Cigarette smoke modifies neutrophil chemotaxis, neutrophil extracellular trap formation and inflammatory response-related gene expression.

abstract：BACKGROUND AND OBJECTIVE:Treponema denticola is a key pathogen associated with periodontitis, a chronic inflammatory disease affecting tooth-supporting tissues. In the present study, we investigated the response of human macrophage-like cells to stimulation by peptidoglycan isolated from T. denticola. We also studied t...

journal_title：Journal of periodontal research

authors： Tanabe SI,Bodet C,Grenier D

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To describe the periodontal conditions among 30-39- and 50-59-year-old rural Thais from the Province of Songkhla, Southern Thailand. METHODS:A total of 359 dentate persons were given a clinical examination comprising recordings of plaque and calculus in six teeth, and bleeding on probing, attachment level an...

journal_title：Journal of periodontal research

authors： Baelum V,Pisuithanakan S,Teanpaisan R,Pithpornchaiyakul W,Pongpaisal S,Papapanou PN,Dahlén G,Fejerskov O

更新日期：2003-04-01 00:00:00

abstract：:An accumulation of elevated numbers of macrophages (M phi) and Ig producing cells is associated with localized and chronically inflamed gingiva of patients with adult periodontitis. When gingival lymphocytes were isolated from inflamed tissues and examined by flow cytometry, approximately 20-30% of lymphocytes were CD...

journal_title：Journal of periodontal research

authors： Yamamoto M,Fujihashi K,Hiroi T,McGhee JR,Van Dyke TE,Kiyono H

更新日期：1997-01-01 00:00:00

abstract：:The stepwise approach to the determination of periodontal attachment loss involves fitting linear, logarithmic, and exponential models to individual site data and concluding that the form of loss is consistent with the model that has the greatest r-value, provided that the model predicts loss in excess of a site-speci...

journal_title：Journal of periodontal research

authors： Cohen ME

更新日期：1996-01-01 00:00:00

abstract：:The periodontium is a highly hierarchically organized organ composed of gingiva, alveolar bone, periodontal ligament and cementum. Periodontitis leads to the destruction of hard and soft tissues ultimately leading to a loss of the teeth supporting apparatus. Current treatments are capable of limiting the disease progr...

journal_title：Journal of periodontal research

authors： Staples RJ,Ivanovski S,Vaquette C

更新日期：2020-06-01 00:00:00

abstract：:Multinucleated cells (MNCs) that appeared after hydroxyapatite (HAP) implantation into experimentally-produced bone defects in rat periodontal tissues were investigated both ultrastructurally and ultracytochemically. At day 5 after implantation, MNCs first appeared along the HAP surface. They had no features of typica...

journal_title：Journal of periodontal research

authors： Kawaguchi H,Ogawa T,Shirakawa M,Okamoto H,Akisaka T

更新日期：1992-01-01 00:00:00

abstract：:Diploid fibroblasts obtained from explants of human gingiva and maintained in vitro undergo a several-fold decrease in protein and collagen synthesis as a function of increasing donor age. Using drug-induced gingival hyperplasia as a model, we performed experiments to learn whether fibroblasts derived from hyperplasti...

journal_title：Journal of periodontal research

authors： Johnson BD,Narayanan AS,Pieters HP,Page RC

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Aggregatibacter actinomycetemcomitans is one of the etiological pathogens implicated in the onset of periodontal disease. This pathogen produces cytolethal distending toxin (CDT) that acts as a genotoxin to induce cell cycle arrest and cellular distension in cultured cell lines. Therefore, CDT is a possible ...

journal_title：Journal of periodontal research

authors： Ohara M,Miyauchi M,Tsuruda K,Takata T,Sugai M

更新日期：2011-06-01 00:00:00

abstract：:Recently, nitric oxide (NO) has been shown to be vital in inflammatory processes. Nitric oxide synthase (NOS) exists in three different isoforms, two constitutively produced with physiological roles, and an inducible form, iNOS, which is involved in inflammation. This study examined the localisation of iNOS in biopsie...

journal_title：Journal of periodontal research

authors： Lappin DF,Kjeldsen M,Sander L,Kinane DF

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study aimed to assess the effectiveness of the treatment with alpha-terpineol (αTPN) complexed with beta-cyclodextrin (βCD) on oral, blood, and hepatic parameters in ligature-induced periodontitis. MATERIAL AND METHODS:Forty female rats were distributed among the following groups: control...

journal_title：Journal of periodontal research

authors： Vasconcelos ACCG,Vasconcelos DFP,da Silva FRP,França LFC,Alves EHP,Di Lenardo D,Pessoa LDS,Nascimento HMS,Carvalho ADS,Sousa FBM,Barbosa ALDR,Medeiros JR,Novaes PD,Mariano FS,Lima BDS,Araujo AAS,Júnior LJQ,de Oliveira A

更新日期：2020-12-01 00:00:00

abstract：:Using the high iron diamine thiocarbohydrazide silver proteinate (HID-TCH-SP) staining technique, we investigated ultrastructural localization of sulfated glycosaminoglycans (GAGs) in the rat gingiva shortly after eruption, especially those associated with internal and external basal laminae. In the apical portion of ...

journal_title：Journal of periodontal research

authors： Kogaya Y,Haruna S,Vojinovic J,Iwayama Y,Akisaka T

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:PTH plays an important role in bone remodeling, and different actions have been reported depending on its administration method. iPSCs are promising as a cell source for regeneration of periodontal tissue due to their ability of proliferation and pluripotency. However, the effects of PTH on iPSCs ...

journal_title：Journal of periodontal research

authors： Sato M,Aoki H,Nakamura T,Onodera S,Yamaguchi A,Saito A,Azuma T

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to investigate reactions of periodontal ligament epithelial cell clusters and major histocompatibility complex class II (OX6)-immunopositive cells to simultaneously induced tooth movement and periodontitis employing Waldo's method. MATERIAL AND METHODS:Elastic gums we...

journal_title：Journal of periodontal research

authors： Tadokoro O,Kawahara I,Vandevska-Radunovic V

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to evaluate the effect of radiotherapy on the osseointegration of dental implants in the tibia and the action of platelet-rich plasma (PRP) as an adjuvant therapy. MATERIAL AND METHODS:A total of 18 rabbits received two implants in each tibial epiphysis, totalizing 7...

journal_title：Journal of periodontal research

authors： Ocaña RP,Rabelo GD,Sassi LM,Rodrigues VP,Alves FA

更新日期：2017-06-01 00:00:00

abstract：:Nearly 70-75% of patients with localized juvenile periodontitis (JP) have abnormal polymorphonuclear leukocytic (PMN) chemotaxis. The objective of this study was to determine whether the lower chemotactic response in PMNs from JP patients is associated with a defect in intracellular signal transduction, as measured by...

journal_title：Journal of periodontal research

authors： Agarwal S,Reynolds MA,Duckett LD,Suzuki JB

更新日期：1989-03-01 00:00:00

abstract：:The matrix metalloproteinases (MMPs) collagenase, gelatinase A (72 kDa gelatinase), stromelysin, and their specific inhibitor TIMP-1 (tissue inhibitor of metalloproteinases), were immunolocalized using specific polyclonal antisera in gingival tissues from 21 patients with chronic inflammatory periodontal disease. Mono...

journal_title：Journal of periodontal research

authors： Meikle MC,Hembry RM,Holley J,Horton C,McFarlane CG,Reynolds JJ

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:During cyclosporine-induced gingival overgrowth, the homeostatic balance of gingival connective tissue is disrupted leading to fibrosis. Galectins are glycan-binding proteins that can modulate a variety of cellular processes including fibrosis in several organs. Here, we study the role of galec...

journal_title：Journal of periodontal research

authors： Smith PC,Metz C,de la Peña A,Oyanadel C,Avila P,Arancibia R,Vicuña L,Retamal C,Barake F,González A,Soza A

更新日期：2020-10-01 00:00:00

abstract：:The effectiveness of an ideal antimicrobial agent depends on its ability to kill microbes with minimal toxicity to host cells. Depending on the treatment regimen, antimicrobial agents come into contact with host cells for various intervals of time. Sanguinarium (SANG), chlorhexidine (CHX) and tetracycline (TET) are 3 ...

journal_title：Journal of periodontal research

authors： Agarwal S,Piesco NP,Peterson DE,Charon J,Suzuki JB,Godowski KC,Southard GL

更新日期：1997-04-01 00:00:00

abstract：:The cellular heterogeneity of Malassez epithelium (ME) residing in the periodontal ligament has recently been reported, and the presence and coexistence of the neuropeptides calcitonin gene-related peptide (CGRP), substance P (SP) and vasoactive intestinal peptide (VIP) in single cells in ME has been shown (1). Howeve...

journal_title：Journal of periodontal research

authors： Tadokoro O,Maeda T,Heyeraas KJ,Vandevska-Radunovic V,Kozawa Y,Hals Kvinnsland I

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Naringenin, a naturally occurring flavonoid, possesses a wide range of pharmacological properties. The purpose of this study was to investigate the effect of naringenin on human osteoclastogenesis and osteoclastic bone resorption. MATERIAL AND METHODS:Naringenin was tested in a human osteoclas...

journal_title：Journal of periodontal research

authors： La VD,Tanabe S,Grenier D

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Probiotics create a biofilm and protect the oral tissues against the action of periodontal pathogenic bacteria. The aim of this study was to evaluate the effects of the oral probiotic Lactobacillus reuteri Prodentis upon the peri-implant health of edentulous patients with dental implants and p...

journal_title：Journal of periodontal research

authors： Flichy-Fernández AJ,Ata-Ali J,Alegre-Domingo T,Candel-Martí E,Ata-Ali F,Palacio JR,Peñarrocha-Diago M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Porphyromonas gingivalis, a black-pigmented, gram-negative anaerobe, is found in periodontitis lesions and its presence in subgingival plaque significantly increases the risk for periodontitis. We have previously shown that patients with aggressive forms of periodontitis that are seropositive for P. gingival...

journal_title：Journal of periodontal research

authors： Califano JV,Chou D,Lewis JP,Rogers JD,Best AM,Schenkein HA

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase and have anti-inflammatory effects independent of cholesterol lowering. Recent clinical studies have indicated that statin intake has a beneficial effect on periodontal disease. However, the underlying mechanisms have not...

journal_title：Journal of periodontal research

authors： Jin J,Zhang X,Lu Z,Li Y,Lopes-Virella MF,Yu H,Haycraft CJ,Li Q,Kirkwood KL,Huang Y

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Postranslational modification of proteins can lead to the production of autoantibodies and loss of immune tolerance. This process has been hypothesised to be a critical factor in the pathogenesis of rheumatoid arthritis. The objective of this study was to demonstrate that inflamed human gingiva...

journal_title：Journal of periodontal research

authors： Bright R,Thiele GM,Manavis J,Mikuls TR,Payne JB,Bartold PM

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:To evaluate the association between periodontal disease, tooth loss and coronary heart disease (CHD). There is still controversy about the relationship between periodontal disease and tooth loss with vessel obstruction assessed using coronary angiography. MATERIAL AND METHODS:This cross-sectio...

journal_title：Journal of periodontal research

authors： Zanella SM,Pereira SS,Barbisan JN,Vieira L,Saba-Chujfi E,Haas AN,Rösing CK

更新日期：2016-04-01 00:00:00

abstract：:The immunoglobulin class distribution of antibody to human collagen type I has been examined in sera and gingival extracts from patients with adult chronic periodontitis. Tissue extracts were made either by simple washing or ultrasonication. With either method, IgG and IgA antibodies to collagen were present in higher...

journal_title：Journal of periodontal research

authors： Anusaksathien O,Singh G,Matthews N,Dolby AE

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Polycan is a promising candidate for the treatment of periodontal disease. This study was undertaken to examine whether Polycan, a type of β-glucan, has a protective effect on ligature-induced experimental periodontitis and related alveolar bone loss in Sprague-Dawley rats. MATERIAL AND METHOD...

journal_title：Journal of periodontal research

authors： Kim YS,Kang SJ,Kim JW,Cho HR,Moon SB,Kim KY,Lee HS,Han CH,Ku SK,Lee YJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:T cells and their cytokines are believed to be key factors in periodontal disease and bone resorption. We previously showed that T cells transferred to nude mice were related to inflammatory bone resorption in vivo. However, it has not been clarified whether T cells can induce bone resorption i...

journal_title：Journal of periodontal research

authors： Yamaguchi M,Ukai T,Kaneko T,Yoshinaga M,Yokoyama M,Ozaki Y,Hara Y

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:CYP1A1 rs1048943 polymorphism was reported to be correlated with periodontitis; however, its association with aggressive periodontitis (AgP) has not yet been investigated. The aim of the study was to investigate the association between the CYP1A1 gene rs1048943 variant with generalized aggressi...

journal_title：Journal of periodontal research

authors： Wang X,Li W,Song W,Xu L,Zhang L,Feng X,Lu R,Meng H

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The gingival epithelium is a first line of defense against bacterial challenge. E-cadherin (E-cad) plays an important role in cell-cell adhesion as a barrier in the epithelium. Recently, a decrease in the expression of E-cad has been observed in inflamed gingival tissue. The aims of this study ...

journal_title：Journal of periodontal research

authors： Abe-Yutori M,Chikazawa T,Shibasaki K,Murakami S

更新日期：2017-02-01 00:00:00