Factor XIIIa+ dendritic cells and S-100 protein+ Langerhans' cells in adult periodontitis.

abstract：:Accumulating evidence indicates that TNFalpha plays an important role in the pathogenesis of periodontitis, but the effect of TNFalpha on the degradation of the periodontal ligament is not well understood. This study used reverse transcriptase-PCR to investigate the effects of TNFalpha on matrix metalloproteinase (MMP...

journal_title：Journal of periodontal research

authors： Nishikawa M,Yamaguchi Y,Yoshitake K,Saeki Y

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Aggregatibacter actinomycetemcomitans is one of the etiological pathogens implicated in the onset of periodontal disease. This pathogen produces cytolethal distending toxin (CDT) that acts as a genotoxin to induce cell cycle arrest and cellular distension in cultured cell lines. Therefore, CDT is a possible ...

journal_title：Journal of periodontal research

authors： Ohara M,Miyauchi M,Tsuruda K,Takata T,Sugai M

更新日期：2011-06-01 00:00:00

abstract：:The immunoglobulin class distribution of antibody to human collagen type I has been examined in sera and gingival extracts from patients with adult chronic periodontitis. Tissue extracts were made either by simple washing or ultrasonication. With either method, IgG and IgA antibodies to collagen were present in higher...

journal_title：Journal of periodontal research

authors： Anusaksathien O,Singh G,Matthews N,Dolby AE

更新日期：1992-01-01 00:00:00

abstract：:Numerous studies report that water fluoridation reduces caries in children, but little current evidence exists about fluoridation's effects on the periodontal health of adults. To address this issue, we estimated fluoridation effects on periodontal disease among 1066 Washington state employees and their spouses, aged ...

journal_title：Journal of periodontal research

authors： Grembowski D,Fiset L,Spadafora A,Milgrom P

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Biological plausibility of an association between severe periodontitis and cardiovascular disease (CVD) has been proven. Genetic characteristics play an important role in both complex inflammatory diseases. Polymorphisms (single nucleotide polymorphisms [SNPs]) in the long noncoding RNA, antise...

journal_title：Journal of periodontal research

authors： Schulz S,Seitter L,Werdan K,Hofmann B,Schaller HG,Schlitt A,Reichert S

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Aggregatibacter actinomycetemcomitans is involved in oral and systemic infections, and is associated with, eg aggressive forms of periodontitis and with endocarditis. The cagE gene encodes a ≈39 kDa putative exotoxin expressed by A. actinomycetemcomitans. The level of conservation of cagE, and ...

journal_title：Journal of periodontal research

authors： Johansson A,Claesson R,Höglund Åberg C,Haubek D,Oscarsson J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Retinoic acid (RA) exerts a wide variety of effects on development, cellular differentiation and homeostasis in various tissues. However, little is known about the effects of RA on the differentiation of periodontal ligament cells. In this study, we investigated whether RA can affect the dexam...

journal_title：Journal of periodontal research

authors： Shibuya N,Nemoto E,Kanaya S,Kunii R,Shimauchi H

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Autoimmune diseases, including atherosclerosis, diabetes mellitus and rheumatoid arthritis, can be triggered and aggravated by the pathogen-driven antigenic peptide from Porphyromonas gingivalis HSP60. P. gingivalis is the major pathogen of chronic periodontitis, which is a global epidemic prev...

journal_title：Journal of periodontal research

authors： Jeong E,Lee JY,Kim SJ,Choi J

更新日期：2012-12-01 00:00:00

abstract：:This study investigated the cell surface expression of CD11b (Mo 1, Mac-1, CR 3) by neutrophils (PMNs) from human crevicular fluid (CF-PMNs). CD11b expression on CF-PMNs was compared, using flow cytometry, to that on peripheral blood PMNs (PB-PMNs) isolated simultaneously from the same subjects. CD11b expression by CF...

journal_title：Journal of periodontal research

authors： Watanabe K,Hagen KL,Andersen BR

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:This study investigated the oxidative burst function of peripheral phagocytic cells (granulocytes and monocytes) and assessed the relation between oxidative burst and periodontal status in adult individuals with Down syndrome (DS) vs. other groups. METHODS:Of 55 DS individuals (18-56 years old), 74 individu...

journal_title：Journal of periodontal research

authors： Khocht A,Russell B,Cannon JG,Turner B,Janal M

更新日期：2014-02-01 00:00:00

abstract：:Four rough-surfaced (R) and three smooth-surfaced (S) clinical isolates of Capnocytophaga obtained from the subgingival plaque of periodontitis patients were studied for their peptidase and protease profiles. The results were compared with those obtained with C. gingivalis (which has a smooth morphology). All cell ext...

journal_title：Journal of periodontal research

authors： Söderling E,Mäkinen PL,Syed S,Mäkinen KK

更新日期：1991-01-01 00:00:00

abstract：:The purpose of this study was to evaluate the biological effects of guided tissue regeneration (GTR) membrane materials, per se, on the periodontal tissue regeneration. Rat periodontal ligament (PDL)-derived cells were used to study the attachment, proliferation and differentiation, in vitro, on various GTR membranes....

journal_title：Journal of periodontal research

authors： Takata T,Wang HL,Miyauchi M

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate whether a peptide-based coating can prevent the adhesion of Porphyromonas gingivalis, a key human pathogen associated with periodontitis and peri-implantitis. BACKGROUND:Nonsurgical and surgical interventions have been used for the treatment of peri-implantitis; howe...

journal_title：Journal of periodontal research

authors： Fang D,Yuran S,Reches M,Catunda R,Levin L,Febbraio M

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Factors such as vascularization of the periodontium, inflammatory reactions and immune response affect the oral environment and ecology, decreasing host resistance and promoting the development of symptoms and the advancement of periodontal disease. Fatigue also influences the hypothalamic-pitu...

journal_title：Journal of periodontal research

authors： Nakada T,Kato T,Numabe Y

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The purpose of this study was to determine any difference between Porphyromonas gingivalis isolates from periodontally healthy sites as compared to those from diseased sites with respect to the ability to invade host cells. MATERIAL AND METHODS:Subgingival plaque samples were obtained from per...

journal_title：Journal of periodontal research

authors： Jandik KA,Bélanger M,Low SL,Dorn BR,Yang MC,Progulske-Fox A

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVES:Distinct periodontal phenotypes have been identified by cluster analysis, which is an explorative method with very low external validity. The aim of the present study was to investigate variance components of facial gingival thickness in young adults with mild gingivitis. MATERIAL AND METHODS:Thirty-three n...

journal_title：Journal of periodontal research

authors： Müller HP,Könönen E

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interleukin-6 (IL-6) is a key proinflammatory cytokine that has been considered to be important in the pathogenesis of periodontal disease. Therefore, host-modulatory agents directed at inhibiting IL-6 appear to be beneficial in terms of attenuating periodontal disease progression and potential...

journal_title：Journal of periodontal research

authors： Jin JY,Choi EY,Park HR,Choi JI,Choi IS,Kim SJ

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:T cells and their cytokines are believed to be key factors in periodontal disease and bone resorption. We previously showed that T cells transferred to nude mice were related to inflammatory bone resorption in vivo. However, it has not been clarified whether T cells can induce bone resorption i...

journal_title：Journal of periodontal research

authors： Yamaguchi M,Ukai T,Kaneko T,Yoshinaga M,Yokoyama M,Ozaki Y,Hara Y

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:During cyclosporine-induced gingival overgrowth, the homeostatic balance of gingival connective tissue is disrupted leading to fibrosis. Galectins are glycan-binding proteins that can modulate a variety of cellular processes including fibrosis in several organs. Here, we study the role of galec...

journal_title：Journal of periodontal research

authors： Smith PC,Metz C,de la Peña A,Oyanadel C,Avila P,Arancibia R,Vicuña L,Retamal C,Barake F,González A,Soza A

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In the oral cavity, the mucosal tissues may develop a number of different pathological conditions, such as inflammatory diseases (gingivitis, periodontitis) and autoimmune disorders (eg, oral lichen planus) that require therapy. The application of topical drugs is one common therapeutic approa...

journal_title：Journal of periodontal research

authors： Jager J,Obst K,Lohan SB,Viktorov J,Staufenbiel S,Renz H,Unbehauen M,Haag R,Hedtrich S,Teutloff C,Meinke MC,Danker K,Dommisch H

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To study the expression and role in vigabatrin (VGB)-induced gingival enlargement of Ki-67 antigen and p27KIP1, p21WAF1, and p53, proteins that activate or inhibit cell-cycle progression. MATERIALS AND METHODS:Six patients treated with VGB for partial epileptic seizures refractory to classic anticonvulsant t...

journal_title：Journal of periodontal research

authors： Mesa F,Aguilar M,Gonzalez-Moles MA,Guerrero A,Sanchez-Alvarez JC,Del Moral RG,O'Valle F

更新日期：2004-02-01 00:00:00

abstract：:Fibroblast function in gingival tissue is thought to be regulated by the local cellular environment--both the extracellular matrix and soluble factors. In an attempt to artificially re-create this situation fibroblasts have been cultured within 3-dimensional collagen gels in an environment more physiologically compara...

journal_title：Journal of periodontal research

authors： Irwin CR,Schor SL,Ferguson MW

更新日期：1994-09-01 00:00:00

abstract：:We have studied the polymorphonuclear leukocyte (PMN) phagocytosis of Porphyromonas gingivalis (Bacteroides gingivalis) and Prevotella intermedia (Bacteroides intermedius) in three-dimensional fibrin meshworks formed by either clotting human plasma or by clotting purified fibrinogen with human serum incorporated. PMN ...

journal_title：Journal of periodontal research

authors： Hurst TJ,Wilton JM

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The field of salivary diagnostics lacks an accepted and validated biomarker of alveolar bone remodeling. To address this, we examined levels of salivary biomolecules specifically associated with biological aspects of bone remodeling in subjects with chronic periodontitis in a case-control study...

journal_title：Journal of periodontal research

authors： Al-Sabbagh M,Alladah A,Lin Y,Kryscio RJ,Thomas MV,Ebersole JL,Miller CS

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Ciclosporin A (CsA)-induced gingival overgrowth is attributed to an exaggerated accumulation of extracellular matrix, which is mainly due to an increased expression of transforming growth factor-β1 (TGF-β1). Herein, the in vitro investigation of effects of overexpression of Smad7, a TGF-β1 sign...

journal_title：Journal of periodontal research

authors： Sobral LM,Aseredo F,Agostini M,Bufalino A,Pereira MC,Graner E,Coletta RD

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Irsogladine maleate counters gap junctional intercellular communication reduction induced by interleukin-8 or Actinobacillus actinomycetemcomitans in cultured human gingival epithelial cells. Interleukin-1 beta is involved in periodontal disease. Little is known, however, about the effect of in...

journal_title：Journal of periodontal research

authors： Fujita T,Ashikaga A,Shiba H,Kajiya M,Kishimoto A,Hirata R,Tsunekuni N,Hirono C,Kawaguchi H,Shiba Y,Kurihara H

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Nicotine, the main psychoactive component of tobacco, affects cell metabolism, proliferation, adhesion and, importantly, the osteogenic differentiation of fibroblasts. Approximately 15% of all orthodontic patients are adults among who one-fifth are smokers. Hence, it is necessary to have insig...

journal_title：Journal of periodontal research

authors： Yu W,Hu B,Shi X,Cao Z,Ren M,He Z,Lin J,Deng H,Hu R

更新日期：2018-08-01 00:00:00

abstract：:Black-pigmented bacteria which produce cytotoxic metabolic end-products and cell membrane-associated proteases have been reported to play an important role in the pathogenesis of periodontal diseases. These bacterial virulence factors can be modified by the environmental conditions including nutrients supplied various...

journal_title：Journal of periodontal research

authors： Saito K,Takahashi N,Horiuchi H,Yamada T

更新日期：2001-12-01 00:00:00

abstract：:Bursts of periodontal destruction are modelled as percolation-driven phase shift events. Percolation theory, though widely used to study the flow of liquids through porous nonliving materials (e.g., soils and rocks), can be applied to bacterial or toxicological penetration of living tissue in only an approximate sense...

journal_title：Journal of periodontal research

authors： Cohen ME

更新日期：1993-11-01 00:00:00

abstract：:Hereditary gingival fibromatosis (HGF) is an oral condition characterized by the enlargement of the gingiva of both the maxilla and mandible. To study the cell proliferation index of fibroblasts from HGF and normal gingiva (NG), cell cultures from 4 members of the same family with HGF and from 4 healthy patients were ...

journal_title：Journal of periodontal research

authors： Coletta RD,Almeida OP,Graner E,Page RC,Bozzo L

更新日期：1998-11-01 00:00:00