Abstract:
:L and M cones, divided into two groups by absorption spectra, have not been distinguished by structure. Here, we report what may be such a difference. We reconstructed the synaptic terminals of 16 non-S cones and the dendritic arbors of their ON and OFF midget bipolar cells from high-magnification electron micrographs of serial thin sections of a small region of macaque fovea. Each cone terminal contacted a similar number (~16) of invaginating central elements provided by its ON midget bipolar cell. By contrast, the numbers of connections between a cone terminal and its OFF midget bipolar cell were grouped into two clusters: 30-37 versus 43-50 basal contacts in the triad-associated position and 41-47 versus 61-74 Outer Densities within those basal contacts. The coefficients of variation of these distributions were all in the range of 10% or lower, characteristic of single populations. If these two clusters correspond to M- and L-cone circuits, the results reveal structural differences between M and L cones and between their corresponding OFF midget bipolar cells.
journal_name
Vis Neuroscijournal_title
Visual neuroscienceauthors
Schein S,Ngo IT,Huang TM,Klug K,Sterling P,Herr Sdoi
10.1017/S0952523810000477subject
Has Abstractpub_date
2011-01-01 00:00:00pages
3-16issue
1eissn
0952-5238issn
1469-8714pii
S0952523810000477journal_volume
28pub_type
杂志文章abstract::The inhibition of [3H]acetylcholine (ACh) release from cholinergic amacrine cells by glycine and GABA was studied using an in vivo eyecup preparation in anesthetized rabbits. Glycine (1 mM) had no effect on basal ACh release, but completely blocked the light-evoked release of ACh. Glycine also blocked the strong poten...
journal_title:Visual neuroscience
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pub_type: 杂志文章,评审
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journal_title:Visual neuroscience
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doi:10.1017/S0952523812000260
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journal_title:Visual neuroscience
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800012499
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pub_type: 杂志文章
doi:10.1017/S0952523814000066
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pub_type: 杂志文章
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