Implant osseointegration in irradiated bone: an experimental study.

abstract：:Interleukin-1 (IL-1) molecules, IL-1 alpha and IL-1 beta are cytokines involved in the acute-phase response against infection and in the pathogenesis of periodontal destruction. Administration of exogenous IL-1 receptor antagonist (IL-1ra) is effective in reducing the inflammatory reactions mediated by IL-1. However, ...

journal_title：Journal of periodontal research

authors： Ishihara Y,Nishihara T,Kuroyanagi T,Shirozu N,Yamagishi E,Ohguchi M,Koide M,Ueda N,Amano K,Noguchi T

更新日期：1997-08-01 00:00:00

abstract：:The cytolethal distending toxin (Cdt) of Actinobacillus actinomycetemcomitans, a periodontal pathogen, is a newly described cytotoxin with immunosuppressive properties, capable of causing cell cycle arrest of lymphocytes. The objectives of this study were to investigate the occurrence of A. actinomycetemcomitans with ...

journal_title：Journal of periodontal research

authors： Tan KS,Song KP,Ong G

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVES:Heat shock protein (HSP) can be utilized as a vaccine to cross-protect against multiple pathogenic species. The present study was performed to evaluate Porphyromonas gingivalis heat shock protein 60 (HSP60) as a vaccine candidate to inhibit multiple bacteria-induced alveolar bone loss. MATERIAL AND METHODS:...

journal_title：Journal of periodontal research

authors： Lee JY,Yi NN,Kim US,Choi JS,Kim SJ,Choi JI

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Biofilm formation occurs through the events of cooperative growth and competitive survival among multiple species. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans are important periodontal pathogens. The aim of this study was to demonstrate competitive or cooperative interact...

journal_title：Journal of periodontal research

authors： Takasaki K,Fujise O,Miura M,Hamachi T,Maeda K

更新日期：2013-06-01 00:00:00

abstract：:The formation of new cementum is an important issue in clinical periodontology, as cementum is required to provide attachment for newly formed periodontal tissues to the root surface. In this study a model of cementogenesis in vitro was used in order to test the effects of root surface demineralization on the migratio...

journal_title：Journal of periodontal research

authors： Tenorio D,Foyle DM,Hughes FJ

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:It remains controversial whether or not the junctional epithelium cells that are directly attached to teeth migrate on the enamel surface, as those cells are able to adhere firmly to the enamel. The aim of this study was to investigate the expression patterns of laminin gamma(2), integrin beta(...

journal_title：Journal of periodontal research

authors： Sugisawa M,Masaoka T,Enokiya Y,Muramatsu T,Hashimoto S,Yamada S,Shimono M

更新日期：2010-04-01 00:00:00

abstract：:This study compared a rapid, colorimetric DNA probe assay designed to be performed in a dental office within 40 min, with anaerobic culture and indirect immunofluorescence microscopy (IFM) for detection of Bacteroides forsythus and Porphyromonas gingivalis in subgingival plaque samples. The DNA probe assay used the Pe...

journal_title：Journal of periodontal research

authors： Tanner AC,Maiden MF,Zambon JJ,Thoren GS,Kent RL Jr

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Periodontal disease has been described as playing a role in the atherosclerosis process, and its relation with intimal thickness and vascular endothelial function (EF) has been investigated. The present study sought to determine whether there are differences in parameters of arterial stiffness ...

journal_title：Journal of periodontal research

authors： Nicolosi LN,Lewin PG,Rudzinski JJ,Pompeo M,Guanca F,Rodríguez P,Gelpi RJ,Rubio MC

更新日期：2017-02-01 00:00:00

abstract：:The matrix metalloproteinases (MMPs) collagenase, gelatinase A (72 kDa gelatinase), stromelysin, and their specific inhibitor TIMP-1 (tissue inhibitor of metalloproteinases), were immunolocalized using specific polyclonal antisera in gingival tissues from 21 patients with chronic inflammatory periodontal disease. Mono...

journal_title：Journal of periodontal research

authors： Meikle MC,Hembry RM,Holley J,Horton C,McFarlane CG,Reynolds JJ

更新日期：1994-03-01 00:00:00

abstract：:The effectiveness of an ideal antimicrobial agent depends on its ability to kill microbes with minimal toxicity to host cells. Depending on the treatment regimen, antimicrobial agents come into contact with host cells for various intervals of time. Sanguinarium (SANG), chlorhexidine (CHX) and tetracycline (TET) are 3 ...

journal_title：Journal of periodontal research

authors： Agarwal S,Piesco NP,Peterson DE,Charon J,Suzuki JB,Godowski KC,Southard GL

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cigarette smoking has detrimental effects on periodontal tissue, and is known to be a risk factor for periodontal disease, including the loss of alveolar bone and ligament tissue. However, the direct effects of cigarette smoking on periodontal tissue remain unclear. Recently, we demonstrated th...

journal_title：Journal of periodontal research

authors： Monnouchi S,Maeda H,Yuda A,Serita S,Wada N,Tomokiyo A,Akamine A

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In the oral cavity, the mucosal tissues may develop a number of different pathological conditions, such as inflammatory diseases (gingivitis, periodontitis) and autoimmune disorders (eg, oral lichen planus) that require therapy. The application of topical drugs is one common therapeutic approa...

journal_title：Journal of periodontal research

authors： Jager J,Obst K,Lohan SB,Viktorov J,Staufenbiel S,Renz H,Unbehauen M,Haag R,Hedtrich S,Teutloff C,Meinke MC,Danker K,Dommisch H

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Lipopolysaccharide (LPS) on the cell wall of periodontal pathogens is a major mediator of the inflammatory response and can enhance alveolar bone resorption in periodontitis. Bone sialoprotein is an early marker of osteoblast differentiation. The proinflammatory cytokine, interleukin-8 (IL-8), ...

journal_title：Journal of periodontal research

authors： Zhang Y,Li X

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Elevated nitric oxide (NO) has been associated with destructive periodontal disease. The aim of the present study was to test the hypothesis that exogenous NO may inhibit a protective immune response to Aggregatibacter actinomycetemcomitans lipopolysaccharide (LPS) in a murine model. MATERIAL ...

journal_title：Journal of periodontal research

authors： Sosroseno W,Bird PS,Seymour GJ

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In periodontitis, matrix metalloproteinases (MMPs) are upregulated in response to locally released inflammatory cytokines, resulting in pathologic processes. Roxithromycin is a 14-membered ring macrolide antibiotic with broad-spectrum antibacterial effects against oral pathogens and immunomodul...

journal_title：Journal of periodontal research

authors： Oyama T,Matsushita K,Sakuta T,Tokuda M,Tatsuyama S,Nagaoka S,Torii M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Osteonecrosis of the jaw (ONJ) is associated with bisphosphonate (BP) therapy. BPs alter osteoblast production of mediators of osteoclastogenesis, including interleukin (IL)-6, RANKL and osteoprotegerin (OPG), a RANKL antagonist. This can inhibit bone turnover and lead to necrosis. There is lit...

journal_title：Journal of periodontal research

authors： Tipton DA,Seshul BA,Dabbous MKh

更新日期：2011-02-01 00:00:00

abstract：:Glycosaminoglycans in normal and cyclosporin-induced gingival overgrowth were extracted by papain digestion and purified by Mono Q-FPLC chromatography. The purified glycosaminoglycans were analyzed by agarose gel electrophoresis and by the pattern of degradation products formed by chondroitin lyases on HPLC chromatogr...

journal_title：Journal of periodontal research

authors： Rocha LA,Martins RC,Werneck CC,Feres-Filho EJ,Silva LC

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Several studies have hypothesized that periodontal disease may increase the risk of pre-eclampsia. The correlation between the two diseases would probably be based on hypertension-related cytokine release in the local periodontal environment. The aim of this study was to evaluate the associatio...

journal_title：Journal of periodontal research

authors： Politano GT,Passini R,Nomura ML,Velloso L,Morari J,Couto E

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Activated potassium channels were found to be strongly correlated with gingival overgrowth (GO) phenotype as we reviewed syndromic hereditary gingival fibromatosis (HGF). Nevertheless, the functional roles of potassium channels in gingival fibrosis or gingival overgrowth remained uncovered. The...

journal_title：Journal of periodontal research

authors： Gao Q,Yang C,Meng L,Wang Z,Chen D,Peng Y,Yang K,Bian Z

更新日期：2020-12-31 00:00:00

abstract：:Collagenolysis in periodontitis is thought to be modulated by the expression of three genes, collagenase, tissue inhibitors of metalloproteinases-1 and -2 (TIMP-1 and -2). We assessed the possible difference in TIMP-1, TIMP-2 and collagenase mRNA levels between gingival samples from patients with periodontitis and tho...

journal_title：Journal of periodontal research

authors： Nomura T,Takahashi T,Hara K

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The gingival epithelium is a first line of defense against bacterial challenge. E-cadherin (E-cad) plays an important role in cell-cell adhesion as a barrier in the epithelium. Recently, a decrease in the expression of E-cad has been observed in inflamed gingival tissue. The aims of this study ...

journal_title：Journal of periodontal research

authors： Abe-Yutori M,Chikazawa T,Shibasaki K,Murakami S

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interleukin-6 (IL-6) is a key proinflammatory cytokine that has been considered to be important in the pathogenesis of periodontal disease. Therefore, host-modulatory agents directed at inhibiting IL-6 appear to be beneficial in terms of attenuating periodontal disease progression and potential...

journal_title：Journal of periodontal research

authors： Jin JY,Choi EY,Park HR,Choi JI,Choi IS,Kim SJ

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Porphyromonas gingivalis, a black-pigmented, gram-negative anaerobe, is found in periodontitis lesions and its presence in subgingival plaque significantly increases the risk for periodontitis. We have previously shown that patients with aggressive forms of periodontitis that are seropositive for P. gingival...

journal_title：Journal of periodontal research

authors： Califano JV,Chou D,Lewis JP,Rogers JD,Best AM,Schenkein HA

更新日期：2004-08-01 00:00:00

abstract：:Diploid fibroblasts obtained from explants of human gingiva and maintained in vitro undergo a several-fold decrease in protein and collagen synthesis as a function of increasing donor age. Using drug-induced gingival hyperplasia as a model, we performed experiments to learn whether fibroblasts derived from hyperplasti...

journal_title：Journal of periodontal research

authors： Johnson BD,Narayanan AS,Pieters HP,Page RC

更新日期：1990-03-01 00:00:00

abstract：:The aim of this study was to compare the percentage of vital microorganisms (= microbial vitality) of saliva with that of supragingival plaque both collected at various times during the early phases of de novo plaque formation. Between intervals of optimal oral hygiene, 14 healthy participants refrained from all oral ...

journal_title：Journal of periodontal research

authors： Weiger R,von Ohle C,Decker E,Axmann-Krcmar D,Netuschil L

更新日期：1997-02-01 00:00:00

abstract：:An accumulation of elevated numbers of macrophages (M phi) and Ig producing cells is associated with localized and chronically inflamed gingiva of patients with adult periodontitis. When gingival lymphocytes were isolated from inflamed tissues and examined by flow cytometry, approximately 20-30% of lymphocytes were CD...

journal_title：Journal of periodontal research

authors： Yamamoto M,Fujihashi K,Hiroi T,McGhee JR,Van Dyke TE,Kiyono H

更新日期：1997-01-01 00:00:00

abstract：:This study uses cytokeratins (CK) as markers to investigate the phenotype of the junctional epithelium (JE) in partially erupted human teeth. The gingival samples, which were clinically healthy, were carefully dissected from the teeth. Cryostat sections were cut for histological staining, immunofluorescence microscopy...

journal_title：Journal of periodontal research

authors： Feghali-Assaly M,Sawaf MH,Serres G,Forest N,Ouhayoun JP

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cannabinoid receptor CB2, expressed in osteoblasts and osteoclasts, plays a crucial role in the regulation of bone metabolism. Since periodontal ligament (PDL) cells can differentiate into osteoblasts, this study was undertaken to investigate CB2 expression and the effect of CB2 activation on o...

journal_title：Journal of periodontal research

authors： Qian H,Zhao Y,Peng Y,Han C,Li S,Huo N,Ding Y,Duan Y,Xiong L,Sang H

更新日期：2010-08-01 00:00:00

abstract：:Vascularization of the periodontal ligament was examined in developing upper first molars of rats from 5 to 30 d after birth with light and scanning electron microscopy. Formation of the vascular network in the periodontal ligament (PDL) started with the beginning of root formation. The PDL vessels derived from the ba...

journal_title：Journal of periodontal research

authors： Tsukada H,Ishikawa H,Nakamura S,Yoshida S

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Gingival recession is defined as soft and hard tissue displacement resulting in root surface exposure. The optimal outcome of gingival recession treatment is complete, predictable and long-lasting root coverage with a significant level of tissue regeneration. Tissue engineering, which applies a...

journal_title：Journal of periodontal research

authors： Milinkovic I,Aleksic Z,Jankovic S,Popovic O,Bajic M,Cakic S,Lekovic V

更新日期：2015-06-01 00:00:00