Periodontal disease and quality of life: Umbrella review of systematic reviews.

Abstract:

:This umbrella review appraised existing systematic reviews and meta-analysis to establish the impact of periodontal disease and therapy on general and oral health-related quality of life. A systematic electronic literature search was carried out in accordance with the PRISMA guideline up to January 2020 using PubMed, LIVIVO, EMBASE and OpenGrey (PROSPERO CRD 42020163831). Hand searching was performed through the reference lists of periodontal textbooks and related journals. All English language-based systematic reviews and meta-analysis that assessed the impact of periodontal disease and treatment interventions on general and oral health-related quality of life were included. Overall, eight articles met the inclusion criteria and their methodological quality was assessed using the AMSTAR2 criteria. Two systematic reviews showed a significant impact of oral conditions on general health-related quality of life, although the specific impact of periodontal disease remains inconclusive. Three systematic reviews established a negative impact of periodontal disease on oral health-related quality of life. Another three systematic reviews concluded that periodontal treatment can improve oral health-related quality of life. Oral conditions, like periodontal disease, can impact the general health-related quality of life. Periodontal disease is negatively correlated with oral health-related quality of life, although treatment interventions can improve self-reported quality of life. In view of the heterogeneity of generic instruments currently utilized to assess the self-reported quality of life of periodontal patients, the development of a general and oral health-related quality of life instrument specific for periodontal disease is strongly recommended.

journal_name

J Periodontal Res

authors

Wong LB,Yap AU,Allen PF

doi

10.1111/jre.12805

subject

Has Abstract

pub_date

2021-01-01 00:00:00

pages

1-17

issue

1

eissn

0022-3484

issn

1600-0765

journal_volume

56

pub_type

杂志文章,meta分析,评审
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    authors: Chen SC,Marino V,Gronthos S,Bartold PM

    更新日期:2006-12-01 00:00:00

  • Implant osseointegration in irradiated bone: an experimental study.

    abstract:BACKGROUND AND OBJECTIVES:The aim of this study was to evaluate the effect of radiotherapy on the osseointegration of dental implants in the tibia and the action of platelet-rich plasma (PRP) as an adjuvant therapy. MATERIAL AND METHODS:A total of 18 rabbits received two implants in each tibial epiphysis, totalizing 7...

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    doi:10.1111/jre.12416

    authors: Ocaña RP,Rabelo GD,Sassi LM,Rodrigues VP,Alves FA

    更新日期:2017-06-01 00:00:00

  • Gingival crevicular interleukin-1 and interleukin-1 receptor antagonist levels in periodontally healthy and diseased sites.

    abstract::Interleukin-1 (IL-1) molecules, IL-1 alpha and IL-1 beta are cytokines involved in the acute-phase response against infection and in the pathogenesis of periodontal destruction. Administration of exogenous IL-1 receptor antagonist (IL-1ra) is effective in reducing the inflammatory reactions mediated by IL-1. However, ...

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    doi:10.1111/j.1600-0765.1997.tb00568.x

    authors: Ishihara Y,Nishihara T,Kuroyanagi T,Shirozu N,Yamagishi E,Ohguchi M,Koide M,Ueda N,Amano K,Noguchi T

    更新日期:1997-08-01 00:00:00

  • Isolation of alkaline phosphatase-positive gingival fibroblasts from patients with chronic inflammatory periodontal disease.

    abstract::We have reported recently that increased expression of membrane alkaline phosphatase (ALP) activity is a phenotypical characteristic of gingival fibroblasts located in chronic inflammatory periodontal lesions. To understand the cellular properties of these cells, we isolated ALP-positive gingival fibroblasts from pati...

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    doi:10.1111/j.1600-0765.1996.tb00495.x

    authors: Abe T,Hara Y,Abe Y,Aida Y,Maeda K

    更新日期:1996-05-01 00:00:00

  • Effects of intermittent treatment with parathyroid hormone (PTH) on osteoblastic differentiation and mineralization of mouse induced pluripotent stem cells in a 3D culture model.

    abstract:BACKGROUND/OBJECTIVES:PTH plays an important role in bone remodeling, and different actions have been reported depending on its administration method. iPSCs are promising as a cell source for regeneration of periodontal tissue due to their ability of proliferation and pluripotency. However, the effects of PTH on iPSCs ...

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    doi:10.1111/jre.12762

    authors: Sato M,Aoki H,Nakamura T,Onodera S,Yamaguchi A,Saito A,Azuma T

    更新日期:2020-10-01 00:00:00

  • Retrospectively analysed tooth loss in periodontally compromised patients: Long-term results 10 years after active periodontal therapy-Patient-related outcomes.

    abstract:BACKGROUND AND OBJECTIVE:Long-term tooth retention is the ultimate goal of periodontal therapy. Aim of this study was to evaluate tooth loss (TL) during 10 years of supportive periodontal therapy (SPT) in periodontal compromised patients and to identify factors influencing TL on patient level. MATERIAL AND METHODS:Pat...

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    doi:10.1111/jre.12786

    authors: Petsos H,Schacher B,Ramich T,Nickles K,Dannewitz B,Arendt S,Seidel K,Eickholz P

    更新日期:2020-12-01 00:00:00

  • Clinical application of autologous fibroblast cell culture in gingival recession treatment.

    abstract:BACKGROUND AND OBJECTIVE:Gingival recession is defined as soft and hard tissue displacement resulting in root surface exposure. The optimal outcome of gingival recession treatment is complete, predictable and long-lasting root coverage with a significant level of tissue regeneration. Tissue engineering, which applies a...

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    pub_type: 杂志文章,随机对照试验

    doi:10.1111/jre.12215

    authors: Milinkovic I,Aleksic Z,Jankovic S,Popovic O,Bajic M,Cakic S,Lekovic V

    更新日期:2015-06-01 00:00:00

  • (-)-Epigallocatechin gallate induces apoptosis, via caspase activation, in osteoclasts differentiated from RAW 264.7 cells.

    abstract:BACKGROUND AND OBJECTIVE:Alveolar bone resorption is a characteristic feature of periodontal diseases and involves removal of both the mineral and the organic constituents of the bone matrix, a process mainly carried out by multinucleated osteoclast cells. (-)-Epigallocatechin gallate, the main constituent of green tea...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.2006.00935.x

    authors: Yun JH,Kim CS,Cho KS,Chai JK,Kim CK,Choi SH

    更新日期:2007-06-01 00:00:00

  • Interleukin-1 genotypes and the association between periodontitis and cardiovascular disease.

    abstract::An epidemiological association between periodontitis and cardiovascular disease has been reported in multiple studies. Various mechanisms have been proposed as potential explanations for this association, including a common factor that predisposes certain individuals to a hyper-responsive inflammatory response. Variat...

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    doi:10.1111/j.1600-0765.1999.tb02265.x

    authors: Kornman KS,Pankow J,Offenbacher S,Beck J,di Giovine F,Duff GW

    更新日期:1999-10-01 00:00:00

  • Human beta defensin-1 and -2 expression in the gingiva of patients with specific periodontal diseases.

    abstract:BACKGROUND AND OBJECTIVE:beta defensin antimicrobial peptides are important in epithelial innate immunity, and their differential expression is associated with periodontal diseases. The aims of this study were to determine the mRNA expression of human beta defensin-1 and -2 in the gingival tissue of patients with gingi...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.2006.00964.x

    authors: Vardar-Sengul S,Demirci T,Sen BH,Erkizan V,Kurulgan E,Baylas H

    更新日期:2007-10-01 00:00:00

  • Cystatin A in gingival crevicular fluid of periodontal patients.

    abstract::Cystatins are physiological inhibitors of cysteine proteinases which are widely distributed in human tissues and fluids. In the present study we analysed both the cystatin activity and the different cystatin isoforms in gingival crevicular fluid and saliva samples of nine periodontitis patients. All crevicular fluid s...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.1997.tb00935.x

    authors: Blankenvoorde MF,Henskens YM,van der Weijden GA,van den Keijbus PA,Veerman EC,Nieuw Amerongen AV

    更新日期:1997-10-01 00:00:00

  • Experimental periodontitis induced by Porphyromonas gingivalis does not alter the onset or severity of diabetes in mice.

    abstract:BACKGROUND AND OBJECTIVE:Diabetes mellitus is believed to increase the risk and severity of periodontitis. However, less evidence is available on the converse effects of periodontitis on diabetes. The objective of the study was to investigate to what degree experimental periodontitis induced by Porphyromonas gingivalis...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1111/jre.12041

    authors: Li H,Yang H,Ding Y,Aprecio R,Zhang W,Wang Q,Li Y

    更新日期:2013-10-01 00:00:00

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    abstract::Neuropeptides, including substance P (SP) may play a role in neurogenic inflammation. Although SP-immunoreactive (SP-IR) axons are known to be present within the oral mucosa (OM) and salivary glands, the functional significance of SP in oral mucosa and sublingual salivary gland (SLG) is not fully understood. The prese...

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    authors: Györfi A,Fazekas A,Irmes F,Rosivall L

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  • Co-purified gelatinases alter the stability and biological activities of human plasma fibronectin preparations.

    abstract:BACKGROUND AND OBJECTIVE:Fibronectin (FN) is an important cell adhesion molecule that is used widely to characterize cell behavior. Preparations of FN purified from human plasma by gelatin-Sepharose affinity chromatography typically also contain gelatin-binding gelatinases that may cleave FN, reduce its stability and a...

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.2009.01241.x

    authors: Pal S,Chen Z,Xu X,Mikhailova M,Steffensen B

    更新日期:2010-04-01 00:00:00

  • Migration of epithelial cells on materials used in guided tissue regeneration.

    abstract::Materials used in guided tissue regeneration were examined in an in vitro model for regenerating human junctional epithelium. The extent of epithelial migration from gingival explants (epibolus) between the explant and an experimental substratum was significantly greater with a Millipore filter (HA) than with a teflon...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.1990.tb00907.x

    authors: Salonen JI,Persson GR

    更新日期:1990-07-01 00:00:00

  • A fluid-phase endocytotic capacity and intracellular degradation of a foreign protein (horseradish peroxidase) by lysosomal cysteine proteinases in the rat junctional epithelium.

    abstract::We investigated the co-localization of lysosomal cathepsins B, H and L, and horseradish peroxidase (HRP) in junctional epithelial (JE) cells both as a fluid-phase endocytotic marker to demonstrate the fluid-phase endocytotic capacity of JE cells, and to understand the morphological relationships of the endocytosed for...

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.1997.tb00575.x

    authors: Yamaza T,Kido MA,Kiyoshima T,Nishimura Y,Himeno M,Tanaka T

    更新日期:1997-11-01 00:00:00

  • Developmental changes of the vasculature in the periodontal ligament of rat molars: a scanning electron microscopic study of microcorrosion casts.

    abstract::Vascularization of the periodontal ligament was examined in developing upper first molars of rats from 5 to 30 d after birth with light and scanning electron microscopy. Formation of the vascular network in the periodontal ligament (PDL) started with the beginning of root formation. The PDL vessels derived from the ba...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0765.2000.035004201.x

    authors: Tsukada H,Ishikawa H,Nakamura S,Yoshida S

    更新日期:2000-08-01 00:00:00

  • Effects of cytomegalovirus infection on the mRNA expression of collagens and matrix metalloproteinases in gingival fibroblasts.

    abstract:BACKGROUND AND OBJECTIVE:The purpose of this in vitro investigation was to study the effects of human cytomegalovirus infection on the mRNA expression for collagens I and III and for matrix metalloproteinases 1 and 2 in gingival fibroblasts. MATERIAL AND METHODS:Gingival fibroblasts were experimentally infected with t...

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.2007.01053.x

    authors: Botero JE,Contreras A,Parra B

    更新日期:2008-12-01 00:00:00

  • Attachment, proliferation and differentiation of periodontal ligament cells on various guided tissue regeneration membranes.

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    doi:10.1034/j.1600-0765.2001.360508.x

    authors: Takata T,Wang HL,Miyauchi M

    更新日期:2001-10-01 00:00:00

  • Long junctional epithelium produced by application of bacterial protease in rats.

    abstract::In the present study, the effect of bacterial protease on the periodontal tissues in rats was investigated histologically and histometrically. In the control group, 0.03 ml distilled water was applied to the lingual marginal gingiva of the mandibular incisor while, in the experimental group, 0.03 ml bacterial protease...

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    authors: Suzumura Y,Kameyama Y,Mizutani M,Kato M,Kondo K,Mabuchi R

    更新日期:1989-05-01 00:00:00

  • Ultrastructure of cementogenesis as affected by growth hormone in the molar periodontium of the hypophysectomized rat.

    abstract::To document the effect of hypophysectomy and growth hormone replacement on the ultrastructure of cementogenesis in the developing rat third molar, 12 female Wistar rats were randomly allocated to normal control, hypophysectomized or hypophysectomized plus human growth hormone (for 10 days) treatment groups. The result...

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    doi:10.1111/j.1600-0765.1994.tb01221.x

    authors: Clayden AM,Young WG,Zhang CZ,Harbrow D,Romaniuk K,Waters MJ

    更新日期:1994-07-01 00:00:00

  • Retinoic acid is a potential negative regulator for differentiation of human periodontal ligament cells.

    abstract:BACKGROUND AND OBJECTIVES:Retinoic acid (RA) exerts a wide variety of effects on development, cellular differentiation and homeostasis in various tissues. However, little is known about the effects of RA on the differentiation of periodontal ligament cells. In this study, we investigated whether RA can affect the dexam...

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    doi:10.1111/j.1600-0765.2005.00811.x

    authors: Shibuya N,Nemoto E,Kanaya S,Kunii R,Shimauchi H

    更新日期:2005-12-01 00:00:00

  • Association analysis between the -2518MCP-1(A/G) polymorphism and generalized aggressive periodontitis in a Chinese population.

    abstract:BACKGROUND AND OBJECTIVE:It has been suggested that aggressive periodontitis has a genetic basis. Monocyte chemoattractant protein 1 (MCP-1) plays a critical role in the recruitment of monocytes and the development of periodontitis. The -2518MCP-1(A/G) polymorphism has been implicated as a risk or susceptibility factor...

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.2011.01426.x

    authors: Zhu XL,Meng HX,Zhang L,Xu L,Chen ZB,Shi D,Feng XH,Zhang X

    更新日期:2012-06-01 00:00:00

  • Oxidative burst intensity of peripheral phagocytic cells and periodontitis in Down syndrome.

    abstract:BACKGROUND:This study investigated the oxidative burst function of peripheral phagocytic cells (granulocytes and monocytes) and assessed the relation between oxidative burst and periodontal status in adult individuals with Down syndrome (DS) vs. other groups. METHODS:Of 55 DS individuals (18-56 years old), 74 individu...

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    pub_type: 杂志文章

    doi:10.1111/jre.12075

    authors: Khocht A,Russell B,Cannon JG,Turner B,Janal M

    更新日期:2014-02-01 00:00:00

  • Autoimmunity to collagen in adult periodontal disease: immunoglobulin classes in sera and tissue.

    abstract::The immunoglobulin class distribution of antibody to human collagen type I has been examined in sera and gingival extracts from patients with adult chronic periodontitis. Tissue extracts were made either by simple washing or ultrasonication. With either method, IgG and IgA antibodies to collagen were present in higher...

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.1992.tb02086.x

    authors: Anusaksathien O,Singh G,Matthews N,Dolby AE

    更新日期:1992-01-01 00:00:00

  • Increased interleukin-1 beta (IL-1 beta) concentration in gingival tissue from periodontitis patients.

    abstract::Human gingival tissues from periodontitis patients were found to contain from 126 fg/mg to 2161 fg/mg interleukin-1 beta as determined by a sensitive enzyme linked immunoassay. No IL-1 beta could be found in normal gingival tissue. This finding may have important consequences relevant to connective tissue destruction ...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.1989.tb00883.x

    authors: Hönig J,Rordorf-Adam C,Siegmund C,Wiedemann W,Erard F

    更新日期:1989-11-01 00:00:00

  • Cigarette smoke condensate inhibits collagen gel contraction and prostaglandin E2 production in human gingival fibroblasts.

    abstract:BACKGROUND:Granulation tissue remodeling and myofibroblastic differentiation are critically important events during wound healing. Tobacco smoking has a detrimental effect in gingival tissue repair. However, studies evaluating the effects of cigarette smoke on these events are lacking. MATERIAL AND METHODS:We used gin...

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    pub_type: 杂志文章

    doi:10.1111/jre.12216

    authors: Romero A,Cáceres M,Arancibia R,Silva D,Couve E,Martínez C,Martínez J,Smith PC

    更新日期:2015-06-01 00:00:00

  • Mechanisms involved in regulation of periodontal ligament cell production of pro-inflammatory cytokines: Implications in periodontitis.

    abstract::It is well recognized that human periodontal ligament cells (PDL cells) may represent local immune cells of the periodontal tissues. However, it is unclear whether they represent "true" immune cells, since they can produce pro-inflammatory cytokines not only after stimulation with bacterial lipopolysaccharides but als...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1111/jre.12823

    authors: Nilsson BO

    更新日期:2020-12-10 00:00:00

  • Detection of putative periodontal pathogens in non-insulin-dependent diabetes mellitus and non-diabetes mellitus by polymerase chain reaction.

    abstract::It has been assumed that there is a relationship between periodontal diseases and diabetes mellitus, however the putative periodontal microorganisms in non-diabetes mellitus (non-DM) individuals and non-insulin-dependent diabetes mellitus (NIDDM) patients have not been well studied. In this study, the detection rates ...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1034/j.1600-0765.2001.90613.x

    authors: Yuan K,Chang CJ,Hsu PC,Sun HS,Tseng CC,Wang JR

    更新日期:2001-02-01 00:00:00

  • Activation of cannabinoid receptor CB2 regulates osteogenic and osteoclastogenic gene expression in human periodontal ligament cells.

    abstract:BACKGROUND AND OBJECTIVE:Cannabinoid receptor CB2, expressed in osteoblasts and osteoclasts, plays a crucial role in the regulation of bone metabolism. Since periodontal ligament (PDL) cells can differentiate into osteoblasts, this study was undertaken to investigate CB2 expression and the effect of CB2 activation on o...

    journal_title:Journal of periodontal research

    pub_type: 杂志文章

    doi:10.1111/j.1600-0765.2009.01265.x

    authors: Qian H,Zhao Y,Peng Y,Han C,Li S,Huo N,Ding Y,Duan Y,Xiong L,Sang H

    更新日期:2010-08-01 00:00:00