Comparison of the responses to light and to GABA of cells postsynaptic to barnacle photoreceptors (I-cells).

Abstract:

:We tested the hypothesis that gamma-aminobutyric acid (GABA) is the transmitter released by barnacle photoreceptors onto postsynaptic cells (I-cells). GABA was applied to I-cells either by superfusion or by ejecting it with pressure from a pipette positioned close to the I-cell's soma. The I-cell's response to GABA was compared with its response to light (i.e. to the photoreceptors' transmitter) by recording intracellularly from its soma. Bath-applied (100 microns to 10 mM) and pressure-applied GABA (10 mM in pipette) hyperpolarizes I-cells by increasing their conductance, as does the photoreceptors' transmitter. The response to pressure-applied GABA consists of two components; both persist when Co2+ or Cd2+ are added to the saline to block synaptic transmission in the preparation, indicating that GABA affects the I-cell directly rather than affecting a presynaptic cell. GABA hyperpolarizes the I-cell when applied to the cell over the soma and ipsilateral arbor or over the contralateral arbor. The I-cells' responses to GABA and to light both depend on extracellular K+ and are affected by changes in intracellular and extracellular Cl-. However, picrotoxin and beta-guanidinopropionic acid block the response to pressure-applied GABA but do not block the response to light even at an order of magnitude higher concentration. Thus, GABA is not likely to be the transmitter that causes the hyperpolarizing response of the I-cell. It may be a neuromodulator or the transmitter of an unknown input to the I-cell.

journal_name

Vis Neurosci

journal_title

Visual neuroscience

authors

Callaway JC,Stuart AE

doi

10.1017/s0952523800005496

subject

Has Abstract

pub_date

1989-10-01 00:00:00

pages

301-10

issue

4

eissn

0952-5238

issn

1469-8714

pii

S0952523800005496

journal_volume

3

pub_type

杂志文章
  • Linking perception to neural activity as measured by visual evoked potentials.

    abstract::Linking propositions have played an important role in refining our understanding of the relationship between neural activity and perception. Over the last 40 years, visual evoked potentials (VEPs) have been used in many different ways to address questions of the relationship between neural activity and perception. Thi...

    journal_title:Visual neuroscience

    pub_type: 杂志文章,评审

    doi:10.1017/S0952523813000205

    authors: Norcia AM

    更新日期:2013-11-01 00:00:00

  • Characteristics of period doubling in the human cone flicker electroretinogram.

    abstract::Electroretinogram (ERG) responses of the cone system to a flickering stimulus can exhibit a cyclic variation in amplitude. This phenomenon of synchronous period doubling has been attributed to a nonlinear feedback mechanism within the retina that alters response gain. The aim of the present study was to investigate in...

    journal_title:Visual neuroscience

    pub_type: 临床试验,杂志文章

    doi:10.1017/S0952523805226111

    authors: Alexander KR,Levine MW,Super BJ

    更新日期:2005-11-01 00:00:00

  • Long-range interactions modulate the contrast gain in the lateral geniculate nucleus of cats.

    abstract::In previous work, we have shown that sudden image displacements well outside the classical receptive field modulate the visual sensitivity of LGN relay cells. Here we report the effect of image displacements on the response versus contrast function. The stimuli consisted of a central spot of optimal size and polarity ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523899165143

    authors: Felisberti F,Derrington AM

    更新日期:1999-09-01 00:00:00

  • Visual experience promotes the isotropic representation of orientation preference.

    abstract::Within the visual cortex of several mammalian species, more circuitry is devoted to the representation of vertical and horizontal orientations than oblique orientations. The sensitivity of this representation of orientation preference to visual experience during cortical maturation and the overabundance of cardinal co...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523804041045

    authors: Coppola DM,White LE

    更新日期:2004-01-01 00:00:00

  • Galvanic vestibular stimulation modulates the electrophysiological response during face processing.

    abstract::Although galvanic vestibular stimulation (GVS) is known to affect the speed and accuracy of visual judgments, the underlying electrophysiological response has not been explored. In the present study, we therefore investigated the effect of GVS on the N170 event-related potential, a marker commonly associated with earl...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523812000235

    authors: Wilkinson D,Ferguson HJ,Worley A

    更新日期:2012-09-01 00:00:00

  • Whole-cell recording of light-evoked photoreceptor responses in a slice preparation of the cuttlefish retina.

    abstract::A new tissue slice preparation of the cuttlefish eye is described that permits patch-clamp recordings to be acquired from intact photoreceptors during stimulation of the retina with controlled light flashes. Whole-cell recordings using this preparation, from the retinas of very young Sepia officinalis demonstrated tha...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523805223106

    authors: Chrachri A,Nelson L,Williamson R

    更新日期:2005-05-01 00:00:00

  • Visual latency and brightness: an interpretation based on the responses of rods and ganglion cells in the frog retina.

    abstract::Rod and cone photoresponses in a variety of species have been accurately described with linear multistage filter models. In this study, the response latency and initial coding of intensity at two higher levels of visual processing are related to such photoreceptor responses. One level is the retinal output (spiking di...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800012499

    authors: Donner K

    更新日期:1989-07-01 00:00:00

  • Inhibitory components of retinal bipolar cell receptive fields are differentially modulated by dopamine D1 receptors.

    abstract::During adaptation to an increase in environmental luminance, retinal signaling adjustments are mediated by the neuromodulator dopamine. Retinal dopamine is released with light and can affect center-surround receptive fields, the coupling state between neurons, and inhibitory pathways through inhibitory receptors and n...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523819000129

    authors: Mazade RE,Eggers ED

    更新日期:2020-02-12 00:00:00

  • Large retinal ganglion cells in the pipid frog Xenopus laevis form independent, regular mosaics resembling those of teleost fishes.

    abstract::Population-based studies of retinal neurons have helped to reveal their natural types in mammals and teleost fishes. In this, the first such study in a frog, labeled ganglion cells of the mesobatrachian Xenopus laevis were examined in flatmounts. Cells with large somata and thick dendrites could be divided into three ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s095252380001155x

    authors: Shamim KM,Tóth P,Cook JE

    更新日期:1997-09-01 00:00:00

  • Reduction of ocular blood flow results in glial fibrillary acidic protein (GFAP) expression in rat retinal Müller cells.

    abstract::Reduction of blood flow to the rat retina was achieved by either clamping both carotid arteries briefly (24 min) or combining clamping of the carotid arteries with permanent occlusion of the vertebral arteries. Analysis of retinas 6 days after operations showed that GFAP immunoreactivity is expressed throughout the re...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800010427

    authors: Osborne NN,Block F,Sontag KH

    更新日期:1991-12-01 00:00:00

  • Bipolar or rectified chromatic detection mechanisms?

    abstract::It is widely accepted that human color vision is based on two types of cone-opponent mechanism, one differencing L and M cone types (loosely termed "red-green"), and the other differencing S with the L and M cones (loosely termed "blue-yellow"). The traditional view of the early processing of human color vision sugges...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523801181125

    authors: Sankeralli MJ,Mullen KT

    更新日期:2001-01-01 00:00:00

  • Movement of retinal along cone and rod photoreceptors.

    abstract::Single isolated photoreceptors can be taken through a visual cycle of light adaptation by bleaching visual pigment, followed by dark adaptation when supplied with 11-cis retinal. Light adaptation after bleaching is manifested by faster response kinetics and a permanent reduction in sensitivity to light flashes, presum...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800001735

    authors: Jin J,Jones GJ,Cornwall MC

    更新日期:1994-03-01 00:00:00

  • Early development of eye and retina in lanternfish larvae.

    abstract::The morphological characteristics of the eyes and the retinae of lanternfish larvae of Lampanyctus crocodilus, Benthosema glaciale, and Myctophum punctatum were analyzed in pre-flexion, flexion, and post-flexion stages. Pre-flexion larvae of L. crocodilus, the species with the shallowest depth distribution, had spheri...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523807070484

    authors: Bozzano A,Pankhurst PM,Sabatés A

    更新日期:2007-05-01 00:00:00

  • Spatio-temporal characterization of retinal opsin gene expression during thyroid hormone-induced and natural development of rainbow trout.

    abstract::The abundance and spatial distribution of retinal cone photoreceptors change during thyroid hormone (TH)-induced and natural development of rainbow trout (Oncorhynchus mykiss). These changes are thought to allow the fish to adapt to different photic environments throughout its life history. To date, the ontogeny of ra...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523806232139

    authors: Veldhoen K,Allison WT,Veldhoen N,Anholt BR,Helbing CC,Hawryshyn CW

    更新日期:2006-03-01 00:00:00

  • Contrast discrimination: a model and a hypothesis concerning the role of cholinergic modulation in contrast perception.

    abstract::A model of contrast discrimination performance in human observers is developed and then extended to cover effects on performance of anticholinergic drugs. It is shown that it is necessary to assume that neural noise increases at high spatial frequencies in order to provide a satisfactory model of variations in discrim...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800009123

    authors: Smith AT

    更新日期:1996-09-01 00:00:00

  • Topographic analysis of the ganglion cell layer in the retina of the four-eyed fish Anableps anableps.

    abstract::Fish of the genus Anableps (Anablepidae, Cyprinodontiformes) have eyes that are adapted for simultaneous aerial and aquatic vision. In this study we investigate some of the corresponding retinal specializations of the adult Anableps anableps eye using retinal transverse sections and wholemounts. The linear dimensions ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523806230232

    authors: Oliveira FG,Coimbra JP,Yamada ES,Montag LF,Nascimento FL,Oliveira VA,da Mota DL,Bittencourt AM,da Silva VL,da Costa BL

    更新日期:2006-11-01 00:00:00

  • Differential induction of gene expression by basic fibroblast growth factor and neuroD in cultured retinal pigment epithelial cells.

    abstract::Embryonic chick retinal pigment epithelial (RPE) cells can undergo transdifferentiation upon appropriate stimulation. For example, basic fibroblast growth factor (bFGF) induces intact RPE tissue younger than embryonic day 4.5 (E4.5) to transdifferentiate into a neural retina. NeuroD, a gene encoding a basic helix-loop...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800171172

    authors: Yan RT,Wang SZ

    更新日期:2000-03-01 00:00:00

  • Contacts of dopaminergic interplexiform cells in the outer retina of the blue acara.

    abstract::Dopaminergic interplexiform cells in the retina of the blue acara were investigated using an antiserum against tyrosine hydroxylase and PAP visualization. In whole-mount preparations, we observed a homogeneous distribution of cell bodies throughout the retina without any indication of regional specialization. At the f...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800010737

    authors: Wagner HJ,Wulle I

    更新日期:1992-09-01 00:00:00

  • Background contrast modulates kinetics and lateral spread of responses to superimposed stimuli in outer retina.

    abstract::Surround enhancement (sensitization) is a poorly understood form of network adaptation in which the kinetics of the responses of retinal neurons to test stimuli become faster, and absolute sensitivity of the responses increases with increasing level of steady, surrounding light. Surround enhancement has been observed ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800006751

    authors: Reifsnider ES,Tranchina D

    更新日期:1995-11-01 00:00:00

  • Currents in the presynaptic terminal arbors of barnacle photoreceptors.

    abstract::We have described the currents flowing across the presynaptic membranes of the four median photoreceptors of the giant barnacle, Balanus nubilus, using a quasi-voltage clamp arrangement. Membrane potential, measured in the terminal region of one photoreceptor, was controlled in all four terminals by feedback current s...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800003667

    authors: Hayashi JH,Stuart AE

    更新日期:1993-03-01 00:00:00

  • Cone synapses in macaque fovea: I. Two types of non-S cones are distinguished by numbers of contacts with OFF midget bipolar cells.

    abstract::L and M cones, divided into two groups by absorption spectra, have not been distinguished by structure. Here, we report what may be such a difference. We reconstructed the synaptic terminals of 16 non-S cones and the dendritic arbors of their ON and OFF midget bipolar cells from high-magnification electron micrographs...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523810000477

    authors: Schein S,Ngo IT,Huang TM,Klug K,Sterling P,Herr S

    更新日期:2011-01-01 00:00:00

  • Calcium-permeable glutamate receptors in horizontal cells of the mammalian retina.

    abstract::Mechanisms that mediate the calcium influx in mammalian horizontal cells were studied. Horizontal cells (HCs) enzymatically dissociated from the rabbit retina were recorded by the whole-cell configuration of the patch-clamp technique and by calcium image ratioespectrophotometry of Fura-2 loaded cells. AMPA-preferring ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:

    authors: Rivera L,Blanco R,de la Villa P

    更新日期:2001-11-01 00:00:00

  • Number and topography of cones, rods and optic nerve axons in New and Old World primates.

    abstract::To better understand the evolution of spatial and color vision, the number and spatial distributions of cones, rods, and optic nerve axon numbers were assessed in seven New World primates (Cebus apella, Saimiri ustius, Saguinus midas niger, Alouatta caraya, Aotus azarae, Calllithrix jacchus, and Callicebus moloch). Th...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080371

    authors: Finlay BL,Franco EC,Yamada ES,Crowley JC,Parsons M,Muniz JA,Silveira LC

    更新日期:2008-05-01 00:00:00

  • Selective labeling of visual corpus callosum connections with aspartate in cat and rat.

    abstract::Tritiated neurotransmitter candidates were unilaterally injected in visual cortical regions with abundant corpus callosum connections. D-aspartate (Asp) or gamma-aminobutyric acid (GABA) was injected along the area 17/18 border in cat, and the area 17/18a and 17/18b borders in rat. Retrograde Asp label was found contr...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800004351

    authors: Elberger AJ

    更新日期:1989-01-01 00:00:00

  • Intact "biological motion" and "structure from motion" perception in a patient with impaired motion mechanisms: a case study.

    abstract::A series of psychophysical tests examining early and later aspects of image-motion processing were conducted in a patient with bilateral lesions involving the posterior visual pathways, affecting the lateral parietal-temporal-occipital cortex and the underlying white matter (as shown by magnetic resonance imaging stud...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800000444

    authors: Vaina LM,Lemay M,Bienfang DC,Choi AY,Nakayama K

    更新日期:1990-10-01 00:00:00

  • Effect of temporal sparseness and dichoptic presentation on multifocal visual evoked potentials.

    abstract::Multifocal VEP (mfVEP) responses were obtained from 13 normal human subjects for nine test conditions, covering three viewing conditions (dichoptic and left and right monocular), and three different temporal stimulation forms (rapid contrast reversal, rapid pattern pulse presentation, and slow pattern pulse presentati...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523805221053

    authors: James AC,Ruseckaite R,Maddess T

    更新日期:2005-01-01 00:00:00

  • Synaptic inputs to retrogradely labeled ganglion cells in the retina of the cane toad, Bufo marinus.

    abstract::The entire population of ganglion cells in the retina of the toad Bufo marinus was labeled by retrograde transport of a lysine-fixable biotinylated dextran amine of 3000 molecular weight. Synaptic connections between bipolar, amacrine, and ganglion cells in the inner plexiform layer were quantitatively analyzed, with ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800011792

    authors: Zhu BS,Gibbins IL

    更新日期:1997-11-01 00:00:00

  • Cell density ratios in a foveal patch in macaque retina.

    abstract::We examine the assumptions that the fovea contains equal numbers of inner (invaginating or ON) and outer (flat or OFF) midget bipolar cells and equal numbers of inner and outer diffuse bipolar cells. Based on reconstruction from electron photomicrographs of serial thin sections through the fovea of a macaque monkey, w...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523803202091

    authors: Ahmad KM,Klug K,Herr S,Sterling P,Schein S

    更新日期:2003-03-01 00:00:00

  • Optimal design of photoreceptor mosaics: why we do not see color at night.

    abstract::While color vision mediated by rod photoreceptors in dim light is possible (Kelber & Roth, 2006), most animals, including humans, do not see in color at night. This is because their retinas contain only a single class of rod photoreceptors. Many of these same animals have daylight color vision, mediated by multiple cl...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S095252380808084X

    authors: Manning JR,Brainard DH

    更新日期:2009-01-01 00:00:00

  • A comparison of the components of the multifocal and full-field ERGs.

    abstract::The multi-input technique of Sutter and Tran (1992) yields multiple focal ERGs. The purpose here was to compare the components of this multifocal ERG to the components of the standard, full-field ERG. To record multifocal ERGs, an array of 103 hexagons was displayed on a monitor. Full-field (Ganzfeld) ERGs were elicit...

    journal_title:Visual neuroscience

    pub_type: 临床试验,杂志文章

    doi:10.1017/s0952523800012190

    authors: Hood DC,Seiple W,Holopigian K,Greenstein V

    更新日期:1997-05-01 00:00:00