Keratinocyte growth factor (KGF)-1 and -2 protein and gene expression in human gingival fibroblasts.

abstract：BACKGROUND AND OBJECTIVE:Postranslational modification of proteins can lead to the production of autoantibodies and loss of immune tolerance. This process has been hypothesised to be a critical factor in the pathogenesis of rheumatoid arthritis. The objective of this study was to demonstrate that inflamed human gingiva...

journal_title：Journal of periodontal research

authors： Bright R,Thiele GM,Manavis J,Mikuls TR,Payne JB,Bartold PM

更新日期：2018-02-01 00:00:00

abstract：:The present study was carried out to examine the ultrastructural localization of laminin and type-IV collagen in the junctional epithelium of rat molar gingiva by means of the indirect immunoperoxidase method. Intense laminin reaction occurred in both the internal and the external basal laminae. Laminin reaction produ...

journal_title：Journal of periodontal research

authors： Sawada T,Yamamoto T,Yanagisawa T,Takuma S,Hasegawa H,Watanabe K

更新日期：1990-11-01 00:00:00

abstract：:Quantitative assessment of osseous changes attributable to periodontal disease is made possible by digital subtraction radiography. Tissues through which x rays travel to produce dental radiographs essential to this process alter the energy spectrum of the beam such that calibration errors result when densitometry is ...

journal_title：Journal of periodontal research

authors： Webber RL,Tzukert A,Ruttimann U

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The use of cyclosporine A induces fibrous enlargement of the gingival connective tissue. Existing treatment modalities, although effective, do not necessarily prevent the recurrence of the lesion. Emerging evidence indicates that tanshinone IIA (Tan IIA) could effectively attenuate a variety of...

journal_title：Journal of periodontal research

authors： Ma S,Liu W,Liu P,Liu J,Chen L,Qin C

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Arecoline, an arecanut alkaloid present in the saliva of betel quid chewers, has been implicated in the pathogenesis of a variety of inflammatory oral diseases, including oral submucous fibrosis and periodontitis. To understand the molecular basis of arecoline action in epithelial changes assoc...

journal_title：Journal of periodontal research

authors： Thangjam GS,Kondaiah P

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Elevated nitric oxide (NO) has been associated with destructive periodontal disease. The aim of the present study was to test the hypothesis that exogenous NO may inhibit a protective immune response to Aggregatibacter actinomycetemcomitans lipopolysaccharide (LPS) in a murine model. MATERIAL ...

journal_title：Journal of periodontal research

authors： Sosroseno W,Bird PS,Seymour GJ

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:Previous studies have suggested an association between chronic infection and cardiovascular disease, and combined infection/inflammation is frequently related with hypertriglyceridemia, which may be a risk factor of cardiovascular disease. In fact, experimental transient or intermittent administration of lip...

journal_title：Journal of periodontal research

authors： Uchiumi D,Kobayashi M,Tachikawa T,Hasegawa K

更新日期：2004-04-01 00:00:00

abstract：:This study was designed to study wound strength at the dentine/connective tissue interface and at the bone/connective tissue interface following full thickness flap surgery. Flaps of uniform dimension were outlined in four young adult beagle dogs using a standardised double bladed knife and vertical incisions 10 mm ap...

journal_title：Journal of periodontal research

authors： Werfully S,Areibi G,Toner M,Bergquist J,Walker J,Renvert S,Claffey N

更新日期：2002-10-01 00:00:00

abstract：:The 3 human salivary cystatins S, SA and SN are multifunctional proteins that possess a cysteine protease inhibitory property, but their ability to act as such is very different (SN > SA > S). One form, S, also appears to possess antibacterial properties towards the bacterium Porphyromonas gingivalis, often associated...

journal_title：Journal of periodontal research

authors： Baron AC,Gansky SA,Ryder MI,Featherstone JD

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Long noncoding RNAs (lncRNAs) play critical and complex roles in regulating various biological processes of periodontitis. This bioinformatic study aims to construct a putative competing endogenous RNA (ceRNA) network by integrating lncRNA, miRNA and mRNA expression, based on high-throughput R...

journal_title：Journal of periodontal research

authors： Li S,Liu X,Li H,Pan H,Acharya A,Deng Y,Yu Y,Haak R,Schmidt J,Schmalz G,Ziebolz D

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The expression of A Disintegrin and Metalloproteinase 8 (ADAM8) is associated with several inflammatory diseases. Elevated ADAM8 levels have been shown in gingival crevicular fluid of patients with chronic periodontitis. The objective of this study was to investigate ADAM8 expression in chroni...

journal_title：Journal of periodontal research

authors： Aung WPP,Chotjumlong P,Pata S,Montreekachon P,Supanchart C,Khongkhunthian S,Sastraruji T,Krisanaprakornkit S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Neutrophils are the primary white blood cells that are recruited to fight the initial phases of microbial infections. While healthy norms have been determined for circulating blood neutrophil counts in order to identify patients with suspected systemic infections, the levels of oral neutrophils...

journal_title：Journal of periodontal research

authors： Landzberg M,Doering H,Aboodi GM,Tenenbaum HC,Glogauer M

更新日期：2015-06-01 00:00:00

abstract：:We have reported recently that increased expression of membrane alkaline phosphatase (ALP) activity is a phenotypical characteristic of gingival fibroblasts located in chronic inflammatory periodontal lesions. To understand the cellular properties of these cells, we isolated ALP-positive gingival fibroblasts from pati...

journal_title：Journal of periodontal research

authors： Abe T,Hara Y,Abe Y,Aida Y,Maeda K

更新日期：1996-05-01 00:00:00

abstract：:The titre and avidity of IgG antibodies to Porphyromonas gingivalis whole cells and a 47 kDa cell surface protein were determined in serum samples taken from 20 subjects with adult periodontitis and 20 controls, matched for age, gender, ethnic origin and oral hygiene status. Antibody titres were measured by ELISA and ...

journal_title：Journal of periodontal research

authors： Benjamin PA,Rogers PA,U S,Johnson NW,Cole MF,Curtis MA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Races and Gm(23) allotypes can modify the serum levels of IgG subclasses. The average serum levels of IgG subclasses of African-Americans have been reported to be higher than those of Caucasians in both healthy young adults and patients with aggressive periodontitis; Gm(23)-positive subjects generally had hi...

journal_title：Journal of periodontal research

authors： Chung HY,Lu HC,Chen WL,Lu CT,Yang YH,Tsai CC

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:For ethical reasons it is becoming increasingly more difficult to obtain, from clinical studies, histological data on infrabony defects treated with guided tissue regeneration (GTR) techniques. The aim of this systematic review was to find the value of extrapolating animal data on treatment of ...

journal_title：Journal of periodontal research

authors： Yen CC,Tu YK,Chen TH,Lu HK

更新日期：2014-08-01 00:00:00

abstract：:Four rough-surfaced (R) and three smooth-surfaced (S) clinical isolates of Capnocytophaga obtained from the subgingival plaque of periodontitis patients were studied for their peptidase and protease profiles. The results were compared with those obtained with C. gingivalis (which has a smooth morphology). All cell ext...

journal_title：Journal of periodontal research

authors： Söderling E,Mäkinen PL,Syed S,Mäkinen KK

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate whether a peptide-based coating can prevent the adhesion of Porphyromonas gingivalis, a key human pathogen associated with periodontitis and peri-implantitis. BACKGROUND:Nonsurgical and surgical interventions have been used for the treatment of peri-implantitis; howe...

journal_title：Journal of periodontal research

authors： Fang D,Yuran S,Reches M,Catunda R,Levin L,Febbraio M

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:It remains controversial whether or not the junctional epithelium cells that are directly attached to teeth migrate on the enamel surface, as those cells are able to adhere firmly to the enamel. The aim of this study was to investigate the expression patterns of laminin gamma(2), integrin beta(...

journal_title：Journal of periodontal research

authors： Sugisawa M,Masaoka T,Enokiya Y,Muramatsu T,Hashimoto S,Yamada S,Shimono M

更新日期：2010-04-01 00:00:00

abstract：:Clinical trials designed to estimate the sensitivity and specificity of periodontal diagnostic tests often use multiple sites per patient as experimental units of analyses. Since site-specific test results within a patient are dependent observations, a correlated binomial model should be employed to estimate the sensi...

journal_title：Journal of periodontal research

authors： Hujoel PP,Moulton LH,Loesche WJ

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interleukin-6 (IL-6) is a key proinflammatory cytokine that has been considered to be important in the pathogenesis of periodontal disease. Therefore, host-modulatory agents directed at inhibiting IL-6 appear to be beneficial in terms of attenuating periodontal disease progression and potential...

journal_title：Journal of periodontal research

authors： Jin JY,Choi EY,Park HR,Choi JI,Choi IS,Kim SJ

更新日期：2013-12-01 00:00:00

abstract：:This study compared a rapid, colorimetric DNA probe assay designed to be performed in a dental office within 40 min, with anaerobic culture and indirect immunofluorescence microscopy (IFM) for detection of Bacteroides forsythus and Porphyromonas gingivalis in subgingival plaque samples. The DNA probe assay used the Pe...

journal_title：Journal of periodontal research

authors： Tanner AC,Maiden MF,Zambon JJ,Thoren GS,Kent RL Jr

更新日期：1998-02-01 00:00:00

abstract：:Though cementum of the tooth root is critical for periodontal structure and tooth attachment and function, this tissue was not discovered and characterized on human teeth until a full century later than enamel and dentin. Early observations from the seventeenth to the nineteenth centuries by Marcello Malpighi, Antonie...

journal_title：Journal of periodontal research

authors： Foster BL

更新日期：2017-08-01 00:00:00

abstract：:The effectiveness of an ideal antimicrobial agent depends on its ability to kill microbes with minimal toxicity to host cells. Depending on the treatment regimen, antimicrobial agents come into contact with host cells for various intervals of time. Sanguinarium (SANG), chlorhexidine (CHX) and tetracycline (TET) are 3 ...

journal_title：Journal of periodontal research

authors： Agarwal S,Piesco NP,Peterson DE,Charon J,Suzuki JB,Godowski KC,Southard GL

更新日期：1997-04-01 00:00:00

abstract：:Fibroblast function in gingival tissue is thought to be regulated by the local cellular environment--both the extracellular matrix and soluble factors. In an attempt to artificially re-create this situation fibroblasts have been cultured within 3-dimensional collagen gels in an environment more physiologically compara...

journal_title：Journal of periodontal research

authors： Irwin CR,Schor SL,Ferguson MW

更新日期：1994-09-01 00:00:00

abstract：:In general, randomized clinical trials (RCT) in dentistry involve longitudinal observations. In such studies, the total cost is a function of the number of study subjects and visits, the study duration, and the type and number of examinations at each visit. In this paper, we derived the minimum cost design for longitu...

journal_title：Journal of periodontal research

authors： Hefti AF,Yang MC

更新日期：1999-04-01 00:00:00

abstract：:Nearly 70-75% of patients with localized juvenile periodontitis (JP) have abnormal polymorphonuclear leukocytic (PMN) chemotaxis. The objective of this study was to determine whether the lower chemotactic response in PMNs from JP patients is associated with a defect in intracellular signal transduction, as measured by...

journal_title：Journal of periodontal research

authors： Agarwal S,Reynolds MA,Duckett LD,Suzuki JB

更新日期：1989-03-01 00:00:00

abstract：:The pattern of cytokeratin expression has been extensively described in the normal and inflamed periodontium. However, there is no information regarding the pattern of cytokeratin expression in the periodontium which has been reformed following regenerative periodontal surgery. The aim of the present investigation was...

journal_title：Journal of periodontal research

authors： Sculean A,Berakdar M,Pahl S,Windisch P,Brecx M,Reich E,Donos N

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVES:Chronic periodontitis is a bone destructive inflammatory disease with an adverse impact on general health and suggested underlying factors in common with osteoporosis. A few studies have examined the possible relationship between chronic periodontitis and osteoporosis; however, the results remain inconclusiv...

journal_title：Journal of periodontal research

authors： Mau LP,Kuan YC,Tsai YC,Lin JJ,Huynh-Ba G,Weng PW,Shieh YS,Cheng WC,Huang RY

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Porphyromonas gingivalis, a black-pigmented, gram-negative anaerobe, is found in periodontitis lesions and its presence in subgingival plaque significantly increases the risk for periodontitis. We have previously shown that patients with aggressive forms of periodontitis that are seropositive for P. gingival...

journal_title：Journal of periodontal research

authors： Califano JV,Chou D,Lewis JP,Rogers JD,Best AM,Schenkein HA

更新日期：2004-08-01 00:00:00