Five cases of intraductal papillary-mucinous neoplasm (IPMN) of the pancreas are here described. This group of tumors represents a distinct clinicopathological entity with characteristic endoscopic, radiological, gross and microscopic appearances. Our five cases all showed marked dilatation of the main pancreatic duct...

journal_title：Pathology

authors： Kench JG,Eckstein RP,Smith RC

更新日期：1997-02-01 00:00:00

abstract：:A patient with cerebral strokes had a cardiac tumour excised. Histologically, it was an infarcted myxoma with features of a Gamna body. Findings are compared with other cardiac Gamna bodies reported in the literature. Most probably represent unusual degenerative changes in a myxoma. ...

journal_title：Pathology

authors： Coard KC,Silver MD

更新日期：1984-10-01 00:00:00

abstract：:The intimal thickness of the coronary arteries of humans less than 20 years of age was compared with that 9 other species. It was found that humans were unique amongst the species studied in showing substantial intimal thickening at an early age. The intimal thickening was associated with defects of the internal elast...

journal_title：Pathology

authors： Sims FH

更新日期：1989-04-01 00:00:00

abstract：:The lupus anticoagulant (LA) phenomenon created world-wide interest recently. Various tests have been devised to identify LA in plasma, but none of these methods have been universally accepted. In this study 16 cases labelled LA positive by a prior kaolin clotting time (KCT) test were reassessed by four other methods,...

journal_title：Pathology

authors： Stark RA,Gordon S

更新日期：1990-04-01 00:00:00

abstract：:The cell surface markers of 75 cases of non-Hodgkin's lymphoma were studied on cryostat sections using a panel of monoclonal antibodies. Forty-nine cases (65.3%) were found to express a B-cell phenotype, 23 cases (30.7%) a T-cell phenotype, 1 case (1.3%) a histiocytic phenotype and 2 cases (2.7%) no demonstrable surfa...

journal_title：Pathology

authors： Ng CS,Chan JK,Lo ST,Poon YF

更新日期：1986-10-01 00:00:00

abstract：AIMS:To assess the production of a liver-specific protein, albumin, and of a master transcriptional factor, hepatocyte nuclear factor (HNF)-4alpha, in hepatoid adenocarcinoma tissue. METHODS:Standard and quantitative RT-PCR, using five cases of hepatoid and three cases of non-hepatoid gastric adenocarcinoma. RESULTS:...

journal_title：Pathology

authors： Yano T,Kishimoto T,Tomaru U,Kawarada Y,Kato H,Yoshiki T,Ishikura H

更新日期：2003-02-01 00:00:00

abstract：AIMS:Sirtuin1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent deacetylase. Recently, some studies have suggested that SIRT1 could be over-expressed in breast, prostate and colon cancers and up-regulated SIRT1 inactivates p53 by deacetylation. Therefore, we investigated the prevalence and the prognostic impact ...

journal_title：Pathology

authors： Jang KY,Kim KS,Hwang SH,Kwon KS,Kim KR,Park HS,Park BH,Chung MJ,Kang MJ,Lee DG,Moon WS

更新日期：2009-01-01 00:00:00

abstract：:The recent upsurge in the association of congenital neurological disorders and infection by the Zika virus (ZIKV) has resulted in increased research focus on the biology of this flavivirus. Studies in animal models indicate that ZIKV can breach the placental barrier and selectively infect and deplete neuroprogenitor c...

journal_title：Pathology

authors： Gharbaran R,Somenarain L

更新日期：2017-12-01 00:00:00

abstract：AIM:Performance measures for Australian laboratories reporting cervical cytology are a set of quantifiable measures relating to the profile and accuracy of reporting. This study reviews aggregate data collected over the ten years in which participation in the performance measures has been mandatory. METHODS:Laboratori...

journal_title：Pathology

authors： Shield PW,Finnimore J,Cummings M,Wright RG

更新日期：2010-12-01 00:00:00

abstract：:The pathological findings in a retrospective review of 100 consecutive intracranial stereotactic biopsies are presented. Definite diagnosis could be established in the majority (89) of cases and included 85 neoplasms (69 primary cerebral tumors, 10 non-Hodgkin's lymphomas and 6 metastases) and 4 non-neoplastic process...

journal_title：Pathology

authors： Robbins PD,Yu LL,Lee M,Stokes BA,Thomas GW,Watson P,Wong G

更新日期：1994-10-01 00:00:00

abstract：:Distinct differences in the extent and progression of the lateral and epicardial boundaries of evolving regional infarcts were demonstrated in isolated rabbit hearts. Ischemia was produced by interrupting (0-240 minutes) flow in the ventral interventricular branch of the left coronary artery, whilst the remainder of t...

journal_title：Pathology

authors： Sage MD,Gavin JB

更新日期：1985-10-01 00:00:00

abstract：:The sections in the following review cover six main neurodegenerative diseases. The first article on Alzheimer's disease (AD) outlines the major evidence available to date that links Aβ-amyloid peptide as a proximal cause of AD. The article also highlights how an initial finding of the protein content of the amyloid p...

journal_title：Pathology

authors： Masters CL,Kril JJ,Halliday GM,Pamphlett R,Collins S,Hill AF,McLean C

更新日期：2011-02-01 00:00:00