Localization of interleukin-1 (IL-1) mRNA-expressing macrophages in human inflamed gingiva and IL-1 activity in gingival crevicular fluid.

abstract：:Volume and amounts of myeloperoxidase (MPO), lactoferrin (LF), aryl sulfatase (AS) and lactate dehydrogenase (LDH) were measured in gingival crevicular fluid (GCF) collected from the mesial and distal proximal surfaces of the premolars and first and second molars of 3 subject groups. Group assignment was based on subj...

journal_title：Journal of periodontal research

authors： Smith QT,Au GS,Freese PL,Osborn JB,Stoltenberg JL

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Methylglyoxal is a toxic product derived from glucose metabolism that plays a role in inflammation, diabetes and aging. In addition, the periodontal pathogen Tannerella forsythensis may also generate this compound. However, the effects of methylglyoxal on gingival cells are still poorly unders...

journal_title：Journal of periodontal research

authors： Retamal IN,Hernández R,González-Rivas C,Cáceres M,Arancibia R,Romero A,Martínez C,Tobar N,Martínez J,Smith PC

更新日期：2016-12-01 00:00:00

abstract：:Using an agar-skim milk gel method, over 300 oral bacterial isolates were tested for their ability to produce trypsin or chymotrypsin inhibitor. Eleven bacterial strains, including seven isolates identified as Bacteroides intermedius, were found to inhibit both proteolytic activities. The inhibitory factors of the 11 ...

journal_title：Journal of periodontal research

authors： Grenier D

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Few studies estimated the joint effect of implant design (length and diameter), peri-implant, and occlusal variables on early marginal bone loss. The monitoring of these factors during the first year after implant loading may be effective in preventing early implant failure. This prospective lo...

journal_title：Journal of periodontal research

authors： Radaelli MTB,Federizzi L,Nascimento GG,Leite FRM,Boscato N

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The potential of salivary microorganisms to diagnose periodontal disease and to guide periodontal treatment is a research topic of current interest. This study aimed to determine whether the salivary counts of periodontopathic microbes correlated with the periodontal pocket counts of the same ...

journal_title：Journal of periodontal research

authors： Saygun I,Nizam N,Keskiner I,Bal V,Kubar A,Açıkel C,Serdar M,Slots J

更新日期：2011-04-01 00:00:00

abstract：:To investigate the effect of lipopolysaccharide (LPS) on phagocytic activity of collagen fibrils by periodontal fibroblasts, we studied rat molar gingival connective tissue and periodontal ligament under light and electron microscopy after topical application of LPS (5 mg/ml in physiological salt solution (PS)) on the...

journal_title：Journal of periodontal research

authors： Ijuhin N,Miyauchi M,Ito H,Takata T,Ogawa I,Nikai H

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effects of non-surgical periodontal therapy on gingival crevicular fluid levels of matrix metalloproteinase-8 (MMP-8), interleukin-6 (IL-6) and prostaglandin E2 (PGE2 ) in patients with rheumatoid arthritis (RA) with periodontal disease. MATERIAL AND METHODS:Twenty-s...

journal_title：Journal of periodontal research

authors： Kurgan Ş,Fentoğlu Ö,Önder C,Serdar M,Eser F,Tatakis DN,Günhan M

更新日期：2016-10-01 00:00:00

abstract：:Diploid fibroblasts obtained from explants of human gingiva and maintained in vitro undergo a several-fold decrease in protein and collagen synthesis as a function of increasing donor age. Using drug-induced gingival hyperplasia as a model, we performed experiments to learn whether fibroblasts derived from hyperplasti...

journal_title：Journal of periodontal research

authors： Johnson BD,Narayanan AS,Pieters HP,Page RC

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:PTH plays an important role in bone remodeling, and different actions have been reported depending on its administration method. iPSCs are promising as a cell source for regeneration of periodontal tissue due to their ability of proliferation and pluripotency. However, the effects of PTH on iPSCs ...

journal_title：Journal of periodontal research

authors： Sato M,Aoki H,Nakamura T,Onodera S,Yamaguchi A,Saito A,Azuma T

更新日期：2020-10-01 00:00:00

abstract：:The present study was carried out to examine the ultrastructural localization of laminin and type-IV collagen in the junctional epithelium of rat molar gingiva by means of the indirect immunoperoxidase method. Intense laminin reaction occurred in both the internal and the external basal laminae. Laminin reaction produ...

journal_title：Journal of periodontal research

authors： Sawada T,Yamamoto T,Yanagisawa T,Takuma S,Hasegawa H,Watanabe K

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Alveolar bone resorption is a characteristic feature of periodontal diseases and involves the removal of both the mineral and organic constituents of the bone matrix, which is caused by either multinucleated osteoclast cells or matrix metalloproteinases (MMPs). The gram-negative bacterium, Porphyromonas ging...

journal_title：Journal of periodontal research

authors： Yun JH,Pang EK,Kim CS,Yoo YJ,Cho KS,Chai JK,Kim CK,Choi SH

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase and have anti-inflammatory effects independent of cholesterol lowering. Recent clinical studies have indicated that statin intake has a beneficial effect on periodontal disease. However, the underlying mechanisms have not...

journal_title：Journal of periodontal research

authors： Jin J,Zhang X,Lu Z,Li Y,Lopes-Virella MF,Yu H,Haycraft CJ,Li Q,Kirkwood KL,Huang Y

更新日期：2014-08-01 00:00:00

abstract：:Epidermal growth factor (EGF) is a small molecular weight polypeptide which is thought to have important functions in epithelial growth and differentiation and in wound healing. EGF exerts its action on cells through binding to a cell surface receptor. Using immunohistochemistry and a monoclonal antibody (mAb) directe...

journal_title：Journal of periodontal research

authors： Nordlund L,Hormia M,Saxén L,Thesleff I

更新日期：1991-07-01 00:00:00

abstract：:Prevotella intermedia has recently been re-defined and a new species, Prevotella nigrescens has been proposed. However, there is little data available on the incidence of these new species in periodontal health or disease. Black-pigmented anaerobes isolated from diseased and healthy subgingival sites were identified b...

journal_title：Journal of periodontal research

authors： Teanpaisan R,Douglas CW,Walsh TF

更新日期：1995-07-01 00:00:00

abstract：AIM:This subgroup analysis of a 12-week randomized, double-blind, and two-center trial aimed to evaluate whether two different toothpaste formulations can differentially modulate the dental microbiome. MATERIAL AND METHODS:Forty one mild to moderate periodontitis patients used as an adjunct to periodontal treatment ei...

journal_title：Journal of periodontal research

authors： Hagenfeld D,Prior K,Harks I,Jockel-Schneider Y,May TW,Harmsen D,Schlagenhauf U,Ehmke B

更新日期：2019-08-01 00:00:00

abstract：:The goal of a single step therapy has been an important consideration in the development of guided tissue regeneration devices. It would spare the patient from the need for repeated surgery and eliminate many problems associated with a non-resorbable barrier. Animal studies of a collagen membrane extracted from porcin...

journal_title：Journal of periodontal research

authors： Lu HK,Lee SY,Lin FP

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interleukin (IL)-32, which has been recently reported to be associated with periodontitis, has been suggested to have pleiotropic effect due to its 9 different isoforms. The aim of this study was to investigate the levels of IL-32α, IL-32β, IL-32γ, IL-32δ isoforms in gingival crevicular fluid (...

journal_title：Journal of periodontal research

authors： Öngöz Dede F,Gökmenoğlu C,Deveci ET,Çelen S,Avci B,Kara C,Çanakçi V

更新日期：2021-01-01 00:00:00

abstract：:The effectiveness of an ideal antimicrobial agent depends on its ability to kill microbes with minimal toxicity to host cells. Depending on the treatment regimen, antimicrobial agents come into contact with host cells for various intervals of time. Sanguinarium (SANG), chlorhexidine (CHX) and tetracycline (TET) are 3 ...

journal_title：Journal of periodontal research

authors： Agarwal S,Piesco NP,Peterson DE,Charon J,Suzuki JB,Godowski KC,Southard GL

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In the oral cavity, the mucosal tissues may develop a number of different pathological conditions, such as inflammatory diseases (gingivitis, periodontitis) and autoimmune disorders (eg, oral lichen planus) that require therapy. The application of topical drugs is one common therapeutic approa...

journal_title：Journal of periodontal research

authors： Jager J,Obst K,Lohan SB,Viktorov J,Staufenbiel S,Renz H,Unbehauen M,Haag R,Hedtrich S,Teutloff C,Meinke MC,Danker K,Dommisch H

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Mast cells are a prominent cell type in the gingival infiltrate in periodontitis. In this study we examined the expression by gingival mast cells of matrix metalloproteinases, MMP-1, MMP-2, MMP-8 and the tissue inhibitors of metalloproteinases, TIMP-1 and TIMP-2. METHODS:Gingival specimens from 12 human imm...

journal_title：Journal of periodontal research

authors： Naesse EP,Schreurs O,Helgeland K,Schenck K,Steinsvoll S

更新日期：2003-12-01 00:00:00

abstract：:This study investigates a potential role for TGF beta 1 in the pathogenesis of cyclosporin A-induced gingival overgrowth (CsA-OG). TGF beta 1 was localized immunohistochemically in the connective tissue of both normal gingiva and CsA-OG. Intense staining for TGF beta 1 was detected at the tips of the dermal papillae o...

journal_title：Journal of periodontal research

authors： James JA,Irwin CR,Linden GJ

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Proinflammatory cytokines such as interleukin-1beta are known to be synthesized in oral gingivitis and periodontitis and lead to the activation of the transcription factor nuclear factor-kappaB (NF-kappaB). Although numerous effects of interleukin-1beta on mesenchymal cells are known, e.g. up-regu...

journal_title：Journal of periodontal research

authors： Steinberg T,Dannewitz B,Tomakidi P,Hoheisel JD,Müssig E,Kohl A,Nees M

更新日期：2006-10-01 00:00:00

abstract：:Some bacterial antigens such as S. aureus enterotoxins can selectively stimulate T cells that express specific V beta genes of the T cell antigen receptor (TCR). The purpose of this study was to investigate whether or not periodontal bacteria could similarly alter the expression of V beta families within the TCR compl...

journal_title：Journal of periodontal research

authors： Mathur A,Michalowicz B,Yang C,Aeppli D

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Regulation of epithelial cell behavior associated with periodontitis is not well elucidated but many responses will ultimately be regulated by growth factor receptors. Using a rat experimental periodontitis model, protein and gene expression of select growth factor receptors in junctional and p...

journal_title：Journal of periodontal research

authors： Ekuni D,Firth JD,Putnins EE

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Inducible nitric oxide synthase (iNOS) activity is known to regulate the immune response. The present study was carried out to determine the effect of L-N6-(1-iminoethyl)-lysine (L-NIL), an iNOS inhibitor, on the induction of immune response to Actinobacillus actinomycetemcomitans lipopolysacc...

journal_title：Journal of periodontal research

authors： Sosroseno W,Musa M,Ravichandran M,Fikri Ibrahim M,Bird PS,Seymour GJ

更新日期：2007-04-01 00:00:00

abstract：:Black-pigmented bacteria which produce cytotoxic metabolic end-products and cell membrane-associated proteases have been reported to play an important role in the pathogenesis of periodontal diseases. These bacterial virulence factors can be modified by the environmental conditions including nutrients supplied various...

journal_title：Journal of periodontal research

authors： Saito K,Takahashi N,Horiuchi H,Yamada T

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Granulation tissue remodeling and myofibroblastic differentiation are critically important events during wound healing. Tobacco smoking has a detrimental effect in gingival tissue repair. However, studies evaluating the effects of cigarette smoke on these events are lacking. MATERIAL AND METHODS:We used gin...

journal_title：Journal of periodontal research

authors： Romero A,Cáceres M,Arancibia R,Silva D,Couve E,Martínez C,Martínez J,Smith PC

更新日期：2015-06-01 00:00:00

abstract：:The onset and progression of periodontal disease is associated with significant changes in the epithelial component of the attachment complex. From the early to the advanced stages of periodontal disease increased epithelial cell proliferation, migration and invasion into the surrounding connective tissue takes place....

journal_title：Journal of periodontal research

authors： Sanale AR,Firth JD,Uitto VJ,Putnins EE

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Gingival crevicular fluid has been of major interest for many decades as a valuable body fluid that may serve as a source of biomarkers for both periodontal and systemic diseases. Owing to its very small sample size, submicroliter volumes, identification of its protein composition by classical ...

journal_title：Journal of periodontal research

authors： Carneiro LG,Venuleo C,Oppenheim FG,Salih E

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Obesity has been implicated as a risk factor for several chronic health conditions. Recent studies have reported a relationship between obesity and periodontitis, but few studies have investigated this relationship in adolescents. The purpose of the present study was to investigate the relation...

journal_title：Journal of periodontal research

authors： Ekuni D,Yamamoto T,Koyama R,Tsuneishi M,Naito K,Tobe K

更新日期：2008-08-01 00:00:00