Differential proliferation of fibroblasts cultured from hereditary gingival fibromatosis and normal gingiva.

abstract：:An epidemiological association between periodontitis and cardiovascular disease has been reported in multiple studies. Various mechanisms have been proposed as potential explanations for this association, including a common factor that predisposes certain individuals to a hyper-responsive inflammatory response. Variat...

journal_title：Journal of periodontal research

authors： Kornman KS,Pankow J,Offenbacher S,Beck J,di Giovine F,Duff GW

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Neutrophil extracellular traps (NETs) are a recently discovered antimicrobial mechanism used by neutrophils that have been proposed as an intervention in the pathogenesis of periodontitis. The objective of our study was to characterize the expression of NETs in gingival tissues with periodontit...

journal_title：Journal of periodontal research

authors： Magán-Fernández A,O'Valle F,Abadía-Molina F,Muñoz R,Puga-Guil P,Mesa F

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The role of water in the etiology of periodontal disease is poorly understood. OBJECTIVES:The objective of this study was to examine the association amongst water softness, risk for periodontitis, and smoking status. METHODS:We examined the association between use of water 'softening and conditioning syste...

journal_title：Journal of periodontal research

authors： Wood N,Johnson RB

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:beta defensin antimicrobial peptides are important in epithelial innate immunity, and their differential expression is associated with periodontal diseases. The aims of this study were to determine the mRNA expression of human beta defensin-1 and -2 in the gingival tissue of patients with gingi...

journal_title：Journal of periodontal research

authors： Vardar-Sengul S,Demirci T,Sen BH,Erkizan V,Kurulgan E,Baylas H

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Obesity has been implicated as a risk factor for several chronic health conditions. Recent studies have reported a relationship between obesity and periodontitis, but few studies have investigated this relationship in adolescents. The purpose of the present study was to investigate the relation...

journal_title：Journal of periodontal research

authors： Ekuni D,Yamamoto T,Koyama R,Tsuneishi M,Naito K,Tobe K

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:A tumor-necrosis factor-alpha (TNF-alpha) antagonist, the WP9QY peptide, was designed based on the crystal structure of the TNF-beta/TNF-receptor complex in order to overcome the disadvantages of macromolecules such as antibodies or soluble receptors by reducing the molecular size of TNF-alpha antagonists. I...

journal_title：Journal of periodontal research

authors： Suzuki Y,Aoki K,Saito H,Umeda M,Nitta H,Baron R,Ohya K

更新日期：2006-04-01 00:00:00

abstract：:Polymorphonuclear neutrophils (PMNs) are essential in host defense against periodontopathic bacteria such as Porphyromonas gingivalis. The uptake of immunoglobulin G (IgG)-opsonized bacteria via IgG Fc receptors (Fc gamma R) on PMN constitutes a central defense mechanism in periodontium. Fc gamma RIIIb is the most abu...

journal_title：Journal of periodontal research

authors： Kobayashi T,van der Pol WL,van de Winkel JG,Hara K,Sugita N,Westerdaal NA,Yoshie H,Horigome T

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Several studies have shown an association between periodontitis and cardiovascular disease (CVD). Atherosclerosis is the major cause of CVD, and a key event in the development of atherosclerosis is accumulation of lipoproteins within the arterial wall. Bacteria are the primary etiologic agents ...

journal_title：Journal of periodontal research

authors： Lönn J,Ljunggren S,Klarström-Engström K,Demirel I,Bengtsson T,Karlsson H

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:Developmental endothelial locus-1 (Del-1), lymphocyte function-associated antigen-1 (LFA-1), and interleukin 17 (IL-17) play critical roles in transendothelial migration of neutrophils in periodontal diseases. The aim of this study was to evaluate salivary Del-1, IL-17, and LFA-1 protein levels...

journal_title：Journal of periodontal research

authors： Inönü E,Kayis SA,Eskan MA,Hakki SS

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Enamel matrix derivative (EMD) is used clinically to promote periodontal tissue regeneration, and it has been reported that EMD can induce the formation of osteoclasts in mouse marrow cultures. In the present study, we investigated the mechanisms of EMD-induced osteoclast formation using a mous...

journal_title：Journal of periodontal research

authors： Itoh N,Kasai H,Ariyoshi W,Harada E,Yokota M,Nishihara T

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interleukin-6 (IL-6) is a key proinflammatory cytokine that has been considered to be important in the pathogenesis of periodontal disease. Therefore, host-modulatory agents directed at inhibiting IL-6 appear to be beneficial in terms of attenuating periodontal disease progression and potential...

journal_title：Journal of periodontal research

authors： Jin JY,Choi EY,Park HR,Choi JI,Choi IS,Kim SJ

更新日期：2013-12-01 00:00:00

abstract：:Portions of clinically healthy non-keratinized and keratinized oral epithelia were removed from adult vervet monkeys (Cercopithecus aethiops). The epithelium was separated from the underlying lamina propria by trypsin digestion, following which the epithelial cells were separated from the various epithelial layers. ...

journal_title：Journal of periodontal research

authors： Cleaton-Jones P

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Parotid secretory protein (PSP) is a major salivary protein that is thought to possess both antibacterial and anti-inflammatory activity. A major question is whether PSP expression can be regulated by humoral factors and bacteria. Periodontitis is an inflammatory lesion initiated by interaction between gingi...

journal_title：Journal of periodontal research

authors： Shiba H,Venkatesh SG,Gorr SU,Barbieri G,Kurihara H,Kinane DF

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Races and Gm(23) allotypes can modify the serum levels of IgG subclasses. The average serum levels of IgG subclasses of African-Americans have been reported to be higher than those of Caucasians in both healthy young adults and patients with aggressive periodontitis; Gm(23)-positive subjects generally had hi...

journal_title：Journal of periodontal research

authors： Chung HY,Lu HC,Chen WL,Lu CT,Yang YH,Tsai CC

更新日期：2003-10-01 00:00:00

abstract：:The distribution of collagen types I and III was demonstrated in healthy periodontal tissues of the rat and marmoset using immunofluorescent localization after decalcification of the maxillae and mandiblae in 0.2 N HCl. An intense fluorescence in the alveolar bone and cementum matrix, as well as in the soft periodonta...

journal_title：Journal of periodontal research

authors： Romanos GE,Schröter-Kermani C,Hinz N,Wachtel HC,Bernimoulin JP

更新日期：1992-03-01 00:00:00

abstract：:The cellular heterogeneity of Malassez epithelium (ME) residing in the periodontal ligament has recently been reported, and the presence and coexistence of the neuropeptides calcitonin gene-related peptide (CGRP), substance P (SP) and vasoactive intestinal peptide (VIP) in single cells in ME has been shown (1). Howeve...

journal_title：Journal of periodontal research

authors： Tadokoro O,Maeda T,Heyeraas KJ,Vandevska-Radunovic V,Kozawa Y,Hals Kvinnsland I

更新日期：2002-12-01 00:00:00

abstract：:Karyometric and cytophotometric measurements of DNA and RNA have been evaluated in gingival graft epithelium. The study was conducted during the first 20 hours from the time of grafting when the graft epithelium undergoes a process of autolysis. Both basal cell and prickle cell layers were used. The results showed an ...

journal_title：Journal of periodontal research

authors： Janson WA,Catanzaro-Gluimaräes SA,Passenezi E

更新日期：1975-02-01 00:00:00

abstract：:It has been estimated that half the annual health care budget in the United States is spent on patients suffering from tissue loss and late stage organ failure. Critical limitations inherent in traditional therapies call for novel tissue and organ replacement strategies. This paper discusses development of biomaterial...

journal_title：Journal of periodontal research

authors： Murphy WL,Mooney DJ

更新日期：1999-10-01 00:00:00

abstract：:Bradykinin stimulated production of prostaglandin E2 (PGE2) and the release of 3H-arachidonic acid by gingival fibroblasts in a time- and dose-dependent manner. The effect on PGE2 biosynthesis was seen already after 15 seconds and was maximal after 5 minutes. Several structurally unrelated inhibitors of arachidonic ac...

journal_title：Journal of periodontal research

authors： Modéer T,Ljunggren O,Lerner UH

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effects of non-surgical periodontal therapy on gingival crevicular fluid levels of matrix metalloproteinase-8 (MMP-8), interleukin-6 (IL-6) and prostaglandin E2 (PGE2 ) in patients with rheumatoid arthritis (RA) with periodontal disease. MATERIAL AND METHODS:Twenty-s...

journal_title：Journal of periodontal research

authors： Kurgan Ş,Fentoğlu Ö,Önder C,Serdar M,Eser F,Tatakis DN,Günhan M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Aggregatibacter actinomycetemcomitans is one of the etiological pathogens implicated in the onset of periodontal disease. This pathogen produces cytolethal distending toxin (CDT) that acts as a genotoxin to induce cell cycle arrest and cellular distension in cultured cell lines. Therefore, CDT is a possible ...

journal_title：Journal of periodontal research

authors： Ohara M,Miyauchi M,Tsuruda K,Takata T,Sugai M

更新日期：2011-06-01 00:00:00

abstract：:Recent reports suggest that specific serum IgG subclasses are a feature of several forms of periodontitis. GCF antibodies are both serum-derived and locally produced by the abundant plasma cells of the diseased periodontal tissue. Previous work has shown that crevicular fluid (GCF) levels of IgG may be reduced in acti...

journal_title：Journal of periodontal research

authors： Kinane DF,Takahashi K,Mooney J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:One of the major pathologic patterns in periodontitis represents an imbalance among the production of free radicals and local antioxidants resulting in periodontal tissue destruction. The objective of the study was to investigate the influence of non-surgical periodontal treatment on salivary a...

journal_title：Journal of periodontal research

authors： Novakovic N,Todorovic T,Rakic M,Milinkovic I,Dozic I,Jankovic S,Aleksic Z,Cakic S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Methylglyoxal is a toxic product derived from glucose metabolism that plays a role in inflammation, diabetes and aging. In addition, the periodontal pathogen Tannerella forsythensis may also generate this compound. However, the effects of methylglyoxal on gingival cells are still poorly unders...

journal_title：Journal of periodontal research

authors： Retamal IN,Hernández R,González-Rivas C,Cáceres M,Arancibia R,Romero A,Martínez C,Tobar N,Martínez J,Smith PC

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:The aim of this immunocytochemical study was to characterize the expression and distribution of the progesterone receptor (PR) and estrogen receptor (ER) in gingival fibroblasts using culture cells derived from people at various ages. BACKGROUND:The reaction of female hormones is tissue or cell specific, and...

journal_title：Journal of periodontal research

authors： Kawahara K,Shimazu A

更新日期：2003-06-01 00:00:00

abstract：:Effects of lathyrogens such as aminoacetonitrile (AAN), beta-aminopropionitrile (BAPN) and cysteamine--known inhibitors of cross-linking of collagen--on the mechanical strength of the periodontal ligament of the rat mandibular first molar were examined by measuring the ultimate load required to extract the tooth from ...

journal_title：Journal of periodontal research

authors： Ohshima S,Nakamura G,Chiba M

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Multiple studies support the role of periodontal disease in contributing to the chronic systemic inflammatory burden in a variety of diseases, including ankylosing spondylitis (AS), in the progression which the inflammatory process plays an important role. We assume that patients with AS are mo...

journal_title：Journal of periodontal research

authors： Sezer U,Erciyas K,Pehlivan Y,Ustün K,Tarakçioğlu M,Senyurt SZ,Onat AM

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Following tooth extraction, bone resorption is especially severe in cases complicated with buccal dehiscence bone defects. To minimize this, various bone graft materials have been used for alveolar ridge preservation. This study aimed to evaluate additional effects of the concomitant use of rec...

journal_title：Journal of periodontal research

authors： Fukuba S,Akizuki T,Matsuura T,Okada M,Nohara K,Hoshi S,Shujaa Addin A,Iwata T,Izumi Y

更新日期：2020-12-12 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Alveolar bone resorption is a characteristic feature of periodontal diseases and involves removal of both the mineral and the organic constituents of the bone matrix, a process mainly carried out by multinucleated osteoclast cells. (-)-Epigallocatechin gallate, the main constituent of green tea...

journal_title：Journal of periodontal research

authors： Yun JH,Kim CS,Cho KS,Chai JK,Kim CK,Choi SH

更新日期：2007-06-01 00:00:00

abstract：:Quantitative assessment of osseous changes attributable to periodontal disease is made possible by digital subtraction radiography. Tissues through which x rays travel to produce dental radiographs essential to this process alter the energy spectrum of the beam such that calibration errors result when densitometry is ...

journal_title：Journal of periodontal research

authors： Webber RL,Tzukert A,Ruttimann U

更新日期：1989-01-01 00:00:00