Production of trypsin and chymotrypsin inhibitors by oral bacterial isolates.

abstract：BACKGROUND:Mast cells are a prominent cell type in the gingival infiltrate in periodontitis. In this study we examined the expression by gingival mast cells of matrix metalloproteinases, MMP-1, MMP-2, MMP-8 and the tissue inhibitors of metalloproteinases, TIMP-1 and TIMP-2. METHODS:Gingival specimens from 12 human imm...

journal_title：Journal of periodontal research

authors： Naesse EP,Schreurs O,Helgeland K,Schenck K,Steinsvoll S

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The gingiva is the first oral tissue directly exposed to cigarette smoke (CS). Exposure to CS compromises the structure and function of gingival tissue. Damaging or altering the gingival epithelium leads to a compromised protective barrier of the periodontium, resulting in several diseases. The...

journal_title：Journal of periodontal research

authors： Alharbi IA,Rouabhia M

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the presence of factor XIIIa+ dendritic cells and S-100 protein+ Langerhans' cells in the gingival epithelium and connective tissue of periodontal pockets, before and after non-surgical periodontal therapy. BACKGROUND:The microbial flora in periodontal pockets provok...

journal_title：Journal of periodontal research

authors： Dereka XE,Tosios KI,Chrysomali E,Angelopoulou E

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Following tooth extraction, bone resorption is especially severe in cases complicated with buccal dehiscence bone defects. To minimize this, various bone graft materials have been used for alveolar ridge preservation. This study aimed to evaluate additional effects of the concomitant use of rec...

journal_title：Journal of periodontal research

authors： Fukuba S,Akizuki T,Matsuura T,Okada M,Nohara K,Hoshi S,Shujaa Addin A,Iwata T,Izumi Y

更新日期：2020-12-12 00:00:00

abstract：:The aim of the present study was to analyze the cytotoxicity of some bacterial species associated with periodontal diseases. The specificity of cytotoxicity was estimated against cells of various origin and from different individuals. The reference bacteria were Actinobacillus actinomycetemcomitans, Porphyromonas ging...

journal_title：Journal of periodontal research

authors： Johansson A,Bergenholtz A,Holm SE

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In periodontitis, matrix metalloproteinases (MMPs) are upregulated in response to locally released inflammatory cytokines, resulting in pathologic processes. Roxithromycin is a 14-membered ring macrolide antibiotic with broad-spectrum antibacterial effects against oral pathogens and immunomodul...

journal_title：Journal of periodontal research

authors： Oyama T,Matsushita K,Sakuta T,Tokuda M,Tatsuyama S,Nagaoka S,Torii M

更新日期：2007-02-01 00:00:00

abstract：:We investigated the co-localization of lysosomal cathepsins B, H and L, and horseradish peroxidase (HRP) in junctional epithelial (JE) cells both as a fluid-phase endocytotic marker to demonstrate the fluid-phase endocytotic capacity of JE cells, and to understand the morphological relationships of the endocytosed for...

journal_title：Journal of periodontal research

authors： Yamaza T,Kido MA,Kiyoshima T,Nishimura Y,Himeno M,Tanaka T

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Treponema denticola is a key pathogen associated with periodontitis, a chronic inflammatory disease affecting tooth-supporting tissues. In the present study, we investigated the response of human macrophage-like cells to stimulation by peptidoglycan isolated from T. denticola. We also studied t...

journal_title：Journal of periodontal research

authors： Tanabe SI,Bodet C,Grenier D

更新日期：2009-08-01 00:00:00

abstract：:The cytolethal distending toxin (Cdt) of Actinobacillus actinomycetemcomitans, a periodontal pathogen, is a newly described cytotoxin with immunosuppressive properties, capable of causing cell cycle arrest of lymphocytes. The objectives of this study were to investigate the occurrence of A. actinomycetemcomitans with ...

journal_title：Journal of periodontal research

authors： Tan KS,Song KP,Ong G

更新日期：2002-08-01 00:00:00

abstract：:The effectiveness of an ideal antimicrobial agent depends on its ability to kill microbes with minimal toxicity to host cells. Depending on the treatment regimen, antimicrobial agents come into contact with host cells for various intervals of time. Sanguinarium (SANG), chlorhexidine (CHX) and tetracycline (TET) are 3 ...

journal_title：Journal of periodontal research

authors： Agarwal S,Piesco NP,Peterson DE,Charon J,Suzuki JB,Godowski KC,Southard GL

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cannabinoid receptor CB2, expressed in osteoblasts and osteoclasts, plays a crucial role in the regulation of bone metabolism. Since periodontal ligament (PDL) cells can differentiate into osteoblasts, this study was undertaken to investigate CB2 expression and the effect of CB2 activation on o...

journal_title：Journal of periodontal research

authors： Qian H,Zhao Y,Peng Y,Han C,Li S,Huo N,Ding Y,Duan Y,Xiong L,Sang H

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Connective tissue grafts are frequently applied, together with Emdogain(®) , for root coverage. However, it is unknown whether fibroblasts from the gingiva and from the palate respond similarly to Emdogain. The aim of this study was therefore to evaluate the effect of Emdogain(®) on fibroblasts...

journal_title：Journal of periodontal research

authors： Gruber R,Stähli A,Miron RJ,Bosshardt DD,Sculean A

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Inducible nitric oxide synthase (iNOS) activity is known to regulate the immune response. The present study was carried out to determine the effect of L-N6-(1-iminoethyl)-lysine (L-NIL), an iNOS inhibitor, on the induction of immune response to Actinobacillus actinomycetemcomitans lipopolysacc...

journal_title：Journal of periodontal research

authors： Sosroseno W,Musa M,Ravichandran M,Fikri Ibrahim M,Bird PS,Seymour GJ

更新日期：2007-04-01 00:00:00

abstract：:Vascularization of the periodontal ligament was examined in developing upper first molars of rats from 5 to 30 d after birth with light and scanning electron microscopy. Formation of the vascular network in the periodontal ligament (PDL) started with the beginning of root formation. The PDL vessels derived from the ba...

journal_title：Journal of periodontal research

authors： Tsukada H,Ishikawa H,Nakamura S,Yoshida S

更新日期：2000-08-01 00:00:00

abstract：:This study investigates a potential role for TGF beta 1 in the pathogenesis of cyclosporin A-induced gingival overgrowth (CsA-OG). TGF beta 1 was localized immunohistochemically in the connective tissue of both normal gingiva and CsA-OG. Intense staining for TGF beta 1 was detected at the tips of the dermal papillae o...

journal_title：Journal of periodontal research

authors： James JA,Irwin CR,Linden GJ

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:  The junctional epithelium provides the front-line defense against periodontal bacterial infection. The migration of neutrophils into the junctional epithelium might represent a protective reaction against bacterial infections. However, neutrophils penetrate into the junctional epithelium even...

journal_title：Journal of periodontal research

authors： Tsukamoto Y,Usui M,Yamamoto G,Takagi Y,Tachikawa T,Yamamoto M,Nakamura M

更新日期：2012-12-01 00:00:00

abstract：:Numerous studies report that water fluoridation reduces caries in children, but little current evidence exists about fluoridation's effects on the periodontal health of adults. To address this issue, we estimated fluoridation effects on periodontal disease among 1066 Washington state employees and their spouses, aged ...

journal_title：Journal of periodontal research

authors： Grembowski D,Fiset L,Spadafora A,Milgrom P

更新日期：1993-05-01 00:00:00

abstract：:This study compared a rapid, colorimetric DNA probe assay designed to be performed in a dental office within 40 min, with anaerobic culture and indirect immunofluorescence microscopy (IFM) for detection of Bacteroides forsythus and Porphyromonas gingivalis in subgingival plaque samples. The DNA probe assay used the Pe...

journal_title：Journal of periodontal research

authors： Tanner AC,Maiden MF,Zambon JJ,Thoren GS,Kent RL Jr

更新日期：1998-02-01 00:00:00

abstract：:Materials used in guided tissue regeneration were examined in an in vitro model for regenerating human junctional epithelium. The extent of epithelial migration from gingival explants (epibolus) between the explant and an experimental substratum was significantly greater with a Millipore filter (HA) than with a teflon...

journal_title：Journal of periodontal research

authors： Salonen JI,Persson GR

更新日期：1990-07-01 00:00:00

abstract：:Quantitative assessment of osseous changes attributable to periodontal disease is made possible by digital subtraction radiography. Tissues through which x rays travel to produce dental radiographs essential to this process alter the energy spectrum of the beam such that calibration errors result when densitometry is ...

journal_title：Journal of periodontal research

authors： Webber RL,Tzukert A,Ruttimann U

更新日期：1989-01-01 00:00:00

abstract：:The formation of new cementum is an important issue in clinical periodontology, as cementum is required to provide attachment for newly formed periodontal tissues to the root surface. In this study a model of cementogenesis in vitro was used in order to test the effects of root surface demineralization on the migratio...

journal_title：Journal of periodontal research

authors： Tenorio D,Foyle DM,Hughes FJ

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to evaluate the effect of radiotherapy on the osseointegration of dental implants in the tibia and the action of platelet-rich plasma (PRP) as an adjuvant therapy. MATERIAL AND METHODS:A total of 18 rabbits received two implants in each tibial epiphysis, totalizing 7...

journal_title：Journal of periodontal research

authors： Ocaña RP,Rabelo GD,Sassi LM,Rodrigues VP,Alves FA

更新日期：2017-06-01 00:00:00

abstract：:This study uses cytokeratins (CK) as markers to investigate the phenotype of the junctional epithelium (JE) in partially erupted human teeth. The gingival samples, which were clinically healthy, were carefully dissected from the teeth. Cryostat sections were cut for histological staining, immunofluorescence microscopy...

journal_title：Journal of periodontal research

authors： Feghali-Assaly M,Sawaf MH,Serres G,Forest N,Ouhayoun JP

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES AND BACKGROUND:Endothelin-1 (ET-1) is a 21-amino acid peptide with multifunctional regulation. ET-1 expresses in various cells during inflammation. The present study aimed to examine the ET-1 expression in oral epithelial cells after infection with the periodontal pathogen and to investigate the presence of ...

journal_title：Journal of periodontal research

authors： Yamamoto E,Awano S,Koseki T,Ansai T,Takehara T

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Neutrophils are the primary white blood cells that are recruited to fight the initial phases of microbial infections. While healthy norms have been determined for circulating blood neutrophil counts in order to identify patients with suspected systemic infections, the levels of oral neutrophils...

journal_title：Journal of periodontal research

authors： Landzberg M,Doering H,Aboodi GM,Tenenbaum HC,Glogauer M

更新日期：2015-06-01 00:00:00

abstract：:Recently, nitric oxide (NO) has been shown to be vital in inflammatory processes. Nitric oxide synthase (NOS) exists in three different isoforms, two constitutively produced with physiological roles, and an inducible form, iNOS, which is involved in inflammation. This study examined the localisation of iNOS in biopsie...

journal_title：Journal of periodontal research

authors： Lappin DF,Kjeldsen M,Sander L,Kinane DF

更新日期：2000-12-01 00:00:00

abstract：:Prevotella intermedia has recently been re-defined and a new species, Prevotella nigrescens has been proposed. However, there is little data available on the incidence of these new species in periodontal health or disease. Black-pigmented anaerobes isolated from diseased and healthy subgingival sites were identified b...

journal_title：Journal of periodontal research

authors： Teanpaisan R,Douglas CW,Walsh TF

更新日期：1995-07-01 00:00:00

abstract：:The cellular heterogeneity of Malassez epithelium (ME) residing in the periodontal ligament has recently been reported, and the presence and coexistence of the neuropeptides calcitonin gene-related peptide (CGRP), substance P (SP) and vasoactive intestinal peptide (VIP) in single cells in ME has been shown (1). Howeve...

journal_title：Journal of periodontal research

authors： Tadokoro O,Maeda T,Heyeraas KJ,Vandevska-Radunovic V,Kozawa Y,Hals Kvinnsland I

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:During cyclosporine-induced gingival overgrowth, the homeostatic balance of gingival connective tissue is disrupted leading to fibrosis. Galectins are glycan-binding proteins that can modulate a variety of cellular processes including fibrosis in several organs. Here, we study the role of galec...

journal_title：Journal of periodontal research

authors： Smith PC,Metz C,de la Peña A,Oyanadel C,Avila P,Arancibia R,Vicuña L,Retamal C,Barake F,González A,Soza A

更新日期：2020-10-01 00:00:00

abstract：AIM:This subgroup analysis of a 12-week randomized, double-blind, and two-center trial aimed to evaluate whether two different toothpaste formulations can differentially modulate the dental microbiome. MATERIAL AND METHODS:Forty one mild to moderate periodontitis patients used as an adjunct to periodontal treatment ei...

journal_title：Journal of periodontal research

authors： Hagenfeld D,Prior K,Harks I,Jockel-Schneider Y,May TW,Harmsen D,Schlagenhauf U,Ehmke B

更新日期：2019-08-01 00:00:00