Number and topography of cones, rods and optic nerve axons in New and Old World primates.

Abstract:

:To better understand the evolution of spatial and color vision, the number and spatial distributions of cones, rods, and optic nerve axon numbers were assessed in seven New World primates (Cebus apella, Saimiri ustius, Saguinus midas niger, Alouatta caraya, Aotus azarae, Calllithrix jacchus, and Callicebus moloch). The spatial distribution and number of rods and cones was determined from counts of retinal whole mounts. Optic axon number was determined from optic nerve sections by electron microscopy. These data were amassed with existing data on retinal cell number and distribution in Old World primates, and the scaling of relative densities and numbers with respect to retinal area, eye and brain sizes, and foveal specializations were evaluated. Regular scaling of all cell types was observed, with the exceptionally large, rod-enriched retina of the nocturnal owl monkey Aotus azarae, and the unusually high cone density of the fovea of the trichromatic howler monkey Alouatta caraya presenting interesting variations on this basic plan. Over all species, the lawful scaling of rods, cones, and retinal ganglion cell number is hypothesized to result from a conserved sequence of cell generation that defends retinal acuity and sensitivity over a large range of eye sizes.

journal_name

Vis Neurosci

journal_title

Visual neuroscience

authors

Finlay BL,Franco EC,Yamada ES,Crowley JC,Parsons M,Muniz JA,Silveira LC

doi

10.1017/S0952523808080371

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

289-99

issue

3

eissn

0952-5238

issn

1469-8714

pii

S0952523808080371

journal_volume

25

pub_type

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