Crevicular fluid and serum IgG subclasses and corresponding mRNA expressing plasma cells in periodontitis lesions.

abstract：:The present study was carried out to examine the ultrastructural localization of laminin and type-IV collagen in the junctional epithelium of rat molar gingiva by means of the indirect immunoperoxidase method. Intense laminin reaction occurred in both the internal and the external basal laminae. Laminin reaction produ...

journal_title：Journal of periodontal research

authors： Sawada T,Yamamoto T,Yanagisawa T,Takuma S,Hasegawa H,Watanabe K

更新日期：1990-11-01 00:00:00

abstract：:Growth factors are known to play a major role in the regeneration of the periodontium. Basic fibroblast growth factor (bFGF) is a polypeptide growth factor considered to have a role in chemotaxis and mitogenesis of periodontal ligament (PDL) cells. The aim of this study was to assess the effect of bFGF on the transcri...

journal_title：Journal of periodontal research

authors： Palmon A,Roos H,Reichenberg E,Grosskop A,Bar Kana I,Pitaru S,Redlich M

更新日期：2001-04-01 00:00:00

abstract：:Interleukin-1 (IL-1) molecules, IL-1 alpha and IL-1 beta are cytokines involved in the acute-phase response against infection and in the pathogenesis of periodontal destruction. Administration of exogenous IL-1 receptor antagonist (IL-1ra) is effective in reducing the inflammatory reactions mediated by IL-1. However, ...

journal_title：Journal of periodontal research

authors： Ishihara Y,Nishihara T,Kuroyanagi T,Shirozu N,Yamagishi E,Ohguchi M,Koide M,Ueda N,Amano K,Noguchi T

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Probiotics create a biofilm and protect the oral tissues against the action of periodontal pathogenic bacteria. The aim of this study was to evaluate the effects of the oral probiotic Lactobacillus reuteri Prodentis upon the peri-implant health of edentulous patients with dental implants and p...

journal_title：Journal of periodontal research

authors： Flichy-Fernández AJ,Ata-Ali J,Alegre-Domingo T,Candel-Martí E,Ata-Ali F,Palacio JR,Peñarrocha-Diago M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:  The junctional epithelium provides the front-line defense against periodontal bacterial infection. The migration of neutrophils into the junctional epithelium might represent a protective reaction against bacterial infections. However, neutrophils penetrate into the junctional epithelium even...

journal_title：Journal of periodontal research

authors： Tsukamoto Y,Usui M,Yamamoto G,Takagi Y,Tachikawa T,Yamamoto M,Nakamura M

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Periodontitis is an increasingly prevalent complication of diabetes mellitus (known as diabetes mellitus-associated periodontitis), and 25-hydroxyvitamin D3 (25VD3 ) was recently found to be a critical regulator of innate immunity in this disease, but the underlying mechanisms remain poorly und...

journal_title：Journal of periodontal research

authors： Zhang P,Zhang W,Zhang D,Wang M,Aprecio R,Ji N,Mohamed O,Li Y,Ding Y,Wang Q

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Porphyromonas gingivalis lipopolysaccharide (LPS) is a ligand for cell surface toll-like receptors (TLR), TLR2 and TLR4 while stimulation of either leads to cardioprotection. We hypothesized that: (1) pretreatment with P. gingivalis LPS at appropriate concentrations would induce cardioprotectio...

journal_title：Journal of periodontal research

authors： Fan MH,Wong KL,Wu S,Leung WK,Yam WC,Wong TM

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study analyzed the interaction of Porphyromonas gingivalis ATCC 33277 and Aggregatibacter actinomycetemcomitans Y4 with peripheral blood polymorphonuclear neutrophils taken from patients with aggressive periodontitis and chronic periodontitis. MATERIAL AND METHODS:Peripheral blood polymor...

journal_title：Journal of periodontal research

authors： Guentsch A,Puklo M,Preshaw PM,Glockmann E,Pfister W,Potempa J,Eick S

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Fibronectin (FN) is an important cell adhesion molecule that is used widely to characterize cell behavior. Preparations of FN purified from human plasma by gelatin-Sepharose affinity chromatography typically also contain gelatin-binding gelatinases that may cleave FN, reduce its stability and a...

journal_title：Journal of periodontal research

authors： Pal S,Chen Z,Xu X,Mikhailova M,Steffensen B

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Regulation of epithelial cell behavior associated with periodontitis is not well elucidated but many responses will ultimately be regulated by growth factor receptors. Using a rat experimental periodontitis model, protein and gene expression of select growth factor receptors in junctional and p...

journal_title：Journal of periodontal research

authors： Ekuni D,Firth JD,Putnins EE

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVES AND BACKGROUND:Endothelin-1 (ET-1) is a 21-amino acid peptide with multifunctional regulation. ET-1 expresses in various cells during inflammation. The present study aimed to examine the ET-1 expression in oral epithelial cells after infection with the periodontal pathogen and to investigate the presence of ...

journal_title：Journal of periodontal research

authors： Yamamoto E,Awano S,Koseki T,Ansai T,Takehara T

更新日期：2003-08-01 00:00:00

abstract：:The characteristic hemagglutination (HA) of Leptotrichia buccalis was used for measuring its attachment to various human cells and for determining if saliva contained hemagglutination inhibition (HI) factors. The microbial strain utilized displayed the characteristic EM morphology of L. buccalis. Sonicated preparation...

journal_title：Journal of periodontal research

authors： Falkler WA Jr,Hawley CE,Mongiello JR

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Forsythia detaching factor (FDF) is a putative virulence factor of Tannerella forsythia that induces detachment of adherent cells and interleukin-8 production in human fibroblasts. The objective of the present study was to clarify the relationship between anti-FDF IgG levels in gingival crevicu...

journal_title：Journal of periodontal research

authors： Onishi H,Arakawa S,Nakajima T,Izumi Y

更新日期：2010-10-01 00:00:00

abstract：:Interleukin-8 (IL-8) is believed to play an important role in the pathogenesis of various forms of periodontitis. In addition, the anti-IL-8 autoantibody has been recently recognized as a potent modulator of IL-8 function. In the current study, the concentrations of IL-8 and its autoantibody in gingival crevicular flu...

journal_title：Journal of periodontal research

authors： Kurdowska AK,Noble JM,Adcock JE

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Current epidemiological works have suggested that chronic infections, such as periodontitis, are associated with an increased risk of cardiovascular diseases, including hypertrophy and heart failure. However, mechanisms behind the association are not known. The aim of this study was to evaluate...

journal_title：Journal of periodontal research

authors： Köse O,Arabacı T,Gedikli S,Eminoglu DÖ,Kermen E,Kızıldağ A,Kara A,Ozkanlar S,Yemenoglu H

更新日期：2017-04-01 00:00:00

abstract：:Glycosaminoglycans in normal and cyclosporin-induced gingival overgrowth were extracted by papain digestion and purified by Mono Q-FPLC chromatography. The purified glycosaminoglycans were analyzed by agarose gel electrophoresis and by the pattern of degradation products formed by chondroitin lyases on HPLC chromatogr...

journal_title：Journal of periodontal research

authors： Rocha LA,Martins RC,Werneck CC,Feres-Filho EJ,Silva LC

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:To study the expression and role in vigabatrin (VGB)-induced gingival enlargement of Ki-67 antigen and p27KIP1, p21WAF1, and p53, proteins that activate or inhibit cell-cycle progression. MATERIALS AND METHODS:Six patients treated with VGB for partial epileptic seizures refractory to classic anticonvulsant t...

journal_title：Journal of periodontal research

authors： Mesa F,Aguilar M,Gonzalez-Moles MA,Guerrero A,Sanchez-Alvarez JC,Del Moral RG,O'Valle F

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVES:Reactive oxygen species (ROS) are implicated in the destruction of the periodontium during inflammatory periodontal diseases. The imbalance in oxidant/antioxidant activity may be a key factor in the damaging effects of ROS. This study aimed to determine the lipid peroxidation levels in gingival crevicular fl...

journal_title：Journal of periodontal research

authors： Tsai CC,Chen HS,Chen SL,Ho YP,Ho KY,Wu YM,Hung CC

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Neutrophil extracellular traps (NETs) are a recently discovered antimicrobial mechanism used by neutrophils that have been proposed as an intervention in the pathogenesis of periodontitis. The objective of our study was to characterize the expression of NETs in gingival tissues with periodontit...

journal_title：Journal of periodontal research

authors： Magán-Fernández A,O'Valle F,Abadía-Molina F,Muñoz R,Puga-Guil P,Mesa F

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Arecoline, an arecanut alkaloid present in the saliva of betel quid chewers, has been implicated in the pathogenesis of a variety of inflammatory oral diseases, including oral submucous fibrosis and periodontitis. To understand the molecular basis of arecoline action in epithelial changes assoc...

journal_title：Journal of periodontal research

authors： Thangjam GS,Kondaiah P

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Porphyromonas gingivalis has been shown to actively invade endothelial cells and induce vascular cell adhesion molecule 1 (VCAM-1) and intercellular adhesion molecule 1 (ICAM-1) overexpression. Nucleotide-binding oligomerization domain 1 (NOD1) is an intracellular pattern recognition reporter, ...

journal_title：Journal of periodontal research

authors： Wan M,Liu J,Ouyang X

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:beta defensin antimicrobial peptides are important in epithelial innate immunity, and their differential expression is associated with periodontal diseases. The aims of this study were to determine the mRNA expression of human beta defensin-1 and -2 in the gingival tissue of patients with gingi...

journal_title：Journal of periodontal research

authors： Vardar-Sengul S,Demirci T,Sen BH,Erkizan V,Kurulgan E,Baylas H

更新日期：2007-10-01 00:00:00

abstract：:The exact cell type and site(s) involved in interleukin-1 (IL-1) production during gingival inflammation was determined by combining immunohistochemistry and in situ hybridization. IL-1 messenger RNA (mRNA)-expressing cells in human inflamed gingiva were identified as macrophages. The rate of IL-alpha mRNA expression ...

journal_title：Journal of periodontal research

authors： Matsuki Y,Yamamoto T,Hara K

更新日期：1993-01-01 00:00:00

abstract：:To investigate the effect of lipopolysaccharide (LPS) on phagocytic activity of collagen fibrils by periodontal fibroblasts, we studied rat molar gingival connective tissue and periodontal ligament under light and electron microscopy after topical application of LPS (5 mg/ml in physiological salt solution (PS)) on the...

journal_title：Journal of periodontal research

authors： Ijuhin N,Miyauchi M,Ito H,Takata T,Ogawa I,Nikai H

更新日期：1992-05-01 00:00:00

abstract：:Human gingival tissues from periodontitis patients were found to contain from 126 fg/mg to 2161 fg/mg interleukin-1 beta as determined by a sensitive enzyme linked immunoassay. No IL-1 beta could be found in normal gingival tissue. This finding may have important consequences relevant to connective tissue destruction ...

journal_title：Journal of periodontal research

authors： Hönig J,Rordorf-Adam C,Siegmund C,Wiedemann W,Erard F

更新日期：1989-11-01 00:00:00

abstract：:In general, randomized clinical trials (RCT) in dentistry involve longitudinal observations. In such studies, the total cost is a function of the number of study subjects and visits, the study duration, and the type and number of examinations at each visit. In this paper, we derived the minimum cost design for longitu...

journal_title：Journal of periodontal research

authors： Hefti AF,Yang MC

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:This study investigated the oxidative burst function of peripheral phagocytic cells (granulocytes and monocytes) and assessed the relation between oxidative burst and periodontal status in adult individuals with Down syndrome (DS) vs. other groups. METHODS:Of 55 DS individuals (18-56 years old), 74 individu...

journal_title：Journal of periodontal research

authors： Khocht A,Russell B,Cannon JG,Turner B,Janal M

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:After tooth formation is complete, it is suggested that continuity exists between the epithelial cell rests of Malassez (ERM), reduced enamel epithelium (REE) and subsequently the junctional epithelium. However, the junctional epithelium was reported to differ from REE and ERM. The developmenta...

journal_title：Journal of periodontal research

authors： Li S,Ge S,Yang P

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Inducible nitric oxide synthase (iNOS) activity is known to regulate the immune response. The present study was carried out to determine the effect of L-N6-(1-iminoethyl)-lysine (L-NIL), an iNOS inhibitor, on the induction of immune response to Actinobacillus actinomycetemcomitans lipopolysacc...

journal_title：Journal of periodontal research

authors： Sosroseno W,Musa M,Ravichandran M,Fikri Ibrahim M,Bird PS,Seymour GJ

更新日期：2007-04-01 00:00:00

abstract：:Recently, a relationship was demonstrated between the thickness of the cementum layer in rat molars and the activity of alkaline phosphatase (ALP) in the adjoining periodontal ligament (PDL). It was the aim of the present study to investigate whether such a relationship also exists in the periodontium of man. Healthy ...

journal_title：Journal of periodontal research

authors： van den Bos T,Beertsen W

更新日期：1999-01-01 00:00:00