Increased interleukin-1 beta (IL-1 beta) concentration in gingival tissue from periodontitis patients.

abstract：:The 3 human salivary cystatins S, SA and SN are multifunctional proteins that possess a cysteine protease inhibitory property, but their ability to act as such is very different (SN > SA > S). One form, S, also appears to possess antibacterial properties towards the bacterium Porphyromonas gingivalis, often associated...

journal_title：Journal of periodontal research

authors： Baron AC,Gansky SA,Ryder MI,Featherstone JD

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Osteonecrosis of the jaw (ONJ) is associated with bisphosphonate (BP) therapy. BPs alter osteoblast production of mediators of osteoclastogenesis, including interleukin (IL)-6, RANKL and osteoprotegerin (OPG), a RANKL antagonist. This can inhibit bone turnover and lead to necrosis. There is lit...

journal_title：Journal of periodontal research

authors： Tipton DA,Seshul BA,Dabbous MKh

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Multiple studies support the role of periodontal disease in contributing to the chronic systemic inflammatory burden in a variety of diseases, including ankylosing spondylitis (AS), in the progression which the inflammatory process plays an important role. We assume that patients with AS are mo...

journal_title：Journal of periodontal research

authors： Sezer U,Erciyas K,Pehlivan Y,Ustün K,Tarakçioğlu M,Senyurt SZ,Onat AM

更新日期：2012-06-01 00:00:00

abstract：:This study was designed to study wound strength at the dentine/connective tissue interface and at the bone/connective tissue interface following full thickness flap surgery. Flaps of uniform dimension were outlined in four young adult beagle dogs using a standardised double bladed knife and vertical incisions 10 mm ap...

journal_title：Journal of periodontal research

authors： Werfully S,Areibi G,Toner M,Bergquist J,Walker J,Renvert S,Claffey N

更新日期：2002-10-01 00:00:00

abstract：:Quantitative assessment of osseous changes attributable to periodontal disease is made possible by digital subtraction radiography. Tissues through which x rays travel to produce dental radiographs essential to this process alter the energy spectrum of the beam such that calibration errors result when densitometry is ...

journal_title：Journal of periodontal research

authors： Webber RL,Tzukert A,Ruttimann U

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to evaluate the effects of increased oxygen availability on gene expression and on collagen deposition/maturation in the periodontium following disease. MATERIAL AND METHODS:Male Wistar rats had ligatures placed around their molars to induce periodontal disease, and a...

journal_title：Journal of periodontal research

authors： Gajendrareddy PK,Junges R,Cygan G,Zhao Y,Marucha PT,Engeland CG

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cannabinoid receptor CB2, expressed in osteoblasts and osteoclasts, plays a crucial role in the regulation of bone metabolism. Since periodontal ligament (PDL) cells can differentiate into osteoblasts, this study was undertaken to investigate CB2 expression and the effect of CB2 activation on o...

journal_title：Journal of periodontal research

authors： Qian H,Zhao Y,Peng Y,Han C,Li S,Huo N,Ding Y,Duan Y,Xiong L,Sang H

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Enamel matrix proteins are involved in the development and regeneration of root cementum and in its attachment to dentin; however, the mechanisms through which this occurs have yet to be elucidated. The present study was therefore carried out to evaluate the mitogenic and proliferative response...

journal_title：Journal of periodontal research

authors： Khedmat S,Seyedabadi M,Ghahremani MH,Ostad SN

更新日期：2011-02-01 00:00:00

abstract：:Polymorphonuclear neutrophils (PMNs) are essential in host defense against periodontopathic bacteria such as Porphyromonas gingivalis. The uptake of immunoglobulin G (IgG)-opsonized bacteria via IgG Fc receptors (Fc gamma R) on PMN constitutes a central defense mechanism in periodontium. Fc gamma RIIIb is the most abu...

journal_title：Journal of periodontal research

authors： Kobayashi T,van der Pol WL,van de Winkel JG,Hara K,Sugita N,Westerdaal NA,Yoshie H,Horigome T

更新日期：2000-04-01 00:00:00

abstract：:Cyclosporine (CsA) is a selective immunosuppressant widely used in clinical therapy. Like phenytoin and nifedipine, the drug is associated with gingival overgrowth. This study considers the interaction of CsA and prostaglandin I2 (PGI2), in particular the action of the drug on gingival tissue in vitro and in vivo. The...

journal_title：Journal of periodontal research

authors： Nell A,Matejka M,Solar P,Ulm C,Sinzinger H

更新日期：1996-02-01 00:00:00

abstract：:This paper reviews the literature on prepubertal periodontitis (PP) according to the definition and the classification of PP by Page. The generalized form of PP (G-PP) defined by Page was identified as the oral manifestation of a systemic disease called leukocyte adhesion deficiency (LAD) and thus the pathogenesis is ...

journal_title：Journal of periodontal research

authors： Watanabe K

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Periodontal disease has been described as playing a role in the atherosclerosis process, and its relation with intimal thickness and vascular endothelial function (EF) has been investigated. The present study sought to determine whether there are differences in parameters of arterial stiffness ...

journal_title：Journal of periodontal research

authors： Nicolosi LN,Lewin PG,Rudzinski JJ,Pompeo M,Guanca F,Rodríguez P,Gelpi RJ,Rubio MC

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Osteogenic proteins of the transforming growth factor-beta superfamily induce periodontal tissue regeneration in animal models, including primates. To our knowledge, no studies have been performed in periodontal regeneration using the transforming growth factor-beta 3 isoform. In the present st...

journal_title：Journal of periodontal research

authors： Teare JA,Ramoshebi LN,Ripamonti U

更新日期：2008-02-01 00:00:00

abstract：:This umbrella review appraised existing systematic reviews and meta-analysis to establish the impact of periodontal disease and therapy on general and oral health-related quality of life. A systematic electronic literature search was carried out in accordance with the PRISMA guideline up to January 2020 using PubMed, ...

journal_title：Journal of periodontal research

authors： Wong LB,Yap AU,Allen PF

更新日期：2021-01-01 00:00:00

abstract：:Effects of lathyrogens such as aminoacetonitrile (AAN), beta-aminopropionitrile (BAPN) and cysteamine--known inhibitors of cross-linking of collagen--on the mechanical strength of the periodontal ligament of the rat mandibular first molar were examined by measuring the ultimate load required to extract the tooth from ...

journal_title：Journal of periodontal research

authors： Ohshima S,Nakamura G,Chiba M

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The transplantation of cell sheets of mesenchymal stem cells (MSCs) is expected to be the next generation of periodontal regenerative therapy. An adequate method of multilayering MSCs has yet to be established. When cell sheets proliferate, they usually contract and detach from culture dishes a...

journal_title：Journal of periodontal research

authors： Nakamura K,Yoshimura A,Kaneko T,Sato K,Hara Y

更新日期：2014-06-01 00:00:00

abstract：:E-selectin is a cytokine-inducible endothelial glycoprotein which participates in the binding of leukocytes to vascular endothelium. Variable levels of expression of E-selectin have been reported in gingivitis and periodontitis, and two differing concepts of its significance have emerged: either gingival blood vessels...

journal_title：Journal of periodontal research

authors： Pietrzak ER,Savage NW,Xu LJ,Walsh LJ

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVES:Reactive oxygen species (ROS) are implicated in the destruction of the periodontium during inflammatory periodontal diseases. The imbalance in oxidant/antioxidant activity may be a key factor in the damaging effects of ROS. This study aimed to determine the lipid peroxidation levels in gingival crevicular fl...

journal_title：Journal of periodontal research

authors： Tsai CC,Chen HS,Chen SL,Ho YP,Ho KY,Wu YM,Hung CC

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Alveolar bone resorption is a characteristic feature of periodontal diseases and involves removal of both the mineral and the organic constituents of the bone matrix, a process mainly carried out by multinucleated osteoclast cells. (-)-Epigallocatechin gallate, the main constituent of green tea...

journal_title：Journal of periodontal research

authors： Yun JH,Kim CS,Cho KS,Chai JK,Kim CK,Choi SH

更新日期：2007-06-01 00:00:00

abstract：:Though cementum of the tooth root is critical for periodontal structure and tooth attachment and function, this tissue was not discovered and characterized on human teeth until a full century later than enamel and dentin. Early observations from the seventeenth to the nineteenth centuries by Marcello Malpighi, Antonie...

journal_title：Journal of periodontal research

authors： Foster BL

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The level of Substance-P in gingival crevicular fluid has been found to correlate with clinical measures of periodontal disease. The present study was designed to assess the relationship between clinical parameters and levels of Substance-P in the gingival crevicular fluid from inflamed gingiva...

journal_title：Journal of periodontal research

authors： Pradeep AR,Raj S,Aruna G,Chowdhry S

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Recent epidemiological studies have shown that individuals with periodontitis have a significantly increased risk of developing coronary heart disease. In addition to conventional risk factors, chronic infection and subsequent production of systemic inflammatory markers may be associated with this increased ...

journal_title：Journal of periodontal research

authors： Yamazaki K,Honda T,Oda T,Ueki-Maruyama K,Nakajima T,Yoshie H,Seymour GJ

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The field of salivary diagnostics lacks an accepted and validated biomarker of alveolar bone remodeling. To address this, we examined levels of salivary biomolecules specifically associated with biological aspects of bone remodeling in subjects with chronic periodontitis in a case-control study...

journal_title：Journal of periodontal research

authors： Al-Sabbagh M,Alladah A,Lin Y,Kryscio RJ,Thomas MV,Ebersole JL,Miller CS

更新日期：2012-06-01 00:00:00

abstract：:The role of bacteria in the initiation of periodontitis is well-documented and the end result, destruction of the alveolar bone and periodontal connective tissue, is readily observed; but the events occurring between these two points in time remain obscure and are the focus of this paper. Bacteria induce tissue destru...

journal_title：Journal of periodontal research

authors： Page RC

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Little is known about the factors that affect the microbial composition of supragingival biofilms. This study was designed to examine the relationship between total DNA probe counts of supragingival biofilm samples, clinical parameters and supragingival biofilm composition. MATERIAL AND METHOD...

journal_title：Journal of periodontal research

authors： Haffajee AD,Teles RP,Patel MR,Song X,Veiga N,Socransky SS

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Long-term tooth retention is the ultimate goal of periodontal therapy. Aim of this study was to evaluate tooth loss (TL) during 10 years of supportive periodontal therapy (SPT) in periodontal compromised patients and to identify factors influencing TL on patient level. MATERIAL AND METHODS:Pat...

journal_title：Journal of periodontal research

authors： Petsos H,Schacher B,Ramich T,Nickles K,Dannewitz B,Arendt S,Seidel K,Eickholz P

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Tobacco use is associated with increased periodontal destruction in both cigarette smokers and smokeless tobacco users. Gingival keratinocytes are the first cells in contact with microbial and tobacco components and play a key role in the innate immune response to these agents. The objective of...

journal_title：Journal of periodontal research

authors： Johnson GK,Guthmiller JM,Joly S,Organ CC,Dawson DV

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Enamel matrix derivative (EMD) is used clinically to promote periodontal tissue regeneration, and it has been reported that EMD can induce the formation of osteoclasts in mouse marrow cultures. In the present study, we investigated the mechanisms of EMD-induced osteoclast formation using a mous...

journal_title：Journal of periodontal research

authors： Itoh N,Kasai H,Ariyoshi W,Harada E,Yokota M,Nishihara T

更新日期：2006-08-01 00:00:00

abstract：:A single-blind investigation was designed to study the effects of piroxicam in preventing gingival inflammation and plaque formation in beagle dogs. Twelve 1-year-old beagles were brought to optimum oral hygiene and gingival health. Thereafter, they were fed a moist plaque-promoting diet and were divided into three gr...

journal_title：Journal of periodontal research

authors： Howell TH,Fiorellini J,Weber HP,Williams RC

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We recently proposed a novel mechanism linking periodontitis and systemic diseases, in which orally administered Porphyromonas gingivalis affects gut microbiota composition and subsequently leads to systemic inflammation. However, the mechanism by which P. gingivalis generates systemic effects...

journal_title：Journal of periodontal research

authors： Sato K,Yokoji M,Yamada M,Nakajima T,Yamazaki K

更新日期：2018-12-01 00:00:00