当前位置： SCI文献检索 > JOURNAL OF PERIODONTAL RESEARCH期刊下所有文献 > Periodontal disease, tooth loss and coronary heart disease assessed by coronary angiography: a cross-sectional observational study.

Periodontal disease, tooth loss and coronary heart disease assessed by coronary angiography: a cross-sectional observational study.

Abstract：

OBJECTIVE AND BACKGROUND:To evaluate the association between periodontal disease, tooth loss and coronary heart disease (CHD). There is still controversy about the relationship between periodontal disease and tooth loss with vessel obstruction assessed using coronary angiography. MATERIAL AND METHODS:This cross-sectional study included 195 patients that underwent coronary angiography and presented with at least six teeth. Patients were classified into three categories of coronary obstruction severity: absence; one or more vessels with ≤ 50% obstruction; and one or more vessels with ≥ 50% obstruction. The extent of coronary obstruction was dichotomized into 0 and ≥ 1 affected vessels. A periodontist blinded to patient CHD status conducted a full mouth examination to determine mean clinical attachment loss, mean periodontal probing depth and tooth loss. Multiple logistic regression models were applied adjusting for age, gender, hypertension, smoking, body mass index, low-density lipoprotein cholesterol and C-reactive protein. RESULTS:Most patients were males (62.1%) older than 60 years (50.8%), and 61% of them had CHD. Mean periodontal probing depth, clinical attachment loss and tooth loss were 2.64 ± 0.72 mm, 4.40 ± 1.31 mm and 12.50 ± 6.98 teeth respectively. In the multivariable models, tooth loss was significantly associated with a higher chance of having at least one obstructed vessel (odds ratio = 1.04; 95% confidence interval 1.01-1.09) and with vessel obstruction ≥ 50% (odds ratio = 1.06; 95% confidence interval 1.01-1.11). No significant associations were found between periodontal variables and vessel obstruction. CONCLUSION:Tooth loss was found to be a risk indicator for CHD.

journal_name

J Periodontal Res

journal_title

Journal of periodontal research

authors

Zanella SM,Pereira SS,Barbisan JN,Vieira L,Saba-Chujfi E,Haas AN,Rösing CK

doi

10.1111/jre.12301

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

221-7

issue

2

eissn

0022-3484

issn

1600-0765

journal_volume

51

pub_type

杂志文章

相关文献

JOURNAL OF PERIODONTAL RESEARCH文献大全
  • Immunolocalization of matrix metalloproteinases and TIMP-1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients.

    abstract：:The matrix metalloproteinases (MMPs) collagenase, gelatinase A (72 kDa gelatinase), stromelysin, and their specific inhibitor TIMP-1 (tissue inhibitor of metalloproteinases), were immunolocalized using specific polyclonal antisera in gingival tissues from 21 patients with chronic inflammatory periodontal disease. Mono...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1994.tb01100.x

    authors： Meikle MC,Hembry RM,Holley J,Horton C,McFarlane CG,Reynolds JJ

    更新日期：1994-03-01 00:00:00

  • Correlation between periodontal disease, inflammatory alterations and pre-eclampsia.

    abstract：BACKGROUND AND OBJECTIVE:Several studies have hypothesized that periodontal disease may increase the risk of pre-eclampsia. The correlation between the two diseases would probably be based on hypertension-related cytokine release in the local periodontal environment. The aim of this study was to evaluate the associatio...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2011.01368.x

    authors： Politano GT,Passini R,Nomura ML,Velloso L,Morari J,Couto E

    更新日期：2011-08-01 00:00:00

  • Antibody reactive with Porphyromonas gingivalis hemagglutinin in chronic and generalized aggressive periodontitis.

    abstract：BACKGROUND:Porphyromonas gingivalis, a black-pigmented, gram-negative anaerobe, is found in periodontitis lesions and its presence in subgingival plaque significantly increases the risk for periodontitis. We have previously shown that patients with aggressive forms of periodontitis that are seropositive for P. gingival...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2004.00735.x

    authors： Califano JV,Chou D,Lewis JP,Rogers JD,Best AM,Schenkein HA

    更新日期：2004-08-01 00:00:00

  • Gingival crevicular interleukin-1 and interleukin-1 receptor antagonist levels in periodontally healthy and diseased sites.

    abstract：:Interleukin-1 (IL-1) molecules, IL-1 alpha and IL-1 beta are cytokines involved in the acute-phase response against infection and in the pathogenesis of periodontal destruction. Administration of exogenous IL-1 receptor antagonist (IL-1ra) is effective in reducing the inflammatory reactions mediated by IL-1. However, ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1997.tb00568.x

    authors： Ishihara Y,Nishihara T,Kuroyanagi T,Shirozu N,Yamagishi E,Ohguchi M,Koide M,Ueda N,Amano K,Noguchi T

    更新日期：1997-08-01 00:00:00

  • Immunoglobulin G profiles in different forms of periodontitis.

    abstract：BACKGROUND:Races and Gm(23) allotypes can modify the serum levels of IgG subclasses. The average serum levels of IgG subclasses of African-Americans have been reported to be higher than those of Caucasians in both healthy young adults and patients with aggressive periodontitis; Gm(23)-positive subjects generally had hi...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0765.2003.00675.x

    authors： Chung HY,Lu HC,Chen WL,Lu CT,Yang YH,Tsai CC

    更新日期：2003-10-01 00:00:00

  • Decreased expression of E-cadherin by Porphyromonas gingivalis-lipopolysaccharide attenuates epithelial barrier function.

    abstract：BACKGROUND AND OBJECTIVE:The gingival epithelium is a first line of defense against bacterial challenge. E-cadherin (E-cad) plays an important role in cell-cell adhesion as a barrier in the epithelium. Recently, a decrease in the expression of E-cad has been observed in inflamed gingival tissue. The aims of this study ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12367

    authors： Abe-Yutori M,Chikazawa T,Shibasaki K,Murakami S

    更新日期：2017-02-01 00:00:00

  • Relation between periodontal disease and arterial stiffness.

    abstract：BACKGROUND AND OBJECTIVE:Periodontal disease has been described as playing a role in the atherosclerosis process, and its relation with intimal thickness and vascular endothelial function (EF) has been investigated. The present study sought to determine whether there are differences in parameters of arterial stiffness ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12376

    authors： Nicolosi LN,Lewin PG,Rudzinski JJ,Pompeo M,Guanca F,Rodríguez P,Gelpi RJ,Rubio MC

    更新日期：2017-02-01 00:00:00

  • Methylglyoxal and methylglyoxal-modified collagen as inducers of cellular injury in gingival connective tissue cells.

    abstract：BACKGROUND AND OBJECTIVES:Methylglyoxal is a toxic product derived from glucose metabolism that plays a role in inflammation, diabetes and aging. In addition, the periodontal pathogen Tannerella forsythensis may also generate this compound. However, the effects of methylglyoxal on gingival cells are still poorly unders...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12365

    authors： Retamal IN,Hernández R,González-Rivas C,Cáceres M,Arancibia R,Romero A,Martínez C,Tobar N,Martínez J,Smith PC

    更新日期：2016-12-01 00:00:00

  • Defense mechanism of heme oxygenase-1 against cytotoxic and receptor activator of nuclear factor-kappaB ligand inducing effects of hydrogen peroxide in human periodontal ligament cells.

    abstract：BACKGROUND AND OBJECTIVE:Although induction of heme oxygenase-1 by H2O2 has been reported, the protective role of heme oxygenase-1 against the cytotoxic and osteoclastogenic effects of H2O2 have not been elucidated in human periodontal ligament cells. The aim of this work was to investigate the defense mechanism of hem...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2006.00953.x

    authors： Pi SH,Kim SC,Kim HT,Lee HJ,Lee SK,Kim EC

    更新日期：2007-08-01 00:00:00

  • Effect of bisphosphonates on human gingival fibroblast production of mediators of osteoclastogenesis: RANKL, osteoprotegerin and interleukin-6.

    abstract：BACKGROUND AND OBJECTIVE:Osteonecrosis of the jaw (ONJ) is associated with bisphosphonate (BP) therapy. BPs alter osteoblast production of mediators of osteoclastogenesis, including interleukin (IL)-6, RANKL and osteoprotegerin (OPG), a RANKL antagonist. This can inhibit bone turnover and lead to necrosis. There is lit...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2010.01306.x

    authors： Tipton DA,Seshul BA,Dabbous MKh

    更新日期：2011-02-01 00:00:00

  • Long-term exposure of human gingival fibroblasts to cigarette smoke condensate reduces cell growth by modulating Bax, caspase-3 and p53 expression.

    abstract：BACKGROUND AND OBJECTIVE:Smoking cigarettes increases the risk of oral tissue damage leading to periodontal disease. Gingival fibroblasts, the predominant cell type inhabiting gingival connective tissue, play a critical role in remodeling and maintaining gingival structure. The objective of this study was to investigat...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12223

    authors： Alamri A,Semlali A,Jacques É,Alanazi M,Zakrzewski A,Chmielewski W,Rouabhia M

    更新日期：2015-08-01 00:00:00

  • Analysis of interleukin-1beta-modulated mRNA gene transcription in human gingival keratinocytes by epithelia-specific cDNA microarrays.

    abstract：BACKGROUND/OBJECTIVES:Proinflammatory cytokines such as interleukin-1beta are known to be synthesized in oral gingivitis and periodontitis and lead to the activation of the transcription factor nuclear factor-kappaB (NF-kappaB). Although numerous effects of interleukin-1beta on mesenchymal cells are known, e.g. up-regu...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2006.00884.x

    authors： Steinberg T,Dannewitz B,Tomakidi P,Hoheisel JD,Müssig E,Kohl A,Nees M

    更新日期：2006-10-01 00:00:00

  • Povidone-iodine as a periodontal pocket disinfectant.

    abstract：OBJECTIVES AND BACKGROUND:Povidone-iodine [polyvinylpyrrolidone-iodine complex (PVP-iodine)] might constitute a valuable adjunct to current periodontal therapy because of its broad-spectrum antimicrobial activity, low potential for developing resistance and adverse reactions, wide availability, ease of use, and low fin...

    journal_title：Journal of periodontal research

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1034/j.1600-0765.2003.02016.x

    authors： Hoang T,Jorgensen MG,Keim RG,Pattison AM,Slots J

    更新日期：2003-06-01 00:00:00

  • Proteome data set of human gingival crevicular fluid from healthy periodontium sites by multidimensional protein separation and mass spectrometry.

    abstract：BACKGROUND AND OBJECTIVE:Gingival crevicular fluid has been of major interest for many decades as a valuable body fluid that may serve as a source of biomarkers for both periodontal and systemic diseases. Owing to its very small sample size, submicroliter volumes, identification of its protein composition by classical ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2011.01429.x

    authors： Carneiro LG,Venuleo C,Oppenheim FG,Salih E

    更新日期：2012-04-01 00:00:00

  • Ultrastructure of cementogenesis as affected by growth hormone in the molar periodontium of the hypophysectomized rat.

    abstract：:To document the effect of hypophysectomy and growth hormone replacement on the ultrastructure of cementogenesis in the developing rat third molar, 12 female Wistar rats were randomly allocated to normal control, hypophysectomized or hypophysectomized plus human growth hormone (for 10 days) treatment groups. The result...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1994.tb01221.x

    authors： Clayden AM,Young WG,Zhang CZ,Harbrow D,Romaniuk K,Waters MJ

    更新日期：1994-07-01 00:00:00

  • Repeated exposure to whole cigarette smoke promotes primary human gingival epithelial cell growth and modulates keratin expression.

    abstract：BACKGROUND AND OBJECTIVE:The gingiva is the first oral tissue directly exposed to cigarette smoke (CS). Exposure to CS compromises the structure and function of gingival tissue. Damaging or altering the gingival epithelium leads to a compromised protective barrier of the periodontium, resulting in several diseases. The...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12343

    authors： Alharbi IA,Rouabhia M

    更新日期：2016-10-01 00:00:00

  • Lipopolysaccharide-regulated production of bone sialoprotein and interleukin-8 in human periodontal ligament fibroblasts: the role of toll-like receptors 2 and 4 and the MAPK pathway.

    abstract：BACKGROUND AND OBJECTIVE:Lipopolysaccharide (LPS) on the cell wall of periodontal pathogens is a major mediator of the inflammatory response and can enhance alveolar bone resorption in periodontitis. Bone sialoprotein is an early marker of osteoblast differentiation. The proinflammatory cytokine, interleukin-8 (IL-8), ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12193

    authors： Zhang Y,Li X

    更新日期：2015-04-01 00:00:00

  • Single nucleotide polymorphisms in long noncoding RNA, ANRIL, are not associated with severe periodontitis but with adverse cardiovascular events among patients with cardiovascular disease.

    abstract：BACKGROUND AND OBJECTIVE:Biological plausibility of an association between severe periodontitis and cardiovascular disease (CVD) has been proven. Genetic characteristics play an important role in both complex inflammatory diseases. Polymorphisms (single nucleotide polymorphisms [SNPs]) in the long noncoding RNA, antise...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12555

    authors： Schulz S,Seitter L,Werdan K,Hofmann B,Schaller HG,Schlitt A,Reichert S

    更新日期：2018-10-01 00:00:00

  • Bradykinin-2 receptor-mediated release of 3H-arachidonic acid and formation of prostaglandin E2 in human gingival fibroblasts.

    abstract：:Bradykinin stimulated production of prostaglandin E2 (PGE2) and the release of 3H-arachidonic acid by gingival fibroblasts in a time- and dose-dependent manner. The effect on PGE2 biosynthesis was seen already after 15 seconds and was maximal after 5 minutes. Several structurally unrelated inhibitors of arachidonic ac...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1990.tb00928.x

    authors： Modéer T,Ljunggren O,Lerner UH

    更新日期：1990-11-01 00:00:00

  • Bursts of periodontal destruction and remission, percolation phase shifts, and chaos.

    abstract：:Bursts of periodontal destruction are modelled as percolation-driven phase shift events. Percolation theory, though widely used to study the flow of liquids through porous nonliving materials (e.g., soils and rocks), can be applied to bacterial or toxicological penetration of living tissue in only an approximate sense...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：

    authors： Cohen ME

    更新日期：1993-11-01 00:00:00

  • Isolation of alkaline phosphatase-positive gingival fibroblasts from patients with chronic inflammatory periodontal disease.

    abstract：:We have reported recently that increased expression of membrane alkaline phosphatase (ALP) activity is a phenotypical characteristic of gingival fibroblasts located in chronic inflammatory periodontal lesions. To understand the cellular properties of these cells, we isolated ALP-positive gingival fibroblasts from pati...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1996.tb00495.x

    authors： Abe T,Hara Y,Abe Y,Aida Y,Maeda K

    更新日期：1996-05-01 00:00:00

  • Topical application of Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces cell cycle arrest in the rat gingival epithelium in vivo.

    abstract：BACKGROUND:Aggregatibacter actinomycetemcomitans is one of the etiological pathogens implicated in the onset of periodontal disease. This pathogen produces cytolethal distending toxin (CDT) that acts as a genotoxin to induce cell cycle arrest and cellular distension in cultured cell lines. Therefore, CDT is a possible ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2011.01348.x

    authors： Ohara M,Miyauchi M,Tsuruda K,Takata T,Sugai M

    更新日期：2011-06-01 00:00:00

  • Vital microorganisms in early supragingival dental plaque and in stimulated human saliva.

    abstract：:The aim of this study was to compare the percentage of vital microorganisms (= microbial vitality) of saliva with that of supragingival plaque both collected at various times during the early phases of de novo plaque formation. Between intervals of optimal oral hygiene, 14 healthy participants refrained from all oral ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1997.tb00529.x

    authors： Weiger R,von Ohle C,Decker E,Axmann-Krcmar D,Netuschil L

    更新日期：1997-02-01 00:00:00

  • Histochemical localization at the electron microscopic level of sulfated glycosaminoglycans in the rat gingiva.

    abstract：:Using the high iron diamine thiocarbohydrazide silver proteinate (HID-TCH-SP) staining technique, we investigated ultrastructural localization of sulfated glycosaminoglycans (GAGs) in the rat gingiva shortly after eruption, especially those associated with internal and external basal laminae. In the apical portion of ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1989.tb02006.x

    authors： Kogaya Y,Haruna S,Vojinovic J,Iwayama Y,Akisaka T

    更新日期：1989-05-01 00:00:00

  • Gingival crevicular fluid and plasma levels of neuropeptide Substance-P in periodontal health, disease and after nonsurgical therapy.

    abstract：BACKGROUND AND OBJECTIVE:The level of Substance-P in gingival crevicular fluid has been found to correlate with clinical measures of periodontal disease. The present study was designed to assess the relationship between clinical parameters and levels of Substance-P in the gingival crevicular fluid from inflamed gingiva...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2008.01138.x

    authors： Pradeep AR,Raj S,Aruna G,Chowdhry S

    更新日期：2009-04-01 00:00:00

  • Interleukin-1 alpha produced in human gingival fibroblasts induces several activities related to the progression of periodontitis by direct contact.

    abstract：:Previous observations suggest that interleukin-1 (IL-1) may play an important role in the progression of periodontitis. In the present study, we investigated whether a cell-associated IL-1 alpha (CAIL-1 alpha) produced in human gingival fibroblasts (HGF) induces biological activities related to the progression of peri...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1996.tb00503.x

    authors： Okamatsu Y,Kobayashi M,Nishihara T,Hasegawa K

    更新日期：1996-07-01 00:00:00

  • Effects of periodontal non-surgical therapy plus azithromycin on glycemic control in patients with diabetes: a randomized clinical trial.

    abstract：BACKGROUND AND OBJECTIVE:Periodontitis may alter the systemic condition in patients with diabetes and hence interfere with glycemic control. The objective of this study was to determine the quantifiable changes in glycated hemoglobin (HbA1C) after periodontal non-surgical therapy plus azithromycin in a mixed population...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/jre.12058

    authors： Botero JE,Yepes FL,Ochoa SP,Hincapie JP,Roldan N,Ospina CA,Castrillon CA,Becerra MA

    更新日期：2013-12-01 00:00:00

  • Expression of transforming growth factor-beta receptors types II and III within various cells in the rat periodontium.

    abstract：:This study reports the immunohistochemical localization of TGF-beta receptor type II (T beta R-II) and type III (T beta R-III) in cells of the forming periodontal ligament (PDL) in rat first molar roots. Mandibular periodontium was obtained from 3, 6 and 12-wk-old rats. This represented tissue from the initial, pre-ma...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1999.tb02230.x

    authors： Gao J,Symons AL,Bartold PM

    更新日期：1999-02-01 00:00:00

  • Alpha-terpineol complexed with beta-cyclodextrin reduces damages caused by periodontitis in rats.

    abstract：BACKGROUND AND OBJECTIVE:This study aimed to assess the effectiveness of the treatment with alpha-terpineol (αTPN) complexed with beta-cyclodextrin (βCD) on oral, blood, and hepatic parameters in ligature-induced periodontitis. MATERIAL AND METHODS:Forty female rats were distributed among the following groups: control...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12780

    authors： Vasconcelos ACCG,Vasconcelos DFP,da Silva FRP,França LFC,Alves EHP,Di Lenardo D,Pessoa LDS,Nascimento HMS,Carvalho ADS,Sousa FBM,Barbosa ALDR,Medeiros JR,Novaes PD,Mariano FS,Lima BDS,Araujo AAS,Júnior LJQ,de Oliveira A

    更新日期：2020-12-01 00:00:00

  • Parotid secretory protein is expressed and inducible in human gingival keratinocytes.

    abstract：BACKGROUND:Parotid secretory protein (PSP) is a major salivary protein that is thought to possess both antibacterial and anti-inflammatory activity. A major question is whether PSP expression can be regulated by humoral factors and bacteria. Periodontitis is an inflammatory lesion initiated by interaction between gingi...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2005.00781.x

    authors： Shiba H,Venkatesh SG,Gorr SU,Barbieri G,Kurihara H,Kinane DF

    更新日期：2005-04-01 00:00:00