Abstract:
:Intrinsic interneurons within the dorsal lateral geniculate nucleus (dLGN) provide a feed-forward inhibitory pathway for afferent visual information originating from the retina. These interneurons are unique because in addition to traditional axodendritic output onto thalamocortical neurons, these interneurons have presynaptic dendrites that form dendrodendritic synapses onto thalamocortical neurons as well. These presynaptic dendrites, termed F2 terminals, are tightly coupled to the retinogeniculate afferents that synapse onto thalamocortical relay neurons. Retinogeniculate stimulation of F2 terminals can occur through the activation of ionotropic and/or metabotropic glutamate receptors. The stimulation of ionotropic glutamate receptors can occur with single stimuli and produces a short-lasting inhibition of the thalamocortical neuron. By contrast, activation of metabotropic glutamate receptors requires tetanic activation and results in longer-lasting inhibition in the thalamocortical neuron. The F2 terminals are predominantly localized to the distal dendrites of interneurons, and the excitation and output of F2 terminals can occur independent of somatic activity within the interneuron thereby allowing these F2 terminals to serve as independent processors, giving rise to focal inhibition. By contrast, strong transient depolarizations at the soma can initiate a backpropagating calcium-mediated potential that invades the dendritic arbor activating F2 terminals and leading to a global form of inhibition. These distinct types of output, focal versus global, could play an important role in the temporal and spatial roles of inhibition that in turn impacts thalamocortical information processing.
journal_name
Vis Neuroscijournal_title
Visual neuroscienceauthors
Cox CL,Beatty JAdoi
10.1017/S0952523817000141subject
Has Abstractpub_date
2017-01-01 00:00:00pages
E017eissn
0952-5238issn
1469-8714pii
S0952523817000141journal_volume
34pub_type
杂志文章,评审abstract::Receptive field organization of cone-driven bipolar cells was investigated by intracellular recording in the intact light-adapted retina of the tiger salamander (Ambystoma tigrinum). Centered spots and concentric annuli of optimum dimensions were used to selectively stimulate the receptive field center and surround wi...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523811000071
更新日期:2011-05-01 00:00:00
abstract::The goal of this work was to provide a detailed quantitative description of the receptive-field properties of one of the types of rarely encountered retinal ganglion cells of cat; the cell named the Q-cell by Enroth-Cugell et al. (1983). Quantitative comparisons are made between the discharge statistics and between th...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800007975
更新日期:1995-03-01 00:00:00
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journal_title:Visual neuroscience
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doi:10.1017/S095252380623325X
更新日期:2006-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523804216054
更新日期:2004-11-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800011652
更新日期:1997-09-01 00:00:00
abstract::Extrastriate areas TEO and V4 have been associated with form and color vision. Area V4 has also been suggested to participate in processes concerned with attention, stimulus salience, and perceptual learning. In a continuing effort to elucidate the connectional interactions and microcircuitry of these areas, we descri...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800002480
更新日期:1994-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800001334
更新日期:1991-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523806231055
更新日期:2006-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800006398
更新日期:1992-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800005496
更新日期:1989-10-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252380118404x
更新日期:2001-07-01 00:00:00
abstract::We have studied the steady-state PERG in human subjects in response to red-green plaid patterns modulated either in luminance or in chromaticity or both. By varying the relative luminance of the red and green components, a value could be obtained at which the PERG amplitude was either minimum or locally maximum. This ...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800003825
更新日期:1994-09-01 00:00:00
abstract::To examine the role of visual area V4 in pattern vision, we tested two monkeys with lesions of V4 on tasks that required them to discriminate the orientation of contours defined by several different cues. The cues used to separate the contours from their background included luminance, color, motion, and texture, as we...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800008208
更新日期:1996-05-01 00:00:00
abstract::This study has shown that the retinae of Prototherian (egg-laying) mammals possess two neuronal types that are present in non-mammalian retinae, but absent or morphologically different in the retinae of Eutherian (placental) mammals. First, endogenous serotonin-like immunoreactivity has been localized in a population ...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800000079
更新日期:1990-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800010920
更新日期:1991-07-01 00:00:00
abstract::Ablation of visual cortical areas 17 and 18 in neonatal and young adult cats induces novel retinal projections to terminate bilaterally in the lateral posterior nucleus (LP) at a position ventromedial from the medial interlaminar nucleus. Comparison with the visual-field maps of LP indicate that the terminations are f...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800005435
更新日期:1993-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523812000235
更新日期:2012-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800002893
更新日期:1992-03-01 00:00:00
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journal_title:Visual neuroscience
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doi:10.1017/S0952523809090105
更新日期:2009-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
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更新日期:1998-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800003102
更新日期:1994-07-01 00:00:00
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更新日期:2000-03-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800003230
更新日期:1993-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252389815304x
更新日期:1998-05-01 00:00:00
abstract::Although the neural location of the plaid motion coherence process is not precisely known, the middle temporal (MT) cortical area has been proposed as a likely candidate. This claim rests largely on the neurophysiological findings showing that in response to plaid stimuli, a subgroup of cells in area MT responds to th...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252380000852x
更新日期:1996-07-01 00:00:00
abstract::Parallel processing of visual information begins at the first synapse in the retina between the photoreceptors and bipolar cells. Ten bipolar cell types have been previously described in the primate retina: one rod and nine cone bipolar types. In this paper, we describe an 11th type of bipolar cell identified in Golgi...
journal_title:Visual neuroscience
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更新日期:2011-01-01 00:00:00
abstract::The retinae of insectivores have been rarely studied, and their photoreceptor arrangements and expression patterns of visual pigments are largely unknown. We have determined the presence and distribution of cones in three species of shrews (common shrew Sorex araneus, greater white-toothed shrew Crocidura russula, dar...
journal_title:Visual neuroscience
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journal_title:Visual neuroscience
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journal_title:Visual neuroscience
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journal_title:Visual neuroscience
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doi:10.1017/s0952523800171093
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