当前位置： SCI文献检索 > JOURNAL OF PERIODONTAL RESEARCH期刊下所有文献 > Levels of specific immunoglobulin G to the forsythia detaching factor of Tannerella forsythia in gingival crevicular fluid are related to the periodontal status.

Levels of specific immunoglobulin G to the forsythia detaching factor of Tannerella forsythia in gingival crevicular fluid are related to the periodontal status.

Abstract：

BACKGROUND AND OBJECTIVE:Forsythia detaching factor (FDF) is a putative virulence factor of Tannerella forsythia that induces detachment of adherent cells and interleukin-8 production in human fibroblasts. The objective of the present study was to clarify the relationship between anti-FDF IgG levels in gingival crevicular fluid and the clinical status in patients with periodontitis and in healthy subjects. MATERIAL AND METHODS:Gingival crevicular fluid and subgingival plaque samples were obtained from both the diseased and healthy sites of 37 patients with periodontitis and from 30 healthy subjects. Anti-FDF IgG levels were evaluated, and both the fdf gene and T. forsythia 16S ribosomal RNA (rRNA) were detected using the PCR. RESULTS:Anti-FDF IgG levels (of both diseased and healthy sites) of patients with periodontitis were significantly higher than those of healthy subjects. Among the patients with periodontitis, anti-FDF IgG levels of healthy sites were significantly higher than those of diseased sites and the levels showed negative correlations with probing pocket depth and clinical attachment level. Among the patients with periodontitis, T. forsythia 16S rRNA was detected in 18 of 37 diseased sites and in 5 of 29 healthy sites, and the fdf gene was detected in 19 of 37 diseased sites and in 7 of 29 healthy sites. By contrast, no healthy subjects were positive for T. forsythia 16S rRNA or the fdf gene. CONCLUSION:These data suggest that anti-FDF IgG levels in gingival crevicular fluid are related to the periodontal status.

journal_name

J Periodontal Res

journal_title

Journal of periodontal research

authors

Onishi H,Arakawa S,Nakajima T,Izumi Y

doi

10.1111/j.1600-0765.2010.01283.x

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

672-80

issue

5

eissn

0022-3484

issn

1600-0765

pii

JRE1283

journal_volume

45

pub_type

杂志文章

相关文献

JOURNAL OF PERIODONTAL RESEARCH文献大全
  • Periodontal tissue regeneration by recombinant human transforming growth factor-beta 3 in Papio ursinus.

    abstract：BACKGROUND AND OBJECTIVE:Osteogenic proteins of the transforming growth factor-beta superfamily induce periodontal tissue regeneration in animal models, including primates. To our knowledge, no studies have been performed in periodontal regeneration using the transforming growth factor-beta 3 isoform. In the present st...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2007.00987.x

    authors： Teare JA,Ramoshebi LN,Ripamonti U

    更新日期：2008-02-01 00:00:00

  • Proteome data set of human gingival crevicular fluid from healthy periodontium sites by multidimensional protein separation and mass spectrometry.

    abstract：BACKGROUND AND OBJECTIVE:Gingival crevicular fluid has been of major interest for many decades as a valuable body fluid that may serve as a source of biomarkers for both periodontal and systemic diseases. Owing to its very small sample size, submicroliter volumes, identification of its protein composition by classical ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2011.01429.x

    authors： Carneiro LG,Venuleo C,Oppenheim FG,Salih E

    更新日期：2012-04-01 00:00:00

  • Lipoprotein modifications by gingipains of Porphyromonas gingivalis.

    abstract：BACKGROUND AND OBJECTIVE:Several studies have shown an association between periodontitis and cardiovascular disease (CVD). Atherosclerosis is the major cause of CVD, and a key event in the development of atherosclerosis is accumulation of lipoproteins within the arterial wall. Bacteria are the primary etiologic agents ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12527

    authors： Lönn J,Ljunggren S,Klarström-Engström K,Demirel I,Bengtsson T,Karlsson H

    更新日期：2018-06-01 00:00:00

  • Simvastatin inhibits lipopolysaccharide-induced osteoclastogenesis and reduces alveolar bone loss in experimental periodontal disease.

    abstract：BACKGROUND AND OBJECTIVE:Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase and have anti-inflammatory effects independent of cholesterol lowering. Recent clinical studies have indicated that statin intake has a beneficial effect on periodontal disease. However, the underlying mechanisms have not...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12132

    authors： Jin J,Zhang X,Lu Z,Li Y,Lopes-Virella MF,Yu H,Haycraft CJ,Li Q,Kirkwood KL,Huang Y

    更新日期：2014-08-01 00:00:00

  • Comparison of treatment effects of guided tissue regeneration on infrabony lesions between animal and human studies: a systematic review and meta-analysis.

    abstract：BACKGROUND AND OBJECTIVE:For ethical reasons it is becoming increasingly more difficult to obtain, from clinical studies, histological data on infrabony defects treated with guided tissue regeneration (GTR) techniques. The aim of this systematic review was to find the value of extrapolating animal data on treatment of ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章,meta分析,评审

    doi：10.1111/jre.12130

    authors： Yen CC,Tu YK,Chen TH,Lu HK

    更新日期：2014-08-01 00:00:00

  • Quantifying oral inflammatory load: oral neutrophil counts in periodontal health and disease.

    abstract：BACKGROUND AND OBJECTIVE:Neutrophils are the primary white blood cells that are recruited to fight the initial phases of microbial infections. While healthy norms have been determined for circulating blood neutrophil counts in order to identify patients with suspected systemic infections, the levels of oral neutrophils...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12211

    authors： Landzberg M,Doering H,Aboodi GM,Tenenbaum HC,Glogauer M

    更新日期：2015-06-01 00:00:00

  • Analysis of interleukin-1beta-modulated mRNA gene transcription in human gingival keratinocytes by epithelia-specific cDNA microarrays.

    abstract：BACKGROUND/OBJECTIVES:Proinflammatory cytokines such as interleukin-1beta are known to be synthesized in oral gingivitis and periodontitis and lead to the activation of the transcription factor nuclear factor-kappaB (NF-kappaB). Although numerous effects of interleukin-1beta on mesenchymal cells are known, e.g. up-regu...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2006.00884.x

    authors： Steinberg T,Dannewitz B,Tomakidi P,Hoheisel JD,Müssig E,Kohl A,Nees M

    更新日期：2006-10-01 00:00:00

  • MiR-153-3p inhibits osteogenic differentiation of periodontal ligament stem cells through KDM6A-induced demethylation of H3K27me3.

    abstract：BACKGROUND AND OBJECTIVE:Periodontal ligament stem cells (PDLSCs) have potential for osteogenic differentiation and show a great foreground in treating bone diseases. Histone three lysine 27 (H3K27) demethylase lysine demethylase 6A (KDM6A) is a critical epigenetic modifier and plays an important role in regulating ost...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12830

    authors： Jiang H,Jia P

    更新日期：2020-12-24 00:00:00

  • Decreased expression of E-cadherin by Porphyromonas gingivalis-lipopolysaccharide attenuates epithelial barrier function.

    abstract：BACKGROUND AND OBJECTIVE:The gingival epithelium is a first line of defense against bacterial challenge. E-cadherin (E-cad) plays an important role in cell-cell adhesion as a barrier in the epithelium. Recently, a decrease in the expression of E-cad has been observed in inflamed gingival tissue. The aims of this study ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12367

    authors： Abe-Yutori M,Chikazawa T,Shibasaki K,Murakami S

    更新日期：2017-02-01 00:00:00

  • Patterns of cytokeratin expression in monkey and human periodontium following regenerative and conventional periodontal surgery.

    abstract：:The pattern of cytokeratin expression has been extensively described in the normal and inflamed periodontium. However, there is no information regarding the pattern of cytokeratin expression in the periodontium which has been reformed following regenerative periodontal surgery. The aim of the present investigation was...

    journal_title：Journal of periodontal research

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1034/j.1600-0765.2001.036004260.x

    authors： Sculean A,Berakdar M,Pahl S,Windisch P,Brecx M,Reich E,Donos N

    更新日期：2001-08-01 00:00:00

  • Increased titre and avidity of IgG antibodies to Porphyromonas gingivalis whole cells and a cell surface protein in subjects with adult periodontitis.

    abstract：:The titre and avidity of IgG antibodies to Porphyromonas gingivalis whole cells and a 47 kDa cell surface protein were determined in serum samples taken from 20 subjects with adult periodontitis and 20 controls, matched for age, gender, ethnic origin and oral hygiene status. Antibody titres were measured by ELISA and ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1997.tb01379.x

    authors： Benjamin PA,Rogers PA,U S,Johnson NW,Cole MF,Curtis MA

    更新日期：1997-01-01 00:00:00

  • Alkaline phosphatase activity in human periodontal ligament: age effect and relation to cementum growth rate.

    abstract：:Recently, a relationship was demonstrated between the thickness of the cementum layer in rat molars and the activity of alkaline phosphatase (ALP) in the adjoining periodontal ligament (PDL). It was the aim of the present study to investigate whether such a relationship also exists in the periodontium of man. Healthy ...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1999.tb02215.x

    authors： van den Bos T,Beertsen W

    更新日期：1999-01-01 00:00:00

  • Retinoic acid is a potential negative regulator for differentiation of human periodontal ligament cells.

    abstract：BACKGROUND AND OBJECTIVES:Retinoic acid (RA) exerts a wide variety of effects on development, cellular differentiation and homeostasis in various tissues. However, little is known about the effects of RA on the differentiation of periodontal ligament cells. In this study, we investigated whether RA can affect the dexam...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2005.00811.x

    authors： Shibuya N,Nemoto E,Kanaya S,Kunii R,Shimauchi H

    更新日期：2005-12-01 00:00:00

  • Povidone-iodine as a periodontal pocket disinfectant.

    abstract：OBJECTIVES AND BACKGROUND:Povidone-iodine [polyvinylpyrrolidone-iodine complex (PVP-iodine)] might constitute a valuable adjunct to current periodontal therapy because of its broad-spectrum antimicrobial activity, low potential for developing resistance and adverse reactions, wide availability, ease of use, and low fin...

    journal_title：Journal of periodontal research

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1034/j.1600-0765.2003.02016.x

    authors： Hoang T,Jorgensen MG,Keim RG,Pattison AM,Slots J

    更新日期：2003-06-01 00:00:00

  • Expression of TIMP-1, TIMP-2 and collagenase mRNA in periodontitis-affected human gingival tissue.

    abstract：:Collagenolysis in periodontitis is thought to be modulated by the expression of three genes, collagenase, tissue inhibitors of metalloproteinases-1 and -2 (TIMP-1 and -2). We assessed the possible difference in TIMP-1, TIMP-2 and collagenase mRNA levels between gingival samples from patients with periodontitis and tho...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1993.tb01079.x

    authors： Nomura T,Takahashi T,Hara K

    更新日期：1993-09-01 00:00:00

  • Nicotine inhibits osteogenic differentiation of human periodontal ligament cells under cyclic tensile stress through canonical Wnt pathway and α7 nicotinic acetylcholine receptor.

    abstract：BACKGROUND AND OBJECTIVES:Nicotine, the main psychoactive component of tobacco, affects cell metabolism, proliferation, adhesion and, importantly, the osteogenic differentiation of fibroblasts. Approximately 15% of all orthodontic patients are adults among who one-fifth are smokers. Hence, it is necessary to have insig...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12545

    authors： Yu W,Hu B,Shi X,Cao Z,Ren M,He Z,Lin J,Deng H,Hu R

    更新日期：2018-08-01 00:00:00

  • Alendronate regulates cytokine production induced by lipid A through nuclear factor-κB and Smad3 activation in human gingival fibroblasts.

    abstract：BACKGROUND AND OBJECTIVE:Nitrogen-containing bisphosphonates (NBPs) are widely used as anti-bone-resorptive drugs. However, use of NBPs results in inflammatory side-effects, including jaw osteomyelitis. In the present study, we examined the effects of alendronate, a typical NBP, on cytokine production by human peripher...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2010.01302.x

    authors： Tamai R,Sugiyama A,Kiyoura Y

    更新日期：2011-02-01 00:00:00

  • Predominant immunoreactivity of Porphyromonas gingivalis heat shock protein in autoimmune diseases.

    abstract：BACKGROUND AND OBJECTIVE:Autoimmune diseases, including atherosclerosis, diabetes mellitus and rheumatoid arthritis, can be triggered and aggravated by the pathogen-driven antigenic peptide from Porphyromonas gingivalis HSP60. P. gingivalis is the major pathogen of chronic periodontitis, which is a global epidemic prev...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2012.01501.x

    authors： Jeong E,Lee JY,Kim SJ,Choi J

    更新日期：2012-12-01 00:00:00

  • Increased levels of interleukin-32 isoforms alpha, beta, gamma, and delta in the gingival crevicular fluid and plasma of the patients with periodontitis.

    abstract：BACKGROUND AND OBJECTIVE:Interleukin (IL)-32, which has been recently reported to be associated with periodontitis, has been suggested to have pleiotropic effect due to its 9 different isoforms. The aim of this study was to investigate the levels of IL-32α, IL-32β, IL-32γ, IL-32δ isoforms in gingival crevicular fluid (...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12796

    authors： Öngöz Dede F,Gökmenoğlu C,Deveci ET,Çelen S,Avci B,Kara C,Çanakçi V

    更新日期：2021-01-01 00:00:00

  • Simvastatin therapy in cyclosporine A-induced alveolar bone loss in rats.

    abstract：BACKGROUND AND OBJECTIVE:Cyclosporine A treatment is important in the therapy of a number of medical conditions; however, alveolar bone loss is an important negative side-effect of this drug. As such, we evaluated whether concomitant administration of simvastatin would minimize cyclosporine A-associated alveolar bone l...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2008.01143.x

    authors： Nassar PO,Nassar CA,Guimarães MR,Aquino SG,Andia DC,Muscara MN,Spolidorio DM,Rossa C Jr,Spolidorio LC

    更新日期：2009-08-01 00:00:00

  • Significance of elevated gingival crevicular fluid tumor necrosis factor-alpha and interleukin-8 levels in chronic hemodialysis patients with periodontal disease.

    abstract：BACKGROUND AND OBJECTIVE:The prevalence of chronic renal disease in industrialized countries is increasing, and chronic renal disease and periodontitis can have significant, reciprocal effects. The aim of this study was to evaluate the associations between specific clinical parameters and the levels of tumor necrosis f...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2009.01252.x

    authors： Dağ A,Firat ET,Kadiroğlu AK,Kale E,Yilmaz ME

    更新日期：2010-08-01 00:00:00

  • Clinical, microbiological and immunological profile of healthy, gingivitis and putative active periodontal subjects.

    abstract：:Thirteen periodontally healthy subjects were monitored clinically for 6-12 months. Clinical measurements at 6-weekly intervals included duplicate PD measurements, presence of plaque, redness, and bleeding on probing. Baseline measurements consisted of 2 visits 1 wk apart. Microbial samples were taken from 11 of the su...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1996.tb00484.x

    authors： Tanner A,Kent R,Maiden MF,Taubman MA

    更新日期：1996-04-01 00:00:00

  • ROCK inhibitor Y-27632 maintains the proliferation of confluent human mesenchymal stem cells.

    abstract：BACKGROUND AND OBJECTIVE:The transplantation of cell sheets of mesenchymal stem cells (MSCs) is expected to be the next generation of periodontal regenerative therapy. An adequate method of multilayering MSCs has yet to be established. When cell sheets proliferate, they usually contract and detach from culture dishes a...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12114

    authors： Nakamura K,Yoshimura A,Kaneko T,Sato K,Hara Y

    更新日期：2014-06-01 00:00:00

  • Endothelial cell leukocyte adhesion molecule-1 (ELAM-1) and intercellular adhesion molecule-1 (ICAM-1) expression in gingival tissue during health and experimentally-induced gingivitis.

    abstract：:The changes in vascular adhesion molecule expression and numbers of infiltrating leukocytes during a 21-day experimental gingivitis episode were investigated immunohistochemically. Monoclonal antibodies to ELAM-1 (1.2B6), ICAM-1 (6.5B5), CD3 (OKT3-pan-T cell) and neutrophils (PMN-elastase) were used to identify positi...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1992.tb01746.x

    authors： Moughal NA,Adonogianaki E,Thornhill MH,Kinane DF

    更新日期：1992-11-01 00:00:00

  • Expression and intracellular localization of progesterone receptors in cultured human gingival fibroblasts.

    abstract：OBJECTIVE:The aim of this immunocytochemical study was to characterize the expression and distribution of the progesterone receptor (PR) and estrogen receptor (ER) in gingival fibroblasts using culture cells derived from people at various ages. BACKGROUND:The reaction of female hormones is tissue or cell specific, and...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0765.2003.00654.x

    authors： Kawahara K,Shimazu A

    更新日期：2003-06-01 00:00:00

  • Autoimmunity to collagen in adult periodontal disease: immunoglobulin classes in sera and tissue.

    abstract：:The immunoglobulin class distribution of antibody to human collagen type I has been examined in sera and gingival extracts from patients with adult chronic periodontitis. Tissue extracts were made either by simple washing or ultrasonication. With either method, IgG and IgA antibodies to collagen were present in higher...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.1992.tb02086.x

    authors： Anusaksathien O,Singh G,Matthews N,Dolby AE

    更新日期：1992-01-01 00:00:00

  • Tensile strength, histological and immunohistochemical observations of periodontal wound healing in the dog.

    abstract：:This study was designed to study wound strength at the dentine/connective tissue interface and at the bone/connective tissue interface following full thickness flap surgery. Flaps of uniform dimension were outlined in four young adult beagle dogs using a standardised double bladed knife and vertical incisions 10 mm ap...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0765.2002.01375.x

    authors： Werfully S,Areibi G,Toner M,Bergquist J,Walker J,Renvert S,Claffey N

    更新日期：2002-10-01 00:00:00

  • Inhibitory effects of green tea polyphenol (-)-epigallocatechin gallate on the expression of matrix metalloproteinase-9 and on the formation of osteoclasts.

    abstract：BACKGROUND:Alveolar bone resorption is a characteristic feature of periodontal diseases and involves the removal of both the mineral and organic constituents of the bone matrix, which is caused by either multinucleated osteoclast cells or matrix metalloproteinases (MMPs). The gram-negative bacterium, Porphyromonas ging...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2004.00743.x

    authors： Yun JH,Pang EK,Kim CS,Yoo YJ,Cho KS,Chai JK,Kim CK,Choi SH

    更新日期：2004-10-01 00:00:00

  • An orally administered oral pathobiont and commensal have comparable and innocuous systemic effects in germ-free mice.

    abstract：BACKGROUND AND OBJECTIVES:We recently proposed a novel mechanism linking periodontitis and systemic diseases, in which orally administered Porphyromonas gingivalis affects gut microbiota composition and subsequently leads to systemic inflammation. However, the mechanism by which P. gingivalis generates systemic effects...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/jre.12593

    authors： Sato K,Yokoji M,Yamada M,Nakajima T,Yamazaki K

    更新日期：2018-12-01 00:00:00

  • Diabetes in the dental office: using NHANES III to estimate the probability of undiagnosed disease.

    abstract：BACKGROUND AND OBJECTIVE:Recent data have suggested that in the past 15 years there has been a dramatic increase in the incidence of diabetes mellitus in the USA. However, evidence suggests that approximately one-third of diabetes cases remain undiagnosed. Because 60% of Americans see a dentist at least once per year f...

    journal_title：Journal of periodontal research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0765.2007.00983.x

    authors： Borrell LN,Kunzel C,Lamster I,Lalla E

    更新日期：2007-12-01 00:00:00