Identification of the components of glomerular immune deposits using monoclonal antibodies.

abstract：:Murine monoclonal antibodies to human myeloid cell surface differentiation antigens were prepared using the myelomonocytic leukemia cell line RC-2A as immunogen. Using a highly sensitive colorimetric assay, antibodies were selected as myeloid-associated based on their binding to RC-2A cells, but not to cells of the au...

journal_title：Pathology

authors： Lyons AB,Cooper SJ,Cole SR,Ashman LK

更新日期：1988-04-01 00:00:00

abstract：:The case is reported of a woman aged 60 yrs who presented with systemic symptoms and who was found to have proteinuria of 3.5 g per day. A renal biopsy revealed numerous neoplastic cells filling many of the glomerular capillary lumina. Immunoperoxidase stains revealed that the phenotype of the malignant cells was LCA+...

journal_title：Pathology

authors： Axelsen RA,Laird PP,Horn M

更新日期：1991-07-01 00:00:00

abstract：:Epithelial ovarian neoplasms can be divided into three distinct clinicopathological groups: benign, malignant and borderline tumours. Borderline tumours are less aggressive than epithelial carcinomas, with an indolent clinical course and delayed recurrence. However, a subset of these cases can progress to malignancy a...

journal_title：Pathology

authors： Losi L,Botticelli L,Garagnani L,Fabbiani L,Panini R,Gallo G,Sabbatini R,Maiorana A,Benhattar J

更新日期：2021-02-01 00:00:00

abstract：AIMS:To investigate the evolutionary origins of Australian healthcare-associated (HCA) methicillin-resistant Staphylococcus aureus (MRSA) strains from a panel of historical isolates typed using current genotyping techniques. METHODS:Nineteen MRSA isolates from 1965 to 1981 were examined and antibiotic susceptibility p...

journal_title：Pathology

authors： Lancashire JF,Jones A,Bergh H,Huygens F,Nimmo GR

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Digital papillary adenocarcinoma (DPA) is a rare malignant adnexal tumour that occurs almost exclusively in a digital location. Only two case series have been reported previously. AIMS:To document the clinical and histopathological findings in a series of patients with DPA. RESULTS:Of the 8 patients identi...

journal_title：Pathology

authors： Scolyer RA,Karim RZ,Thompson JF,Stretch JR,McCarthy SW,Murali R

更新日期：2013-01-01 00:00:00

abstract：:A calcified nodule on the liver of a 62-year-old man from North Carolina, USA, contained a degenerated nymph of Linguatula serrata. The nodule was incidentally discovered at laparotomy for malignant lymphoma and cholelithiasis. The cuticle was all that remained of the parasite, but sclerotized openings and large spine...

journal_title：Pathology

authors： Baird JK,Kassebaum LJ,Ludwig GK

更新日期：1988-04-01 00:00:00

abstract：AIMS:Mixed type liposarcomas are rare. Here, we analysed the characteristics of an unusual case of mixed type liposarcoma, which consisted of a well-differentiated liposarcoma (WDL) and a pleomorphic liposarcoma (PL), with a special emphasis on molecular alterations. METHODS:Microscopic and immunohistochemical approac...

journal_title：Pathology

authors： Kim JI,Choi KU,Lee IS,Moon TY,Lee CH,Kim HW,Kim JY,Park DY,Sol MY

更新日期：2006-04-01 00:00:00

abstract：:The coexistence of a pancreatic papillary cystic tumor with hairy cell leukemia is reported. To the best of our knowledge this association has never been published. A 41-year-old man diagnosed with hairy cell leukemia developed a second malignancy that corresponded to a papillary cystic pancreatic tumor. The patient u...

journal_title：Pathology

authors： Acebo E,Rodilla IG,Torío B,Hernando M,García de Polavieja M,Morales D,Seco I,Bermudez A

更新日期：2000-08-01 00:00:00

abstract：:Antibodies that bind phospholipid (anti-phospholipid antibodies [APA]) are a focus of major interest to both clinical and laboratory personnel across a variety of disciplines because of the assortment of disorders with which they are reportedly associated. A solid phase assay using cardiolipin as the test phospholipid...

journal_title：Pathology

authors： Favaloro EJ,Silvestrini R,Mohammed A

更新日期：1999-05-01 00:00:00

abstract：:While localised prostate cancer can be cured by local treatment, 'high-risk' prostate cancer often progresses to castration resistant disease and remains incurable with a dismal prognosis. In recent years, technical advances and development of novel methodologies have largely contributed to a better understanding of u...

journal_title：Pathology

authors： Vlajnic T,Bubendorf L

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Detection of the V600E hotspot mutation in BRAF oncogene is extremely useful for the screening of hereditary non-polyposis colorectal cancer (Lynch's syndrome) and for the prediction of sensitivity to MEK inhibitors. Here we describe a method for detecting this mutation based upon pyrosequencing technology...

journal_title：Pathology

authors： Tan YH,Liu Y,Eu KW,Ang PW,Li WQ,Salto-Tellez M,Iacopetta B,Soong R

更新日期：2008-04-01 00:00:00

abstract：:The alkaline phosphatase from neutrophils of pregnant women and normal males has been extracted, subjected to various inhibitory procedures and to electrophoresis. It is demonstrated that the iso-enzyme obtained from each group is indistinguishable from the skeletal iso-enzyme, in contrast to the serum iso-enzyme of p...

journal_title：Pathology

authors： Findlay AB,Johnston NG

更新日期：1977-01-01 00:00:00

abstract：:A case of solitary cervical intramedullary schwannoma with an extramedullary extension is reported. This case demonstrates the difficulty of radiologic diagnosis of these tumours and the necessity for pre-treatment biopsy. ...

journal_title：Pathology

authors： Garen PD,Collett MG,Harper CG

更新日期：1988-07-01 00:00:00

abstract：:The aim of this study was to establish the diagnostic utility of p53 immunohistochemistry in Barrett's esophagus. Three pathologists reviewed endoscopic biopsy specimens and one surgical specimen derived from 102 subjects in a prospective follow-up series. Dysplasia was graded as negative, indefinite, low grade and hi...

journal_title：Pathology

authors： Khan S,Do KA,Kuhnert P,Pillay SP,Papadimos D,Conrad R,Jass JR

更新日期：1998-05-01 00:00:00

abstract：:Changes in the contracture and stiffness of ventricular walls during ischemia and their effect on vascular reperfusion were studied in isolated rat hearts. Global ischemia was induced by stopping the flow of oxygenated perfusate for 60 min. Contracture pressures generated against water-filled left ventricular balloons...

journal_title：Pathology

authors： Humphrey SM,Gavin JB

更新日期：1985-07-01 00:00:00

abstract：:Lysosome-associated membrane protein-1 (LAMP1) has been suggested to play complicated roles in cancer development and metastasis. The aim of this study was to explore the expression of LAMP1 in laryngeal squamous cell carcinoma (LSCC) and investigate the relationship between LAMP1 expression and clinicopathological ch...

journal_title：Pathology

authors： Lu M,Zhu H,Wang X,Zhang D,Xiong L,Zhu J,Mao Y,Qiang J

更新日期：2016-12-01 00:00:00

abstract：:Seven cases of lower respiratory tract infection due to Corynebacterium pseudodiphtheriticum are described. Lower respiratory tract infections with C. pseudodiphtheriticum in immunocompetent patients are usually associated with pre-existing chronic pulmonary disease, and are sometimes associated with endotracheal intu...

journal_title：Pathology

authors： Freeman JD,Smith HJ,Haines HG,Hellyar AG

更新日期：1994-07-01 00:00:00

abstract：AIM:Hepcidin, a recently identified peptide, acts as a central regulator of iron metabolism. It is regarded as a factor regulating the uptake of dietary iron and its mobilisation from macrophages and hepatic stores. It is considered as a mediator of anaemia of inflammation. The aim of this study was to assess whether s...

journal_title：Pathology

authors： Jayaranee S,Sthaneshwar P,Sokkalingam S

更新日期：2009-02-01 00:00:00

abstract：:The values of a number of biochemical variables have been studied before and after a 50-gram load of glucose orally. Reductions which were statistically significant were found for sodium, potassium, urea, total protein, albumin, calcium, phosphorus, urate, bilirubin, alkaline phosphatase, but not for bicarbonate, crea...

journal_title：Pathology

authors： Masarei JR

更新日期：1977-01-01 00:00:00

abstract：:The early and late effects of wound healing on tumour development at a distant site were evaluated morphologically in an experimental model of colon carcinogenesis induced by 1,2-dimethylhydrazine (DMH). Random bred male Wistar rats were given subcutaneous injections of DMH (20 mg/kg) or saline, once a week, for eight...

journal_title：Pathology

authors： Sequeira JL,Kobayasi SS,Rodrigues MA

更新日期：2000-11-01 00:00:00

abstract：:The main controversy about nerve sheath tumors (NSTs) has been their histogenesis. A Schwann cell origin has been proposed by many investigators for both schwannomas and neurofibromas. However Erlandson and Woodruff observed that while schwannomas appeared to be composed predominantly of Schwann cells, neurofibromas c...

journal_title：Pathology

authors： Kharbanda K,Dinda AK,Sarkar C,Karak AK,Mathur M,Roy S

更新日期：1994-01-01 00:00:00

abstract：:We evaluated an immunoradiometric assay for serum TSH (IRMA-TSH) and compared it with established indices of thyroid function in 208 patients with either frank thyroid disease, conditions of abnormal thyroxine protein binding, or conditions which are known to produce discordant thyroid results, viz. pregnancy or estro...

journal_title：Pathology

authors： McLellan GH,Riley WJ,Summers MB,Sudholz P,Hickman PE

更新日期：1987-07-01 00:00:00

abstract：:Colonic mucosal biopsies from patients with melanosis coli were examined by electron microscopy. They showed apoptosis of colonic surface epithelial cells and phagocytosis of resulting apoptotic bodies by intraepithelial macrophages. The latter migrated to the lamina propria where intracellular degradation of the apop...

journal_title：Pathology

authors： Walker NI,Smith MM,Smithers BM

更新日期：1993-04-01 00:00:00

abstract：AIMS:CD151 belongs to the group of tetraspanins and is aberrantly expressed in different tumours and differential expression has been associated with prognosis. The aim of this study was to clarify the relationship of CD151 expression with tumour phenotype and clinical outcome in bladder cancer. METHODS:A bladder canc...

journal_title：Pathology

authors： Minner S,De Silva C,Rink M,Dahlem R,Chun F,Fisch M,Höppner W,Wagner W,Bokemeyer C,Terracciano L,Simon R,Sauter G,Wilczak W

更新日期：2012-08-01 00:00:00

abstract：:A retrospective study of gallbladders submitted as surgical specimens over a period of fifteen years (1972-1986) was performed in the Department of Pathology, Queen Mary Hospital, Hong Kong. Seven thousand nine hundred and ten gallbladders were examined. A total of 253 more unusual and significant pathological lesions...

journal_title：Pathology

authors： Chan KW

更新日期：1988-01-01 00:00:00

abstract：:HLA-B27 is a risk marker for ankylosing spondylitis and other associated seronegative spondyloarthropathies. We compared three methods of HLA-B*27 typing in a New South Wales (NSW) population: flow cytometry, rs4349859 single nucleotide polymorphism (SNP) detection assay, and allele-specific real-time polymerase chain...

journal_title：Pathology

authors： Jang HS,Proos A,Koe L,Anderson J,Fulton R,Fernando SL

更新日期：2020-02-01 00:00:00

abstract：AIMS:To examine the impact of microwave (MW) tissue processing on turnaround times (TATs) in a routine diagnostic laboratory. METHODS:A retrospective review of TATs for tissue processing (specimen receipt to completion of H&E-stained section) and pathologists' report generation (receipt of stained section to validatio...

journal_title：Pathology

authors： Leong AS,Price D

更新日期：2004-08-01 00:00:00

abstract：AIMS:Nuclear factor-kappa B (NF-kappaB) activation has been recognised as an important mechanism in the development of cancers. However, expression status of NF-kappaB-related proteins in oesophageal squamous cell carcinoma (ESCC) tissues is largely unknown. In this study, we analysed expressions of NF-kappaB members (...

journal_title：Pathology

authors： Kang MR,Kim MS,Kim SS,Ahn CH,Yoo NJ,Lee SH

更新日期：2009-01-01 00:00:00

abstract：:The intimal thickness of the coronary arteries of humans less than 20 years of age was compared with that 9 other species. It was found that humans were unique amongst the species studied in showing substantial intimal thickening at an early age. The intimal thickening was associated with defects of the internal elast...

journal_title：Pathology

authors： Sims FH

更新日期：1989-04-01 00:00:00

abstract：:We report a case of a 25-year-old man who presented with a large rectal bleed and positive Meckel's scan followed by surgical excision of a Meckel's diverticulum. The diverticulum was lined by gastric body type mucosa showing evidence of active chronic gastritis associated with the presence of Helicobacter pylori orga...

journal_title：Pathology

authors： Hill P,Rode J

更新日期：1998-02-01 00:00:00