Oxidative burst intensity of peripheral phagocytic cells and periodontitis in Down syndrome.

abstract：:Growth factors are known to play a major role in the regeneration of the periodontium. Basic fibroblast growth factor (bFGF) is a polypeptide growth factor considered to have a role in chemotaxis and mitogenesis of periodontal ligament (PDL) cells. The aim of this study was to assess the effect of bFGF on the transcri...

journal_title：Journal of periodontal research

authors： Palmon A,Roos H,Reichenberg E,Grosskop A,Bar Kana I,Pitaru S,Redlich M

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Alveolar bone resorption is a characteristic feature of periodontal diseases and involves removal of both the mineral and the organic constituents of the bone matrix, a process mainly carried out by multinucleated osteoclast cells. (-)-Epigallocatechin gallate, the main constituent of green tea...

journal_title：Journal of periodontal research

authors： Yun JH,Kim CS,Cho KS,Chai JK,Kim CK,Choi SH

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The combination of EMD with root-coverage procedures has been shown to promote periodontal regeneration on the exposed root surface. The aim of this randomized clinical study was to compare the efficacy of EMD with connective tissue graft (CTG) for the treatment of Miller Class I and Class II s...

journal_title：Journal of periodontal research

authors： Alkan EA,Parlar A

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Vitamin D-1,25(OH)2 D3 or 1,25D3-maintains healthy osseous tissue, stimulates the production of the antimicrobial peptide cathelicidin and has anti-inflammatory effects, but it can cause hypercalcemia. Evidence links diminished serum levels of 1,25D3 with increased gingival inflammation. Period...

journal_title：Journal of periodontal research

authors： Nakashyan V,Tipton DA,Karydis A,Livada R,Stein SH

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:Heat shock protein (HSP) can be utilized as a vaccine to cross-protect against multiple pathogenic species. The present study was performed to evaluate Porphyromonas gingivalis heat shock protein 60 (HSP60) as a vaccine candidate to inhibit multiple bacteria-induced alveolar bone loss. MATERIAL AND METHODS:...

journal_title：Journal of periodontal research

authors： Lee JY,Yi NN,Kim US,Choi JS,Kim SJ,Choi JI

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Treponema denticola is a key pathogen associated with periodontitis, a chronic inflammatory disease affecting tooth-supporting tissues. In the present study, we investigated the response of human macrophage-like cells to stimulation by peptidoglycan isolated from T. denticola. We also studied t...

journal_title：Journal of periodontal research

authors： Tanabe SI,Bodet C,Grenier D

更新日期：2009-08-01 00:00:00

abstract：:This study investigated the cell surface expression of CD11b (Mo 1, Mac-1, CR 3) by neutrophils (PMNs) from human crevicular fluid (CF-PMNs). CD11b expression on CF-PMNs was compared, using flow cytometry, to that on peripheral blood PMNs (PB-PMNs) isolated simultaneously from the same subjects. CD11b expression by CF...

journal_title：Journal of periodontal research

authors： Watanabe K,Hagen KL,Andersen BR

更新日期：1991-03-01 00:00:00

abstract：:Hereditary gingival fibromatosis (HGF) is an oral condition characterized by the enlargement of the gingiva of both the maxilla and mandible. To study the cell proliferation index of fibroblasts from HGF and normal gingiva (NG), cell cultures from 4 members of the same family with HGF and from 4 healthy patients were ...

journal_title：Journal of periodontal research

authors： Coletta RD,Almeida OP,Graner E,Page RC,Bozzo L

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study aimed to assess the effectiveness of the treatment with alpha-terpineol (αTPN) complexed with beta-cyclodextrin (βCD) on oral, blood, and hepatic parameters in ligature-induced periodontitis. MATERIAL AND METHODS:Forty female rats were distributed among the following groups: control...

journal_title：Journal of periodontal research

authors： Vasconcelos ACCG,Vasconcelos DFP,da Silva FRP,França LFC,Alves EHP,Di Lenardo D,Pessoa LDS,Nascimento HMS,Carvalho ADS,Sousa FBM,Barbosa ALDR,Medeiros JR,Novaes PD,Mariano FS,Lima BDS,Araujo AAS,Júnior LJQ,de Oliveira A

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Arecoline, an arecanut alkaloid present in the saliva of betel quid chewers, has been implicated in the pathogenesis of a variety of inflammatory oral diseases, including oral submucous fibrosis and periodontitis. To understand the molecular basis of arecoline action in epithelial changes assoc...

journal_title：Journal of periodontal research

authors： Thangjam GS,Kondaiah P

更新日期：2009-10-01 00:00:00

abstract：:Epidermal growth factor (EGF) is a small molecular weight polypeptide which is thought to have important functions in epithelial growth and differentiation and in wound healing. EGF exerts its action on cells through binding to a cell surface receptor. Using immunohistochemistry and a monoclonal antibody (mAb) directe...

journal_title：Journal of periodontal research

authors： Nordlund L,Hormia M,Saxén L,Thesleff I

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Elevated nitric oxide (NO) has been associated with destructive periodontal disease. The aim of the present study was to test the hypothesis that exogenous NO may inhibit a protective immune response to Aggregatibacter actinomycetemcomitans lipopolysaccharide (LPS) in a murine model. MATERIAL ...

journal_title：Journal of periodontal research

authors： Sosroseno W,Bird PS,Seymour GJ

更新日期：2009-08-01 00:00:00

abstract：:Fibroblast function in gingival tissue is thought to be regulated by the local cellular environment--both the extracellular matrix and soluble factors. In an attempt to artificially re-create this situation fibroblasts have been cultured within 3-dimensional collagen gels in an environment more physiologically compara...

journal_title：Journal of periodontal research

authors： Irwin CR,Schor SL,Ferguson MW

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Retinoic acid (RA) exerts a wide variety of effects on development, cellular differentiation and homeostasis in various tissues. However, little is known about the effects of RA on the differentiation of periodontal ligament cells. In this study, we investigated whether RA can affect the dexam...

journal_title：Journal of periodontal research

authors： Shibuya N,Nemoto E,Kanaya S,Kunii R,Shimauchi H

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To study the expression and role in vigabatrin (VGB)-induced gingival enlargement of Ki-67 antigen and p27KIP1, p21WAF1, and p53, proteins that activate or inhibit cell-cycle progression. MATERIALS AND METHODS:Six patients treated with VGB for partial epileptic seizures refractory to classic anticonvulsant t...

journal_title：Journal of periodontal research

authors： Mesa F,Aguilar M,Gonzalez-Moles MA,Guerrero A,Sanchez-Alvarez JC,Del Moral RG,O'Valle F

更新日期：2004-02-01 00:00:00

abstract：:The adherence of Actinomyces naeslundii to human buccal mucosa is mediated by specific interactions between the bacterial cell surface fimbriae and complementary beta-linked galactoside receptors on the epithelial cell surface. The buccal mucosa and the bacteria that colonize its surface are constantly bathed in saliv...

journal_title：Journal of periodontal research

authors： Babu JP,Dabbous MK,Abraham SN

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to investigate reactions of periodontal ligament epithelial cell clusters and major histocompatibility complex class II (OX6)-immunopositive cells to simultaneously induced tooth movement and periodontitis employing Waldo's method. MATERIAL AND METHODS:Elastic gums we...

journal_title：Journal of periodontal research

authors： Tadokoro O,Kawahara I,Vandevska-Radunovic V

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Periodontitis may alter the systemic condition in patients with diabetes and hence interfere with glycemic control. The objective of this study was to determine the quantifiable changes in glycated hemoglobin (HbA1C) after periodontal non-surgical therapy plus azithromycin in a mixed population...

journal_title：Journal of periodontal research

authors： Botero JE,Yepes FL,Ochoa SP,Hincapie JP,Roldan N,Ospina CA,Castrillon CA,Becerra MA

更新日期：2013-12-01 00:00:00

abstract：:Polymorphonuclear neutrophils (PMNs) are essential in host defense against periodontopathic bacteria such as Porphyromonas gingivalis. The uptake of immunoglobulin G (IgG)-opsonized bacteria via IgG Fc receptors (Fc gamma R) on PMN constitutes a central defense mechanism in periodontium. Fc gamma RIIIb is the most abu...

journal_title：Journal of periodontal research

authors： Kobayashi T,van der Pol WL,van de Winkel JG,Hara K,Sugita N,Westerdaal NA,Yoshie H,Horigome T

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The field of salivary diagnostics lacks an accepted and validated biomarker of alveolar bone remodeling. To address this, we examined levels of salivary biomolecules specifically associated with biological aspects of bone remodeling in subjects with chronic periodontitis in a case-control study...

journal_title：Journal of periodontal research

authors： Al-Sabbagh M,Alladah A,Lin Y,Kryscio RJ,Thomas MV,Ebersole JL,Miller CS

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The gingiva is the first oral tissue directly exposed to cigarette smoke (CS). Exposure to CS compromises the structure and function of gingival tissue. Damaging or altering the gingival epithelium leads to a compromised protective barrier of the periodontium, resulting in several diseases. The...

journal_title：Journal of periodontal research

authors： Alharbi IA,Rouabhia M

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To describe the periodontal conditions among 30-39- and 50-59-year-old rural Thais from the Province of Songkhla, Southern Thailand. METHODS:A total of 359 dentate persons were given a clinical examination comprising recordings of plaque and calculus in six teeth, and bleeding on probing, attachment level an...

journal_title：Journal of periodontal research

authors： Baelum V,Pisuithanakan S,Teanpaisan R,Pithpornchaiyakul W,Pongpaisal S,Papapanou PN,Dahlén G,Fejerskov O

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Periodontal disease has been described as playing a role in the atherosclerosis process, and its relation with intimal thickness and vascular endothelial function (EF) has been investigated. The present study sought to determine whether there are differences in parameters of arterial stiffness ...

journal_title：Journal of periodontal research

authors： Nicolosi LN,Lewin PG,Rudzinski JJ,Pompeo M,Guanca F,Rodríguez P,Gelpi RJ,Rubio MC

更新日期：2017-02-01 00:00:00

abstract：:To document the effect of hypophysectomy and growth hormone replacement on the ultrastructure of cementogenesis in the developing rat third molar, 12 female Wistar rats were randomly allocated to normal control, hypophysectomized or hypophysectomized plus human growth hormone (for 10 days) treatment groups. The result...

journal_title：Journal of periodontal research

authors： Clayden AM,Young WG,Zhang CZ,Harbrow D,Romaniuk K,Waters MJ

更新日期：1994-07-01 00:00:00

abstract：:The cytolethal distending toxin (Cdt) of Actinobacillus actinomycetemcomitans, a periodontal pathogen, is a newly described cytotoxin with immunosuppressive properties, capable of causing cell cycle arrest of lymphocytes. The objectives of this study were to investigate the occurrence of A. actinomycetemcomitans with ...

journal_title：Journal of periodontal research

authors： Tan KS,Song KP,Ong G

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:PTH plays an important role in bone remodeling, and different actions have been reported depending on its administration method. iPSCs are promising as a cell source for regeneration of periodontal tissue due to their ability of proliferation and pluripotency. However, the effects of PTH on iPSCs ...

journal_title：Journal of periodontal research

authors： Sato M,Aoki H,Nakamura T,Onodera S,Yamaguchi A,Saito A,Azuma T

更新日期：2020-10-01 00:00:00

abstract：:Colonization or emergence of microbial pathogens may result in tissue destruction by activation of one or more of five distinct host degradative pathways (matrix metalloproteinase pathway, plasminogen-dependent pathway, phagocytic pathway, PMN-serine proteinase pathway and osteoclastic bone resorption) or by direct cl...

journal_title：Journal of periodontal research

authors： Birkedal-Hansen H

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cigarette smoking is a major risk factor for periodontitis, and smoking perturbs neutrophil reactive oxygen species production. This study tested the hypothesis that cigarette smoke extract (CSE) and its components/metabolites nicotine, cotinine and thiocyanate (SCN-), may influence neutrophil ...

journal_title：Journal of periodontal research

authors： White PC,Hirschfeld J,Milward MR,Cooper PR,Wright HJ,Matthews JB,Chapple ILC

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Enamel matrix proteins are involved in the development and regeneration of root cementum and in its attachment to dentin; however, the mechanisms through which this occurs have yet to be elucidated. The present study was therefore carried out to evaluate the mitogenic and proliferative response...

journal_title：Journal of periodontal research

authors： Khedmat S,Seyedabadi M,Ghahremani MH,Ostad SN

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Current epidemiological works have suggested that chronic infections, such as periodontitis, are associated with an increased risk of cardiovascular diseases, including hypertrophy and heart failure. However, mechanisms behind the association are not known. The aim of this study was to evaluate...

journal_title：Journal of periodontal research

authors： Köse O,Arabacı T,Gedikli S,Eminoglu DÖ,Kermen E,Kızıldağ A,Kara A,Ozkanlar S,Yemenoglu H

更新日期：2017-04-01 00:00:00