Abstract:
:This study was designed to study wound strength at the dentine/connective tissue interface and at the bone/connective tissue interface following full thickness flap surgery. Flaps of uniform dimension were outlined in four young adult beagle dogs using a standardised double bladed knife and vertical incisions 10 mm apart, which extended 8 mm apical to the gingival margin. Bone was removed from half the sites (eight sites in each dog), giving 32 flaps replaced on dentine and 32 sites on bone. A tensile force was applied using a microprocessor force gauge at 1, 2, 3, 7, 10, 14, 21, and 28 days. Mean tensile strengths were markedly weaker for the dentine/flap interface. At 7 days the value for flaps to dentine was 1.82 N, in contrast to 5.08 N for flaps replaced on bone. Inflammatory cell counts tended to fall markedly at 3 days for both modalities, but were higher for the dentine/flap modality at all time points. Fibroblast density peaked at 7-14 days but did not vary with type of flap over the time points studied. The amounts of fibrin were greater for the dentine/flap interface at all time points but decreased for both flap types as time progressed. Collagen type V was localised to the basement membrane and blood vessels and tended to show more foci for flaps replaced on dentine. Procollagen levels showed little change over the healing interval for both flap/bone and flap/dentine interfaces. Type III collagen synthesis was at peak levels during the first week. These findings would support efforts to stabilise periodontal flaps at early time points, especially those on dentine.
journal_name
J Periodontal Resjournal_title
Journal of periodontal researchauthors
Werfully S,Areibi G,Toner M,Bergquist J,Walker J,Renvert S,Claffey Ndoi
10.1034/j.1600-0765.2002.01375.xsubject
Has Abstractpub_date
2002-10-01 00:00:00pages
366-74issue
5eissn
0022-3484issn
1600-0765pii
1o375journal_volume
37pub_type
杂志文章abstract::The effectiveness of an ideal antimicrobial agent depends on its ability to kill microbes with minimal toxicity to host cells. Depending on the treatment regimen, antimicrobial agents come into contact with host cells for various intervals of time. Sanguinarium (SANG), chlorhexidine (CHX) and tetracycline (TET) are 3 ...
journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.1997.tb00542.x
更新日期:1997-04-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.2007.00983.x
更新日期:2007-12-01 00:00:00
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journal_title:Journal of periodontal research
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doi:10.1111/j.1600-0765.2005.00832.x
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The expression of A Disintegrin and Metalloproteinase 8 (ADAM8) is associated with several inflammatory diseases. Elevated ADAM8 levels have been shown in gingival crevicular fluid of patients with chronic periodontitis. The objective of this study was to investigate ADAM8 expression in chroni...
journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/jre.12426
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:Chronic periodontitis is a bone destructive inflammatory disease with an adverse impact on general health and suggested underlying factors in common with osteoporosis. A few studies have examined the possible relationship between chronic periodontitis and osteoporosis; however, the results remain inconclusiv...
journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/jre.12464
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:For ethical reasons it is becoming increasingly more difficult to obtain, from clinical studies, histological data on infrabony defects treated with guided tissue regeneration (GTR) techniques. The aim of this systematic review was to find the value of extrapolating animal data on treatment of ...
journal_title:Journal of periodontal research
pub_type: 杂志文章,meta分析,评审
doi:10.1111/jre.12130
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Dental rubber dams (RDs) were used as barrier membranes in guided tissue regeneration for the treatment of periodontal intraosseous defects with acceptable clinical results. The aim of the present study was to investigate the effects of autoclave sterilization on properties of RD as related to ...
journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1034/j.1600-0765.2003.00693.x
更新日期:2003-10-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.2007.00987.x
更新日期:2008-02-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.2005.00818.x
更新日期:2005-10-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
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更新日期:1993-01-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.2010.01335.x
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Periodontitis is an increasingly prevalent complication of diabetes mellitus (known as diabetes mellitus-associated periodontitis), and 25-hydroxyvitamin D3 (25VD3 ) was recently found to be a critical regulator of innate immunity in this disease, but the underlying mechanisms remain poorly und...
journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/jre.12535
更新日期:2018-06-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.2009.01206.x
更新日期:2010-02-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/jre.12216
更新日期:2015-06-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1034/j.1600-0765.2003.00367.x
更新日期:2003-04-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/jre.12343
更新日期:2016-10-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.2008.01176.x
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:After tooth formation is complete, it is suggested that continuity exists between the epithelial cell rests of Malassez (ERM), reduced enamel epithelium (REE) and subsequently the junctional epithelium. However, the junctional epithelium was reported to differ from REE and ERM. The developmenta...
journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/jre.12272
更新日期:2015-12-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.2011.01368.x
更新日期:2011-08-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1034/j.1600-0765.2002.01618.x
更新日期:2002-08-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.2007.01063.x
更新日期:2008-08-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.1991.tb02071.x
更新日期:1991-07-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/jre.12114
更新日期:2014-06-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章,评审
doi:10.1111/jre.12436
更新日期:2017-08-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 临床试验,杂志文章
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更新日期:2013-06-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.1995.tb01289.x
更新日期:1995-09-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
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更新日期:2017-04-01 00:00:00
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journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1034/j.1600-0765.2003.02002.x
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Regulation of epithelial cell behavior associated with periodontitis is not well elucidated but many responses will ultimately be regulated by growth factor receptors. Using a rat experimental periodontitis model, protein and gene expression of select growth factor receptors in junctional and p...
journal_title:Journal of periodontal research
pub_type: 杂志文章
doi:10.1111/j.1600-0765.2006.00881.x
更新日期:2006-08-01 00:00:00