Differential reactivity of anti-E-selectin monoclonal antibodies in human gingival tissue.

abstract：:Quantitative assessment of osseous changes attributable to periodontal disease is made possible by digital subtraction radiography. Tissues through which x rays travel to produce dental radiographs essential to this process alter the energy spectrum of the beam such that calibration errors result when densitometry is ...

journal_title：Journal of periodontal research

authors： Webber RL,Tzukert A,Ruttimann U

更新日期：1989-01-01 00:00:00

abstract：:The adherence of Actinomyces naeslundii to human buccal mucosa is mediated by specific interactions between the bacterial cell surface fimbriae and complementary beta-linked galactoside receptors on the epithelial cell surface. The buccal mucosa and the bacteria that colonize its surface are constantly bathed in saliv...

journal_title：Journal of periodontal research

authors： Babu JP,Dabbous MK,Abraham SN

更新日期：1991-03-01 00:00:00

abstract：:The goal of a single step therapy has been an important consideration in the development of guided tissue regeneration devices. It would spare the patient from the need for repeated surgery and eliminate many problems associated with a non-resorbable barrier. Animal studies of a collagen membrane extracted from porcin...

journal_title：Journal of periodontal research

authors： Lu HK,Lee SY,Lin FP

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Connective tissue grafts are frequently applied, together with Emdogain(®) , for root coverage. However, it is unknown whether fibroblasts from the gingiva and from the palate respond similarly to Emdogain. The aim of this study was therefore to evaluate the effect of Emdogain(®) on fibroblasts...

journal_title：Journal of periodontal research

authors： Gruber R,Stähli A,Miron RJ,Bosshardt DD,Sculean A

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Arecoline, an arecanut alkaloid present in the saliva of betel quid chewers, has been implicated in the pathogenesis of a variety of inflammatory oral diseases, including oral submucous fibrosis and periodontitis. To understand the molecular basis of arecoline action in epithelial changes assoc...

journal_title：Journal of periodontal research

authors： Thangjam GS,Kondaiah P

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Activated potassium channels were found to be strongly correlated with gingival overgrowth (GO) phenotype as we reviewed syndromic hereditary gingival fibromatosis (HGF). Nevertheless, the functional roles of potassium channels in gingival fibrosis or gingival overgrowth remained uncovered. The...

journal_title：Journal of periodontal research

authors： Gao Q,Yang C,Meng L,Wang Z,Chen D,Peng Y,Yang K,Bian Z

更新日期：2020-12-31 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interleukin-6 (IL-6) is a key proinflammatory cytokine that has been considered to be important in the pathogenesis of periodontal disease. Therefore, host-modulatory agents directed at inhibiting IL-6 appear to be beneficial in terms of attenuating periodontal disease progression and potential...

journal_title：Journal of periodontal research

authors： Jin JY,Choi EY,Park HR,Choi JI,Choi IS,Kim SJ

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:Developmental endothelial locus-1 (Del-1), lymphocyte function-associated antigen-1 (LFA-1), and interleukin 17 (IL-17) play critical roles in transendothelial migration of neutrophils in periodontal diseases. The aim of this study was to evaluate salivary Del-1, IL-17, and LFA-1 protein levels...

journal_title：Journal of periodontal research

authors： Inönü E,Kayis SA,Eskan MA,Hakki SS

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The expression of A Disintegrin and Metalloproteinase 8 (ADAM8) is associated with several inflammatory diseases. Elevated ADAM8 levels have been shown in gingival crevicular fluid of patients with chronic periodontitis. The objective of this study was to investigate ADAM8 expression in chroni...

journal_title：Journal of periodontal research

authors： Aung WPP,Chotjumlong P,Pata S,Montreekachon P,Supanchart C,Khongkhunthian S,Sastraruji T,Krisanaprakornkit S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Endotoxin tolerance is characterized by a state of hyporesponsiveness after confrontation with endotoxins such as lipopolysaccharides (LPS) at low concentrations. The aim of this study was to investigate, whether pretreatment with Porphyromonas gingivalis leads to endotoxin tolerance induction and...

journal_title：Journal of periodontal research

authors： Blufstein A,Behm C,Nguyen PQ,Rausch-Fan X,Andrukhov O

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Aggregatibacter actinomycetemcomitans is one of the etiological pathogens implicated in the onset of periodontal disease. This pathogen produces cytolethal distending toxin (CDT) that acts as a genotoxin to induce cell cycle arrest and cellular distension in cultured cell lines. Therefore, CDT is a possible ...

journal_title：Journal of periodontal research

authors： Ohara M,Miyauchi M,Tsuruda K,Takata T,Sugai M

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Obesity has been implicated as a risk factor for several chronic health conditions. Recent studies have reported a relationship between obesity and periodontitis, but few studies have investigated this relationship in adolescents. The purpose of the present study was to investigate the relation...

journal_title：Journal of periodontal research

authors： Ekuni D,Yamamoto T,Koyama R,Tsuneishi M,Naito K,Tobe K

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Chronic infections have been reported to be risk factors for coronary heart disease and ischemic stroke. However, the association of coronary heart disease and ischemic stroke with periodontal disease, which is also a chronic inflammatory disease, needs to be evaluated. The present case-control...

journal_title：Journal of periodontal research

authors： Pradeep AR,Hadge P,Arjun Raju P,Shetty SR,Shareef K,Guruprasad CN

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Autoimmune diseases, including atherosclerosis, diabetes mellitus and rheumatoid arthritis, can be triggered and aggravated by the pathogen-driven antigenic peptide from Porphyromonas gingivalis HSP60. P. gingivalis is the major pathogen of chronic periodontitis, which is a global epidemic prev...

journal_title：Journal of periodontal research

authors： Jeong E,Lee JY,Kim SJ,Choi J

更新日期：2012-12-01 00:00:00

abstract：:It is well recognized that human periodontal ligament cells (PDL cells) may represent local immune cells of the periodontal tissues. However, it is unclear whether they represent "true" immune cells, since they can produce pro-inflammatory cytokines not only after stimulation with bacterial lipopolysaccharides but als...

journal_title：Journal of periodontal research

authors： Nilsson BO

更新日期：2020-12-10 00:00:00

abstract：:Numerous studies report that water fluoridation reduces caries in children, but little current evidence exists about fluoridation's effects on the periodontal health of adults. To address this issue, we estimated fluoridation effects on periodontal disease among 1066 Washington state employees and their spouses, aged ...

journal_title：Journal of periodontal research

authors： Grembowski D,Fiset L,Spadafora A,Milgrom P

更新日期：1993-05-01 00:00:00

abstract：:The aim of this study was to conduct a systematic review to compare the clinical outcomes of two different resorbable collagen membranes in terms of regenerated bone volume, postoperative complications and membrane degradation during bone regeneration procedures. Randomized controlled trials (RCT) or controlled trials...

journal_title：Journal of periodontal research

authors： Jiménez Garcia J,Berghezan S,Caramês JMM,Dard MM,Marques DNS

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cannabinoid receptor CB2, expressed in osteoblasts and osteoclasts, plays a crucial role in the regulation of bone metabolism. Since periodontal ligament (PDL) cells can differentiate into osteoblasts, this study was undertaken to investigate CB2 expression and the effect of CB2 activation on o...

journal_title：Journal of periodontal research

authors： Qian H,Zhao Y,Peng Y,Han C,Li S,Huo N,Ding Y,Duan Y,Xiong L,Sang H

更新日期：2010-08-01 00:00:00

abstract：:Previous observations suggest that interleukin-1 (IL-1) may play an important role in the progression of periodontitis. In the present study, we investigated whether a cell-associated IL-1 alpha (CAIL-1 alpha) produced in human gingival fibroblasts (HGF) induces biological activities related to the progression of peri...

journal_title：Journal of periodontal research

authors： Okamatsu Y,Kobayashi M,Nishihara T,Hasegawa K

更新日期：1996-07-01 00:00:00

abstract：:Bursts of periodontal destruction are modelled as percolation-driven phase shift events. Percolation theory, though widely used to study the flow of liquids through porous nonliving materials (e.g., soils and rocks), can be applied to bacterial or toxicological penetration of living tissue in only an approximate sense...

journal_title：Journal of periodontal research

authors： Cohen ME

更新日期：1993-11-01 00:00:00

abstract：:The effectiveness of an ideal antimicrobial agent depends on its ability to kill microbes with minimal toxicity to host cells. Depending on the treatment regimen, antimicrobial agents come into contact with host cells for various intervals of time. Sanguinarium (SANG), chlorhexidine (CHX) and tetracycline (TET) are 3 ...

journal_title：Journal of periodontal research

authors： Agarwal S,Piesco NP,Peterson DE,Charon J,Suzuki JB,Godowski KC,Southard GL

更新日期：1997-04-01 00:00:00

abstract：:Interleukin-1 (IL-1) molecules, IL-1 alpha and IL-1 beta are cytokines involved in the acute-phase response against infection and in the pathogenesis of periodontal destruction. Administration of exogenous IL-1 receptor antagonist (IL-1ra) is effective in reducing the inflammatory reactions mediated by IL-1. However, ...

journal_title：Journal of periodontal research

authors： Ishihara Y,Nishihara T,Kuroyanagi T,Shirozu N,Yamagishi E,Ohguchi M,Koide M,Ueda N,Amano K,Noguchi T

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVES:Distinct periodontal phenotypes have been identified by cluster analysis, which is an explorative method with very low external validity. The aim of the present study was to investigate variance components of facial gingival thickness in young adults with mild gingivitis. MATERIAL AND METHODS:Thirty-three n...

journal_title：Journal of periodontal research

authors： Müller HP,Könönen E

更新日期：2005-06-01 00:00:00

abstract：:Epidermal growth factor (EGF) is a small molecular weight polypeptide which is thought to have important functions in epithelial growth and differentiation and in wound healing. EGF exerts its action on cells through binding to a cell surface receptor. Using immunohistochemistry and a monoclonal antibody (mAb) directe...

journal_title：Journal of periodontal research

authors： Nordlund L,Hormia M,Saxén L,Thesleff I

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Neutrophil extracellular traps (NETs) are a recently discovered antimicrobial mechanism used by neutrophils that have been proposed as an intervention in the pathogenesis of periodontitis. The objective of our study was to characterize the expression of NETs in gingival tissues with periodontit...

journal_title：Journal of periodontal research

authors： Magán-Fernández A,O'Valle F,Abadía-Molina F,Muñoz R,Puga-Guil P,Mesa F

更新日期：2019-06-01 00:00:00

abstract：:This umbrella review appraised existing systematic reviews and meta-analysis to establish the impact of periodontal disease and therapy on general and oral health-related quality of life. A systematic electronic literature search was carried out in accordance with the PRISMA guideline up to January 2020 using PubMed, ...

journal_title：Journal of periodontal research

authors： Wong LB,Yap AU,Allen PF

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Current epidemiological works have suggested that chronic infections, such as periodontitis, are associated with an increased risk of cardiovascular diseases, including hypertrophy and heart failure. However, mechanisms behind the association are not known. The aim of this study was to evaluate...

journal_title：Journal of periodontal research

authors： Köse O,Arabacı T,Gedikli S,Eminoglu DÖ,Kermen E,Kızıldağ A,Kara A,Ozkanlar S,Yemenoglu H

更新日期：2017-04-01 00:00:00

abstract：:Bradykinin stimulated production of prostaglandin E2 (PGE2) and the release of 3H-arachidonic acid by gingival fibroblasts in a time- and dose-dependent manner. The effect on PGE2 biosynthesis was seen already after 15 seconds and was maximal after 5 minutes. Several structurally unrelated inhibitors of arachidonic ac...

journal_title：Journal of periodontal research

authors： Modéer T,Ljunggren O,Lerner UH

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To ascertain whether interdental cleaning behaviours of Australian adults were associated with lower levels of plaque, gingivitis and periodontal disease. MATERIAL AND METHODS:Data were obtained from the National Survey of Adult Oral Health 2004-06. Outcome variables were three indicators of o...

journal_title：Journal of periodontal research

authors： Crocombe LA,Brennan DS,Slade GD,Loc DO

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:One of the major pathologic patterns in periodontitis represents an imbalance among the production of free radicals and local antioxidants resulting in periodontal tissue destruction. The objective of the study was to investigate the influence of non-surgical periodontal treatment on salivary a...

journal_title：Journal of periodontal research

authors： Novakovic N,Todorovic T,Rakic M,Milinkovic I,Dozic I,Jankovic S,Aleksic Z,Cakic S

更新日期：2014-02-01 00:00:00