Histochemical localization of acetylcholinesterase in the lateral eye and brain of Limulus polyphemus: might acetylcholine be a neurotransmitter for lateral inhibition in the lateral eye?

Abstract:

:The distribution of acetylcholinesterase (AChE) in the lateral eye and brain of the horseshoe crab was investigated with histochemical means using standard controls to eliminate butyrylcholinesterase and nonspecific staining. Intense staining was observed in the neural plexus of the lateral compound eye, in the lateral optic nerve, and in various neuropils of the brain. Nerve fibers with moderate to weak staining were widespread in the brain. No somata were stained in either the lateral eye or the brain. The distribution of acetylcholinesterase in the supraesophageal ganglia and nerves of the giant barnacle was also investigated for comparison. Although both the median optic nerve of the barnacle and the lateral optic nerve of the horseshoe crab appear to contain the fibers of histaminergic neurons, only the lateral optic nerve of the horseshoe crab shows AChE staining. Other parts of the barnacle nervous system, however, showed intense AChE staining. These results along with the histochemical controls eliminate the possibility that some molecule found in histaminergic neurons accounted for the AChE staining but support the possibility that acetylcholine might be involved as a neurotransmitter in lateral inhibition in the horseshoe crab retina. Two reasonable neurotransmitter candidates for lateral inhibition, histamine and acetylcholine, must now be investigated.

journal_name

Vis Neurosci

journal_title

Visual neuroscience

authors

Hornstein EP,Sambursky DL,Chamberlain SC

doi

10.1017/s0952523800003928

subject

Has Abstract

pub_date

1994-09-01 00:00:00

pages

989-1001

issue

5

eissn

0952-5238

issn

1469-8714

pii

S0952523800003928

journal_volume

11

pub_type

杂志文章
  • Contrast discrimination: a model and a hypothesis concerning the role of cholinergic modulation in contrast perception.

    abstract::A model of contrast discrimination performance in human observers is developed and then extended to cover effects on performance of anticholinergic drugs. It is shown that it is necessary to assume that neural noise increases at high spatial frequencies in order to provide a satisfactory model of variations in discrim...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800009123

    authors: Smith AT

    更新日期:1996-09-01 00:00:00

  • Pattern-reversal electroretinogram in response to chromatic stimuli: I. Humans.

    abstract::We have studied the steady-state PERG in human subjects in response to red-green plaid patterns modulated either in luminance or in chromaticity or both. By varying the relative luminance of the red and green components, a value could be obtained at which the PERG amplitude was either minimum or locally maximum. This ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800003825

    authors: Morrone C,Porciatti V,Fiorentini A,Burr DC

    更新日期:1994-09-01 00:00:00

  • The retinoids of seven species of mantis shrimp.

    abstract::Eyes of stomatopod crustaceans, or mantis shrimps, contain the greatest diversity of visual pigments yet described in any species, with as many as ten or more spectral classes present in a single retina. In this study, the eyes of seven species of mantis shrimp from three superfamilies of stomatopods were examined for...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s095252380000612x

    authors: Goldsmith TH,Cronin TW

    更新日期:1993-09-01 00:00:00

  • The interstitial nucleus of the superior fasciculus, posterior bundle (INSFp) in the guinea pig: another nucleus of the accessory optic system processing the vertical retinal slip signal.

    abstract::As in rabbit, gerbil, and rat, the guinea pig interstitial nucleus of the superior fasciculus, posterior bundle (INSFp) is a sparse assemblage of neurons scattered among the fibers forming the fasciculus bearing this name. Most of the INSFp neurons are small and are ovoid in shape. Interspersed among these, are a few ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800002182

    authors: Benassi C,Biral GP,Lui F,Porro CA,Corazza R

    更新日期:1989-01-01 00:00:00

  • Relating cone signals to color appearance: failure of monotonicity in yellow/blue.

    abstract::Observers performed red-green and yellow-blue hue cancellation tasks for a 0.8-deg circular test field on a dark surround, by manipulating the excitation level of one cone class while the other two classes were held constant. The results of the red-green judgments conformed to classical opponent color theory in that b...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523801186062

    authors: Knoblauch K,Shevell SK

    更新日期:2001-11-01 00:00:00

  • Depletion of retinal dopamine does not affect the ERG b-wave increment threshold function in goldfish in vivo.

    abstract::Increment threshold functions of the electroretinogram (ERG) b-wave were obtained from goldfish using an in vivo preparation to study intraretinal mechanisms underlying the increase in perceived brightness induced by depletion of retinal dopamine by 6-hydroxydopamine (6-OHDA). Goldfish received unilateral intraocular ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s095252380000300x

    authors: Lin ZS,Yazulla S

    更新日期:1994-07-01 00:00:00

  • Localization of AMPA-selective glutamate receptor subunits in the adult cat visual cortex.

    abstract::We have studied the presence and distribution of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA)-selective glutamate receptor subunits (GluR1, 2, 3, and 4) in the adult cat visual cortical areas 17, 18, 19, and the lateral suprasylvian areas (LSA). Reverse transcription-polymerase chain reaction (RT-PCR) a...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800007136

    authors: Gutiérrez-Igarza K,Fogarty DJ,Pérez-Cerdá F,Doñate-Oliver F,Albus K,Matute C

    更新日期:1996-01-01 00:00:00

  • The discoloration illusion.

    abstract::The discoloration illusion, a new visual phenomenon, is described. This phenomenon originates from the juxtaposition of eight chromatic parallel contours on a white background, creating a luminance gradient and enclosing a light red region. Under these conditions, the inner region appears white: the light red discolor...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523806233406

    authors: Pinna B

    更新日期:2006-05-01 00:00:00

  • Dark rearing reveals the mechanism underlying stimulus size tuning of superior colliculus neurons.

    abstract::Neurons in the superficial layers of the midbrain superior colliculus (SC) exhibit distinct tuning properties for visual stimuli, but, unlike neurons in the geniculocortical visual pathway, most respond best to visual stimuli that are smaller than the classical receptive field (RF). The mechanism underlying this size ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523806230062

    authors: Razak KA,Pallas SL

    更新日期:2006-09-01 00:00:00

  • Reaction time measures of adaptation to chromatic contrast.

    abstract::Simple reaction times (RTs) were measured to brief temporally blurred (total onset 570 ms) Gaussian isoluminant chromatic patches (s.d. 0.5 degrees) whose chromaticities lay along the cardinal chromatic axes (0 degrees, 90 degrees, 180 degrees, and 270 degrees in MBDKL color space). Bipolar adapting stimuli were emplo...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080449

    authors: Parry NR,Murray IJ,McKeefry DJ

    更新日期:2008-05-01 00:00:00

  • The functional organization of area V2, I: specialization across stripes and layers.

    abstract::We used qualitative tests to assess the sensitivity of 1043 V2 neurons (predominantly multiunits) in anesthetised macaque monkeys to direction, length, orientation, and color of moving bar stimuli. Spectral sensitivity was additionally tested by noting ON or OFF responses to flashed stimuli of varied size and color. T...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523802191164

    authors: Shipp S,Zeki S

    更新日期:2002-03-01 00:00:00

  • Effect of retinal impulse blockage on cytochrome oxidase-rich zones in the macaque striate cortex: II. Quantitative electron-microscopic (EM) analysis of neuropil.

    abstract::Unilateral retinal impulse blockage with tetrodotoxin (TTX) induces reversible shrinkage and decreased cytochrome oxidase (CO) activity in alternate rows of supragranular, CO-rich puffs in the adult macaque striate cortex (Wong-Riley & Carroll, 1984b: Carroll & Wong-Riley, 1987). The present study extended the finding...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800012396

    authors: Wong-Riley MT,Trusk TC,Tripathi SC,Hoppe DA

    更新日期:1989-01-01 00:00:00

  • Neural interactions between cone photoreceptors and horizontal cells in the turtle (Mauremys caspica) retina.

    abstract::Horizontal cells and cone photoreceptors in the vertebrate retina are interconnected by a complex network of synapses leading to the generation of color-coded responses in chromaticity horizontal cells. A simple cascade model of excitatory feedforward and inhibitory feedback synapses had been suggested to underlie the...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523898146047

    authors: Asi H,Perlman I

    更新日期:1998-01-01 00:00:00

  • Lagged cells in alert monkey lateral geniculate nucleus.

    abstract::Five lagged cells were recognized by extracellular recording in the lateral geniculate nucleus of an awake, behaving macaque monkey. Previous reports of lagged cells were all in the anesthetized cat. Both parvocellular and magnocellular lagged cells were observed. Response timing was distributed continuously across th...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080784

    authors: Saul AB

    更新日期:2008-09-01 00:00:00

  • Cholera toxin mapping of retinal projections in pigeons (Columbia livia), with emphasis on retinohypothalamic connections.

    abstract::Anterograde transport of cholera toxin subunit B (CTb) was used to study the retinal projections in birds, with an emphasis on retinohypothalamic connections. Pigeons (Columbia livia) were deeply anesthetized and received unilateral intraocular injections of CTb. In addition to known contralateral retinorecipient regi...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800002376

    authors: Shimizu T,Cox K,Karten HJ,Britto LR

    更新日期:1994-05-01 00:00:00

  • Rescue of excitation by inositol following Li(+)-induced block in Limulus ventral photoreceptors.

    abstract::The phosphoinositide (PI) intracellular signaling pathway, which triggers Ca2+ release from intracellular stores, appears to be a central feature of phototransduction in most invertebrate species studied. Procedures designed to inhibit PI-pathway reactions cause suppression of excitation to dim lights. However, in Lim...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523898151076

    authors: Johnson EC,Gray-Keller MP,O'Day PM

    更新日期:1998-01-01 00:00:00

  • Number and topography of cones, rods and optic nerve axons in New and Old World primates.

    abstract::To better understand the evolution of spatial and color vision, the number and spatial distributions of cones, rods, and optic nerve axon numbers were assessed in seven New World primates (Cebus apella, Saimiri ustius, Saguinus midas niger, Alouatta caraya, Aotus azarae, Calllithrix jacchus, and Callicebus moloch). Th...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080371

    authors: Finlay BL,Franco EC,Yamada ES,Crowley JC,Parsons M,Muniz JA,Silveira LC

    更新日期:2008-05-01 00:00:00

  • Effects of different forms of monocular deprivation on primary visual cortex maps.

    abstract::Monocular deprivation (MD) by lid suture is one of the classic paradigms for the study of developmental plasticity in the cerebral cortex, and we have detailed knowledge of its anatomical and physiological consequences as well as underlying molecular and cellular mechanisms. However, the effects of other forms of mani...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523812000260

    authors: Jaffer S,Vorobyov V,Sengpiel F

    更新日期:2012-09-01 00:00:00

  • Morphology and visual pigment content of photoreceptors from injured goldfish retina.

    abstract::Adult teleost fish retinas can regenerate neurons following either surgical or pharmacological injury. The cellular milieu of the damaged retina within which regenerated neurons are produced might be different in these two model systems of retinal injury, and thus the phenotypic attributes of regenerated neurons in th...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800174115

    authors: Cameron DA,Powers MK

    更新日期:2000-07-01 00:00:00

  • Characteristics of period doubling in the human cone flicker electroretinogram.

    abstract::Electroretinogram (ERG) responses of the cone system to a flickering stimulus can exhibit a cyclic variation in amplitude. This phenomenon of synchronous period doubling has been attributed to a nonlinear feedback mechanism within the retina that alters response gain. The aim of the present study was to investigate in...

    journal_title:Visual neuroscience

    pub_type: 临床试验,杂志文章

    doi:10.1017/S0952523805226111

    authors: Alexander KR,Levine MW,Super BJ

    更新日期:2005-11-01 00:00:00

  • Cone synapses in macaque fovea: I. Two types of non-S cones are distinguished by numbers of contacts with OFF midget bipolar cells.

    abstract::L and M cones, divided into two groups by absorption spectra, have not been distinguished by structure. Here, we report what may be such a difference. We reconstructed the synaptic terminals of 16 non-S cones and the dendritic arbors of their ON and OFF midget bipolar cells from high-magnification electron micrographs...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523810000477

    authors: Schein S,Ngo IT,Huang TM,Klug K,Sterling P,Herr S

    更新日期:2011-01-01 00:00:00

  • Virtual evolution for visual search in natural images results in behavioral receptive fields with inhibitory surrounds.

    abstract::The neural mechanisms driving perception and saccades during search use information about the target but are also based on an inhibitory surround not present in the target luminance profile (e.g., Eckstein et al., 2007). Here, we ask whether these inhibitory surrounds might reflect a strategy that the brain has adapte...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523809090014

    authors: Zhang S,Abbey CK,Eckstein MP

    更新日期:2009-01-01 00:00:00

  • The relationship between GABA-containing cells and the cholinergic circuitry in the rabbit retina.

    abstract::As a part of ongoing efforts to understand the cholinergic circuitry in the mammalian retina, we studied the coexpression of nicotinic acetylcholine receptors (nAChRs) and gamma-aminobutyric acid (GABA), the GABA transporter 1 (GAT-1), or choline acetyltransferase (ChAT) immunoreactivity in the rabbit retina. Double-l...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523801181083

    authors: Dmitrieva NA,Lindstrom JM,Keyser KT

    更新日期:2001-01-01 00:00:00

  • Synaptic inputs to retrogradely labeled ganglion cells in the retina of the cane toad, Bufo marinus.

    abstract::The entire population of ganglion cells in the retina of the toad Bufo marinus was labeled by retrograde transport of a lysine-fixable biotinylated dextran amine of 3000 molecular weight. Synaptic connections between bipolar, amacrine, and ganglion cells in the inner plexiform layer were quantitatively analyzed, with ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800011792

    authors: Zhu BS,Gibbins IL

    更新日期:1997-11-01 00:00:00

  • Morphology of retinogeniculate axons in the macaque.

    abstract::The size, pattern of terminal arborizations, and laminar specificity of individual retinogeniculate axons were studied in the macaque following injections of HRP into the optic tract. Axons that terminated in the magnocellular layers had significantly larger fiber diameters and wider terminal fields than those that te...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800001206

    authors: Conley M,Fitzpatrick D

    更新日期:1989-01-01 00:00:00

  • Size-difference thresholds after lesions of thalamic visual nuclei in pigeons.

    abstract::Nucleus rotundus and nucleus dorsolateralis posterior (DLP) are the thalamic components of two parallel pathways within the tectofugal division of the pigeon visual system. An earlier study (Hodos, Weiss & Bessette, 1986) had shown that lesions in direct telencephalic recipients of projections from rotundus and DLP pr...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800001036

    authors: Kertzman C,Hodos W

    更新日期:1988-01-01 00:00:00

  • Regenerating axons from adult chick retinal ganglion cells recognize topographic cues from embryonic central targets.

    abstract::We investigated whether regenerating mature axons recapitulate embryonic features essential to successful reconnectivity within the injured nervous system. Strips from embryonic and adult chick retinae were cultured, and outgrowing axons were examined morphometrically and immunohistochemically. In addition, the target...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800002558

    authors: Vanselow J,Müller B,Thanos S

    更新日期:1991-06-01 00:00:00

  • Center/surround organization of retinal bipolar cells: High correlation of fundamental responses of center and surround to sinusoidal contrasts.

    abstract::Receptive field organization of cone-driven bipolar cells was investigated by intracellular recording in the intact light-adapted retina of the tiger salamander (Ambystoma tigrinum). Centered spots and concentric annuli of optimum dimensions were used to selectively stimulate the receptive field center and surround wi...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523811000071

    authors: Burkhardt DA,Bartoletti TM,Thoreson WB

    更新日期:2011-05-01 00:00:00

  • Distribution of the alpha1 subunit of the GABA(A) receptor on midget and parasol ganglion cells in the retina of the common marmoset Callithrix jacchus.

    abstract::The inhibitory neurotransmitter gamma aminobutyric acid (GABA) has been shown to influence the responses of ganglion cells in the mammalian retina. Consistently, GABA(A) receptor subunits have been localized to different ganglion cell types. In this study, the distribution of the alpha1 subunit of the GABA(A) receptor...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800173109

    authors: Macri J,Martin PR,Grünert U

    更新日期:2000-05-01 00:00:00

  • The determination of total cGMP levels in rod outer segments from intact toad photoreceptors in response to light superimposed on background and to consecutive flashes: a second light flash accelerates the dark recovery rate of cGMP levels in control medi

    abstract::In previous experiments we established that a light flash reduced cGMP levels of toad rod outer segments within the transduction time interval, but that recovery of the dark level of cGMP occurred more slowly than reported electrophysiological recovery of membrane potential. We now report that a second light flash acc...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800003230

    authors: Cohen AI,Blazynski C

    更新日期:1993-01-01 00:00:00