Abstract：
:Bursts of periodontal destruction are modelled as percolation-driven phase shift events. Percolation theory, though widely used to study the flow of liquids through porous nonliving materials (e.g., soils and rocks), can be applied to bacterial or toxicological penetration of living tissue in only an approximate sense. However, it seems necessary that some mechanism, fundamentally similar to the percolation phase shift, is required to adequately account for bursts. Percolation theory is therefore offered as a framework for considering such events. A principal finding of percolation theory is the existence of percolation thresholds, such that when P, the independent probability that a subregion is susceptible to an invading substance, is above the threshold, the region will percolate or allow flow through, and when P is below the threshold the region will not percolate. This instantaneous transition, from a structure that will permit percolation to one that will not, is described as a phase shift. In addition, the value of P is postulated to depend on multiple factors which might constitute a chaotic system. The nonproportionality of a percolation phase shift and the nonpredictability of any specific chaotic event suggest that reliable burst predictors may, in theory, not be possible at the level of the individual site.
journal_name
J Periodontal Resjournal_title
Journal of periodontal researchauthors
Cohen MEsubject
Has Abstractpub_date
1993-11-01 00:00:00pages
429-36issue
6 Pt 1eissn
0022-3484issn
1600-0765journal_volume
28pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVE:The gingival epithelium is a first line of defense against bacterial challenge. E-cadherin (E-cad) plays an important role in cell-cell adhesion as a barrier in the epithelium. Recently, a decrease in the expression of E-cad has been observed in inflamed gingival tissue. The aims of this study ...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/jre.12367
更新日期：2017-02-01 00:00:00
abstract：:This study investigated the cell surface expression of CD11b (Mo 1, Mac-1, CR 3) by neutrophils (PMNs) from human crevicular fluid (CF-PMNs). CD11b expression on CF-PMNs was compared, using flow cytometry, to that on peripheral blood PMNs (PB-PMNs) isolated simultaneously from the same subjects. CD11b expression by CF...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.1991.tb01631.x
更新日期：1991-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Although induction of heme oxygenase-1 by H2O2 has been reported, the protective role of heme oxygenase-1 against the cytotoxic and osteoclastogenic effects of H2O2 have not been elucidated in human periodontal ligament cells. The aim of this work was to investigate the defense mechanism of hem...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2006.00953.x
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Studies have shown that bacterial plaque and the associated gingival inflammation increase the severity of gingival overgrowth induced by cyclosporine-A (CsA). This in vitro study aimed to evaluate the effect of CsA on the activities of MMPs from the co-culture of human gingival fibroblasts and...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2011.01450.x
更新日期：2012-08-01 00:00:00
abstract：:The titre and avidity of IgG antibodies to Porphyromonas gingivalis whole cells and a 47 kDa cell surface protein were determined in serum samples taken from 20 subjects with adult periodontitis and 20 controls, matched for age, gender, ethnic origin and oral hygiene status. Antibody titres were measured by ELISA and ...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.1997.tb01379.x
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The use of cyclosporine A induces fibrous enlargement of the gingival connective tissue. Existing treatment modalities, although effective, do not necessarily prevent the recurrence of the lesion. Emerging evidence indicates that tanshinone IIA (Tan IIA) could effectively attenuate a variety of...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/jre.12335
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Ciclosporin A (CsA)-induced gingival overgrowth is attributed to an exaggerated accumulation of extracellular matrix, which is mainly due to an increased expression of transforming growth factor-β1 (TGF-β1). Herein, the in vitro investigation of effects of overexpression of Smad7, a TGF-β1 sign...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2011.01412.x
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:Races and Gm(23) allotypes can modify the serum levels of IgG subclasses. The average serum levels of IgG subclasses of African-Americans have been reported to be higher than those of Caucasians in both healthy young adults and patients with aggressive periodontitis; Gm(23)-positive subjects generally had hi...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1034/j.1600-0765.2003.00675.x
更新日期：2003-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to design a tripolyphosphate-chitosan cross-linked tetracycline-containing (TPP-TC) sponge that slowly releases tetracycline, for future periodontal applications. MATERIAL AND METHODS:Chitosan sponge was made by freezing and drying 2.5% chitosan solution. Tripolyphosp...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2007.01045.x
更新日期：2008-12-01 00:00:00
abstract：:Neuropeptides, including substance P (SP) may play a role in neurogenic inflammation. Although SP-immunoreactive (SP-IR) axons are known to be present within the oral mucosa (OM) and salivary glands, the functional significance of SP in oral mucosa and sublingual salivary gland (SLG) is not fully understood. The prese...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.1995.tb01271.x
更新日期：1995-05-01 00:00:00
abstract：BACKGROUND:Alveolar bone resorption is a characteristic feature of periodontal diseases and involves the removal of both the mineral and organic constituents of the bone matrix, which is caused by either multinucleated osteoclast cells or matrix metalloproteinases (MMPs). The gram-negative bacterium, Porphyromonas ging...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2004.00743.x
更新日期：2004-10-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Autoimmune diseases, including atherosclerosis, diabetes mellitus and rheumatoid arthritis, can be triggered and aggravated by the pathogen-driven antigenic peptide from Porphyromonas gingivalis HSP60. P. gingivalis is the major pathogen of chronic periodontitis, which is a global epidemic prev...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2012.01501.x
更新日期：2012-12-01 00:00:00
abstract：:Recent reports suggest that specific serum IgG subclasses are a feature of several forms of periodontitis. GCF antibodies are both serum-derived and locally produced by the abundant plasma cells of the diseased periodontal tissue. Previous work has shown that crevicular fluid (GCF) levels of IgG may be reduced in acti...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.1997.tb01401.x
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Little is known about the factors that affect the microbial composition of supragingival biofilms. This study was designed to examine the relationship between total DNA probe counts of supragingival biofilm samples, clinical parameters and supragingival biofilm composition. MATERIAL AND METHOD...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2008.01154.x
更新日期：2009-08-01 00:00:00
abstract：:The role of bacteria in the initiation of periodontitis is well-documented and the end result, destruction of the alveolar bone and periodontal connective tissue, is readily observed; but the events occurring between these two points in time remain obscure and are the focus of this paper. Bacteria induce tissue destru...
journal_title：Journal of periodontal research
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0765.1991.tb01649.x
更新日期：1991-05-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:This study analyzed the interaction of Porphyromonas gingivalis ATCC 33277 and Aggregatibacter actinomycetemcomitans Y4 with peripheral blood polymorphonuclear neutrophils taken from patients with aggressive periodontitis and chronic periodontitis. MATERIAL AND METHODS:Peripheral blood polymor...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2008.01113.x
更新日期：2009-06-01 00:00:00
abstract：:The onset and progression of periodontal disease is associated with significant changes in the epithelial component of the attachment complex. From the early to the advanced stages of periodontal disease increased epithelial cell proliferation, migration and invasion into the surrounding connective tissue takes place....
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：
更新日期：2002-02-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Biofilm formation occurs through the events of cooperative growth and competitive survival among multiple species. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans are important periodontal pathogens. The aim of this study was to demonstrate competitive or cooperative interact...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/jre.12006
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Lipopolysaccharide (LPS) on the cell wall of periodontal pathogens is a major mediator of the inflammatory response and can enhance alveolar bone resorption in periodontitis. Bone sialoprotein is an early marker of osteoblast differentiation. The proinflammatory cytokine, interleukin-8 (IL-8), ...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/jre.12193
更新日期：2015-04-01 00:00:00
abstract：:Interleukin-8 (IL-8) is believed to play an important role in the pathogenesis of various forms of periodontitis. In addition, the anti-IL-8 autoantibody has been recently recognized as a potent modulator of IL-8 function. In the current study, the concentrations of IL-8 and its autoantibody in gingival crevicular flu...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1034/j.1600-0765.2003.02001.x
更新日期：2003-02-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Periodontal disease has been described as playing a role in the atherosclerosis process, and its relation with intimal thickness and vascular endothelial function (EF) has been investigated. The present study sought to determine whether there are differences in parameters of arterial stiffness ...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/jre.12376
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Enamel matrix derivative (EMD) is used clinically to promote periodontal tissue regeneration, and it has been reported that EMD can induce the formation of osteoclasts in mouse marrow cultures. In the present study, we investigated the mechanisms of EMD-induced osteoclast formation using a mous...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2005.00868.x
更新日期：2006-08-01 00:00:00
abstract：:The aim of this study was to conduct a systematic review to compare the clinical outcomes of two different resorbable collagen membranes in terms of regenerated bone volume, postoperative complications and membrane degradation during bone regeneration procedures. Randomized controlled trials (RCT) or controlled trials...
journal_title：Journal of periodontal research
pub_type： 杂志文章,评审
doi：10.1111/jre.12470
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:It has been suggested that aggressive periodontitis has a genetic basis. Monocyte chemoattractant protein 1 (MCP-1) plays a critical role in the recruitment of monocytes and the development of periodontitis. The -2518MCP-1(A/G) polymorphism has been implicated as a risk or susceptibility factor...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2011.01426.x
更新日期：2012-06-01 00:00:00
abstract：:Previous observations suggest that interleukin-1 (IL-1) may play an important role in the progression of periodontitis. In the present study, we investigated whether a cell-associated IL-1 alpha (CAIL-1 alpha) produced in human gingival fibroblasts (HGF) induces biological activities related to the progression of peri...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.1996.tb00503.x
更新日期：1996-07-01 00:00:00
abstract：:The diagnosis of periodontal disease is commonly based on objective evaluations of the patient's medical/dental history as well as clinical and radiographic examinations. However, periodontal disease should also be evaluated subjectively through measures that quantify its impact on oral health-related quality of life....
journal_title：Journal of periodontal research
pub_type： 杂志文章,评审
doi：10.1111/jre.12436
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:High-mobility-group box 1 functions as a late-phase inflammatory mediator. It can be released extracellularly by macrophages and necrotic cells through lipopolysaccharide and tumor necrosis factor-alpha. The objective of this study was to clarify the source of high-mobility-group box 1 in chron...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2007.00996.x
更新日期：2008-02-01 00:00:00
abstract：:Volume and amounts of myeloperoxidase (MPO), lactoferrin (LF), aryl sulfatase (AS) and lactate dehydrogenase (LDH) were measured in gingival crevicular fluid (GCF) collected from the mesial and distal proximal surfaces of the premolars and first and second molars of 3 subject groups. Group assignment was based on subj...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.1992.tb01819.x
更新日期：1992-09-01 00:00:00
abstract：:The 160, 190 and 270 kDa outer sheath proteases of Treponema denticola ATCC 35404 were found to be multiple forms of the major 91 kDa phenylalanine protease (PAP) by immunoblotting using anti-91 kDa specific antibodies. Multiple forms of the phenylalanine protease were also found in 2 other T. denticola strains studie...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.1999.tb02253.x
更新日期：1999-07-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Arecoline, an arecanut alkaloid present in the saliva of betel quid chewers, has been implicated in the pathogenesis of a variety of inflammatory oral diseases, including oral submucous fibrosis and periodontitis. To understand the molecular basis of arecoline action in epithelial changes assoc...
journal_title：Journal of periodontal research
pub_type： 杂志文章
doi：10.1111/j.1600-0765.2008.01176.x
更新日期：2009-10-01 00:00:00
