Patients with chronic periodontitis present increased risk for osteoporosis: A population-based cohort study in Taiwan.

abstract：:Diploid fibroblasts obtained from explants of human gingiva and maintained in vitro undergo a several-fold decrease in protein and collagen synthesis as a function of increasing donor age. Using drug-induced gingival hyperplasia as a model, we performed experiments to learn whether fibroblasts derived from hyperplasti...

journal_title：Journal of periodontal research

authors： Johnson BD,Narayanan AS,Pieters HP,Page RC

更新日期：1990-03-01 00:00:00

abstract：:Colonization or emergence of microbial pathogens may result in tissue destruction by activation of one or more of five distinct host degradative pathways (matrix metalloproteinase pathway, plasminogen-dependent pathway, phagocytic pathway, PMN-serine proteinase pathway and osteoclastic bone resorption) or by direct cl...

journal_title：Journal of periodontal research

authors： Birkedal-Hansen H

更新日期：1993-11-01 00:00:00

abstract：:To document the effect of hypophysectomy and growth hormone replacement on the ultrastructure of cementogenesis in the developing rat third molar, 12 female Wistar rats were randomly allocated to normal control, hypophysectomized or hypophysectomized plus human growth hormone (for 10 days) treatment groups. The result...

journal_title：Journal of periodontal research

authors： Clayden AM,Young WG,Zhang CZ,Harbrow D,Romaniuk K,Waters MJ

更新日期：1994-07-01 00:00:00

abstract：:In the present study, the effect of bacterial protease on the periodontal tissues in rats was investigated histologically and histometrically. In the control group, 0.03 ml distilled water was applied to the lingual marginal gingiva of the mandibular incisor while, in the experimental group, 0.03 ml bacterial protease...

journal_title：Journal of periodontal research

authors： Suzumura Y,Kameyama Y,Mizutani M,Kato M,Kondo K,Mabuchi R

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:beta defensin antimicrobial peptides are important in epithelial innate immunity, and their differential expression is associated with periodontal diseases. The aims of this study were to determine the mRNA expression of human beta defensin-1 and -2 in the gingival tissue of patients with gingi...

journal_title：Journal of periodontal research

authors： Vardar-Sengul S,Demirci T,Sen BH,Erkizan V,Kurulgan E,Baylas H

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Few studies estimated the joint effect of implant design (length and diameter), peri-implant, and occlusal variables on early marginal bone loss. The monitoring of these factors during the first year after implant loading may be effective in preventing early implant failure. This prospective lo...

journal_title：Journal of periodontal research

authors： Radaelli MTB,Federizzi L,Nascimento GG,Leite FRM,Boscato N

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Proinflammatory cytokines such as interleukin-1beta are known to be synthesized in oral gingivitis and periodontitis and lead to the activation of the transcription factor nuclear factor-kappaB (NF-kappaB). Although numerous effects of interleukin-1beta on mesenchymal cells are known, e.g. up-regu...

journal_title：Journal of periodontal research

authors： Steinberg T,Dannewitz B,Tomakidi P,Hoheisel JD,Müssig E,Kohl A,Nees M

更新日期：2006-10-01 00:00:00

abstract：:Vascularization of the periodontal ligament was examined in developing upper first molars of rats from 5 to 30 d after birth with light and scanning electron microscopy. Formation of the vascular network in the periodontal ligament (PDL) started with the beginning of root formation. The PDL vessels derived from the ba...

journal_title：Journal of periodontal research

authors： Tsukada H,Ishikawa H,Nakamura S,Yoshida S

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Obesity has been implicated as a risk factor for several chronic health conditions. Recent studies have reported a relationship between obesity and periodontitis, but few studies have investigated this relationship in adolescents. The purpose of the present study was to investigate the relation...

journal_title：Journal of periodontal research

authors： Ekuni D,Yamamoto T,Koyama R,Tsuneishi M,Naito K,Tobe K

更新日期：2008-08-01 00:00:00

abstract：:This study uses cytokeratins (CK) as markers to investigate the phenotype of the junctional epithelium (JE) in partially erupted human teeth. The gingival samples, which were clinically healthy, were carefully dissected from the teeth. Cryostat sections were cut for histological staining, immunofluorescence microscopy...

journal_title：Journal of periodontal research

authors： Feghali-Assaly M,Sawaf MH,Serres G,Forest N,Ouhayoun JP

更新日期：1994-05-01 00:00:00

abstract：:Cyclosporine (CsA) is a selective immunosuppressant widely used in clinical therapy. Like phenytoin and nifedipine, the drug is associated with gingival overgrowth. This study considers the interaction of CsA and prostaglandin I2 (PGI2), in particular the action of the drug on gingival tissue in vitro and in vivo. The...

journal_title：Journal of periodontal research

authors： Nell A,Matejka M,Solar P,Ulm C,Sinzinger H

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Salvia miltiorrhiza Bunge (Labiatae), or Danshen, is a Chinese medicine used for treatment of cardiac diseases by improving blood circulation and inhibiting inflammatory responses. In this study, we aimed to determine whether an ethanol extract of S. miltiorrhiza can ameliorate tissue damage ca...

journal_title：Journal of periodontal research

authors： Chiang CY,Tsai HT,Chang WL,Chin YT,Chang WJ,Tu HP,Chiu HC,Fu E

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Smoking cigarettes increases the risk of oral tissue damage leading to periodontal disease. Gingival fibroblasts, the predominant cell type inhabiting gingival connective tissue, play a critical role in remodeling and maintaining gingival structure. The objective of this study was to investigat...

journal_title：Journal of periodontal research

authors： Alamri A,Semlali A,Jacques É,Alanazi M,Zakrzewski A,Chmielewski W,Rouabhia M

更新日期：2015-08-01 00:00:00

abstract：:The role of bacteria in the initiation of periodontitis is well-documented and the end result, destruction of the alveolar bone and periodontal connective tissue, is readily observed; but the events occurring between these two points in time remain obscure and are the focus of this paper. Bacteria induce tissue destru...

journal_title：Journal of periodontal research

authors： Page RC

更新日期：1991-05-01 00:00:00

abstract：:The titre and avidity of IgG antibodies to Porphyromonas gingivalis whole cells and a 47 kDa cell surface protein were determined in serum samples taken from 20 subjects with adult periodontitis and 20 controls, matched for age, gender, ethnic origin and oral hygiene status. Antibody titres were measured by ELISA and ...

journal_title：Journal of periodontal research

authors： Benjamin PA,Rogers PA,U S,Johnson NW,Cole MF,Curtis MA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Lipopolysaccharide (LPS) on the cell wall of periodontal pathogens is a major mediator of the inflammatory response and can enhance alveolar bone resorption in periodontitis. Bone sialoprotein is an early marker of osteoblast differentiation. The proinflammatory cytokine, interleukin-8 (IL-8), ...

journal_title：Journal of periodontal research

authors： Zhang Y,Li X

更新日期：2015-04-01 00:00:00

abstract：:The 3 human salivary cystatins S, SA and SN are multifunctional proteins that possess a cysteine protease inhibitory property, but their ability to act as such is very different (SN > SA > S). One form, S, also appears to possess antibacterial properties towards the bacterium Porphyromonas gingivalis, often associated...

journal_title：Journal of periodontal research

authors： Baron AC,Gansky SA,Ryder MI,Featherstone JD

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:After tooth formation is complete, it is suggested that continuity exists between the epithelial cell rests of Malassez (ERM), reduced enamel epithelium (REE) and subsequently the junctional epithelium. However, the junctional epithelium was reported to differ from REE and ERM. The developmenta...

journal_title：Journal of periodontal research

authors： Li S,Ge S,Yang P

更新日期：2015-12-01 00:00:00

abstract：:The periodontium is a highly hierarchically organized organ composed of gingiva, alveolar bone, periodontal ligament and cementum. Periodontitis leads to the destruction of hard and soft tissues ultimately leading to a loss of the teeth supporting apparatus. Current treatments are capable of limiting the disease progr...

journal_title：Journal of periodontal research

authors： Staples RJ,Ivanovski S,Vaquette C

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Following tooth extraction, bone resorption is especially severe in cases complicated with buccal dehiscence bone defects. To minimize this, various bone graft materials have been used for alveolar ridge preservation. This study aimed to evaluate additional effects of the concomitant use of rec...

journal_title：Journal of periodontal research

authors： Fukuba S,Akizuki T,Matsuura T,Okada M,Nohara K,Hoshi S,Shujaa Addin A,Iwata T,Izumi Y

更新日期：2020-12-12 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Little is known about the factors that affect the microbial composition of supragingival biofilms. This study was designed to examine the relationship between total DNA probe counts of supragingival biofilm samples, clinical parameters and supragingival biofilm composition. MATERIAL AND METHOD...

journal_title：Journal of periodontal research

authors： Haffajee AD,Teles RP,Patel MR,Song X,Veiga N,Socransky SS

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Occlusal trauma is an important factor that influences the progression of periodontitis, but it is unclear whether occlusal trauma influences periodontal destruction at the onset of periodontitis. We established an experimental periodontitis model with both site-specific loss of attachment and ...

journal_title：Journal of periodontal research

authors： Nakatsu S,Yoshinaga Y,Kuramoto A,Nagano F,Ichimura I,Oshino K,Yoshimura A,Yano Y,Hara Y

更新日期：2014-06-01 00:00:00

abstract：:We have reported recently that increased expression of membrane alkaline phosphatase (ALP) activity is a phenotypical characteristic of gingival fibroblasts located in chronic inflammatory periodontal lesions. To understand the cellular properties of these cells, we isolated ALP-positive gingival fibroblasts from pati...

journal_title：Journal of periodontal research

authors： Abe T,Hara Y,Abe Y,Aida Y,Maeda K

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Periodontitis is an increasingly prevalent complication of diabetes mellitus (known as diabetes mellitus-associated periodontitis), and 25-hydroxyvitamin D3 (25VD3 ) was recently found to be a critical regulator of innate immunity in this disease, but the underlying mechanisms remain poorly und...

journal_title：Journal of periodontal research

authors： Zhang P,Zhang W,Zhang D,Wang M,Aprecio R,Ji N,Mohamed O,Li Y,Ding Y,Wang Q

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The origin of cells in the mature periodontium, and the location of their progenitors, are still unknown. It is also unknown whether inflammation influences the number and distribution of these cells within the periodontium. Molecules such as STRO-1, CD146 and CD44 have been identified on a var...

journal_title：Journal of periodontal research

authors： Chen SC,Marino V,Gronthos S,Bartold PM

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Chronic infections have been reported to be risk factors for coronary heart disease and ischemic stroke. However, the association of coronary heart disease and ischemic stroke with periodontal disease, which is also a chronic inflammatory disease, needs to be evaluated. The present case-control...

journal_title：Journal of periodontal research

authors： Pradeep AR,Hadge P,Arjun Raju P,Shetty SR,Shareef K,Guruprasad CN

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The purpose of this study was to determine any difference between Porphyromonas gingivalis isolates from periodontally healthy sites as compared to those from diseased sites with respect to the ability to invade host cells. MATERIAL AND METHODS:Subgingival plaque samples were obtained from per...

journal_title：Journal of periodontal research

authors： Jandik KA,Bélanger M,Low SL,Dorn BR,Yang MC,Progulske-Fox A

更新日期：2008-10-01 00:00:00

abstract：:The adherence of Actinomyces naeslundii to human buccal mucosa is mediated by specific interactions between the bacterial cell surface fimbriae and complementary beta-linked galactoside receptors on the epithelial cell surface. The buccal mucosa and the bacteria that colonize its surface are constantly bathed in saliv...

journal_title：Journal of periodontal research

authors： Babu JP,Dabbous MK,Abraham SN

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Studies have shown that bacterial plaque and the associated gingival inflammation increase the severity of gingival overgrowth induced by cyclosporine-A (CsA). This in vitro study aimed to evaluate the effect of CsA on the activities of MMPs from the co-culture of human gingival fibroblasts and...

journal_title：Journal of periodontal research

authors： Kuo PJ,Tu HP,Chin YT,Lu SH,Chiang CY,Chen RY,Fu E

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:It has been suggested that aggressive periodontitis has a genetic basis. Monocyte chemoattractant protein 1 (MCP-1) plays a critical role in the recruitment of monocytes and the development of periodontitis. The -2518MCP-1(A/G) polymorphism has been implicated as a risk or susceptibility factor...

journal_title：Journal of periodontal research

authors： Zhu XL,Meng HX,Zhang L,Xu L,Chen ZB,Shi D,Feng XH,Zhang X

更新日期：2012-06-01 00:00:00