Increased levels of interleukin-32 isoforms alpha, beta, gamma, and delta in the gingival crevicular fluid and plasma of the patients with periodontitis.

abstract：:The titre and avidity of IgG antibodies to Porphyromonas gingivalis whole cells and a 47 kDa cell surface protein were determined in serum samples taken from 20 subjects with adult periodontitis and 20 controls, matched for age, gender, ethnic origin and oral hygiene status. Antibody titres were measured by ELISA and ...

journal_title：Journal of periodontal research

authors： Benjamin PA,Rogers PA,U S,Johnson NW,Cole MF,Curtis MA

更新日期：1997-01-01 00:00:00

abstract：:Neuropeptides, including substance P (SP) may play a role in neurogenic inflammation. Although SP-immunoreactive (SP-IR) axons are known to be present within the oral mucosa (OM) and salivary glands, the functional significance of SP in oral mucosa and sublingual salivary gland (SLG) is not fully understood. The prese...

journal_title：Journal of periodontal research

authors： Györfi A,Fazekas A,Irmes F,Rosivall L

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The jaw bone, unlike most other bones, is derived from neural crest stem cells, so we hypothesized that it may have different characteristics to bones from other parts of the body, especially in the nature of its periosteum. The periosteum exhibits osteogenic potential and has received consider...

journal_title：Journal of periodontal research

authors： Ichikawa Y,Watahiki J,Nampo T,Nose K,Yamamoto G,Irie T,Mishima K,Maki K

更新日期：2015-08-01 00:00:00

abstract：:The diagnosis of periodontal disease is commonly based on objective evaluations of the patient's medical/dental history as well as clinical and radiographic examinations. However, periodontal disease should also be evaluated subjectively through measures that quantify its impact on oral health-related quality of life....

journal_title：Journal of periodontal research

authors： Ferreira MC,Dias-Pereira AC,Branco-de-Almeida LS,Martins CC,Paiva SM

更新日期：2017-08-01 00:00:00

abstract：:E-selectin is a cytokine-inducible endothelial glycoprotein which participates in the binding of leukocytes to vascular endothelium. Variable levels of expression of E-selectin have been reported in gingivitis and periodontitis, and two differing concepts of its significance have emerged: either gingival blood vessels...

journal_title：Journal of periodontal research

authors： Pietrzak ER,Savage NW,Xu LJ,Walsh LJ

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Enamel matrix derivative (EMD), extracted from porcine tooth buds, has been shown to promote periodontal healing in patients with severe periodontitis. This involves modulation of the inflammatory response followed by the onset of periodontal regeneration. Based on these observations, we examin...

journal_title：Journal of periodontal research

authors： Myhre AE,Lyngstadaas SP,Dahle MK,Stuestøl JF,Foster SJ,Thiemermann C,Lilleaasen P,Wang JE,Aasen AO

更新日期：2006-06-01 00:00:00

abstract：:The aim of this study was to compare the percentage of vital microorganisms (= microbial vitality) of saliva with that of supragingival plaque both collected at various times during the early phases of de novo plaque formation. Between intervals of optimal oral hygiene, 14 healthy participants refrained from all oral ...

journal_title：Journal of periodontal research

authors： Weiger R,von Ohle C,Decker E,Axmann-Krcmar D,Netuschil L

更新日期：1997-02-01 00:00:00

abstract：:Colonization or emergence of microbial pathogens may result in tissue destruction by activation of one or more of five distinct host degradative pathways (matrix metalloproteinase pathway, plasminogen-dependent pathway, phagocytic pathway, PMN-serine proteinase pathway and osteoclastic bone resorption) or by direct cl...

journal_title：Journal of periodontal research

authors： Birkedal-Hansen H

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:The responsiveness of the sympathetic nervous system (SNS) and the hypothalamic--pituitary--adrenal (HPA) axis plays a major role in immune regulation and for the outcome of infections and inflammatory disorders. This study was designed to investigate whether chemical SNS denervation with the noradrenaline-se...

journal_title：Journal of periodontal research

authors： Breivik T,Gundersen Y,Opstad PK,Fonnum F

更新日期：2005-08-01 00:00:00

abstract：:The effectiveness of an ideal antimicrobial agent depends on its ability to kill microbes with minimal toxicity to host cells. Depending on the treatment regimen, antimicrobial agents come into contact with host cells for various intervals of time. Sanguinarium (SANG), chlorhexidine (CHX) and tetracycline (TET) are 3 ...

journal_title：Journal of periodontal research

authors： Agarwal S,Piesco NP,Peterson DE,Charon J,Suzuki JB,Godowski KC,Southard GL

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Ciclosporin A (CsA)-induced gingival overgrowth is attributed to an exaggerated accumulation of extracellular matrix, which is mainly due to an increased expression of transforming growth factor-β1 (TGF-β1). Herein, the in vitro investigation of effects of overexpression of Smad7, a TGF-β1 sign...

journal_title：Journal of periodontal research

authors： Sobral LM,Aseredo F,Agostini M,Bufalino A,Pereira MC,Graner E,Coletta RD

更新日期：2012-04-01 00:00:00

abstract：:Fibroblast function in gingival tissue is thought to be regulated by the local cellular environment--both the extracellular matrix and soluble factors. In an attempt to artificially re-create this situation fibroblasts have been cultured within 3-dimensional collagen gels in an environment more physiologically compara...

journal_title：Journal of periodontal research

authors： Irwin CR,Schor SL,Ferguson MW

更新日期：1994-09-01 00:00:00

abstract：:An epidemiological association between periodontitis and cardiovascular disease has been reported in multiple studies. Various mechanisms have been proposed as potential explanations for this association, including a common factor that predisposes certain individuals to a hyper-responsive inflammatory response. Variat...

journal_title：Journal of periodontal research

authors： Kornman KS,Pankow J,Offenbacher S,Beck J,di Giovine F,Duff GW

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Membrane type 1-matrix metalloproteinase (MT1-MMP) is a collagenolytic enzyme involved in connective tissue remodeling. In periodontal tissues, either cytokines or growth factors regulate the production of proteolytic enzymes. Mice deficient in epidermal growth factor receptor (EGFR) show a re...

journal_title：Journal of periodontal research

authors： Smith PC,Guerrero J,Tobar N,Cáceres M,González MJ,Martínez J

更新日期：2009-02-01 00:00:00

abstract：:Recently, a relationship was demonstrated between the thickness of the cementum layer in rat molars and the activity of alkaline phosphatase (ALP) in the adjoining periodontal ligament (PDL). It was the aim of the present study to investigate whether such a relationship also exists in the periodontium of man. Healthy ...

journal_title：Journal of periodontal research

authors： van den Bos T,Beertsen W

更新日期：1999-01-01 00:00:00

abstract：:Polymorphonuclear neutrophils (PMNs) are essential in host defense against periodontopathic bacteria such as Porphyromonas gingivalis. The uptake of immunoglobulin G (IgG)-opsonized bacteria via IgG Fc receptors (Fc gamma R) on PMN constitutes a central defense mechanism in periodontium. Fc gamma RIIIb is the most abu...

journal_title：Journal of periodontal research

authors： Kobayashi T,van der Pol WL,van de Winkel JG,Hara K,Sugita N,Westerdaal NA,Yoshie H,Horigome T

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Adipocyte fatty acid-binding protein (A-FABP) is expressed in adipocytes, macrophages and microvascular endothelial cells, and it plays a central role in inflammation, atherosclerosis and metabolic responses. This pilot study investigated the effect of nonsurgical periodontal therapy on the ser...

journal_title：Journal of periodontal research

authors： Li X,Tse HF,Yiu KH,Zhang C,Jin LJ

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The association between psychosocial factors and periodontal disease has been widely reported and might be modified by smoking status. This study investigated the association of periodontal status with psychosocial factors and smoking in a community population. MATERIAL AND METHODS:A structure...

journal_title：Journal of periodontal research

authors： Chiou LJ,Yang YH,Hung HC,Tsai CC,Shieh TY,Wu YM,Wang WC,Hsu TC

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To study the expression and role in vigabatrin (VGB)-induced gingival enlargement of Ki-67 antigen and p27KIP1, p21WAF1, and p53, proteins that activate or inhibit cell-cycle progression. MATERIALS AND METHODS:Six patients treated with VGB for partial epileptic seizures refractory to classic anticonvulsant t...

journal_title：Journal of periodontal research

authors： Mesa F,Aguilar M,Gonzalez-Moles MA,Guerrero A,Sanchez-Alvarez JC,Del Moral RG,O'Valle F

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Few studies estimated the joint effect of implant design (length and diameter), peri-implant, and occlusal variables on early marginal bone loss. The monitoring of these factors during the first year after implant loading may be effective in preventing early implant failure. This prospective lo...

journal_title：Journal of periodontal research

authors： Radaelli MTB,Federizzi L,Nascimento GG,Leite FRM,Boscato N

更新日期：2020-04-01 00:00:00

abstract：AIM:This subgroup analysis of a 12-week randomized, double-blind, and two-center trial aimed to evaluate whether two different toothpaste formulations can differentially modulate the dental microbiome. MATERIAL AND METHODS:Forty one mild to moderate periodontitis patients used as an adjunct to periodontal treatment ei...

journal_title：Journal of periodontal research

authors： Hagenfeld D,Prior K,Harks I,Jockel-Schneider Y,May TW,Harmsen D,Schlagenhauf U,Ehmke B

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The purpose of this in vitro investigation was to study the effects of human cytomegalovirus infection on the mRNA expression for collagens I and III and for matrix metalloproteinases 1 and 2 in gingival fibroblasts. MATERIAL AND METHODS:Gingival fibroblasts were experimentally infected with t...

journal_title：Journal of periodontal research

authors： Botero JE,Contreras A,Parra B

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:It has been suggested that aggressive periodontitis has a genetic basis. Monocyte chemoattractant protein 1 (MCP-1) plays a critical role in the recruitment of monocytes and the development of periodontitis. The -2518MCP-1(A/G) polymorphism has been implicated as a risk or susceptibility factor...

journal_title：Journal of periodontal research

authors： Zhu XL,Meng HX,Zhang L,Xu L,Chen ZB,Shi D,Feng XH,Zhang X

更新日期：2012-06-01 00:00:00

abstract：:The changes in vascular adhesion molecule expression and numbers of infiltrating leukocytes during a 21-day experimental gingivitis episode were investigated immunohistochemically. Monoclonal antibodies to ELAM-1 (1.2B6), ICAM-1 (6.5B5), CD3 (OKT3-pan-T cell) and neutrophils (PMN-elastase) were used to identify positi...

journal_title：Journal of periodontal research

authors： Moughal NA,Adonogianaki E,Thornhill MH,Kinane DF

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Aggregatibacter actinomycetemcomitans is one of the etiological pathogens implicated in the onset of periodontal disease. This pathogen produces cytolethal distending toxin (CDT) that acts as a genotoxin to induce cell cycle arrest and cellular distension in cultured cell lines. Therefore, CDT is a possible ...

journal_title：Journal of periodontal research

authors： Ohara M,Miyauchi M,Tsuruda K,Takata T,Sugai M

更新日期：2011-06-01 00:00:00

abstract：:The 3 human salivary cystatins S, SA and SN are multifunctional proteins that possess a cysteine protease inhibitory property, but their ability to act as such is very different (SN > SA > S). One form, S, also appears to possess antibacterial properties towards the bacterium Porphyromonas gingivalis, often associated...

journal_title：Journal of periodontal research

authors： Baron AC,Gansky SA,Ryder MI,Featherstone JD

更新日期：1999-11-01 00:00:00

abstract：:A single-blind investigation was designed to study the effects of piroxicam in preventing gingival inflammation and plaque formation in beagle dogs. Twelve 1-year-old beagles were brought to optimum oral hygiene and gingival health. Thereafter, they were fed a moist plaque-promoting diet and were divided into three gr...

journal_title：Journal of periodontal research

authors： Howell TH,Fiorellini J,Weber HP,Williams RC

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Long-term tooth retention is the ultimate goal of periodontal therapy. Aim of this study was to evaluate tooth loss (TL) during 10 years of supportive periodontal therapy (SPT) in periodontal compromised patients and to identify factors influencing TL on patient level. MATERIAL AND METHODS:Pat...

journal_title：Journal of periodontal research

authors： Petsos H,Schacher B,Ramich T,Nickles K,Dannewitz B,Arendt S,Seidel K,Eickholz P

更新日期：2020-12-01 00:00:00

abstract：:We have reported recently that increased expression of membrane alkaline phosphatase (ALP) activity is a phenotypical characteristic of gingival fibroblasts located in chronic inflammatory periodontal lesions. To understand the cellular properties of these cells, we isolated ALP-positive gingival fibroblasts from pati...

journal_title：Journal of periodontal research

authors： Abe T,Hara Y,Abe Y,Aida Y,Maeda K

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Several studies have shown an association between periodontitis and cardiovascular disease (CVD). Atherosclerosis is the major cause of CVD, and a key event in the development of atherosclerosis is accumulation of lipoproteins within the arterial wall. Bacteria are the primary etiologic agents ...

journal_title：Journal of periodontal research

authors： Lönn J,Ljunggren S,Klarström-Engström K,Demirel I,Bengtsson T,Karlsson H

更新日期：2018-06-01 00:00:00