Characterization and comparison of neutrophil extracellular traps in gingival samples of periodontitis and gingivitis: A pilot study.

abstract：BACKGROUND:This study investigated the oxidative burst function of peripheral phagocytic cells (granulocytes and monocytes) and assessed the relation between oxidative burst and periodontal status in adult individuals with Down syndrome (DS) vs. other groups. METHODS:Of 55 DS individuals (18-56 years old), 74 individu...

journal_title：Journal of periodontal research

authors： Khocht A,Russell B,Cannon JG,Turner B,Janal M

更新日期：2014-02-01 00:00:00

abstract：:Portions of clinically healthy non-keratinized and keratinized oral epithelia were removed from adult vervet monkeys (Cercopithecus aethiops). The epithelium was separated from the underlying lamina propria by trypsin digestion, following which the epithelial cells were separated from the various epithelial layers. ...

journal_title：Journal of periodontal research

authors： Cleaton-Jones P

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Occlusal trauma is an important factor that influences the progression of periodontitis, but it is unclear whether occlusal trauma influences periodontal destruction at the onset of periodontitis. We established an experimental periodontitis model with both site-specific loss of attachment and ...

journal_title：Journal of periodontal research

authors： Nakatsu S,Yoshinaga Y,Kuramoto A,Nagano F,Ichimura I,Oshino K,Yoshimura A,Yano Y,Hara Y

更新日期：2014-06-01 00:00:00

abstract：AIM:This subgroup analysis of a 12-week randomized, double-blind, and two-center trial aimed to evaluate whether two different toothpaste formulations can differentially modulate the dental microbiome. MATERIAL AND METHODS:Forty one mild to moderate periodontitis patients used as an adjunct to periodontal treatment ei...

journal_title：Journal of periodontal research

authors： Hagenfeld D,Prior K,Harks I,Jockel-Schneider Y,May TW,Harmsen D,Schlagenhauf U,Ehmke B

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:High-mobility-group box 1 functions as a late-phase inflammatory mediator. It can be released extracellularly by macrophages and necrotic cells through lipopolysaccharide and tumor necrosis factor-alpha. The objective of this study was to clarify the source of high-mobility-group box 1 in chron...

journal_title：Journal of periodontal research

authors： Morimoto Y,Kawahara KI,Tancharoen S,Kikuchi K,Matsuyama T,Hashiguchi T,Izumi Y,Maruyama I

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The aim of this immunocytochemical study was to characterize the expression and distribution of the progesterone receptor (PR) and estrogen receptor (ER) in gingival fibroblasts using culture cells derived from people at various ages. BACKGROUND:The reaction of female hormones is tissue or cell specific, and...

journal_title：Journal of periodontal research

authors： Kawahara K,Shimazu A

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Chronic infections have been reported to be risk factors for coronary heart disease and ischemic stroke. However, the association of coronary heart disease and ischemic stroke with periodontal disease, which is also a chronic inflammatory disease, needs to be evaluated. The present case-control...

journal_title：Journal of periodontal research

authors： Pradeep AR,Hadge P,Arjun Raju P,Shetty SR,Shareef K,Guruprasad CN

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The origin of cells in the mature periodontium, and the location of their progenitors, are still unknown. It is also unknown whether inflammation influences the number and distribution of these cells within the periodontium. Molecules such as STRO-1, CD146 and CD44 have been identified on a var...

journal_title：Journal of periodontal research

authors： Chen SC,Marino V,Gronthos S,Bartold PM

更新日期：2006-12-01 00:00:00

abstract：:The adherence of Actinomyces naeslundii to human buccal mucosa is mediated by specific interactions between the bacterial cell surface fimbriae and complementary beta-linked galactoside receptors on the epithelial cell surface. The buccal mucosa and the bacteria that colonize its surface are constantly bathed in saliv...

journal_title：Journal of periodontal research

authors： Babu JP,Dabbous MK,Abraham SN

更新日期：1991-03-01 00:00:00

abstract：:Recently, a relationship was demonstrated between the thickness of the cementum layer in rat molars and the activity of alkaline phosphatase (ALP) in the adjoining periodontal ligament (PDL). It was the aim of the present study to investigate whether such a relationship also exists in the periodontium of man. Healthy ...

journal_title：Journal of periodontal research

authors： van den Bos T,Beertsen W

更新日期：1999-01-01 00:00:00

abstract：:Nearly 70-75% of patients with localized juvenile periodontitis (JP) have abnormal polymorphonuclear leukocytic (PMN) chemotaxis. The objective of this study was to determine whether the lower chemotactic response in PMNs from JP patients is associated with a defect in intracellular signal transduction, as measured by...

journal_title：Journal of periodontal research

authors： Agarwal S,Reynolds MA,Duckett LD,Suzuki JB

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Long noncoding RNAs (lncRNAs) play critical and complex roles in regulating various biological processes of periodontitis. This bioinformatic study aims to construct a putative competing endogenous RNA (ceRNA) network by integrating lncRNA, miRNA and mRNA expression, based on high-throughput R...

journal_title：Journal of periodontal research

authors： Li S,Liu X,Li H,Pan H,Acharya A,Deng Y,Yu Y,Haak R,Schmidt J,Schmalz G,Ziebolz D

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Arecoline, an arecanut alkaloid present in the saliva of betel quid chewers, has been implicated in the pathogenesis of a variety of inflammatory oral diseases, including oral submucous fibrosis and periodontitis. To understand the molecular basis of arecoline action in epithelial changes assoc...

journal_title：Journal of periodontal research

authors： Thangjam GS,Kondaiah P

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Granulation tissue remodeling and myofibroblastic differentiation are critically important events during wound healing. Tobacco smoking has a detrimental effect in gingival tissue repair. However, studies evaluating the effects of cigarette smoke on these events are lacking. MATERIAL AND METHODS:We used gin...

journal_title：Journal of periodontal research

authors： Romero A,Cáceres M,Arancibia R,Silva D,Couve E,Martínez C,Martínez J,Smith PC

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The expression of A Disintegrin and Metalloproteinase 8 (ADAM8) is associated with several inflammatory diseases. Elevated ADAM8 levels have been shown in gingival crevicular fluid of patients with chronic periodontitis. The objective of this study was to investigate ADAM8 expression in chroni...

journal_title：Journal of periodontal research

authors： Aung WPP,Chotjumlong P,Pata S,Montreekachon P,Supanchart C,Khongkhunthian S,Sastraruji T,Krisanaprakornkit S

更新日期：2017-06-01 00:00:00

abstract：:The distribution of collagen types I and III was demonstrated in healthy periodontal tissues of the rat and marmoset using immunofluorescent localization after decalcification of the maxillae and mandiblae in 0.2 N HCl. An intense fluorescence in the alveolar bone and cementum matrix, as well as in the soft periodonta...

journal_title：Journal of periodontal research

authors： Romanos GE,Schröter-Kermani C,Hinz N,Wachtel HC,Bernimoulin JP

更新日期：1992-03-01 00:00:00

abstract：:The present study was carried out to examine the ultrastructural localization of laminin and type-IV collagen in the junctional epithelium of rat molar gingiva by means of the indirect immunoperoxidase method. Intense laminin reaction occurred in both the internal and the external basal laminae. Laminin reaction produ...

journal_title：Journal of periodontal research

authors： Sawada T,Yamamoto T,Yanagisawa T,Takuma S,Hasegawa H,Watanabe K

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Neutrophils are the primary white blood cells that are recruited to fight the initial phases of microbial infections. While healthy norms have been determined for circulating blood neutrophil counts in order to identify patients with suspected systemic infections, the levels of oral neutrophils...

journal_title：Journal of periodontal research

authors： Landzberg M,Doering H,Aboodi GM,Tenenbaum HC,Glogauer M

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Long-term tooth retention is the ultimate goal of periodontal therapy. Aim of this study was to evaluate tooth loss (TL) during 10 years of supportive periodontal therapy (SPT) in periodontal compromised patients and to identify factors influencing TL on patient level. MATERIAL AND METHODS:Pat...

journal_title：Journal of periodontal research

authors： Petsos H,Schacher B,Ramich T,Nickles K,Dannewitz B,Arendt S,Seidel K,Eickholz P

更新日期：2020-12-01 00:00:00

abstract：:This study investigated the cell surface expression of CD11b (Mo 1, Mac-1, CR 3) by neutrophils (PMNs) from human crevicular fluid (CF-PMNs). CD11b expression on CF-PMNs was compared, using flow cytometry, to that on peripheral blood PMNs (PB-PMNs) isolated simultaneously from the same subjects. CD11b expression by CF...

journal_title：Journal of periodontal research

authors： Watanabe K,Hagen KL,Andersen BR

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:beta defensin antimicrobial peptides are important in epithelial innate immunity, and their differential expression is associated with periodontal diseases. The aims of this study were to determine the mRNA expression of human beta defensin-1 and -2 in the gingival tissue of patients with gingi...

journal_title：Journal of periodontal research

authors： Vardar-Sengul S,Demirci T,Sen BH,Erkizan V,Kurulgan E,Baylas H

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Urokinase-plasminogen activator (uPA) is a serine protease expressed at high basal level in normal gingival cervical fluid. Despite its known pathologic role in tissue proteolysis in periodontitis, little is known concerning uPA physiological function in oral tissue. Recent evidence in cancer c...

journal_title：Journal of periodontal research

authors： Ahmad Akhoundi MS,Rokn A,Bagheri R,Momeni N,Hodjat M

更新日期：2018-10-01 00:00:00

abstract：:Hereditary gingival fibromatosis (HGF) is an oral condition characterized by the enlargement of the gingiva of both the maxilla and mandible. To study the cell proliferation index of fibroblasts from HGF and normal gingiva (NG), cell cultures from 4 members of the same family with HGF and from 4 healthy patients were ...

journal_title：Journal of periodontal research

authors： Coletta RD,Almeida OP,Graner E,Page RC,Bozzo L

更新日期：1998-11-01 00:00:00

abstract：:Black-pigmented bacteria which produce cytotoxic metabolic end-products and cell membrane-associated proteases have been reported to play an important role in the pathogenesis of periodontal diseases. These bacterial virulence factors can be modified by the environmental conditions including nutrients supplied various...

journal_title：Journal of periodontal research

authors： Saito K,Takahashi N,Horiuchi H,Yamada T

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The field of salivary diagnostics lacks an accepted and validated biomarker of alveolar bone remodeling. To address this, we examined levels of salivary biomolecules specifically associated with biological aspects of bone remodeling in subjects with chronic periodontitis in a case-control study...

journal_title：Journal of periodontal research

authors： Al-Sabbagh M,Alladah A,Lin Y,Kryscio RJ,Thomas MV,Ebersole JL,Miller CS

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The prevalence of chronic renal disease in industrialized countries is increasing, and chronic renal disease and periodontitis can have significant, reciprocal effects. The aim of this study was to evaluate the associations between specific clinical parameters and the levels of tumor necrosis f...

journal_title：Journal of periodontal research

authors： Dağ A,Firat ET,Kadiroğlu AK,Kale E,Yilmaz ME

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:T cells and their cytokines are believed to be key factors in periodontal disease and bone resorption. We previously showed that T cells transferred to nude mice were related to inflammatory bone resorption in vivo. However, it has not been clarified whether T cells can induce bone resorption i...

journal_title：Journal of periodontal research

authors： Yamaguchi M,Ukai T,Kaneko T,Yoshinaga M,Yokoyama M,Ozaki Y,Hara Y

更新日期：2008-10-01 00:00:00

abstract：:E-selectin is a cytokine-inducible endothelial glycoprotein which participates in the binding of leukocytes to vascular endothelium. Variable levels of expression of E-selectin have been reported in gingivitis and periodontitis, and two differing concepts of its significance have emerged: either gingival blood vessels...

journal_title：Journal of periodontal research

authors： Pietrzak ER,Savage NW,Xu LJ,Walsh LJ

更新日期：1995-11-01 00:00:00

abstract：:A single-blind investigation was designed to study the effects of piroxicam in preventing gingival inflammation and plaque formation in beagle dogs. Twelve 1-year-old beagles were brought to optimum oral hygiene and gingival health. Thereafter, they were fed a moist plaque-promoting diet and were divided into three gr...

journal_title：Journal of periodontal research

authors： Howell TH,Fiorellini J,Weber HP,Williams RC

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Little is known about the factors that affect the microbial composition of supragingival biofilms. This study was designed to examine the relationship between total DNA probe counts of supragingival biofilm samples, clinical parameters and supragingival biofilm composition. MATERIAL AND METHOD...

journal_title：Journal of periodontal research

authors： Haffajee AD,Teles RP,Patel MR,Song X,Veiga N,Socransky SS

更新日期：2009-08-01 00:00:00