Long junctional epithelium produced by application of bacterial protease in rats.

abstract：BACKGROUND AND OBJECTIVE:Irsogladine maleate counters gap junctional intercellular communication reduction induced by interleukin-8 or Actinobacillus actinomycetemcomitans in cultured human gingival epithelial cells. Interleukin-1 beta is involved in periodontal disease. Little is known, however, about the effect of in...

journal_title：Journal of periodontal research

authors： Fujita T,Ashikaga A,Shiba H,Kajiya M,Kishimoto A,Hirata R,Tsunekuni N,Hirono C,Kawaguchi H,Shiba Y,Kurihara H

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:Heat shock protein (HSP) can be utilized as a vaccine to cross-protect against multiple pathogenic species. The present study was performed to evaluate Porphyromonas gingivalis heat shock protein 60 (HSP60) as a vaccine candidate to inhibit multiple bacteria-induced alveolar bone loss. MATERIAL AND METHODS:...

journal_title：Journal of periodontal research

authors： Lee JY,Yi NN,Kim US,Choi JS,Kim SJ,Choi JI

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Adipocyte fatty acid-binding protein (A-FABP) is expressed in adipocytes, macrophages and microvascular endothelial cells, and it plays a central role in inflammation, atherosclerosis and metabolic responses. This pilot study investigated the effect of nonsurgical periodontal therapy on the ser...

journal_title：Journal of periodontal research

authors： Li X,Tse HF,Yiu KH,Zhang C,Jin LJ

更新日期：2013-06-01 00:00:00

abstract：:The titre and avidity of IgG antibodies to Porphyromonas gingivalis whole cells and a 47 kDa cell surface protein were determined in serum samples taken from 20 subjects with adult periodontitis and 20 controls, matched for age, gender, ethnic origin and oral hygiene status. Antibody titres were measured by ELISA and ...

journal_title：Journal of periodontal research

authors： Benjamin PA,Rogers PA,U S,Johnson NW,Cole MF,Curtis MA

更新日期：1997-01-01 00:00:00

abstract：:A single-blind investigation was designed to study the effects of piroxicam in preventing gingival inflammation and plaque formation in beagle dogs. Twelve 1-year-old beagles were brought to optimum oral hygiene and gingival health. Thereafter, they were fed a moist plaque-promoting diet and were divided into three gr...

journal_title：Journal of periodontal research

authors： Howell TH,Fiorellini J,Weber HP,Williams RC

更新日期：1991-05-01 00:00:00

abstract：:It is well recognized that human periodontal ligament cells (PDL cells) may represent local immune cells of the periodontal tissues. However, it is unclear whether they represent "true" immune cells, since they can produce pro-inflammatory cytokines not only after stimulation with bacterial lipopolysaccharides but als...

journal_title：Journal of periodontal research

authors： Nilsson BO

更新日期：2020-12-10 00:00:00

abstract：:The matrix metalloproteinases (MMPs) collagenase, gelatinase A (72 kDa gelatinase), stromelysin, and their specific inhibitor TIMP-1 (tissue inhibitor of metalloproteinases), were immunolocalized using specific polyclonal antisera in gingival tissues from 21 patients with chronic inflammatory periodontal disease. Mono...

journal_title：Journal of periodontal research

authors： Meikle MC,Hembry RM,Holley J,Horton C,McFarlane CG,Reynolds JJ

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:Developmental endothelial locus-1 (Del-1), lymphocyte function-associated antigen-1 (LFA-1), and interleukin 17 (IL-17) play critical roles in transendothelial migration of neutrophils in periodontal diseases. The aim of this study was to evaluate salivary Del-1, IL-17, and LFA-1 protein levels...

journal_title：Journal of periodontal research

authors： Inönü E,Kayis SA,Eskan MA,Hakki SS

更新日期：2020-08-01 00:00:00

abstract：:E-selectin is a cytokine-inducible endothelial glycoprotein which participates in the binding of leukocytes to vascular endothelium. Variable levels of expression of E-selectin have been reported in gingivitis and periodontitis, and two differing concepts of its significance have emerged: either gingival blood vessels...

journal_title：Journal of periodontal research

authors： Pietrzak ER,Savage NW,Xu LJ,Walsh LJ

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:PTH plays an important role in bone remodeling, and different actions have been reported depending on its administration method. iPSCs are promising as a cell source for regeneration of periodontal tissue due to their ability of proliferation and pluripotency. However, the effects of PTH on iPSCs ...

journal_title：Journal of periodontal research

authors： Sato M,Aoki H,Nakamura T,Onodera S,Yamaguchi A,Saito A,Azuma T

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Granulation tissue remodeling and myofibroblastic differentiation are critically important events during wound healing. Tobacco smoking has a detrimental effect in gingival tissue repair. However, studies evaluating the effects of cigarette smoke on these events are lacking. MATERIAL AND METHODS:We used gin...

journal_title：Journal of periodontal research

authors： Romero A,Cáceres M,Arancibia R,Silva D,Couve E,Martínez C,Martínez J,Smith PC

更新日期：2015-06-01 00:00:00

abstract：:Quantitative assessment of osseous changes attributable to periodontal disease is made possible by digital subtraction radiography. Tissues through which x rays travel to produce dental radiographs essential to this process alter the energy spectrum of the beam such that calibration errors result when densitometry is ...

journal_title：Journal of periodontal research

authors： Webber RL,Tzukert A,Ruttimann U

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Salivary proteomics technology can be used to evaluate the disease progression of periodontitis and the systemic screening of proteomes of saliva from subjects with aggressive periodontitis has not been available. The objective of this preliminary study was to compare the proteomic profile of w...

journal_title：Journal of periodontal research

authors： Wu Y,Shu R,Luo LJ,Ge LH,Xie YF

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Endotoxin tolerance is characterized by a state of hyporesponsiveness after confrontation with endotoxins such as lipopolysaccharides (LPS) at low concentrations. The aim of this study was to investigate, whether pretreatment with Porphyromonas gingivalis leads to endotoxin tolerance induction and...

journal_title：Journal of periodontal research

authors： Blufstein A,Behm C,Nguyen PQ,Rausch-Fan X,Andrukhov O

更新日期：2018-08-01 00:00:00

abstract：:Epidermal growth factor (EGF) is a small molecular weight polypeptide which is thought to have important functions in epithelial growth and differentiation and in wound healing. EGF exerts its action on cells through binding to a cell surface receptor. Using immunohistochemistry and a monoclonal antibody (mAb) directe...

journal_title：Journal of periodontal research

authors： Nordlund L,Hormia M,Saxén L,Thesleff I

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVES:Reactive oxygen species (ROS) are implicated in the destruction of the periodontium during inflammatory periodontal diseases. The imbalance in oxidant/antioxidant activity may be a key factor in the damaging effects of ROS. This study aimed to determine the lipid peroxidation levels in gingival crevicular fl...

journal_title：Journal of periodontal research

authors： Tsai CC,Chen HS,Chen SL,Ho YP,Ho KY,Wu YM,Hung CC

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:Smoking causes pathological changes in all tissues, including gingiva and alveolar bone. The aim of present study was to evaluate apoptotic tissue alterations and tissue destruction in smoker and non-smoker periodontitis patients and healthy individuals. METHODS:Gingival biopsy samples from 15 systemically a...

journal_title：Journal of periodontal research

authors： Karatas O,Balci Yuce H,Tulu F,Taskan MM,Gevrek F,Toker H

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:To evaluate the association between periodontal disease, tooth loss and coronary heart disease (CHD). There is still controversy about the relationship between periodontal disease and tooth loss with vessel obstruction assessed using coronary angiography. MATERIAL AND METHODS:This cross-sectio...

journal_title：Journal of periodontal research

authors： Zanella SM,Pereira SS,Barbisan JN,Vieira L,Saba-Chujfi E,Haas AN,Rösing CK

更新日期：2016-04-01 00:00:00

abstract：:The goal of a single step therapy has been an important consideration in the development of guided tissue regeneration devices. It would spare the patient from the need for repeated surgery and eliminate many problems associated with a non-resorbable barrier. Animal studies of a collagen membrane extracted from porcin...

journal_title：Journal of periodontal research

authors： Lu HK,Lee SY,Lin FP

更新日期：1998-07-01 00:00:00

abstract：:Human gingival tissues from periodontitis patients were found to contain from 126 fg/mg to 2161 fg/mg interleukin-1 beta as determined by a sensitive enzyme linked immunoassay. No IL-1 beta could be found in normal gingival tissue. This finding may have important consequences relevant to connective tissue destruction ...

journal_title：Journal of periodontal research

authors： Hönig J,Rordorf-Adam C,Siegmund C,Wiedemann W,Erard F

更新日期：1989-11-01 00:00:00

abstract：:Polymorphonuclear neutrophils (PMNs) are essential in host defense against periodontopathic bacteria such as Porphyromonas gingivalis. The uptake of immunoglobulin G (IgG)-opsonized bacteria via IgG Fc receptors (Fc gamma R) on PMN constitutes a central defense mechanism in periodontium. Fc gamma RIIIb is the most abu...

journal_title：Journal of periodontal research

authors： Kobayashi T,van der Pol WL,van de Winkel JG,Hara K,Sugita N,Westerdaal NA,Yoshie H,Horigome T

更新日期：2000-04-01 00:00:00

abstract：:Bursts of periodontal destruction are modelled as percolation-driven phase shift events. Percolation theory, though widely used to study the flow of liquids through porous nonliving materials (e.g., soils and rocks), can be applied to bacterial or toxicological penetration of living tissue in only an approximate sense...

journal_title：Journal of periodontal research

authors： Cohen ME

更新日期：1993-11-01 00:00:00

abstract：:Ketoprofen creams were evaluated for the treatment of periodontal disease in a placebo-controlled, double-blind study in the rhesus monkeys, Macaca mulatta. Two formulations containing ketoprofen (1%), with or without vitamin E, were evaluated against appropriate controls (8 monkeys per group). Two weeks prior to trea...

journal_title：Journal of periodontal research

authors： Li KL,Vogel R,Jeffcoat MK,Alfano MC,Smith MA,Collins JG,Offenbacher S

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Osteonecrosis of the jaw (ONJ) is associated with bisphosphonate (BP) therapy. BPs alter osteoblast production of mediators of osteoclastogenesis, including interleukin (IL)-6, RANKL and osteoprotegerin (OPG), a RANKL antagonist. This can inhibit bone turnover and lead to necrosis. There is lit...

journal_title：Journal of periodontal research

authors： Tipton DA,Seshul BA,Dabbous MKh

更新日期：2011-02-01 00:00:00

abstract：:The aim of this study was to compare the percentage of vital microorganisms (= microbial vitality) of saliva with that of supragingival plaque both collected at various times during the early phases of de novo plaque formation. Between intervals of optimal oral hygiene, 14 healthy participants refrained from all oral ...

journal_title：Journal of periodontal research

authors： Weiger R,von Ohle C,Decker E,Axmann-Krcmar D,Netuschil L

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVES:Previous studies have suggested an association between chronic infection and cardiovascular disease, and combined infection/inflammation is frequently related with hypertriglyceridemia, which may be a risk factor of cardiovascular disease. In fact, experimental transient or intermittent administration of lip...

journal_title：Journal of periodontal research

authors： Uchiumi D,Kobayashi M,Tachikawa T,Hasegawa K

更新日期：2004-04-01 00:00:00

abstract：:Using an agar-skim milk gel method, over 300 oral bacterial isolates were tested for their ability to produce trypsin or chymotrypsin inhibitor. Eleven bacterial strains, including seven isolates identified as Bacteroides intermedius, were found to inhibit both proteolytic activities. The inhibitory factors of the 11 ...

journal_title：Journal of periodontal research

authors： Grenier D

更新日期：1991-09-01 00:00:00

abstract：:Interleukin-1 (IL-1) molecules, IL-1 alpha and IL-1 beta are cytokines involved in the acute-phase response against infection and in the pathogenesis of periodontal destruction. Administration of exogenous IL-1 receptor antagonist (IL-1ra) is effective in reducing the inflammatory reactions mediated by IL-1. However, ...

journal_title：Journal of periodontal research

authors： Ishihara Y,Nishihara T,Kuroyanagi T,Shirozu N,Yamagishi E,Ohguchi M,Koide M,Ueda N,Amano K,Noguchi T

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:It has been suggested that aggressive periodontitis has a genetic basis. Monocyte chemoattractant protein 1 (MCP-1) plays a critical role in the recruitment of monocytes and the development of periodontitis. The -2518MCP-1(A/G) polymorphism has been implicated as a risk or susceptibility factor...

journal_title：Journal of periodontal research

authors： Zhu XL,Meng HX,Zhang L,Xu L,Chen ZB,Shi D,Feng XH,Zhang X

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Postranslational modification of proteins can lead to the production of autoantibodies and loss of immune tolerance. This process has been hypothesised to be a critical factor in the pathogenesis of rheumatoid arthritis. The objective of this study was to demonstrate that inflamed human gingiva...

journal_title：Journal of periodontal research

authors： Bright R,Thiele GM,Manavis J,Mikuls TR,Payne JB,Bartold PM

更新日期：2018-02-01 00:00:00